| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | SH2 domain containing 1A|This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4068) |
| External Link | https://ncbi.nlm.nih.gov/gene/4068 |
| Similar Terms | |
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499 genes differentially expressed following the SH2D1A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0116784 |
| HBB | hemoglobin, beta | 0.0116556 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0114556 |
| LYZ | lysozyme | 0.0112524 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.011002 |
| C7 | complement component 7 | 0.0108328 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0106769 |
| COL5A2 | collagen, type V, alpha 2 | 0.0104101 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0102228 |
| CADM1 | cell adhesion molecule 1 | 0.00994935 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00979452 |
| DAPK1 | death-associated protein kinase 1 | 0.00975389 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.00974415 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0096696 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00951004 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.0094535 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00926775 |
| PRDX2 | peroxiredoxin 2 | 0.00923644 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00917332 |
| MMD | monocyte to macrophage differentiation-associated | 0.00916992 |
| NID1 | nidogen 1 | 0.00901362 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00895554 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00889841 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00885417 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00881502 |
| CFI | complement factor I | 0.00880044 |
| MECOM | MDS1 and EVI1 complex locus | 0.00868818 |
| XPO7 | exportin 7 | 0.00860418 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00857643 |
| TFDP1 | transcription factor Dp-1 | 0.00855637 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.00832817 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00827891 |
| PTCH1 | patched 1 | 0.0082603 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.00820698 |
| CFD | complement factor D (adipsin) | 0.00820482 |
| HEATR1 | HEAT repeat containing 1 | 0.0081758 |
| ANXA5 | annexin A5 | 0.00814576 |
| TSPAN13 | tetraspanin 13 | 0.00810161 |
| TNS3 | tensin 3 | 0.00808104 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | 0.00806194 |
| HELLS | helicase, lymphoid-specific | 0.00794778 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 0.00794254 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0079107 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00780149 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00780099 |
| MSLN | mesothelin | 0.00775686 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00775437 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00774552 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00773717 |
| HOXB7 | homeobox B7 | 0.007735 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.0077104 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00762846 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00755639 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0075546 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.00752857 |
| SNX11 | sorting nexin 11 | 0.00751974 |
| COQ8A | coenzyme Q8A | 0.00748872 |
| SEPTIN10 | septin 10 | 0.00747972 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00746465 |
| FOXF1 | forkhead box F1 | 0.00743498 |
| GPATCH8 | G patch domain containing 8 | 0.00739596 |
| MDFIC | MyoD family inhibitor domain containing | 0.00736242 |
| RGS5 | regulator of G-protein signaling 5 | 0.00732665 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 0.00729655 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.0072902 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.00727417 |
| VDAC1 | voltage-dependent anion channel 1 | 0.00725885 |
| SFTPC | surfactant protein C | 0.00723427 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.00721057 |
| CYRIA | CYFIP related Rac1 interactor A | 0.00719197 |
| CST3 | cystatin C | 0.00718136 |
| FSTL1 | follistatin-like 1 | 0.00716446 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.00713366 |
| RNF38 | ring finger protein 38 | 0.00703157 |
| SLC9A6 | solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 | 0.00703048 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.00702204 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.00699263 |
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.00698211 |
| ECM1 | extracellular matrix protein 1 | 0.00696014 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.00694066 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00693916 |
| PLTP | phospholipid transfer protein | 0.00692118 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00691834 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00690849 |
| SLC43A3 | solute carrier family 43, member 3 | 0.00686862 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00684992 |
| DCHS1 | dachsous cadherin-related 1 | 0.00682771 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.00681847 |
| BEX1 | brain expressed, X-linked 1 | 0.00681367 |
| TMSB15A | thymosin beta 15a | 0.00680737 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00676721 |
| ADCY3 | adenylate cyclase 3 | 0.00673226 |
| INSIG1 | insulin induced gene 1 | 0.00672103 |
| CLIC5 | chloride intracellular channel 5 | 0.00671914 |
| ADIRF | adipogenesis regulatory factor | 0.00670589 |
| HOXB6 | homeobox B6 | 0.0066919 |
| GOLM1 | golgi membrane protein 1 | 0.00668792 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.0066613 |
| G0S2 | G0/G1 switch 2 | 0.00663846 |
| HYOU1 | hypoxia up-regulated 1 | 0.00658165 |
| CD99 | CD99 molecule | 0.00656099 |
| IFI44L | interferon-induced protein 44-like | 0.00652713 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00652408 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00652286 |
| MPZL2 | myelin protein zero-like 2 | 0.00651384 |
| TSPAN8 | tetraspanin 8 | 0.00651083 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0064719 |
| GRB14 | growth factor receptor-bound protein 14 | 0.00647085 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00641521 |
| KIF14 | kinesin family member 14 | 0.00641202 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00638169 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0063766 |
| GPM6B | glycoprotein M6B | 0.00637175 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00635027 |
| CD93 | CD93 molecule | 0.00632567 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00631557 |
| LRRC17 | leucine rich repeat containing 17 | 0.00631541 |
| PDZD2 | PDZ domain containing 2 | 0.00629939 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00628189 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00627727 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 0.0062572 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00625033 |
| PALMD | palmdelphin | 0.00624409 |
| TMEM176B | transmembrane protein 176B | 0.00624192 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.00623197 |
| ASPH | aspartate beta-hydroxylase | 0.00620761 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.00619205 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.00618955 |
| CIT | citron rho-interacting serine/threonine kinase | 0.00618605 |
| DMD | dystrophin | 0.00616954 |
| FZD6 | frizzled class receptor 6 | 0.00615396 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00615194 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.00614286 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.00613899 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00613229 |
| LDB2 | LIM domain binding 2 | 0.00612295 |
| SMC2 | structural maintenance of chromosomes 2 | 0.00611534 |
| FANCL | Fanconi anemia, complementation group L | 0.00611123 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.00609958 |
| NPY | neuropeptide Y | 0.00608142 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 | 0.00608051 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.00607013 |
| EXO1 | exonuclease 1 | 0.00606625 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.00606447 |
| C2CD5 | C2 calcium-dependent domain containing 5 | 0.00605835 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0060567 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0060557 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | 0.00603193 |
| CANX | calnexin | 0.00602007 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.00601986 |
| FADS1 | fatty acid desaturase 1 | 0.00600958 |
| PLK1 | polo-like kinase 1 | 0.00600706 |
| MEN1 | multiple endocrine neoplasia I | 0.00599836 |
| GRHPR | glyoxylate reductase/hydroxypyruvate reductase | 0.00599746 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00599613 |
| TLR2 | toll-like receptor 2 | 0.00599258 |
| TNS1 | tensin 1 | 0.00597901 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00596158 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.00595976 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 | 0.00594992 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00594888 |
| IFI44 | interferon-induced protein 44 | 0.00593326 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00589594 |
| NELL1 | NEL-like 1 (chicken) | 0.00589113 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00588573 |
| CD163 | CD163 molecule | 0.00588106 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00587668 |
| MERTK | MER proto-oncogene, tyrosine kinase | 0.0058678 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00586714 |
| RASA4 | RAS p21 protein activator 4 | 0.00586263 |
| PRSS3 | protease, serine, 3 | 0.00586135 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.00586025 |
| QKI | QKI, KH domain containing, RNA binding | 0.00585621 |
| CTSE | cathepsin E | 0.005855 |
| NDNF | neuron-derived neurotrophic factor | 0.00584837 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.0058337 |
| CD302 | CD302 molecule | 0.00582719 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.00582241 |
| NEMP1 | nuclear envelope integral membrane protein 1 | 0.00581545 |
| PLS3 | plastin 3 | 0.00580648 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00580645 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00580166 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00579388 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00577906 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.00577667 |
| CDK2 | cyclin-dependent kinase 2 | 0.00576402 |
| PCDH9 | protocadherin 9 | 0.00575261 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.00574711 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.00574584 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.0057382 |
| A2M | alpha-2-macroglobulin | 0.00573544 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00571849 |
| RAB20 | RAB20, member RAS oncogene family | 0.00570932 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) | 0.0057014 |
| NINL | ninein-like | 0.00569946 |
| CDCA4 | cell division cycle associated 4 | 0.00569752 |
| CDC45 | cell division cycle 45 | 0.00567065 |
| MARCO | macrophage receptor with collagenous structure | 0.00566706 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.00566082 |
| DHFR | dihydrofolate reductase | 0.0056551 |
| FASN | fatty acid synthase | 0.0056529 |
| NLGN4X | neuroligin 4, X-linked | 0.00564726 |
| HSPA13 | heat shock protein 70kDa family, member 13 | 0.00564607 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0056429 |
| RDX | radixin | 0.00563362 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00563243 |
| MX1 | MX dynamin-like GTPase 1 | 0.00562459 |
| ACTB | actin, beta | 0.0056234 |
| PTK2 | protein tyrosine kinase 2 | 0.00561835 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0056175 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00560444 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.0055965 |
| SEPTIN2 | septin 2 | 0.00558272 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00557144 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00556486 |
| KIF11 | kinesin family member 11 | 0.00554012 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.00552512 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0055175 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.00551423 |
| CBX1 | chromobox homolog 1 | 0.0054942 |
| BRCA1 | breast cancer 1, early onset | 0.0054841 |
| KIF18B | kinesin family member 18B | 0.00548053 |
| GAA | glucosidase, alpha; acid | 0.00547794 |
| SRPRA | SRP receptor subunit alpha | 0.00545878 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0054545 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00544532 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.00543337 |
| TIMELESS | timeless circadian clock | 0.0054307 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00541272 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.00539777 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00539718 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.00539632 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.00539157 |
| COLEC12 | collectin sub-family member 12 | 0.00538961 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | 0.00538226 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 0.005376 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0053535 |
| FTO | fat mass and obesity associated | 0.00534458 |
| ISOC1 | isochorismatase domain containing 1 | 0.00533701 |
| RNASET2 | ribonuclease T2 | 0.00533125 |
| INSR | insulin receptor | 0.00532826 |
| ZNF589 | zinc finger protein 589 | 0.00531118 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00529913 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00529779 |
| PUM2 | pumilio RNA-binding family member 2 | 0.00528776 |
| SRP9 | signal recognition particle 9kDa | 0.00527679 |
| AURKB | aurora kinase B | 0.00527384 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 0.0052659 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.00526396 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.00526006 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | -0.0145318 |
| KRT7 | keratin 7, type II | -0.0129112 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.0126555 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.0125076 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -0.0123821 |
| DSP | desmoplakin | -0.0121273 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0118404 |
| PEG10 | paternally expressed 10 | -0.0118173 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.011558 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.0115028 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.011438 |
| LTF | lactotransferrin | -0.0113024 |
| ZIC1 | Zic family member 1 | -0.0111885 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.0108649 |
| H1-2 | H1.2 linker histone, cluster member | -0.0107946 |
| POSTN | periostin, osteoblast specific factor | -0.0107845 |
| CRYAB | crystallin, alpha B | -0.0102781 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00994603 |
| CTSD | cathepsin D | -0.00992374 |
| MSMB | microseminoprotein, beta- | -0.00965543 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0096175 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00934117 |
| PROM1 | prominin 1 | -0.00915197 |
| IPO13 | importin 13 | -0.00910644 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | -0.00904433 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00896016 |
| PLK2 | polo-like kinase 2 | -0.00888511 |
| KLHL24 | kelch-like family member 24 | -0.00887 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | -0.00884416 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00878111 |
| EFHD1 | EF-hand domain family, member D1 | -0.00876639 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.0086702 |
| DIPK1A | divergent protein kinase domain 1A | -0.00851182 |
| CD58 | CD58 molecule | -0.0085068 |
| WASL | Wiskott-Aldrich syndrome-like | -0.00846844 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00843085 |
| HOXC10 | homeobox C10 | -0.00823887 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00814802 |
| TOX3 | TOX high mobility group box family member 3 | -0.00812052 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00806501 |
| NVL | nuclear VCP-like | -0.00793801 |
| CLDN4 | claudin 4 | -0.00788373 |
| ZNF91 | zinc finger protein 91 | -0.00787686 |
| IER5 | immediate early response 5 | -0.00784026 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -0.00779703 |
| RGCC | regulator of cell cycle | -0.00772414 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00760135 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00759816 |
| ZC3H12A | zinc finger CCCH-type containing 12A | -0.00758682 |
| PYCARD | PYD and CARD domain containing | -0.00757526 |
| DUSP10 | dual specificity phosphatase 10 | -0.00754895 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00754333 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.00752561 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00748309 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00748268 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -0.00742314 |
| PIP | prolactin-induced protein | -0.0072934 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0072906 |
| EMX2 | empty spiracles homeobox 2 | -0.00725751 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00725123 |
| DCLK1 | doublecortin-like kinase 1 | -0.00725058 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00724961 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.0071769 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0071679 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00715875 |
| CFB | complement factor B | -0.00710506 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00706959 |
| MYLIP | myosin regulatory light chain interacting protein | -0.00700061 |
| ZNF277 | zinc finger protein 277 | -0.0069854 |
| APOD | apolipoprotein D | -0.00698076 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 | -0.00695525 |
| MAP7 | microtubule-associated protein 7 | -0.00692863 |
| CLDN7 | claudin 7 | -0.00685316 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00685192 |
| WTAP | Wilms tumor 1 associated protein | -0.00684632 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00683575 |
| SIX2 | SIX homeobox 2 | -0.00682579 |
| CSTA | cystatin A (stefin A) | -0.00677216 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | -0.00676064 |
| VASP | vasodilator-stimulated phosphoprotein | -0.00674699 |
| KRT15 | keratin 15, type I | -0.00674543 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00673588 |
| KRT19 | keratin 19, type I | -0.00673488 |
| HDAC9 | histone deacetylase 9 | -0.00668646 |
| GPER1 | G protein-coupled estrogen receptor 1 | -0.00664923 |
| ZNF331 | zinc finger protein 331 | -0.00664627 |
| JUNB | jun B proto-oncogene | -0.00661625 |
| SGCE | sarcoglycan, epsilon | -0.00660946 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 | -0.00657 |
| ARL4A | ADP-ribosylation factor-like 4A | -0.00654882 |
| CLDN8 | claudin 8 | -0.00653528 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | -0.00653434 |
| KRT14 | keratin 14, type I | -0.00652842 |
| OAT | ornithine aminotransferase | -0.00650081 |
| DUSP2 | dual specificity phosphatase 2 | -0.00646772 |
| SNAI2 | snail family zinc finger 2 | -0.00644793 |
| CDC42 | cell division cycle 42 | -0.00642866 |
| BEX4 | brain expressed, X-linked 4 | -0.0064225 |
| MLF1 | myeloid leukemia factor 1 | -0.00638961 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00637755 |
| RGS16 | regulator of G-protein signaling 16 | -0.00637538 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0063626 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00631116 |
| ITM2A | integral membrane protein 2A | -0.00626854 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.00626218 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00625334 |
| GOLT1B | golgi transport 1B | -0.00620291 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00619481 |
| FGB | fibrinogen beta chain | -0.00617768 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00616991 |
| RRAGC | Ras-related GTP binding C | -0.00614834 |
| ODC1 | ornithine decarboxylase 1 | -0.00611429 |
| FAM117A | family with sequence similarity 117, member A | -0.00610353 |
| GYG1 | glycogenin 1 | -0.00607679 |
| AGO3 | argonaute RISC catalytic component 3 | -0.00607082 |
| ENOPH1 | enolase-phosphatase 1 | -0.00606853 |
| ACAP1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 | -0.0060223 |
| KRT17 | keratin 17, type I | -0.00601386 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.00597405 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00596709 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.0059174 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00591522 |
| EHF | ets homologous factor | -0.00588218 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00588076 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00583882 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00580674 |
| TRIB2 | tribbles pseudokinase 2 | -0.00580375 |
| STK26 | serine/threonine protein kinase 26 | -0.0057703 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00576501 |
| PMP22 | peripheral myelin protein 22 | -0.00576283 |
| MAB21L1 | mab-21-like 1 (C. elegans) | -0.0057411 |
| LYRM4 | LYR motif containing 4 | -0.00573922 |
| RORA | RAR-related orphan receptor A | -0.00572461 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00569385 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.00569279 |
| CD7 | CD7 molecule | -0.0056687 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0056637 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -0.00565211 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00564718 |
| S100A9 | S100 calcium binding protein A9 | -0.00564353 |
| S100A14 | S100 calcium binding protein A14 | -0.00563742 |
| CST6 | cystatin E/M | -0.0056264 |
| EPCAM | epithelial cell adhesion molecule | -0.00561708 |
| HMOX1 | heme oxygenase 1 | -0.00561568 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00558478 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00556932 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00556812 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00554446 |
| MMP7 | matrix metallopeptidase 7 | -0.00553552 |
| SPART | spartin | -0.00553147 |
| FCGBP | Fc fragment of IgG binding protein | -0.00552792 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0055215 |
| SRPK2 | SRSF protein kinase 2 | -0.0055169 |
| KRT23 | keratin 23, type I | -0.00550049 |
| XIC | X chromosome inactivation center | -0.00548952 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00548452 |
| CA12 | carbonic anhydrase XII | -0.00546641 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00546506 |
| RNF167 | ring finger protein 167 | -0.0054498 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | -0.00543616 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00543425 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00540815 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.00539097 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.00538235 |
| HTRA1 | HtrA serine peptidase 1 | -0.00537028 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.00534351 |
| SIKE1 | suppressor of IKBKE 1 | -0.00534304 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing | -0.00533606 |
| DUSP14 | dual specificity phosphatase 14 | -0.00533196 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00533102 |
| PRSS23 | protease, serine, 23 | -0.00532242 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00530194 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00529697 |
| EVI2A | ecotropic viral integration site 2A | -0.00528767 |
| CLDN3 | claudin 3 | -0.00528273 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.00526256 |
| LBH | limb bud and heart development | -0.00526233 |
| ATOX1 | antioxidant 1 copper chaperone | -0.00525551 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein | -0.00525106 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00524597 |
| TES | testin LIM domain protein | -0.00524338 |
| RRAGD | Ras-related GTP binding D | -0.00524177 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.00521075 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00518838 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.00516285 |
| MVP | major vault protein | -0.00509098 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00508731 |
| LSP1 | lymphocyte-specific protein 1 | -0.00508496 |
| ASS1 | argininosuccinate synthase 1 | -0.00508468 |
| OLFM4 | olfactomedin 4 | -0.00507443 |
| CYB5R1 | cytochrome b5 reductase 1 | -0.00506587 |
| MMP8 | matrix metallopeptidase 8 | -0.00505213 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | -0.00504304 |
| CD38 | CD38 molecule | -0.00500408 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00499593 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | -0.00498958 |
| BBC3 | BCL2 binding component 3 | -0.0049773 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.00497586 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -0.00497129 |
| GRB2 | growth factor receptor-bound protein 2 | -0.00496932 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.00496808 |
| RTN2 | reticulon 2 | -0.00496066 |
| CLCA4 | chloride channel accessory 4 | -0.00495954 |
| PHYH | phytanoyl-CoA 2-hydroxylase | -0.0049528 |
| HPGDS | hematopoietic prostaglandin D synthase | -0.00494993 |
| NPC2 | Niemann-Pick disease, type C2 | -0.00494214 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00493789 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | -0.0049352 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00493382 |
| GSR | glutathione reductase | -0.00492943 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00491758 |
| TRIP6 | thyroid hormone receptor interactor 6 | -0.00490719 |
| PXDC1 | PX domain containing 1 | -0.00488479 |
| CAPN1 | calpain 1, (mu/I) large subunit | -0.00488105 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00488042 |
| LOC283683 | uncharacterized LOC283683 | -0.00483091 |
| MFAP5 | microfibrillar associated protein 5 | -0.00483036 |
| CA8 | carbonic anhydrase VIII | -0.0048283 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -0.00482048 |
| H1-4 | H1.4 linker histone, cluster member | -0.00481242 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00481179 |
| EN1 | engrailed homeobox 1 | -0.00480331 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00479864 |
| IRF1 | interferon regulatory factor 1 | -0.00479197 |
| NFIL3 | nuclear factor, interleukin 3 regulated | -0.00477419 |
| FAM110B | family with sequence similarity 110, member B | -0.00477075 |
| WDR41 | WD repeat domain 41 | -0.00475844 |
| CLCA1 | chloride channel accessory 1 | -0.0047522 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00474448 |
| TGFA | transforming growth factor, alpha | -0.0047405 |
| HIST1H2BD | histone cluster 1, H2bd | -0.0047364 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.00473461 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00473207 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00473038 |
| CLGN | calmegin | -0.00472028 |
| PXN | paxillin | -0.00471245 |
| SF3B5 | splicing factor 3b, subunit 5, 10kDa | -0.00470807 |
| ETHE1 | ethylmalonic encephalopathy 1 | -0.00469683 |
| STAMBP | STAM binding protein | -0.00469092 |
| MAMLD1 | mastermind-like domain containing 1 | -0.0046707 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0046631 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00465765 |
| ANKRD36 | ankyrin repeat domain 36 | -0.00465344 |
| CRYM | crystallin, mu | -0.0046421 |
| BRD2 | bromodomain containing 2 | -0.00463178 |
| DGKZ | diacylglycerol kinase, zeta | -0.00462996 |
| CLCA2 | chloride channel accessory 2 | -0.00461787 |
| CERT1 | ceramide transporter 1 | -0.00461473 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00460813 |
