SH2D3A Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SH2 domain containing 3A| (NCBI Entrez Gene Database, 10045)
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Genes

351 genes differentially expressed following the SH2D3A gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
RNF227 ring finger protein 227 3.36544
NPSR1 neuropeptide S receptor 1 3.36544
EPHX4 epoxide hydrolase 4 3.36544
MSC musculin 3.36544
TMEM86B transmembrane protein 86B 3.36544
GFI1B growth factor independent 1B transcription repressor 3.36544
TF transferrin 3.36544
CORO6 coronin 6 3.36544
FAM216B family with sequence similarity 216, member B 3.36544
PTGFR prostaglandin F receptor (FP) 3.36544
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 3.36544
SPATA9 spermatogenesis associated 9 3.36544
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 3.36544
MAPK15 mitogen-activated protein kinase 15 3.36544
FGF4 fibroblast growth factor 4 3.36544
RBBP8NL RBBP8 N-terminal like 3.36544
IRF8 interferon regulatory factor 8 3.36544
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 3.36544
SMIM35 small integral membrane protein 35 3.36544
SLC46A2 solute carrier family 46, member 2 3.36544
JOSD2 Josephin domain containing 2 3.36544
CARMIL3 capping protein regulator and myosin 1 linker 3 3.36544
MAP3K7CL MAP3K7 C-terminal like 3.36544
ERVV-2 endogenous retrovirus group V, member 2 3.36544
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 3.36544
C1ORF141 chromosome 1 open reading frame 141 3.25159
MUC5B mucin 5B, oligomeric mucus/gel-forming 3.25159
BAAT bile acid CoA:amino acid N-acyltransferase 3.25159
ADAD2 adenosine deaminase domain containing 2 3.25159
TRIM15 tripartite motif containing 15 3.25159
PCDHB7 protocadherin beta 7 3.25159
NEUROD4 neuronal differentiation 4 3.25159
SLC35G6 solute carrier family 35, member G6 3.25159
DIRAS3 DIRAS family, GTP-binding RAS-like 3 3.25159
OR51D1 olfactory receptor, family 51, subfamily D, member 1 3.25159
GJB4 gap junction protein, beta 4, 30.3kDa 3.25159
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 3.25159
RNASE7 ribonuclease, RNase A family, 7 3.25159
CTDNEP1 CTD nuclear envelope phosphatase 1 3.25159
PRSS22 protease, serine, 22 3.25159
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 3.25159
NRSN1 neurensin 1 3.25159
OR5A1 olfactory receptor, family 5, subfamily A, member 1 3.25159
CD22 CD22 molecule 3.25159
NPC1L1 NPC1-like 1 3.25159
C8ORF74 chromosome 8 open reading frame 74 3.25159
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 3.25159
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 3.25159
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 3.25159
CX3CR1 chemokine (C-X3-C motif) receptor 1 3.25159
HBB hemoglobin, beta 3.25159
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) 3.25159
ASGR2 asialoglycoprotein receptor 2 3.25159
LOC105378220 macrophage receptor MARCO-like 3.25159
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 3.25159
ZNF804A zinc finger protein 804A 3.25159
SPINT4 serine peptidase inhibitor, Kunitz type 4 3.25159
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 3.25159
EPCIP exosomal polycystin 1 interacting protein 3.25159
XKR3 XK, Kell blood group complex subunit-related family, member 3 3.25159
VSIG8 V-set and immunoglobulin domain containing 8 3.25159
DYNLRB2 dynein, light chain, roadblock-type 2 3.25159
PXDC1 PX domain containing 1 3.25159
GDF6 growth differentiation factor 6 3.25159
TIMD4 T-cell immunoglobulin and mucin domain containing 4 3.25159
PTH parathyroid hormone 3.25159
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 3.25159
MS4A13 membrane-spanning 4-domains, subfamily A, member 13 3.25159
MIOX myo-inositol oxygenase 3.25159
NEURL3 neuralized E3 ubiquitin protein ligase 3 3.25159
DNAAF19 dynein axonemal assembly factor 19 3.25159
REELD1 reeler domain containing 1 3.25159
NHERF4 NHERF family PDZ scaffold protein 4 3.25159
INSYN1 inhibitory synaptic factor 1 3.25159
CBY2 chibby family member 2 3.25159
FYB1 FYN binding protein 1 3.25159
PTH1R parathyroid hormone 1 receptor 3.25159
ZAR1 zygote arrest 1 3.25159
STX11 syntaxin 11 3.25159
EXOC3L4 exocyst complex component 3-like 4 3.25159
NPFF neuropeptide FF-amide peptide precursor 3.25159
PTTG2 pituitary tumor-transforming 2 3.25159
PVRIG poliovirus receptor related immunoglobulin domain containing 3.25159
FAM3D family with sequence similarity 3, member D 3.25159
TBX20 T-box 20 3.25159
TMEM212 transmembrane protein 212 3.25159
CD274 CD274 molecule 3.25159
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 3.25159
PCDHB12 protocadherin beta 12 3.25159
IGFL2 IGF-like family member 2 3.25159
ACTL8 actin-like 8 3.25159
CDX2 caudal type homeobox 2 3.25159
OR2L2 olfactory receptor, family 2, subfamily L, member 2 3.25159
GLP2R glucagon-like peptide 2 receptor 3.25159
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4 3.25159
RNF113B ring finger protein 113B 3.25159
SCRT2 scratch family zinc finger 2 3.25159
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 3.25159
CCDC13 coiled-coil domain containing 13 3.25159
TUBA3E tubulin, alpha 3e 3.25159
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 3.25159
SPINK4 serine peptidase inhibitor, Kazal type 4 3.25159
GOLGA8K golgin A8 family, member K 3.25159
CLEC4D C-type lectin domain family 4, member D 3.25159
PAGE2 P antigen family, member 2 (prostate associated) 3.25159
NPFFR1 neuropeptide FF receptor 1 3.25159
WFDC6 WAP four-disulfide core domain 6 3.25159
DMRTB1 DMRT-like family B with proline-rich C-terminal, 1 3.25159
NXNL1 nucleoredoxin-like 1 3.25159
LRRC43 leucine rich repeat containing 43 3.25159
MAGEA2B melanoma antigen family A2B 3.25159
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta) 3.25159
ZNF366 zinc finger protein 366 3.25159
CABP7 calcium binding protein 7 3.25159
ZNF735 zinc finger protein 735 3.25159
SMIM22 small integral membrane protein 22 3.25159
TBPL2 TATA box binding protein like 2 3.25159
FCN3 ficolin (collagen/fibrinogen domain containing) 3 3.25159
GPR50 G protein-coupled receptor 50 3.25159
TSPAN32 tetraspanin 32 3.25159
MAB21L3 mab-21-like 3 (C. elegans) 3.25159
MAGEE2 melanoma antigen family E2 3.25159
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 3.25159
BHMT betaine--homocysteine S-methyltransferase 3.25159
GPR146 G protein-coupled receptor 146 3.25159
DCN decorin 3.25159
MOS v-mos Moloney murine sarcoma viral oncogene homolog 3.25159
CD28 CD28 molecule 3.25159
CTSE cathepsin E 3.25159
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 3.25159
C7ORF33 chromosome 7 open reading frame 33 3.25159
FGB fibrinogen beta chain 3.25159
SPEF1 sperm flagellar 1 3.25159
CCDC154 coiled-coil domain containing 154 3.25159
KLK2 kallikrein-related peptidase 2 3.25159
SLC31A2 solute carrier family 31 (copper transporter), member 2 3.25159
FBXO40 F-box protein 40 3.25159
EMILIN1 elastin microfibril interfacer 1 3.25159
RPS25 ribosomal protein S25 3.25159
C22ORF42 chromosome 22 open reading frame 42 3.25159
PRSS55 protease, serine, 55 3.25159
GLRA1 glycine receptor, alpha 1 3.25159
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21 3.25159
WFDC10A WAP four-disulfide core domain 10A 3.25159
HHIPL2 HHIP-like 2 3.25159
BIN2 bridging integrator 2 3.25159
PGM5 phosphoglucomutase 5 3.25159
AQP1 aquaporin 1 (Colton blood group) 3.25159
TRPM8 transient receptor potential cation channel, subfamily M, member 8 3.25159
PRAP1 proline-rich acidic protein 1 3.25159
ZPLD1 zona pellucida-like domain containing 1 3.25159
PADI4 peptidyl arginine deiminase, type IV 3.25159
GREM1 gremlin 1, DAN family BMP antagonist 3.25159
ADGRF5 adhesion G protein-coupled receptor F5 3.25159
MAEL maelstrom spermatogenic transposon silencer 3.25159
KIF4B kinesin family member 4B 3.25159
EPX eosinophil peroxidase 3.25159
ECM1 extracellular matrix protein 1 3.25159
DKK2 dickkopf WNT signaling pathway inhibitor 2 3.25159
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific 3.14133
SLC45A1 solute carrier family 45, member 1 3.12745
CCDC17 coiled-coil domain containing 17 3.04174
CA11 carbonic anhydrase XI 2.96485
ERFE erythroferrone 2.84702
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 2.75297
TIAM2 T-cell lymphoma invasion and metastasis 2 2.75297
DEXI Dexi homolog (mouse) 2.74097
TM7SF3 transmembrane 7 superfamily member 3 2.70952
DTNA dystrobrevin, alpha 2.64809
MORF4L1 mortality factor 4 like 1 2.62145
ZNF816 zinc finger protein 816 2.61576
LRRC8B leucine rich repeat containing 8 family, member B 2.60826
URI1 URI1, prefoldin-like chaperone 2.59022
ISYNA1 inositol-3-phosphate synthase 1 2.58766
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 2.55773
AJAP1 adherens junctions associated protein 1 2.55773
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 2.48612
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 2.48612
VRK3 vaccinia related kinase 3 2.4829
MPZL1 myelin protein zero-like 1 2.4829
OLFM2 olfactomedin 2 2.4829
SPX spexin hormone 2.43867
WNK4 WNK lysine deficient protein kinase 4 2.43867
ELOVL2 ELOVL fatty acid elongase 2 2.42143
EAF2 ELL associated factor 2 2.40708
PLAC1 placenta-specific 1 2.3976
SRSF5 serine/arginine-rich splicing factor 5 2.39352
SBK1 SH3 domain binding kinase 1 2.38669
MDM4 MDM4, p53 regulator 2.38067
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) 2.37765
KCNK12 potassium channel, two pore domain subfamily K, member 12 2.37162
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 2.36055
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 2.35716
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.35566
BRWD3 bromodomain and WD repeat domain containing 3 2.35405
EFR3B EFR3 homolog B (S. cerevisiae) 2.35056
CDCA4 cell division cycle associated 4 2.3281
ZNF33B zinc finger protein 33B 2.32506
NDFIP2 Nedd4 family interacting protein 2 2.32219
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 2.31876
OR52N2 olfactory receptor, family 52, subfamily N, member 2 2.31777
SP4 Sp4 transcription factor 2.28022
PON3 paraoxonase 3 2.27451
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 2.26318
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 2.2255
RNF217 ring finger protein 217 2.22351
TMEM250 transmembrane protein 250 2.22351
LRP3 low density lipoprotein receptor-related protein 3 2.17767
RFK riboflavin kinase 2.17679
TMEM26 transmembrane protein 26 2.17679
CMSS1 cms1 ribosomal small subunit homolog (yeast) 2.17356
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 2.17286
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 2.17286
CSTB cystatin B (stefin B) 2.17286
RASGRP4 RAS guanyl releasing protein 4 2.17286
SNAI2 snail family zinc finger 2 2.17286
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 2.17286
TNNI3K TNNI3 interacting kinase 2.17286
LAMP5 lysosomal-associated membrane protein family, member 5 2.17286
TMEM255A transmembrane protein 255A 2.17286
FAM167B family with sequence similarity 167, member B 2.17286
ILF2 interleukin enhancer binding factor 2 2.16487
ATP23 ATP23 metallopeptidase and ATP synthase assembly factor homolog 2.10486
PTPN23 protein tyrosine phosphatase, non-receptor type 23 2.10311
TGOLN2 trans-golgi network protein 2 2.09006
TUBB6 tubulin, beta 6 class V 2.08866
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 2.08625
NOL11 nucleolar protein 11 2.08174
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 2.06676
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 2.06353
STBD1 starch binding domain 1 2.0554
NPTXR neuronal pentraxin receptor 2.04096
PTGDR prostaglandin D2 receptor (DP) 2.03769
CLMN calmin (calponin-like, transmembrane) 2.00609
ATAD2B ATPase family, AAA domain containing 2B 2.00308
WNT5B wingless-type MMTV integration site family, member 5B 2.00192

decreased expression

Symbol Name Standardized Value
MOB3C MOB kinase activator 3C -3.36544
PCDHB3 protocadherin beta 3 -3.36544
CCDC157 coiled-coil domain containing 157 -3.36544
SCN7A sodium channel, voltage gated, type VII alpha subunit -3.36544
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F -3.36544
CCDC78 coiled-coil domain containing 78 -3.36544
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -3.36544
TAFA1 TAFA chemokine like family member 1 -3.36544
OLIG2 oligodendrocyte lineage transcription factor 2 -3.25159
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -3.25159
LATS1 large tumor suppressor kinase 1 -3.25159
NT5M 5',3'-nucleotidase, mitochondrial -3.25159
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -3.25159
ACRBP acrosin binding protein -3.25159
NRGN neurogranin (protein kinase C substrate, RC3) -3.25159
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) -3.25159
SMYD1 SET and MYND domain containing 1 -3.25159
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9 -3.25159
ZMYND12 zinc finger, MYND-type containing 12 -3.25159
PRSS53 protease, serine, 53 -3.25159
ABHD1 abhydrolase domain containing 1 -3.25159
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 -3.25159
AADACL3 arylacetamide deacetylase-like 3 -3.25159
ZNF285 zinc finger protein 285 -3.25159
MSMP microseminoprotein, prostate associated -3.25159
ASB5 ankyrin repeat and SOCS box containing 5 -3.25159
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -3.25159
RUNX3 runt-related transcription factor 3 -3.25159
ADAM12 ADAM metallopeptidase domain 12 -3.25159
FAM217A family with sequence similarity 217, member A -3.25159
CENATAC centrosomal AT-AC splicing factor -3.25159
FAM153A family with sequence similarity 153, member A -3.25159
WDR87 WD repeat domain 87 -3.25159
CCDC177 coiled-coil domain containing 177 -3.25159
DRD2 dopamine receptor D2 -3.25159
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 -3.25159
SCG2 secretogranin II -3.25159
ESPNL espin-like -3.25159
AK8 adenylate kinase 8 -3.24255
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa -3.19851
NPY5R neuropeptide Y receptor Y5 -3.14133
CCL28 chemokine (C-C motif) ligand 28 -3.13775
HYI hydroxypyruvate isomerase (putative) -3.00264
PHTF1 putative homeodomain transcription factor 1 -2.9011
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -2.82046
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 -2.81892
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 -2.80874
IFFO1 intermediate filament family orphan 1 -2.80601
HCK HCK proto-oncogene, Src family tyrosine kinase -2.7496
HEMK1 HemK methyltransferase family member 1 -2.74228
POT1 protection of telomeres 1 -2.74216
NIT1 nitrilase 1 -2.74097
PPP2R5D protein phosphatase 2, regulatory subunit B', delta -2.65687
SPARCL1 SPARC-like 1 (hevin) -2.64809
CAPN6 calpain 6 -2.64809
AGER advanced glycosylation end product-specific receptor -2.55773
LINC02762 long intergenic non-protein coding RNA 2762 -2.55773
BPTF bromodomain PHD finger transcription factor -2.55773
PLA2G10 phospholipase A2, group X -2.55773
MPZL2 myelin protein zero-like 2 -2.55773
CCDC172 coiled-coil domain containing 172 -2.54997
TMEM126A transmembrane protein 126A -2.5489
RNF32 ring finger protein 32 -2.54756
PRSS27 protease, serine 27 -2.50149
LIPT2-AS1 LIPT2 antisense RNA 1 -2.50149
TMOD1 tropomodulin 1 -2.50149
ARPC5L actin related protein 2/3 complex, subunit 5-like -2.46954
PIGG phosphatidylinositol glycan anchor biosynthesis, class G -2.41596
POLR2M polymerase (RNA) II (DNA directed) polypeptide M -2.37765
SYT1 synaptotagmin I -2.37162
MTLN mitoregulin -2.3716
PRMT7 protein arginine methyltransferase 7 -2.32219
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 -2.30477
FGF22 fibroblast growth factor 22 -2.28588
TBX6 T-box 6 -2.28588
LRTM1 leucine-rich repeats and transmembrane domains 1 -2.28588
SGMS1 sphingomyelin synthase 1 -2.28327
PTPN9 protein tyrosine phosphatase, non-receptor type 9 -2.28228
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) -2.2751
MCU mitochondrial calcium uniporter -2.26318
ANGPT1 angiopoietin 1 -2.25475
SHOX short stature homeobox -2.254
DDR2 discoidin domain receptor tyrosine kinase 2 -2.254
TENM3 teneurin transmembrane protein 3 -2.254
LIF leukemia inhibitory factor -2.254
UNC5D unc-5 homolog D (C. elegans) -2.25013
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) -2.23405
IQUB IQ motif and ubiquitin domain containing -2.21795
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 -2.21795
SMAD9 SMAD family member 9 -2.21795
PCDHB15 protocadherin beta 15 -2.21795
TSPAN7 tetraspanin 7 -2.21795
RBAK RB-associated KRAB zinc finger -2.20482
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -2.17954
ZNF649 zinc finger protein 649 -2.17286
JUP junction plakoglobin -2.1456
SPATC1L spermatogenesis and centriole associated 1-like -2.12469
USP21 ubiquitin specific peptidase 21 -2.1127
DOCK11 dedicator of cytokinesis 11 -2.1089
SOS2 son of sevenless homolog 2 (Drosophila) -2.10598
WDPCP WD repeat containing planar cell polarity effector -2.10598
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -2.10314
MRPS11 mitochondrial ribosomal protein S11 -2.08866
STK32C serine/threonine kinase 32C -2.06676
DAZL deleted in azoospermia-like -2.05883
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) -2.05746
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -2.05746
TMEM91 transmembrane protein 91 -2.05746
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -2.04096
RBM41 RNA binding motif protein 41 -2.04096
SLC38A7 solute carrier family 38, member 7 -2.04039
PICK1 protein interacting with PRKCA 1 -2.01545
IL18BP interleukin 18 binding protein -2.01388
GAS1 growth arrest-specific 1 -2.01388
YAF2 YY1 associated factor 2 -2.01388