SH2D2A Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description SH2 domain containing 2A|This gene encodes an adaptor protein thought to function in T-cell signal transduction. A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] (NCBI Entrez Gene Database, 9047)
External Link https://ncbi.nlm.nih.gov/gene/9047
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Genes

500 genes differentially expressed following the SH2D2A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ZDHHC6 zinc finger, DHHC-type containing 6 0.0146697
TM9SF3 transmembrane 9 superfamily member 3 0.0135176
MYOF myoferlin 0.0123602
CST7 cystatin F (leukocystatin) 0.0123068
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.0111149
PRKCH protein kinase C, eta 0.0109003
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0108974
CEMIP cell migration inducing protein, hyaluronan binding 0.0108757
PGAM1 phosphoglycerate mutase 1 (brain) 0.0107728
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0107314
ANXA1 annexin A1 0.0106952
CXCL10 chemokine (C-X-C motif) ligand 10 0.0106308
TPM4 tropomyosin 4 0.0105422
CXADR coxsackie virus and adenovirus receptor 0.010496
MET MET proto-oncogene, receptor tyrosine kinase 0.00997951
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.00996502
BIK BCL2-interacting killer (apoptosis-inducing) 0.00992221
NDRG1 N-myc downstream regulated 1 0.00990296
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00989592
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.00952508
REEP5 receptor accessory protein 5 0.00944861
PEA15 phosphoprotein enriched in astrocytes 15 0.00930746
ETNPPL ethanolamine-phosphate phospho-lyase 0.00922314
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00920926
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.00919369
HIST1H2BD histone cluster 1, H2bd 0.00916156
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00915321
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.00914658
EMX2 empty spiracles homeobox 2 0.0091162
CARMIL1 capping protein regulator and myosin 1 linker 1 0.00909895
VEGFA vascular endothelial growth factor A 0.00899394
HOXB7 homeobox B7 0.00897144
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00896977
AUTS2 autism susceptibility candidate 2 0.00895159
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.00876894
MXI1 MAX interactor 1, dimerization protein 0.00866495
KYNU kynureninase 0.00865508
DAZAP2 DAZ associated protein 2 0.00859142
CNOT4 CCR4-NOT transcription complex, subunit 4 0.0085491
TARS1 threonyl-tRNA synthetase 1 0.0084172
BHMT betaine--homocysteine S-methyltransferase 0.00840289
GCLC glutamate-cysteine ligase, catalytic subunit 0.0082976
TMPRSS4 transmembrane protease, serine 4 0.00826739
KRT6A keratin 6A, type II 0.00821824
PRSS21 protease, serine, 21 (testisin) 0.00820861
SPRR3 small proline-rich protein 3 0.00819602
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.00816778
CXCL9 chemokine (C-X-C motif) ligand 9 0.00816148
SET SET nuclear proto-oncogene 0.00816056
CD69 CD69 molecule 0.00814716
FOLR1 folate receptor 1 (adult) 0.0081459
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00813837
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00806053
CA2 carbonic anhydrase II 0.00801722
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00801336
SLC38A2 solute carrier family 38, member 2 0.00800929
PRF1 perforin 1 (pore forming protein) 0.00792713
GDI2 GDP dissociation inhibitor 2 0.00787605
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00787153
CTSB cathepsin B 0.00778539
PRKCQ protein kinase C, theta 0.00777297
DUSP10 dual specificity phosphatase 10 0.00768971
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.00763616
PUF60 poly-U binding splicing factor 60KDa 0.00758926
CCNA2 cyclin A2 0.00758602
IL2RB interleukin 2 receptor, beta 0.00756469
PLEK2 pleckstrin 2 0.00754444
WAC WW domain containing adaptor with coiled-coil 0.0075232
CXCL8 chemokine (C-X-C motif) ligand 8 0.00751723
SGK1 serum/glucocorticoid regulated kinase 1 0.00750807
IL2RG interleukin 2 receptor, gamma 0.00750147
RIDA reactive intermediate imine deaminase A homolog 0.00748817
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00747816
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00747424
RND3 Rho family GTPase 3 0.00746417
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.00745884
C21ORF91 chromosome 21 open reading frame 91 0.00745197
TOX thymocyte selection-associated high mobility group box 0.0074434
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.0074318
HDAC9 histone deacetylase 9 0.007401
CD2 CD2 molecule 0.00739393
ABLIM1 actin binding LIM protein 1 0.00737085
NMD3 NMD3 ribosome export adaptor 0.00735491
ADAM10 ADAM metallopeptidase domain 10 0.0073022
SORD sorbitol dehydrogenase 0.00729914
RALB v-ral simian leukemia viral oncogene homolog B 0.00729031
GSR glutathione reductase 0.00727366
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.00724224
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00723344
ELL2 elongation factor, RNA polymerase II, 2 0.00723326
JUNB jun B proto-oncogene 0.00720959
CHMP5 charged multivesicular body protein 5 0.00720522
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.00717393
MPO myeloperoxidase 0.00713366
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.0071103
BPGM 2,3-bisphosphoglycerate mutase 0.00710862
LPXN leupaxin 0.00710793
FYB1 FYN binding protein 1 0.00709959
CTTN cortactin 0.00706857
SCGB2A1 secretoglobin, family 2A, member 1 0.00705953
MMP12 matrix metallopeptidase 12 0.00704918
SERINC1 serine incorporator 1 0.00701018
HSPE1 heat shock 10kDa protein 1 0.00700595
AGPS alkylglycerone phosphate synthase 0.00698531
PFKP phosphofructokinase, platelet 0.00695414
EXOC5 exocyst complex component 5 0.00693201
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00690747
UXT ubiquitously-expressed, prefoldin-like chaperone 0.00690707
GADD45B growth arrest and DNA-damage-inducible, beta 0.00690304
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.00690213
RAB32 RAB32, member RAS oncogene family 0.0068841
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00686492
PODXL podocalyxin-like 0.00684498
EPAS1 endothelial PAS domain protein 1 0.00684189
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00684184
CD58 CD58 molecule 0.00683078
ADM adrenomedullin 0.00682639
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00679463
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00677081
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.00675471
CTBP2 C-terminal binding protein 2 0.0067394
HSPA1A heat shock 70kDa protein 1A 0.0067252
UPK1B uroplakin 1B 0.00671124
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.00669447
KRT13 keratin 13, type I 0.0066807
PERP PERP, TP53 apoptosis effector 0.00667145
SNX11 sorting nexin 11 0.00667078
AIM2 absent in melanoma 2 0.00666439
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00665883
PRNP prion protein 0.00665832
CLEC2D C-type lectin domain family 2, member D 0.00665788
CLEC2B C-type lectin domain family 2, member B 0.00665677
GPR18 G protein-coupled receptor 18 0.00665059
COG7 component of oligomeric golgi complex 7 0.00663429
EGLN3 egl-9 family hypoxia-inducible factor 3 0.00661908
DCLRE1C DNA cross-link repair 1C 0.00659809
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.00659774
MED1 mediator complex subunit 1 0.00659589
AOC1 amine oxidase, copper containing 1 0.00656709
CXCL11 chemokine (C-X-C motif) ligand 11 0.00655573
ATF4 activating transcription factor 4 0.00655289
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa 0.00652582
MAP7 microtubule-associated protein 7 0.00652323
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.00651852
TGFBI transforming growth factor, beta-induced, 68kDa 0.00651417
ABHD17B abhydrolase domain containing 17B 0.00650219
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.0064729
GRAMD2B GRAM domain containing 2B 0.00646451
EVI2A ecotropic viral integration site 2A 0.0064548
PTK2 protein tyrosine kinase 2 0.00643783
YIPF5 Yip1 domain family, member 5 0.00641566
PARP8 poly (ADP-ribose) polymerase family, member 8 0.00641027
CANX calnexin 0.00640507
SLC35F2 solute carrier family 35, member F2 0.00640386
RHOB ras homolog family member B 0.00640166
STOM stomatin 0.00639812
PDCD6 programmed cell death 6 0.00639744
YME1L1 YME1-like 1 ATPase 0.00638396
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 0.00634582
TFRC transferrin receptor 0.00634048
GZMK granzyme K (granzyme 3; tryptase II) 0.00633851
TGIF1 TGFB-induced factor homeobox 1 0.00633253
MATR3 matrin 3 0.00633005
MCL1 myeloid cell leukemia 1 0.00632655
RCAN1 regulator of calcineurin 1 0.00632631
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00628487
CD27 CD27 molecule 0.00627526
C18ORF25 chromosome 18 open reading frame 25 0.00624883
DLG1 discs, large homolog 1 (Drosophila) 0.00622265
CD3D CD3d molecule, delta (CD3-TCR complex) 0.00620394
ZBTB35 zinc finger and BTB domain containing 35 0.00619235
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00614456
S100A2 S100 calcium binding protein A2 0.00614122
HSPA4 heat shock 70kDa protein 4 0.00613969
NFYA nuclear transcription factor Y, alpha 0.00612154
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.00611904
S100A11 S100 calcium binding protein A11 0.00610798
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 0.006103
ZFAND5 zinc finger, AN1-type domain 5 0.00609703
ZNF395 zinc finger protein 395 0.00609595
IRF1 interferon regulatory factor 1 0.0060957
EIF5 eukaryotic translation initiation factor 5 0.0060826
MAT2B methionine adenosyltransferase II, beta 0.00605846
OGA O-GlcNAcase 0.00605668
CD200 CD200 molecule 0.00604915
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.00602845
MID1IP1 MID1 interacting protein 1 0.00601967
YAP1 Yes-associated protein 1 0.00599554
CXCR4 chemokine (C-X-C motif) receptor 4 0.00598541
GLUD2 glutamate dehydrogenase 2 0.00598484
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.00597256
NFE2L2 nuclear factor, erythroid 2-like 2 0.00597182
ZBED2 zinc finger, BED-type containing 2 0.00596891
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.00596481
HMOX1 heme oxygenase 1 0.00596027
PDE4B phosphodiesterase 4B, cAMP-specific 0.00595946
IFNG interferon, gamma 0.00595504
RSRC2 arginine/serine-rich coiled-coil 2 0.00595185
SHTN1 shootin 1 0.00594973
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.00594953
ZBTB38 zinc finger and BTB domain containing 38 0.0059493
NKG7 natural killer cell granule protein 7 0.00594637
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 0.00592951
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.00591432
ZNF394 zinc finger protein 394 0.00590918
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.00589138
LASP1 LIM and SH3 protein 1 0.00587562
GSTP1 glutathione S-transferase pi 1 0.00586786
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.00585447
TRAM1 translocation associated membrane protein 1 0.00585239
SYT1 synaptotagmin I 0.00584963
RBM39 RNA binding motif protein 39 0.00583526
GNLY granulysin 0.00580085
CD8A CD8a molecule 0.00579902
TMEM176A transmembrane protein 176A 0.00578363
MNDA myeloid cell nuclear differentiation antigen 0.00577675
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 0.00576074
VLDLR very low density lipoprotein receptor 0.00575019
IGLL1 immunoglobulin lambda-like polypeptide 1 0.0057162
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.00571496
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00571283
TRIB2 tribbles pseudokinase 2 0.00571095
CSRP2 cysteine and glycine-rich protein 2 0.00570983
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.00570479
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) 0.00569328
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.00569136
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.00569011
HOXA1 homeobox A1 0.00567478
FOSL2 FOS-like antigen 2 0.00567281
ADAM28 ADAM metallopeptidase domain 28 0.00565563
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.00565172
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.00564901
PADI3 peptidyl arginine deiminase, type III 0.00564791
SLC25A46 solute carrier family 25, member 46 0.00564771
CTSW cathepsin W 0.00564215
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 0.00564132
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.00563193
CLDND1 claudin domain containing 1 0.005624
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.00560244
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.0055703
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.0055646
PREPL prolyl endopeptidase-like 0.00556216
RUNX3 runt-related transcription factor 3 0.00555068
TM2D1 TM2 domain containing 1 0.00554737
MARCHF5 membrane associated ring-CH-type finger 5 0.00554732
ZNF536 zinc finger protein 536 0.00554321
APOL1 apolipoprotein L, 1 0.00554264
CAPRIN1 cell cycle associated protein 1 0.00553168
LCK LCK proto-oncogene, Src family tyrosine kinase 0.00552416
MMP10 matrix metallopeptidase 10 0.00551457

decreased expression

Symbol Name Standardized Value
FABP4 fatty acid binding protein 4, adipocyte -0.0192293
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0153879
SRPX sushi-repeat containing protein, X-linked -0.0153168
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.0150635
MGP matrix Gla protein -0.014965
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0148687
TSPYL5 TSPY-like 5 -0.0147936
CHRDL1 chordin-like 1 -0.0147072
APOD apolipoprotein D -0.0145164
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0143179
MDK midkine (neurite growth-promoting factor 2) -0.013996
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -0.0130181
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0129522
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.0128692
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.0127177
THBS4 thrombospondin 4 -0.0125607
NPY1R neuropeptide Y receptor Y1 -0.0124364
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.0121716
PDGFRL platelet-derived growth factor receptor-like -0.0120047
DCN decorin -0.0119024
SYNM synemin, intermediate filament protein -0.0118461
CFD complement factor D (adipsin) -0.0117519
DLK1 delta-like 1 homolog (Drosophila) -0.0116536
G0S2 G0/G1 switch 2 -0.0116484
ADIPOQ adiponectin, C1Q and collagen domain containing -0.0116405
GAS1 growth arrest-specific 1 -0.0116363
GPX3 glutathione peroxidase 3 -0.0115757
SORBS1 sorbin and SH3 domain containing 1 -0.0114789
ISG15 ISG15 ubiquitin-like modifier -0.0113346
PLN phospholamban -0.01131
FADS1 fatty acid desaturase 1 -0.0112394
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.0110631
SPARCL1 SPARC-like 1 (hevin) -0.0108055
CD36 CD36 molecule (thrombospondin receptor) -0.0106725
SYNGR3 synaptogyrin 3 -0.0106634
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0104959
NDN necdin, melanoma antigen (MAGE) family member -0.0104254
FBLN1 fibulin 1 -0.0103579
POSTN periostin, osteoblast specific factor -0.0103042
TUBA1A tubulin, alpha 1a -0.0102569
GPC3 glypican 3 -0.0101883
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.00999907
TAGLN transgelin -0.00998053
FASN fatty acid synthase -0.00997945
DPT dermatopontin -0.00987811
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00987133
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -0.00984504
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00981578
DPYSL3 dihydropyrimidinase-like 3 -0.00976412
COL6A2 collagen, type VI, alpha 2 -0.00972803
ASPN asporin -0.00972482
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00969186
PLBD1 phospholipase B domain containing 1 -0.00961521
DES desmin -0.00956168
FN1 fibronectin 1 -0.00954935
FBLN2 fibulin 2 -0.00947375
NSDHL NAD(P) dependent steroid dehydrogenase-like -0.00943723
LTBP2 latent transforming growth factor beta binding protein 2 -0.00939312
PDLIM5 PDZ and LIM domain 5 -0.0093912
HOPX HOP homeobox -0.00927286
METTL7A methyltransferase like 7A -0.00914551
PDLIM3 PDZ and LIM domain 3 -0.00909867
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00906139
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00903462
ANPEP alanyl (membrane) aminopeptidase -0.00903318
MFAP5 microfibrillar associated protein 5 -0.0090286
SEPP1 selenoprotein P, plasma, 1 -0.00900862
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00899905
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00899905
ANO10 anoctamin 10 -0.00899838
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00896721
ZCCHC24 zinc finger, CCHC domain containing 24 -0.00893821
CDC20 cell division cycle 20 -0.00887787
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00884355
MFAP4 microfibrillar-associated protein 4 -0.00878088
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00877871
MCOLN1 mucolipin 1 -0.00877399
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00873813
IFITM1 interferon induced transmembrane protein 1 -0.00869383
COL14A1 collagen, type XIV, alpha 1 -0.00866013
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00865331
FRZB frizzled-related protein -0.00865035
GAL galanin/GMAP prepropeptide -0.00864218
TMSB15A thymosin beta 15a -0.00863646
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00863233
IGFBP5 insulin-like growth factor binding protein 5 -0.00856455
ZNF423 zinc finger protein 423 -0.00851749
GSTM3 glutathione S-transferase mu 3 (brain) -0.0084968
KLHL21 kelch-like family member 21 -0.00849288
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00845173
TMX4 thioredoxin-related transmembrane protein 4 -0.00837548
BAD BCL2-associated agonist of cell death -0.0083558
AOC3 amine oxidase, copper containing 3 -0.00834547
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00831228
CRIP2 cysteine-rich protein 2 -0.00825048
MYH11 myosin, heavy chain 11, smooth muscle -0.00824002
FGFR1 fibroblast growth factor receptor 1 -0.00819489
HMGB3 high mobility group box 3 -0.00813225
NXN nucleoredoxin -0.00810847
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00810735
TNNI2 troponin I type 2 (skeletal, fast) -0.00808919
ACTA1 actin, alpha 1, skeletal muscle -0.00807547
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00806334
ARMCX1 armadillo repeat containing, X-linked 1 -0.00801489
IFI6 interferon, alpha-inducible protein 6 -0.00798481
DBN1 drebrin 1 -0.00797447
TM7SF2 transmembrane 7 superfamily member 2 -0.00795705
PLAT plasminogen activator, tissue -0.00795136
NID1 nidogen 1 -0.00794451
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.0079053
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00789893
SMTN smoothelin -0.00789479
SLIT2 slit homolog 2 (Drosophila) -0.00789175
FHL1 four and a half LIM domains 1 -0.00783719
PLIN1 perilipin 1 -0.00783531
KLHL41 kelch-like family member 41 -0.00782495
LRRC17 leucine rich repeat containing 17 -0.00781974
SUB1 SUB1 homolog (S. cerevisiae) -0.00780431
ANXA6 annexin A6 -0.00779277
LTBP4 latent transforming growth factor beta binding protein 4 -0.007791
MX1 MX dynamin-like GTPase 1 -0.00777921
FKBP1B FK506 binding protein 1B, 12.6 kDa -0.00775225
TIMP4 TIMP metallopeptidase inhibitor 4 -0.00774889
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00772739
CLGN calmegin -0.00769227
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00761349
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00759922
KANK2 KN motif and ankyrin repeat domains 2 -0.00758166
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.0075174
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -0.00750753
NIBAN1 niban apoptosis regulator 1 -0.00744861
OBSL1 obscurin-like 1 -0.00744479
NPTX2 neuronal pentraxin II -0.00743272
GLS glutaminase -0.00741607
RHOD ras homolog family member D -0.00741571
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.00736953
NFIB nuclear factor I/B -0.00736225
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00736199
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00732008
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00731549
ICAM2 intercellular adhesion molecule 2 -0.007311
PEG10 paternally expressed 10 -0.00730923
MAMLD1 mastermind-like domain containing 1 -0.00730286
AKAP12 A kinase (PRKA) anchor protein 12 -0.00728378
DHCR24 24-dehydrocholesterol reductase -0.00728357
TWIST1 twist family bHLH transcription factor 1 -0.00728135
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0072748
SFRP1 secreted frizzled-related protein 1 -0.00727029
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.00726615
CLEC3B C-type lectin domain family 3, member B -0.00725603
COL3A1 collagen, type III, alpha 1 -0.00724367
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00724049
SPON2 spondin 2, extracellular matrix protein -0.00723114
STK39 serine threonine kinase 39 -0.00720792
SIDT2 SID1 transmembrane family, member 2 -0.00719146
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00716696
RTN2 reticulon 2 -0.00714603
EMP2 epithelial membrane protein 2 -0.00713916
MB myoglobin -0.00710644
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -0.00708704
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00708528
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.00707082
AQP1 aquaporin 1 (Colton blood group) -0.00705364
COL9A3 collagen, type IX, alpha 3 -0.00704987
ACTG2 actin, gamma 2, smooth muscle, enteric -0.0070142
COLEC12 collectin sub-family member 12 -0.00699145
LMOD1 leiomodin 1 (smooth muscle) -0.00697288
C1R complement component 1, r subcomponent -0.00695985
PXDN peroxidasin -0.00694108
AGR2 anterior gradient 2 -0.00693633
GLOD4 glyoxalase domain containing 4 -0.00691274
ADRA2A adrenoceptor alpha 2A -0.00689974
TNS1 tensin 1 -0.00689245
SOX11 SRY (sex determining region Y)-box 11 -0.00688526
FLNC filamin C, gamma -0.00687409
CCL21 chemokine (C-C motif) ligand 21 -0.00687204
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00684326
GLB1L2 galactosidase, beta 1-like 2 -0.00679587
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -0.00678752
EDNRA endothelin receptor type A -0.00678259
ARHGAP6 Rho GTPase activating protein 6 -0.00676956
WWTR1 WW domain containing transcription regulator 1 -0.0067625
SRM spermidine synthase -0.00676073
ACAT2 acetyl-CoA acetyltransferase 2 -0.00675949
MYO5C myosin VC -0.00670542
FXYD6 FXYD domain containing ion transport regulator 6 -0.0066832
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.00667024
PLK1 polo-like kinase 1 -0.00665945
CIDEA cell death-inducing DFFA-like effector a -0.00665658
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00665496
LEPR leptin receptor -0.00664607
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 -0.0066274
KLK5 kallikrein-related peptidase 5 -0.00662289
TSPAN13 tetraspanin 13 -0.00660188
SPINT1 serine peptidase inhibitor, Kunitz type 1 -0.00657944
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -0.00654005
DPYSL2 dihydropyrimidinase-like 2 -0.00653641
FCGRT Fc fragment of IgG, receptor, transporter, alpha -0.00650786
CKM creatine kinase, muscle -0.0065075
CIDEC cell death-inducing DFFA-like effector c -0.0065021
LST1 leukocyte specific transcript 1 -0.00650136
LPIN1 lipin 1 -0.00650013
MYH10 myosin, heavy chain 10, non-muscle -0.00649956
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 -0.00647897
MYLK myosin light chain kinase -0.00647521
PDZRN3 PDZ domain containing ring finger 3 -0.00645894
TEAD4 TEA domain family member 4 -0.00644804
TXNIP thioredoxin interacting protein -0.00644527
KLF11 Kruppel-like factor 11 -0.00644289
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -0.00643852
PENK proenkephalin -0.00643327
PRKCZ protein kinase C, zeta -0.00643227
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.00643127
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00642432
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00642066
SPAG16 sperm associated antigen 16 -0.00640095
NSG1 neuron specific gene family member 1 -0.00638432
NINL ninein-like -0.00635891
A2M alpha-2-macroglobulin -0.00635505
NOVA1 neuro-oncological ventral antigen 1 -0.00635394
IFITM2 interferon induced transmembrane protein 2 -0.006339
AMPD1 adenosine monophosphate deaminase 1 -0.00633815
FAM110B family with sequence similarity 110, member B -0.00633101
TRIM14 tripartite motif containing 14 -0.00632387
TECR trans-2,3-enoyl-CoA reductase -0.00631806
GUSB glucuronidase, beta -0.00631122
THOC6 THO complex 6 -0.00631069
ANGPTL2 angiopoietin-like 2 -0.00629053
GPD1L glycerol-3-phosphate dehydrogenase 1-like -0.00628425
OLFM4 olfactomedin 4 -0.00627329
ALOX5 arachidonate 5-lipoxygenase -0.00625807
F13A1 coagulation factor XIII, A1 polypeptide -0.00623947
COMP cartilage oligomeric matrix protein -0.00623405
EFNB2 ephrin-B2 -0.00623304
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -0.00622795
DCXR dicarbonyl/L-xylulose reductase -0.00620856
FST follistatin -0.00620447
EMILIN1 elastin microfibril interfacer 1 -0.00620274
ELOVL6 ELOVL fatty acid elongase 6 -0.00620028
TMEM45A transmembrane protein 45A -0.00619195
OGN osteoglycin -0.006185
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.0061727
NID2 nidogen 2 (osteonidogen) -0.00617092
LYZ lysozyme -0.0061641
DLG5 discs, large homolog 5 (Drosophila) -0.00615126
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 -0.00614546
CBR3 carbonyl reductase 3 -0.00613201
TACC3 transforming, acidic coiled-coil containing protein 3 -0.00613118
FBXO2 F-box protein 2 -0.00611726
MIA melanoma inhibitory activity -0.00608729