| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/72188643 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in SH-4-54 relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYBA | cytochrome b-245, alpha polypeptide | 0.56 |
| XIRP2 | xin actin binding repeat containing 2 | 0.42 |
| EVA1C | eva-1 homolog C (C. elegans) | 0.4 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | 0.38 |
| HMGXB4 | HMG box domain containing 4 | 0.37 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.36 |
| BOLA1 | bolA family member 1 | 0.36 |
| ZNF689 | zinc finger protein 689 | 0.35 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.35 |
| LIME1 | Lck interacting transmembrane adaptor 1 | 0.33 |
| BAG4 | BCL2-associated athanogene 4 | 0.32 |
| B2M | beta-2-microglobulin | 0.32 |
| NFYB | nuclear transcription factor Y, beta | 0.32 |
| MT2A | metallothionein 2A | 0.31 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.3 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | 0.3 |
| MCM9 | minichromosome maintenance complex component 9 | 0.29 |
| IL17RB | interleukin 17 receptor B | 0.28 |
| CALU | calumenin | 0.28 |
| DPY30 | dpy-30 homolog (C. elegans) | 0.28 |
| MYOM3 | myomesin 3 | 0.27 |
| H3C1 | H3 clustered histone 1 | 0.27 |
| C9ORF72 | chromosome 9 open reading frame 72 | 0.27 |
| WRB | tryptophan rich basic protein | 0.27 |
| TXNL4B | thioredoxin-like 4B | 0.27 |
| ZNF451 | zinc finger protein 451 | 0.26 |
| CCDC84 | coiled-coil domain containing 84 | 0.26 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) | 0.26 |
| ZNF268 | zinc finger protein 268 | 0.26 |
| PPT1 | palmitoyl-protein thioesterase 1 | 0.25 |
| LYST | lysosomal trafficking regulator | 0.25 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 | 0.24 |
| ZNF410 | zinc finger protein 410 | 0.24 |
| TPM2 | tropomyosin 2 (beta) | 0.24 |
| IFFO2 | intermediate filament family orphan 2 | 0.24 |
| ABLIM2 | actin binding LIM protein family, member 2 | 0.24 |
| TPM4 | tropomyosin 4 | 0.24 |
| ZNF175 | zinc finger protein 175 | 0.23 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) | 0.23 |
| ZNF124 | zinc finger protein 124 | 0.23 |
| HMOX1 | heme oxygenase 1 | 0.23 |
| OSER1 | oxidative stress responsive serine-rich 1 | 0.22 |
| INVS | inversin | 0.22 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 | 0.22 |
| HECW2 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 | 0.22 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.22 |
| SNRPF | small nuclear ribonucleoprotein polypeptide F | 0.21 |
| E2F2 | E2F transcription factor 2 | 0.21 |
| COA4 | cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) | 0.21 |
| C1D | C1D nuclear receptor corepressor | 0.21 |
| AURKAIP1 | aurora kinase A interacting protein 1 | 0.21 |
| TPM3 | tropomyosin 3 | 0.21 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.21 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | 0.21 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.21 |
| PLD6 | phospholipase D family, member 6 | 0.21 |
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | 0.21 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.21 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.21 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) | 0.21 |
| FAM117A | family with sequence similarity 117, member A | 0.21 |
| CHCHD2P9 | coiled-coil-helix-coiled-coil-helix domain containing 2 pseudogene 9 | 0.21 |
| MGA | MGA, MAX dimerization protein | 0.21 |
| SAC3D1 | SAC3 domain containing 1 | 0.21 |
| LRRC7 | leucine rich repeat containing 7 | 0.21 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 | 0.2 |
| ATMIN | ATM interactor | 0.2 |
| SMIM26 | small integral membrane protein 26 | 0.2 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | 0.2 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | 0.2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.2 |
| C5ORF51 | chromosome 5 open reading frame 51 | 0.2 |
| AEN | apoptosis enhancing nuclease | 0.2 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) | 0.2 |
| BMP8A | bone morphogenetic protein 8a | 0.2 |
| COPZ1 | coatomer protein complex, subunit zeta 1 | 0.2 |
| RPGR | retinitis pigmentosa GTPase regulator | 0.2 |
| ABCA13 | ATP-binding cassette, sub-family A (ABC1), member 13 | 0.2 |
| C12ORF60 | chromosome 12 open reading frame 60 | 0.2 |
| NGFR | nerve growth factor receptor | 0.2 |
| USP30 | ubiquitin specific peptidase 30 | 0.2 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | 0.2 |
| JAK3 | Janus kinase 3 | 0.2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) | 0.19 |
| CAB39L | calcium binding protein 39-like | 0.19 |
| ZNF692 | zinc finger protein 692 | 0.19 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.19 |
| RPL36AL | ribosomal protein L36a-like | 0.19 |
| ZNF581 | zinc finger protein 581 | 0.19 |
| CCAR2 | cell cycle and apoptosis regulator 2 | 0.19 |
| PROSER3 | proline and serine rich 3 | 0.19 |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.19 |
| FAAP24 | FA core complex associated protein 24 | 0.19 |
| ABHD17B | abhydrolase domain containing 17B | 0.19 |
| PTMA | prothymosin, alpha | 0.19 |
| FAM219A | family with sequence similarity 219, member A | 0.18 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | 0.18 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) | 0.18 |
| DUSP14 | dual specificity phosphatase 14 | 0.18 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.69 |
| CNTRL | centriolin | -2.18 |
| RNF111 | ring finger protein 111 | -2.11 |
| GJC1 | gap junction protein, gamma 1, 45kDa | -1.2 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -1.05 |
| BHMT | betaine--homocysteine S-methyltransferase | -0.89 |
| SLC6A17 | solute carrier family 6 (neutral amino acid transporter), member 17 | -0.86 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.84 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow | -0.82 |
| FGB | fibrinogen beta chain | -0.74 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 | -0.74 |
| ALDH1L2 | aldehyde dehydrogenase 1 family, member L2 | -0.73 |
| TSPAN3 | tetraspanin 3 | -0.7 |
| ECM1 | extracellular matrix protein 1 | -0.65 |
| NCKAP1L | NCK-associated protein 1-like | -0.64 |
| ALDOB | aldolase B, fructose-bisphosphate | -0.64 |
| DMGDH | dimethylglycine dehydrogenase | -0.57 |
| EPN3 | epsin 3 | -0.56 |
| PIP | prolactin-induced protein | -0.55 |
| MIEF2 | mitochondrial elongation factor 2 | -0.53 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 | -0.52 |
| IL6ST | interleukin 6 signal transducer | -0.51 |
| FGA | fibrinogen alpha chain | -0.51 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.5 |
| DNAAF3 | dynein, axonemal, assembly factor 3 | -0.5 |
| ASB13 | ankyrin repeat and SOCS box containing 13 | -0.49 |
| CD63 | CD63 molecule | -0.49 |
| DENND4A | DENN/MADD domain containing 4A | -0.49 |
| FN1 | fibronectin 1 | -0.48 |
| HEXD | hexosaminidase D | -0.48 |
| ZDHHC8 | zinc finger, DHHC-type containing 8 | -0.48 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | -0.48 |
| SUMO2 | small ubiquitin-like modifier 2 | -0.48 |
| EEF1AKMT2 | EEF1A lysine methyltransferase 2 | -0.47 |
| DAPK2 | death-associated protein kinase 2 | -0.47 |
| PARD6A | par-6 family cell polarity regulator alpha | -0.45 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.44 |
| PRXL2A | peroxiredoxin like 2A | -0.44 |
| WNT10B | wingless-type MMTV integration site family, member 10B | -0.44 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.43 |
| ZSCAN29 | zinc finger and SCAN domain containing 29 | -0.43 |
| GLCCI1 | glucocorticoid induced 1 | -0.43 |
| FGG | fibrinogen gamma chain | -0.43 |
| DBNL | drebrin-like | -0.42 |
| SHFL | shiftless antiviral inhibitor of ribosomal frameshifting | -0.42 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | -0.42 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.42 |
| RAB19 | RAB19, member RAS oncogene family | -0.42 |
| COL2A1 | collagen, type II, alpha 1 | -0.42 |
| TMEM135 | transmembrane protein 135 | -0.4 |
| RELL1 | RELT-like 1 | -0.4 |
| ATP9B | ATPase, class II, type 9B | -0.4 |
| RNFT2 | ring finger protein, transmembrane 2 | -0.4 |
| HAL | histidine ammonia-lyase | -0.4 |
| TMEM59 | transmembrane protein 59 | -0.39 |
| CBX7 | chromobox homolog 7 | -0.38 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.38 |
| TNK2 | tyrosine kinase, non-receptor, 2 | -0.37 |
| CPE | carboxypeptidase E | -0.37 |
| TNS2 | tensin 2 | -0.37 |
| CMTM4 | CKLF-like MARVEL transmembrane domain containing 4 | -0.37 |
| BMT2 | base methyltransferase of 25S rRNA 2 homolog | -0.37 |
| TANGO2 | transport and golgi organization 2 homolog (Drosophila) | -0.36 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.36 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.36 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.36 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 | -0.35 |
| S100A14 | S100 calcium binding protein A14 | -0.35 |
| TMPO | thymopoietin | -0.35 |
| COL7A1 | collagen, type VII, alpha 1 | -0.34 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 | -0.34 |
| PBLD | phenazine biosynthesis-like protein domain containing | -0.34 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.34 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 | -0.34 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 | -0.34 |
| FZD1 | frizzled class receptor 1 | -0.34 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 | -0.34 |
| DPYD | dihydropyrimidine dehydrogenase | -0.34 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.33 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 | -0.33 |
| HBA1 | hemoglobin, alpha 1 | -0.33 |
| EVL | Enah/Vasp-like | -0.33 |
| CBARP | CACN subunit beta associated regulatory protein | -0.33 |
| CROCC2 | ciliary rootlet coiled-coil, rootletin family member 2 | -0.33 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 | -0.33 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.33 |
| ZSWIM7 | zinc finger, SWIM-type containing 7 | -0.32 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.32 |
| SELENBP1 | selenium binding protein 1 | -0.32 |
| PEMT | phosphatidylethanolamine N-methyltransferase | -0.32 |
| DIPK1A | divergent protein kinase domain 1A | -0.31 |
| DXO | decapping exoribonuclease | -0.31 |
| KDM6B | lysine (K)-specific demethylase 6B | -0.31 |
| CDC42SE2 | CDC42 small effector 2 | -0.31 |
| CST6 | cystatin E/M | -0.31 |
| BBS7 | Bardet-Biedl syndrome 7 | -0.31 |
| CLDN3 | claudin 3 | -0.31 |
| MEGF8 | multiple EGF-like-domains 8 | -0.31 |
| RGN | regucalcin | -0.31 |
| BBS10 | Bardet-Biedl syndrome 10 | -0.31 |
