SH3D21 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SH3 domain containing 21| (NCBI Entrez Gene Database, 79729)
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Genes

361 genes differentially expressed following the SH3D21 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
AQP4 aquaporin 4 3.00786
KLF9 Kruppel-like factor 9 3.00786
CLEC4G C-type lectin domain family 4, member G 3.00786
CD248 CD248 molecule, endosialin 3.00786
HUS1B HUS1 checkpoint homolog b (S. pombe) 3.00786
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) 3.00786
FAM90A1 family with sequence similarity 90, member A1 3.00786
ASB18 ankyrin repeat and SOCS box containing 18 3.00786
SLC26A3 solute carrier family 26 (anion exchanger), member 3 3.00786
BTNL9 butyrophilin-like 9 3.00786
SMYD1 SET and MYND domain containing 1 3.00786
TBPL2 TATA box binding protein like 2 3.00786
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 3.00786
CCL25 chemokine (C-C motif) ligand 25 3.00786
HHEX hematopoietically expressed homeobox 3.00786
IL17REL interleukin 17 receptor E-like 3.00786
MBOAT4 membrane bound O-acyltransferase domain containing 4 3.00786
STAB1 stabilin 1 3.00786
C8ORF48 chromosome 8 open reading frame 48 3.00786
DAO D-amino-acid oxidase 3.00786
TFEB transcription factor EB 3.00786
PRCD progressive rod-cone degeneration 3.00786
DENND6B DENN/MADD domain containing 6B 3.00786
FOXP3 forkhead box P3 3.00786
GSDMA gasdermin A 3.00786
CSNK2A3 casein kinase 2, alpha 3 polypeptide 3.00786
BMP5 bone morphogenetic protein 5 3.00786
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3.00786
GJC2 gap junction protein, gamma 2, 47kDa 3.00786
TSSK1B testis-specific serine kinase 1B 2.98034
CD34 CD34 molecule 2.98034
ACADL acyl-CoA dehydrogenase, long chain 2.98034
GJB3 gap junction protein, beta 3, 31kDa 2.98034
FXYD3 FXYD domain containing ion transport regulator 3 2.98034
ABRA actin binding Rho activating protein 2.98034
PEAR1 platelet endothelial aggregation receptor 1 2.98034
FOXA1 forkhead box A1 2.98034
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 2.98034
CELF6 CUGBP, Elav-like family member 6 2.98034
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.98034
GLUD2 glutamate dehydrogenase 2 2.98034
ALPK2 alpha-kinase 2 2.98034
CRYGC crystallin, gamma C 2.98034
VWC2L von Willebrand factor C domain containing protein 2-like 2.98034
SMCO3 single-pass membrane protein with coiled-coil domains 3 2.98034
EMCN endomucin 2.98034
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 2.98034
PRDM12 PR domain containing 12 2.98034
RGPD3 RANBP2-like and GRIP domain containing 3 2.98034
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 2.98034
OR13C3 olfactory receptor, family 13, subfamily C, member 3 2.98034
GUCY2F guanylate cyclase 2F, retinal 2.98034
PTGFR prostaglandin F receptor (FP) 2.98034
FAM221B family with sequence similarity 221, member B 2.98034
PRDM13 PR domain containing 13 2.98034
GPR20 G protein-coupled receptor 20 2.98034
TLX2 T-cell leukemia homeobox 2 2.98034
GALR3 galanin receptor 3 2.98034
C6ORF58 chromosome 6 open reading frame 58 2.98034
TAFA3 TAFA chemokine like family member 3 2.98034
CD22 CD22 molecule 2.98034
GSTM5 glutathione S-transferase mu 5 2.98034
LVRN laeverin 2.98034
BFSP2 beaded filament structural protein 2, phakinin 2.98034
LRTM3 leucine rich repeat transmembrane protein 3 2.98034
GPRASP3 G protein-coupled receptor associated sorting protein family member 3 2.98034
EIF2S3B eukaryotic translation initiation factor 2 subunit gamma B 2.98034
SPATS1 spermatogenesis associated, serine-rich 1 2.98034
PTH1R parathyroid hormone 1 receptor 2.98034
OTOA otoancorin 2.98034
AVPR1A arginine vasopressin receptor 1A 2.98034
LTB4R2 leukotriene B4 receptor 2 2.98034
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 2.98034
CXCL13 chemokine (C-X-C motif) ligand 13 2.98034
KRT81 keratin 81, type II 2.98034
ADRB1 adrenoceptor beta 1 2.98034
TRARG1 trafficking regulator of GLUT4 (SLC2A4) 1 2.98034
CIROP ciliated left-right organizer metallopeptidase 2.98034
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 2.98034
CATSPERH catsper channel auxiliary subunit eta 2.98034
SPMIP7 sperm microtubule inner protein 7 2.98034
CIMIP4 ciliary microtubule inner protein 4 2.98034
EPCIP exosomal polycystin 1 interacting protein 2.98034
CPNE8-AS1 CPNE8 antisense RNA 1 2.98034
C17ORF114 chromosome 17 open reading frame 114 2.98034
C8ORF90 chromosome 8 open reading frame 90 2.98034
CIBAR2 CBY1 interacting BAR domain containing 2 2.98034
STPG3 sperm-tail PG-rich repeat containing 3 2.98034
H2AC1 H2A clustered histone 1 2.98034
WDR64 WD repeat domain 64 2.98034
OSTN osteocrin 2.98034
ITK IL2-inducible T-cell kinase 2.98034
IRF5 interferon regulatory factor 5 2.98034
SCRG1 stimulator of chondrogenesis 1 2.98034
IL12RB1 interleukin 12 receptor, beta 1 2.98034
LBHD1 LBH domain containing 1 2.98034
ZNF98 zinc finger protein 98 2.98034
SIX6 SIX homeobox 6 2.98034
CFAP45 cilia and flagella associated protein 45 2.98034
RNF17 ring finger protein 17 2.98034
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 2.98034
ASB15 ankyrin repeat and SOCS box containing 15 2.98034
CHRD chordin 2.98034
PGC progastricsin (pepsinogen C) 2.98034
DYNAP dynactin associated protein 2.98034
NPIPB8 nuclear pore complex interacting protein family, member B8 2.98034
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B 2.98034
OOSP1 oocyte secreted protein 1, pseudogene 2.98034
PTH parathyroid hormone 2.98034
VCX3B variable charge, X-linked 3B 2.98034
CCR8 chemokine (C-C motif) receptor 8 2.98034
PIWIL3 piwi-like RNA-mediated gene silencing 3 2.98034
RASAL3 RAS protein activator like 3 2.98034
FAM186A family with sequence similarity 186, member A 2.98034
PRRT4 proline-rich transmembrane protein 4 2.98034
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 2.98034
LPA lipoprotein, Lp(a) 2.98034
LRRC46 leucine rich repeat containing 46 2.98034
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.98034
CPA2 carboxypeptidase A2 (pancreatic) 2.98034
MEFV Mediterranean fever 2.98034
APOC2 apolipoprotein C-II 2.98034
CLEC4C C-type lectin domain family 4, member C 2.98034
SNX31 sorting nexin 31 2.98034
POU2AF1 POU class 2 associating factor 1 2.98034
RANBP3L RAN binding protein 3-like 2.98034
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 2.98034
TTC9B tetratricopeptide repeat domain 9B 2.98034
HKDC1 hexokinase domain containing 1 2.98034
TMEM202 transmembrane protein 202 2.98034
CALHM3 calcium homeostasis modulator 3 2.98034
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 2.98034
EDN2 endothelin 2 2.98034
KLHL6 kelch-like family member 6 2.98034
DHH desert hedgehog 2.98034
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 2.98034
ANKRD60 ankyrin repeat domain 60 2.98034
KLF1 Kruppel-like factor 1 (erythroid) 2.98034
PRM1 protamine 1 2.98034
GOLGA6D golgin A6 family, member D 2.98034
ADAM2 ADAM metallopeptidase domain 2 2.98034
C2CD4B C2 calcium-dependent domain containing 4B 2.98034
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 2.98034
CLEC18C C-type lectin domain family 18, member C 2.98034
ORM2 orosomucoid 2 2.98034
ANKDD1B ankyrin repeat and death domain containing 1B 2.98034
LGALS14 lectin, galactoside-binding, soluble, 14 2.98034
SLC25A34 solute carrier family 25, member 34 2.98034
ERVV-1 endogenous retrovirus group V, member 1 2.98034
ABLIM3 actin binding LIM protein family, member 3 2.98034
KLHDC1 kelch domain containing 1 2.98034
IL27 interleukin 27 2.98034
CNR2 cannabinoid receptor 2 (macrophage) 2.98034
TMEM255A transmembrane protein 255A 2.98034
LEUTX leucine twenty homeobox 2.98034
RIBC1 RIB43A domain with coiled-coils 1 2.98034
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 2.98034
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 2.98034
KLK12 kallikrein-related peptidase 12 2.98034
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) 2.98034
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 2.98034
SLCO2B1 solute carrier organic anion transporter family, member 2B1 2.98034
SCNN1B sodium channel, non voltage gated 1 beta subunit 2.98034
GSTA2 glutathione S-transferase alpha 2 2.98034
NTN5 netrin 5 2.98034
PRTN3 proteinase 3 2.98034
PSG9 pregnancy specific beta-1-glycoprotein 9 2.98034
OR52N2 olfactory receptor, family 52, subfamily N, member 2 2.98034
FNDC8 fibronectin type III domain containing 8 2.98034
HEMGN hemogen 2.98034
AGR2 anterior gradient 2 2.98034
SLC7A4 solute carrier family 7, member 4 2.98034
TGM7 transglutaminase 7 2.98034
TMIGD3 transmembrane and immunoglobulin domain containing 3 2.98034
PRAM1 PML-RARA regulated adaptor molecule 1 2.98034
CCDC166 coiled-coil domain containing 166 2.98034
STMND1 stathmin domain containing 1 2.98034
SUN3 Sad1 and UNC84 domain containing 3 2.98034
EPO erythropoietin 2.98034
AOC1 amine oxidase, copper containing 1 2.98034
RERGL RERG/RAS-like 2.98034
TMEM156 transmembrane protein 156 2.98034
NUTM2D NUT family member 2D 2.98034
PLGLB1 plasminogen-like B1 2.98034
GREM1 gremlin 1, DAN family BMP antagonist 2.98034
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 2.98034
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 2.98034
DNAH8 dynein, axonemal, heavy chain 8 2.98034
USP17L7 ubiquitin specific peptidase 17-like family member 7 2.98034
CD80 CD80 molecule 2.98034
TAS2R42 taste receptor, type 2, member 42 2.98034
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) 2.98034
PGM5 phosphoglucomutase 5 2.98034
KIF4B kinesin family member 4B 2.98034
CD177 CD177 molecule 2.98034
GCM1 glial cells missing homolog 1 (Drosophila) 2.98034
PADI1 peptidyl arginine deiminase, type I 2.98034
CIB4 calcium and integrin binding family member 4 2.98034
CYBB cytochrome b-245, beta polypeptide 2.98034
KDM5A lysine (K)-specific demethylase 5A 2.94193
TSGA10IP testis specific, 10 interacting protein 2.92435
SCUBE2 signal peptide, CUB domain, EGF-like 2 2.92435
ACRBP acrosin binding protein 2.92435
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 2.89993
FLT1 fms-related tyrosine kinase 1 2.83708
NPTN neuroplastin 2.74029
USPL1 ubiquitin specific peptidase like 1 2.73359
TSGA10 testis specific, 10 2.71153
ZNF45 zinc finger protein 45 2.70913
RPL31 ribosomal protein L31 2.69384
PPIL4 peptidylprolyl isomerase (cyclophilin)-like 4 2.66975
C4ORF36 chromosome 4 open reading frame 36 2.64256
TTC23 tetratricopeptide repeat domain 23 2.58052
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 2.52609
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 2.51588
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 2.51137
SH3TC2 SH3 domain and tetratricopeptide repeats 2 2.50162
CATSPERD catsper channel auxiliary subunit delta 2.5012
GMNC geminin coiled-coil domain containing 2.5012
VPS26B vacuolar protein sorting 26 homolog B (S. pombe) 2.41315
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 2.3799
TMEM86B transmembrane protein 86B 2.37047
ATOH1 atonal homolog 1 (Drosophila) 2.36931
CCDC110 coiled-coil domain containing 110 2.28972
CRYBG1 crystallin beta-gamma domain containing 1 2.27455
OAZ1 ornithine decarboxylase antizyme 1 2.26499
ZNF614 zinc finger protein 614 2.26245
BZW2 basic leucine zipper and W2 domains 2 2.21153
CDR2L cerebellar degeneration-related protein 2-like 2.20991
DAPK3 death-associated protein kinase 3 2.20991
KANSL2 KAT8 regulatory NSL complex subunit 2 2.20863
ZNF91 zinc finger protein 91 2.20356
ZC3H13 zinc finger CCCH-type containing 13 2.19507
SCOC short coiled-coil protein 2.1727
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 2.16371
NFE2L1 nuclear factor, erythroid 2-like 1 2.16315
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3 2.15639
TMEM163 transmembrane protein 163 2.14906
MFSD2A major facilitator superfamily domain containing 2A 2.1391
HSPB8 heat shock 22kDa protein 8 2.13187
DPF1 D4, zinc and double PHD fingers family 1 2.08944
AHDC1 AT hook, DNA binding motif, containing 1 2.06127
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 2.0565
HIPK1 homeodomain interacting protein kinase 1 2.05148
TRMO tRNA methyltransferase O 2.05148
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 2.04335
MYH10 myosin, heavy chain 10, non-muscle 2.02889
B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 2.02826
SEPTIN8 septin 8 2.01831
KANSL1L KAT8 regulatory NSL complex subunit 1-like 2.01249
INSYN2A inhibitory synaptic factor 2A 2.00874
ANKIB1 ankyrin repeat and IBR domain containing 1 2.00325

decreased expression

Symbol Name Standardized Value
TTPAL tocopherol (alpha) transfer protein-like -3.00786
TRAM1L1 translocation associated membrane protein 1-like 1 -3.00786
ASPG asparaginase -3.00786
TRPV3 transient receptor potential cation channel, subfamily V, member 3 -3.00786
TNS2 tensin 2 -3.00786
TMEM272 transmembrane protein 272 -3.00786
RBM5 RNA binding motif protein 5 -2.98034
FAM120AOS family with sequence similarity 120A opposite strand -2.98034
PALM paralemmin -2.98034
CRAT carnitine O-acetyltransferase -2.98034
ACP5 acid phosphatase 5, tartrate resistant -2.98034
LEMD1 LEM domain containing 1 -2.98034
ADD1 adducin 1 (alpha) -2.98034
GCNA germ cell nuclear acidic peptidase -2.98034
USP8 ubiquitin specific peptidase 8 -2.98034
LGALSL lectin, galactoside-binding-like -2.98034
ARG1 arginase 1 -2.95339
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 -2.95339
PBOV1 prostate and breast cancer overexpressed 1 -2.95339
MYCT1 myc target 1 -2.95339
PLAAT2 phospholipase A and acyltransferase 2 -2.95339
KCNK15 potassium channel, two pore domain subfamily K, member 15 -2.95339
CLUL1 clusterin-like 1 (retinal) -2.95339
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 -2.95339
LKAAEAR1 LKAAEAR motif containing 1 -2.95339
OPRM1 opioid receptor, mu 1 -2.95339
ADCY4 adenylate cyclase 4 -2.95339
CD68 CD68 molecule -2.95339
EIF4E1B eukaryotic translation initiation factor 4E family member 1B -2.95339
AKAP3 A kinase (PRKA) anchor protein 3 -2.95339
CD160 CD160 molecule -2.95339
MSANTD1 Myb/SANT-like DNA-binding domain containing 1 -2.95339
BNC1 basonuclin 1 -2.95339
CALHM2 calcium homeostasis modulator 2 -2.95339
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 -2.95339
BTNL2 butyrophilin-like 2 -2.95339
CCDC92 coiled-coil domain containing 92 -2.95339
KISS1 KiSS-1 metastasis-suppressor -2.95339
RIPPLY2 ripply transcriptional repressor 2 -2.95339
PCDHB12 protocadherin beta 12 -2.95339
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 -2.95339
NXPH3 neurexophilin 3 -2.95339
APOB apolipoprotein B -2.95339
PWWP3B PWWP domain containing 3B -2.91955
ZSCAN16 zinc finger and SCAN domain containing 16 -2.91095
UQCRH ubiquinol-cytochrome c reductase hinge protein -2.91095
UQCRHL ubiquinol-cytochrome c reductase hinge protein-like -2.82223
C5ORF63 chromosome 5 open reading frame 63 -2.7994
PNPLA7 patatin-like phospholipase domain containing 7 -2.79526
R3HCC1 R3H domain and coiled-coil containing 1 -2.78601
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -2.69414
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.68139
TMEM14C transmembrane protein 14C -2.65955
TK1 thymidine kinase 1, soluble -2.58725
IFI16 interferon, gamma-inducible protein 16 -2.54939
SHTN1 shootin 1 -2.54911
OSBPL10 oxysterol binding protein-like 10 -2.51784
AOPEP aminopeptidase O (putative) -2.5012
TPP2 tripeptidyl peptidase II -2.48533
MYLK myosin light chain kinase -2.43906
CD247 CD247 molecule -2.43726
TUBA8 tubulin, alpha 8 -2.43726
PPP1R36 protein phosphatase 1, regulatory subunit 36 -2.43726
ZBTB17 zinc finger and BTB domain containing 17 -2.42421
KRTCAP2 keratinocyte associated protein 2 -2.42399
INTS10 integrator complex subunit 10 -2.42007
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 -2.42007
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 -2.40282
GLCCI1 glucocorticoid induced 1 -2.37909
CDK9 cyclin-dependent kinase 9 -2.37909
SPTB spectrin, beta, erythrocytic -2.37856
PPARG peroxisome proliferator-activated receptor gamma -2.37856
FAM162B family with sequence similarity 162, member B -2.37856
SCP2 sterol carrier protein 2 -2.37856
SLC39A10 solute carrier family 39 (zinc transporter), member 10 -2.36278
MATN1 matrilin 1, cartilage matrix protein -2.32956
SWAP70 SWAP switching B-cell complex 70kDa subunit -2.28818
IKZF3 IKAROS family zinc finger 3 (Aiolos) -2.28313
CRIPTO3 cripto, EGF-CFC family member 3 -2.26499
LETM2 leucine zipper-EF-hand containing transmembrane protein 2 -2.26499
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -2.2623
AKIRIN2 akirin 2 -2.20643
CLPTM1L CLPTM1-like -2.20356
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.1737
ASCC2 activating signal cointegrator 1 complex subunit 2 -2.1727
GPX8 glutathione peroxidase 8 (putative) -2.15639
SEPTIN1 septin 1 -2.13572
ADGRF3 adhesion G protein-coupled receptor F3 -2.13527
CNOT7 CCR4-NOT transcription complex, subunit 7 -2.13481
OCLN occludin -2.13361
RPL10 ribosomal protein L10 -2.13361
TIMP2 TIMP metallopeptidase inhibitor 2 -2.12544
FHIP1A FHF complex subunit HOOK interacting protein 1A -2.11734
ZNF692 zinc finger protein 692 -2.1044
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 -2.08944
BRD3 bromodomain containing 3 -2.07064
FOXO3 forkhead box O3 -2.06127
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -2.0565
RASL11B RAS-like, family 11, member B -2.05446
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -2.04335
SLC44A1 solute carrier family 44 (choline transporter), member 1 -2.03985
GID8 GID complex subunit 8 -2.02478
HEXIM2 hexamethylene bis-acetamide inducible 2 -2.01407
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 -2.01249
MBD5 methyl-CpG binding domain protein 5 -2.01249
PLA2G3 phospholipase A2, group III -2.01249
FXYD7 FXYD domain containing ion transport regulator 7 -2.01249
HBP1 HMG-box transcription factor 1 -2.01124
SLC35E4 solute carrier family 35, member E4 -2.00874