SGTA Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha|This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6449)
Similar Terms
Downloads & Tools

Genes

286 genes differentially expressed following the SGTA gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
FAM153A family with sequence similarity 153, member A 3.49812
GOLGA6C golgin A6 family, member C 3.49812
CRHR1 corticotropin releasing hormone receptor 1 3.49812
ERMN ermin, ERM-like protein 3.49812
OSTN osteocrin 3.49812
BTC betacellulin 3.49812
STARD6 StAR-related lipid transfer (START) domain containing 6 3.49812
RHAG Rh-associated glycoprotein 3.49812
GLP2R glucagon-like peptide 2 receptor 3.49812
NOX3 NADPH oxidase 3 3.49812
CLRN1 clarin 1 3.49812
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 3.49812
PSORS1C2 psoriasis susceptibility 1 candidate 2 3.49812
NDRG1 N-myc downstream regulated 1 3.49812
SLC22A14 solute carrier family 22, member 14 3.49812
ZFP92 ZFP92 zinc finger protein 3.49812
OR13G1 olfactory receptor, family 13, subfamily G, member 1 3.49812
REELD1 reeler domain containing 1 3.49812
H3C14 H3 clustered histone 14 3.49812
ANXA10 annexin A10 3.49812
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 3.49812
DNAH2 dynein, axonemal, heavy chain 2 3.49812
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3.49812
LRRC8C-DT LRRC8C divergent transcript 3.49812
LCN15 lipocalin 15 3.49812
EMCN endomucin 3.49812
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 3.49812
MATN2 matrilin 2 3.45634
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 3.36451
RGS9BP regulator of G protein signaling 9 binding protein 3.36451
CCR7 chemokine (C-C motif) receptor 7 3.36451
MMP28 matrix metallopeptidase 28 3.36451
GPR52 G protein-coupled receptor 52 3.36451
VCX2 variable charge, X-linked 2 3.36451
AGTR1 angiotensin II receptor, type 1 3.36451
TM4SF20 transmembrane 4 L six family member 20 3.36451
TMPRSS11F transmembrane protease, serine 11F 3.36451
OR4F17 olfactory receptor, family 4, subfamily F, member 17 3.36451
ACVRL1 activin A receptor type II-like 1 3.36451
CSNK2A2IP casein kinase 2 subunit alpha' interacting protein 3.36451
SFTPB surfactant protein B 3.36451
C11ORF87 chromosome 11 open reading frame 87 3.36451
PAX8 paired box 8 3.36451
SLC25A41 solute carrier family 25, member 41 3.36451
CLEC19A C-type lectin domain family 19, member A 3.36451
DIO3 deiodinase, iodothyronine, type III 3.36451
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 3.36451
TRIM10 tripartite motif containing 10 3.36451
TTLL8 tubulin tyrosine ligase-like family member 8 3.36451
PRELP proline/arginine-rich end leucine-rich repeat protein 3.36451
TRPV6 transient receptor potential cation channel, subfamily V, member 6 3.36451
TMEM71 transmembrane protein 71 3.36451
SLC26A9 solute carrier family 26 (anion exchanger), member 9 3.36451
ACTL10 actin-like 10 3.36451
PTPRC protein tyrosine phosphatase, receptor type, C 3.36451
TMEM40 transmembrane protein 40 3.36451
TRIM31 tripartite motif containing 31 3.36451
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 3.36451
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H 3.36451
MGAT4D MGAT4 family, member D 3.36451
MYH1 myosin, heavy chain 1, skeletal muscle, adult 3.36451
C3AR1 complement component 3a receptor 1 3.36451
SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13 3.36451
ANGPTL8 angiopoietin like 8 3.36451
PLAAT4 phospholipase A and acyltransferase 4 3.36451
DNAAF8 dynein axonemal assembly factor 8 3.36451
CPHXL cytoplasmic polyadenylated homeobox like 3.36451
INSYN1 inhibitory synaptic factor 1 3.36451
CFAP97D2 CFAP97 domain containing 2 3.36451
CIMAP1D CIMAP1 family member D 3.36451
ANKRD42-DT ANKRD42 divergent transcript 3.36451
IMPG2 interphotoreceptor matrix proteoglycan 2 3.36451
GATA1 GATA binding protein 1 (globin transcription factor 1) 3.36451
VIT vitrin 3.36451
MAGEB2 melanoma antigen family B2 3.36451
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 3.36451
AXDND1 axonemal dynein light chain domain containing 1 3.36451
OR8D4 olfactory receptor, family 8, subfamily D, member 4 3.36451
MEIOSIN meiosis initiator 3.36451
CATSPER3 cation channel, sperm associated 3 3.36451
MSX1 msh homeobox 1 3.36451
TACSTD2 tumor-associated calcium signal transducer 2 3.36451
TLR7 toll-like receptor 7 3.36451
TBX3 T-box 3 3.36451
KLRF1 killer cell lectin-like receptor subfamily F, member 1 3.36451
PLEK2 pleckstrin 2 3.36451
GDF6 growth differentiation factor 6 3.36451
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 3.36451
CNTN6 contactin 6 3.36451
LITAFD LITAF domain containing 3.36451
ITGA8 integrin, alpha 8 3.36451
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 3.36451
ADAM7 ADAM metallopeptidase domain 7 3.36451
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 3.36451
TAS2R50 taste receptor, type 2, member 50 3.36451
CSTA cystatin A (stefin A) 3.36451
SRRM5 serine/arginine repetitive matrix 5 3.36451
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 3.36451
GAL3ST2 galactose-3-O-sulfotransferase 2 3.36451
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 3.36451
NPIPB15 nuclear pore complex interacting protein family, member B15 3.36451
TCF21 transcription factor 21 3.36451
PRSS57 protease, serine, 57 3.36451
ACSM1 acyl-CoA synthetase medium-chain family member 1 3.36451
TMIGD3 transmembrane and immunoglobulin domain containing 3 3.36451
MAEL maelstrom spermatogenic transposon silencer 3.36451
POTEI POTE ankyrin domain family, member I 3.36451
DRD2 dopamine receptor D2 3.36451
DRD5 dopamine receptor D5 3.36451
BCL2A1 BCL2-related protein A1 3.36451
GOLGA8N golgin A8 family, member N 3.36451
GBX2 gastrulation brain homeobox 2 3.36451
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 3.36451
GPR146 G protein-coupled receptor 146 3.36451
IGIP IgA-inducing protein 3.36451
RGS8 regulator of G-protein signaling 8 3.36451
CD27 CD27 molecule 3.36451
SPEF1 sperm flagellar 1 3.36451
C8G complement component 8, gamma polypeptide 3.36451
UTS2R urotensin 2 receptor 3.36451
MUC7 mucin 7, secreted 3.36451
KLK15 kallikrein-related peptidase 15 3.36451
HELT helt bHLH transcription factor 3.36451
DNTT DNA nucleotidylexotransferase 3.36451
C17ORF99 chromosome 17 open reading frame 99 3.36451
ITPKA inositol-trisphosphate 3-kinase A 3.36451
TMEM52B transmembrane protein 52B 3.36451
IRX4 iroquois homeobox 4 3.36451
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 3.36451
CCNO cyclin O 3.36451
OXER1 oxoeicosanoid (OXE) receptor 1 3.36451
CDCP2 CUB domain containing protein 2 3.36451
NR2F1 nuclear receptor subfamily 2, group F, member 1 3.36451
ANGPTL6 angiopoietin-like 6 3.36451
ADAM20 ADAM metallopeptidase domain 20 3.36451
THEM5 thioesterase superfamily member 5 3.36451
CLEC2A C-type lectin domain family 2, member A 3.36451
NPC1L1 NPC1-like 1 3.36451
PITX2 paired-like homeodomain 2 3.36451
TAS2R13 taste receptor, type 2, member 13 3.36451
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 3.36451
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 3.36451
GJA9 gap junction protein, alpha 9, 59kDa 3.36451
TGM4 transglutaminase 4 3.36451
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 3.36451
SPAG6 sperm associated antigen 6 3.36451
PGM5 phosphoglucomutase 5 3.36451
FAM222A family with sequence similarity 222, member A 3.33183
YIPF3 Yip1 domain family, member 3 3.26426
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 3.24667
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 3.22077
WASHC1 WASH complex subunit 1 2.93513
KLC1 kinesin light chain 1 2.88178
LPIN3 lipin 3 2.85805
MORC3 MORC family CW-type zinc finger 3 2.80543
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 2.78507
DBT dihydrolipoamide branched chain transacylase E2 2.73302
MKRN1 makorin ring finger protein 1 2.669
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 2.57482
TGFB3 transforming growth factor, beta 3 2.57482
PHF7 PHD finger protein 7 2.55913
PTP4A3 protein tyrosine phosphatase type IVA, member 3 2.42961
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 2.40396
LAMP5 lysosomal-associated membrane protein family, member 5 2.40289
FXYD2 FXYD domain containing ion transport regulator 2 2.40289
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans) 2.40289
LYSET lysosomal enzyme trafficking factor 2.3865
GPR39 G protein-coupled receptor 39 2.34709
BRICD5 BRICHOS domain containing 5 2.34709
PPP4R1 protein phosphatase 4, regulatory subunit 1 2.34709
H2BC26 H2B clustered histone 26 2.34709
FSCN3 fascin actin-bundling protein 3, testicular 2.34709
TSGA10IP testis specific, 10 interacting protein 2.34709
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 2.34709
SCUBE2 signal peptide, CUB domain, EGF-like 2 2.30966
CRAMP1 cramped chromatin regulator homolog 1 2.28798
NCSTN nicastrin 2.24031
ARMC7 armadillo repeat containing 7 2.23919
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 2.23861
EXOSC1 exosome component 1 2.22418
PANK2 pantothenate kinase 2 2.21592
PIAS3 protein inhibitor of activated STAT, 3 2.21592
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 2.20765
DALRD3 DALR anticodon binding domain containing 3 2.20694
UBAP1 ubiquitin associated protein 1 2.17136
LDHA lactate dehydrogenase A 2.15495
VAV3 vav 3 guanine nucleotide exchange factor 2.15204
PCBP3 poly(rC) binding protein 3 2.15024
ARL8B ADP-ribosylation factor-like 8B 2.14772
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) 2.13928
UPP1 uridine phosphorylase 1 2.12018
RUNDC1 RUN domain containing 1 2.06271
CIMAP3 ciliary microtubule associated protein 3 2.03613
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.03613
MB21D2 Mab-21 domain containing 2 2.02159
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 2.02063
ZBTB9 zinc finger and BTB domain containing 9 2.01709

decreased expression

Symbol Name Standardized Value
WDR93 WD repeat domain 93 -3.42735
STXBP6 syntaxin binding protein 6 (amisyn) -3.36451
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.36451
CEP44 centrosomal protein 44kDa -3.36451
DNAAF11 dynein axonemal assembly factor 11 -3.34534
ZNF534 zinc finger protein 534 -3.33183
SFXN3 sideroflexin 3 -3.33183
RUFY4 RUN and FYVE domain containing 4 -3.33183
GMNC geminin coiled-coil domain containing -3.33183
MUSK muscle, skeletal, receptor tyrosine kinase -3.33183
RNF222 ring finger protein 222 -3.33183
FLI1 Fli-1 proto-oncogene, ETS transcription factor -3.33183
TRIM74 tripartite motif containing 74 -3.33183
TMIE transmembrane inner ear -3.33183
RGL4 ral guanine nucleotide dissociation stimulator-like 4 -3.33183
ADAMTSL5 ADAMTS-like 5 -3.33183
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -3.33183
SP6 Sp6 transcription factor -3.33183
LRRC63 leucine rich repeat containing 63 -3.33183
C1ORF146 chromosome 1 open reading frame 146 -3.33183
STAB1 stabilin 1 -3.33183
C17ORF107 chromosome 17 open reading frame 107 -3.33183
MZB1 marginal zone B and B1 cell-specific protein -3.33183
PCDHB9 protocadherin beta 9 -3.33183
PLEKHN1 pleckstrin homology domain containing, family N member 1 -3.33183
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 -3.33183
LURAP1L leucine rich adaptor protein 1-like -3.33183
RTL9 retrotransposon Gag like 9 -3.33183
PGC progastricsin (pepsinogen C) -3.33183
PRRT4 proline-rich transmembrane protein 4 -3.33183
ZNF703 zinc finger protein 703 -3.33183
IQUB IQ motif and ubiquitin domain containing -3.2069
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -2.98549
CYB5RL cytochrome b5 reductase-like -2.94801
WIZ widely interspaced zinc finger motifs -2.88923
TOMM34 translocase of outer mitochondrial membrane 34 -2.85805
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 -2.81203
RBM14 RNA binding motif protein 14 -2.8117
WDR88 WD repeat domain 88 -2.68723
MBTPS2 membrane-bound transcription factor peptidase, site 2 -2.66641
GTF3C6 general transcription factor IIIC, polypeptide 6, alpha 35kDa -2.66641
DSCC1 DNA replication and sister chromatid cohesion 1 -2.59766
GNG2 guanine nucleotide binding protein (G protein), gamma 2 -2.51616
GLB1L2 galactosidase, beta 1-like 2 -2.50468
LIME1 Lck interacting transmembrane adaptor 1 -2.50468
SAC3D1 SAC3 domain containing 1 -2.46619
VWA5B1 von Willebrand factor A domain containing 5B1 -2.44976
FBRSL1 fibrosin-like 1 -2.3865
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) -2.3597
NTMT2 N-terminal Xaa-Pro-Lys N-methyltransferase 2 -2.34709
LEKR1 leucine, glutamate and lysine rich 1 -2.34709
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 -2.34709
SYCP3 synaptonemal complex protein 3 -2.34709
TXNL4B thioredoxin-like 4B -2.34607
SCRIB scribbled planar cell polarity protein -2.34133
IL12RB2 interleukin 12 receptor, beta 2 -2.34101
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -2.30472
PODNL1 podocan-like 1 -2.30472
TMEM236 transmembrane protein 236 -2.30472
KIF24 kinesin family member 24 -2.29702
GRM7 glutamate receptor, metabotropic 7 -2.27326
IDO2 indoleamine 2,3-dioxygenase 2 -2.25371
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -2.24858
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial -2.24858
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -2.24788
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -2.24788
ACOX1 acyl-CoA oxidase 1, palmitoyl -2.24031
ZDHHC18 zinc finger, DHHC-type containing 18 -2.24031
GPC5 glypican 5 -2.23861
FGFR1 fibroblast growth factor receptor 1 -2.21164
ACSBG2 acyl-CoA synthetase bubblegum family member 2 -2.20834
SP140L SP140 nuclear body protein-like -2.20834
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like -2.1798
CREB3L4 cAMP responsive element binding protein 3-like 4 -2.15495
RADIL Ras association and DIL domains -2.14391
ERCC8 excision repair cross-complementation group 8 -2.13928
OSBPL11 oxysterol binding protein-like 11 -2.13676
GAS7 growth arrest-specific 7 -2.11872
NQO1 NAD(P)H dehydrogenase, quinone 1 -2.09584
RUNX1 runt-related transcription factor 1 -2.05611
EML6 echinoderm microtubule associated protein like 6 -2.05611
SLC12A8 solute carrier family 12, member 8 -2.03475
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa -2.03471
LSG1 large 60S subunit nuclear export GTPase 1 -2.03471
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -2.02511
DHPS deoxyhypusine synthase -2.02505
RPAP1 RNA polymerase II associated protein 1 -2.01665
CSRNP3 cysteine-serine-rich nuclear protein 3 -2.01338
RPL22L1 ribosomal protein L22-like 1 -2.01005