SHC4 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description SHC (Src homology 2 domain containing) family, member 4| (NCBI Entrez Gene Database, 399694)
External Link https://ncbi.nlm.nih.gov/gene/399694
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Genes

500 genes differentially expressed following the SHC4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.0190363
PUF60 poly-U binding splicing factor 60KDa 0.0167566
PROM1 prominin 1 0.0166183
ASS1 argininosuccinate synthase 1 0.0154847
MT1X metallothionein 1X 0.0150069
DLK1 delta-like 1 homolog (Drosophila) 0.0148242
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.0147737
TNNT1 troponin T type 1 (skeletal, slow) 0.0143122
G0S2 G0/G1 switch 2 0.0142119
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.0142074
PDGFRL platelet-derived growth factor receptor-like 0.0137747
COL14A1 collagen, type XIV, alpha 1 0.0135729
MDK midkine (neurite growth-promoting factor 2) 0.0129064
TSPYL5 TSPY-like 5 0.0128075
OLFM4 olfactomedin 4 0.0127772
DPYSL2 dihydropyrimidinase-like 2 0.0127008
LY6E lymphocyte antigen 6 complex, locus E 0.0126488
NEFH neurofilament, heavy polypeptide 0.0125835
QPRT quinolinate phosphoribosyltransferase 0.0123062
DCN decorin 0.0118897
ANKRD11 ankyrin repeat domain 11 0.0117969
ISLR immunoglobulin superfamily containing leucine-rich repeat 0.0117714
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.0117124
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.0116838
RTN2 reticulon 2 0.0115422
CRABP1 cellular retinoic acid binding protein 1 0.011369
MT1F metallothionein 1F 0.011252
CYBA cytochrome b-245, alpha polypeptide 0.011099
SYNGR3 synaptogyrin 3 0.0110866
COL6A2 collagen, type VI, alpha 2 0.0109901
PDE4A phosphodiesterase 4A, cAMP-specific 0.010879
TUBA1A tubulin, alpha 1a 0.010877
ECM1 extracellular matrix protein 1 0.0106471
CDC20 cell division cycle 20 0.0105006
ZNF423 zinc finger protein 423 0.010455
LGALS1 lectin, galactoside-binding, soluble, 1 0.0103649
CCL20 chemokine (C-C motif) ligand 20 0.0103159
COL16A1 collagen, type XVI, alpha 1 0.010306
ISYNA1 inositol-3-phosphate synthase 1 0.010219
PCOLCE procollagen C-endopeptidase enhancer 0.0101709
STC2 stanniocalcin 2 0.0101063
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.0100614
ITM2C integral membrane protein 2C 0.0100564
KRT19 keratin 19, type I 0.0100437
CLEC11A C-type lectin domain family 11, member A 0.00990947
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00987531
CLEC3B C-type lectin domain family 3, member B 0.00976173
SCPEP1 serine carboxypeptidase 1 0.00966176
MMP7 matrix metallopeptidase 7 0.00964076
TPPP3 tubulin polymerization-promoting protein family member 3 0.00962569
FBLN1 fibulin 1 0.00962374
MT1G metallothionein 1G 0.00950497
PDLIM5 PDZ and LIM domain 5 0.00946823
SLC39A4 solute carrier family 39 (zinc transporter), member 4 0.00945145
MXRA7 matrix-remodelling associated 7 0.00936531
SRPX sushi-repeat containing protein, X-linked 0.00935669
LCN2 lipocalin 2 0.00928369
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.00928318
SPON2 spondin 2, extracellular matrix protein 0.00926892
OGN osteoglycin 0.00921149
THY1 Thy-1 cell surface antigen 0.00919344
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.00916748
LTBP4 latent transforming growth factor beta binding protein 4 0.00915705
ACTA1 actin, alpha 1, skeletal muscle 0.00910826
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.00905464
CHKB choline kinase beta 0.00898339
TNIP1 TNFAIP3 interacting protein 1 0.00895511
MLF1 myeloid leukemia factor 1 0.00892969
IRF7 interferon regulatory factor 7 0.00887256
NEFM neurofilament, medium polypeptide 0.00885978
UPP1 uridine phosphorylase 1 0.00883109
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.00875927
SPINT1 serine peptidase inhibitor, Kunitz type 1 0.00873123
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00871828
GPX7 glutathione peroxidase 7 0.0087051
BIN1 bridging integrator 1 0.00870027
PDLIM2 PDZ and LIM domain 2 (mystique) 0.0086705
GPM6B glycoprotein M6B 0.0086546
MT1H metallothionein 1H 0.00861773
PLXNB2 plexin B2 0.00860262
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.00860166
RORA RAR-related orphan receptor A 0.00859128
ASPN asporin 0.00855461
SIDT2 SID1 transmembrane family, member 2 0.00846502
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.00845232
NOTCH1 notch 1 0.0084469
WDR45 WD repeat domain 45 0.00843828
DACH1 dachshund family transcription factor 1 0.00842058
PENK proenkephalin 0.00841845
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.00841324
NPY1R neuropeptide Y receptor Y1 0.0083844
EXOSC4 exosome component 4 0.00837396
HEPH hephaestin 0.00834606
FBLN2 fibulin 2 0.00834269
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.00833531
TMX4 thioredoxin-related transmembrane protein 4 0.0083182
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 0.00825001
PTN pleiotrophin 0.00824483
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 0.00824382
ANK2 ankyrin 2, neuronal 0.00819782
ANXA4 annexin A4 0.00818632
LAMP5 lysosomal-associated membrane protein family, member 5 0.00813774
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 0.0081025
EIF4E2 eukaryotic translation initiation factor 4E family member 2 0.0080961
AHCY adenosylhomocysteinase 0.00808156
C14ORF132 chromosome 14 open reading frame 132 0.00808093
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00806121
GOLGA8H golgin A8 family, member H 0.00805681
RABAC1 Rab acceptor 1 (prenylated) 0.00804833
ADRM1 adhesion regulating molecule 1 0.00803171
PNMA2 paraneoplastic Ma antigen 2 0.00801819
GSDME gasdermin E 0.00801254
ZGPAT zinc finger, CCCH-type with G patch domain 0.00797084
DBN1 drebrin 1 0.00796297
PLBD1 phospholipase B domain containing 1 0.00794744
CXCL14 chemokine (C-X-C motif) ligand 14 0.00792796
SCAND1 SCAN domain containing 1 0.00785975
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.00785105
IGF1 insulin-like growth factor 1 (somatomedin C) 0.007805
NUDC nudC nuclear distribution protein 0.00778048
PNMA8A PNMA family member 8A 0.00777304
FLNC filamin C, gamma 0.00776294
EMP3 epithelial membrane protein 3 0.00771036
TUBB2B tubulin, beta 2B class IIb 0.00770099
TBCB tubulin folding cofactor B 0.00769827
VCAN versican 0.00769134
HSPA1A heat shock 70kDa protein 1A 0.00764255
IL17RB interleukin 17 receptor B 0.00763859
DES desmin 0.0076366
EGFL6 EGF-like-domain, multiple 6 0.00761051
MAP9 microtubule-associated protein 9 0.00760908
SMAD3 SMAD family member 3 0.00760442
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00759585
LTBP2 latent transforming growth factor beta binding protein 2 0.00757787
KRT8 keratin 8, type II 0.00757699
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 0.00757457
WTAP Wilms tumor 1 associated protein 0.00755769
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00753796
HSPH1 heat shock 105kDa/110kDa protein 1 0.00750703
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.00750369
BOP1 block of proliferation 1 0.00746783
DGAT1 diacylglycerol O-acyltransferase 1 0.00745528
SORBS3 sorbin and SH3 domain containing 3 0.00745369
DCLK1 doublecortin-like kinase 1 0.00744433
FRZB frizzled-related protein 0.00743015
FTH1 ferritin, heavy polypeptide 1 0.00741721
NPDC1 neural proliferation, differentiation and control, 1 0.00739683
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00737124
TAC1 tachykinin, precursor 1 0.00736496
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00735765
GNAS GNAS complex locus 0.00735685
RAP1GAP2 RAP1 GTPase activating protein 2 0.00735306
OBSL1 obscurin-like 1 0.00733777
TAGLN transgelin 0.00733058
LAMC2 laminin, gamma 2 0.0073138
KIAA0930 KIAA0930 0.00730769
PGLS 6-phosphogluconolactonase 0.00730015
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00727455
LEFTY1 left-right determination factor 1 0.00726398
SCG5 secretogranin V 0.00724815
PPIF peptidylprolyl isomerase F 0.00724734
NRIP3 nuclear receptor interacting protein 3 0.00724479
POU2AF1 POU class 2 associating factor 1 0.00722707
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00721362
CRIP1 cysteine-rich protein 1 (intestinal) 0.00719384
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00713473
KLF11 Kruppel-like factor 11 0.00712351
CKM creatine kinase, muscle 0.00710704
SMAD7 SMAD family member 7 0.007106
S100P S100 calcium binding protein P 0.00709562
SFRP4 secreted frizzled-related protein 4 0.00707284
CFB complement factor B 0.00706167
TNNC2 troponin C type 2 (fast) 0.00704985
TXLNA taxilin alpha 0.00703271
TCF25 transcription factor 25 (basic helix-loop-helix) 0.00702759
AEBP1 AE binding protein 1 0.00701261
MT1HL1 metallothionein 1H-like 1 0.00701116
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.00700858
NOSIP nitric oxide synthase interacting protein 0.00700272
EPS8L2 EPS8-like 2 0.00699522
COL9A3 collagen, type IX, alpha 3 0.00698593
MNT MAX network transcriptional repressor 0.00698458
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 0.00697398
OSR2 odd-skipped related transciption factor 2 0.00697132
FBXO2 F-box protein 2 0.00693847
PRR13 proline rich 13 0.00693108
CD79A CD79a molecule, immunoglobulin-associated alpha 0.00693055
SMTN smoothelin 0.00692929
PBLD phenazine biosynthesis-like protein domain containing 0.00690868
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.00687369
NT5E 5'-nucleotidase, ecto (CD73) 0.00684653
MAPKBP1 mitogen-activated protein kinase binding protein 1 0.00682801
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 0.00677782
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.00676726
TUBA4A tubulin, alpha 4a 0.00676247
STK26 serine/threonine protein kinase 26 0.0067495
OPLAH 5-oxoprolinase (ATP-hydrolysing) 0.00673622
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.00669294
EDNRA endothelin receptor type A 0.00669098
KLHL41 kelch-like family member 41 0.00669061
FKBP9 FK506 binding protein 9, 63 kDa 0.00667483
AMPD2 adenosine monophosphate deaminase 2 0.00666254
CCDC69 coiled-coil domain containing 69 0.00663736
DDRGK1 DDRGK domain containing 1 0.00663338
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.00663021
RBM34 RNA binding motif protein 34 0.00662602
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.00661025
NXN nucleoredoxin 0.00660026
INAVA innate immunity activator 0.00659927
ZFP36L2 ZFP36 ring finger protein-like 2 0.00657452
PDZRN3 PDZ domain containing ring finger 3 0.00657356
CTSK cathepsin K 0.0065714
PRKCZ protein kinase C, zeta 0.00655081
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 0.00655038
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae) 0.00654671
MAGED1 melanoma antigen family D1 0.00654277
ELN elastin 0.00652542
CHRDL1 chordin-like 1 0.00652142
CCL21 chemokine (C-C motif) ligand 21 0.00651351
HIP1R huntingtin interacting protein 1 related 0.00650612
UGDH UDP-glucose 6-dehydrogenase 0.00650509
CCND2 cyclin D2 0.00649895
MT1E metallothionein 1E 0.00649801
FILIP1L filamin A interacting protein 1-like 0.00649574
ZBED1 zinc finger, BED-type containing 1 0.0064951
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00648903
HSF1 heat shock transcription factor 1 0.00648782
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 0.0064789
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.0064767
PEG3 paternally expressed 3 0.00647498
ABAT 4-aminobutyrate aminotransferase 0.00647497
EIF6 eukaryotic translation initiation factor 6 0.00645081
ECM2 extracellular matrix protein 2, female organ and adipocyte specific 0.0064477
GUSB glucuronidase, beta 0.00644712
BANP BTG3 associated nuclear protein 0.00643599
LAMB3 laminin, beta 3 0.00643361
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00643221
RNF19B ring finger protein 19B 0.00642847
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00642794
XYLT1 xylosyltransferase I 0.00642564
CLDN3 claudin 3 0.00642244
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.00641957
ADD3 adducin 3 (gamma) 0.00641205
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.00640956
SIKE1 suppressor of IKBKE 1 0.00640381
GREM1 gremlin 1, DAN family BMP antagonist 0.0064025
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.00639657
EMILIN1 elastin microfibril interfacer 1 0.00637983
TCL1A T-cell leukemia/lymphoma 1A 0.00636397
FAM110B family with sequence similarity 110, member B 0.00636328

decreased expression

Symbol Name Standardized Value
CXCL10 chemokine (C-X-C motif) ligand 10 -0.0187652
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0175051
TM9SF3 transmembrane 9 superfamily member 3 -0.0174739
EXOC5 exocyst complex component 5 -0.0146527
SRSF1 serine/arginine-rich splicing factor 1 -0.0140508
CXADR coxsackie virus and adenovirus receptor -0.0136584
SCARB2 scavenger receptor class B, member 2 -0.0136529
SNX11 sorting nexin 11 -0.013256
ZDHHC6 zinc finger, DHHC-type containing 6 -0.0129522
ABLIM1 actin binding LIM protein 1 -0.012876
CA2 carbonic anhydrase II -0.0124547
ADAM10 ADAM metallopeptidase domain 10 -0.0124464
CD2 CD2 molecule -0.0116938
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.0116227
MAP7 microtubule-associated protein 7 -0.0115531
GBP1 guanylate binding protein 1, interferon-inducible -0.0114275
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.0111182
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -0.0109112
MED1 mediator complex subunit 1 -0.0109077
CD164 CD164 molecule, sialomucin -0.0108828
CXCL11 chemokine (C-X-C motif) ligand 11 -0.0108262
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0106671
CCNA2 cyclin A2 -0.0104181
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0103708
CLEC2B C-type lectin domain family 2, member B -0.0103611
RHOBTB3 Rho-related BTB domain containing 3 -0.0102857
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0101493
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0101484
GTF2I general transcription factor IIi -0.0101045
AIM2 absent in melanoma 2 -0.0100624
TMOD3 tropomodulin 3 (ubiquitous) -0.0100335
LMAN1 lectin, mannose-binding, 1 -0.00999263
CSTA cystatin A (stefin A) -0.00995401
CCR7 chemokine (C-C motif) receptor 7 -0.00990219
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00974269
ITGA6 integrin, alpha 6 -0.0097155
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -0.00969501
MYOF myoferlin -0.00961281
S100A2 S100 calcium binding protein A2 -0.00960585
YIPF5 Yip1 domain family, member 5 -0.00957865
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -0.00956011
NELL1 NEL-like 1 (chicken) -0.00954515
NNT nicotinamide nucleotide transhydrogenase -0.00945966
RHOA ras homolog family member A -0.00939308
CEP55 centrosomal protein 55kDa -0.00929705
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00928728
CBX1 chromobox homolog 1 -0.0092753
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -0.00919389
MMP12 matrix metallopeptidase 12 -0.00917963
RDX radixin -0.0090792
EML4 echinoderm microtubule associated protein like 4 -0.00905626
CD59 CD59 molecule, complement regulatory protein -0.00902925
GLUL glutamate-ammonia ligase -0.00894932
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa -0.00890498
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00888428
IFI44L interferon-induced protein 44-like -0.00884018
SLC39A9 solute carrier family 39, member 9 -0.00881839
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 -0.0088039
TFEC transcription factor EC -0.00879182
PPARG peroxisome proliferator-activated receptor gamma -0.00873874
ELL2 elongation factor, RNA polymerase II, 2 -0.00872831
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00872245
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -0.00870203
SCAMP1 secretory carrier membrane protein 1 -0.00868169
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -0.00867687
CANX calnexin -0.00866469
PCLAF PCNA clamp associated factor -0.00866
NDFIP1 Nedd4 family interacting protein 1 -0.00863774
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -0.0086315
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00861603
TMEM14A transmembrane protein 14A -0.00861489
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00857019
IDO1 indoleamine 2,3-dioxygenase 1 -0.00856326
ZWILCH zwilch kinetochore protein -0.00849529
IFRD2 interferon-related developmental regulator 2 -0.00845296
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00841951
TMEM14B transmembrane protein 14B -0.00836292
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.00835393
HOXB7 homeobox B7 -0.00834895
COMMD10 COMM domain containing 10 -0.00832375
GBP2 guanylate binding protein 2, interferon-inducible -0.00820206
GTF2A2 general transcription factor IIA, 2, 12kDa -0.00818068
ACTB actin, beta -0.00817734
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -0.00814461
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00806788
ZBTB38 zinc finger and BTB domain containing 38 -0.00798161
PBK PDZ binding kinase -0.00795607
CAV2 caveolin 2 -0.00793174
ACP6 acid phosphatase 6, lysophosphatidic -0.00792402
PDE4B phosphodiesterase 4B, cAMP-specific -0.00790957
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -0.00790774
CLIP1 CAP-GLY domain containing linker protein 1 -0.00789184
CAPRIN1 cell cycle associated protein 1 -0.0078837
ADAM28 ADAM metallopeptidase domain 28 -0.0078827
LAMP3 lysosomal-associated membrane protein 3 -0.00781869
SPTSSA serine palmitoyltransferase, small subunit A -0.00781235
MBTPS2 membrane-bound transcription factor peptidase, site 2 -0.00780975
CYB5A cytochrome b5 type A (microsomal) -0.00777845
NTS neurotensin -0.00776356
TMEM230 transmembrane protein 230 -0.0077548
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -0.00774282
GIMAP5 GTPase, IMAP family member 5 -0.00773137
NPR3 natriuretic peptide receptor 3 -0.00772841
IPO7 importin 7 -0.00768039
CHMP5 charged multivesicular body protein 5 -0.00765127
RAD23B RAD23 homolog B (S. cerevisiae) -0.00765039
NMD3 NMD3 ribosome export adaptor -0.00763375
GCA grancalcin, EF-hand calcium binding protein -0.0076265
ANXA1 annexin A1 -0.00762616
CAPN7 calpain 7 -0.00762459
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.00760322
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.00756123
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.00753969
CCL14 chemokine (C-C motif) ligand 14 -0.00753755
TSPAN6 tetraspanin 6 -0.00753694
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.00752776
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.00748018
CLDND1 claudin domain containing 1 -0.00747978
MAT2B methionine adenosyltransferase II, beta -0.00747931
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) -0.00745679
ATG5 autophagy related 5 -0.00744895
TFDP1 transcription factor Dp-1 -0.00740191
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -0.00739352
SGPP1 sphingosine-1-phosphate phosphatase 1 -0.00737965
CD46 CD46 molecule, complement regulatory protein -0.00737069
ATAD2 ATPase family, AAA domain containing 2 -0.00736871
MOCS2 molybdenum cofactor synthesis 2 -0.0073575
TLR4 toll-like receptor 4 -0.00733563
NCK1 NCK adaptor protein 1 -0.00732254
STAT1 signal transducer and activator of transcription 1, 91kDa -0.00732052
KCTD20 potassium channel tetramerization domain containing 20 -0.00730985
MRPL42 mitochondrial ribosomal protein L42 -0.00728977
DLG1 discs, large homolog 1 (Drosophila) -0.00727325
CA9 carbonic anhydrase IX -0.00727232
PEX3 peroxisomal biogenesis factor 3 -0.00726323
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 -0.00725888
HCP5 HLA complex P5 (non-protein coding) -0.00725276
GPHN gephyrin -0.00725236
KPNB1 karyopherin (importin) beta 1 -0.00725041
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -0.00722025
EPAS1 endothelial PAS domain protein 1 -0.00720467
IL6ST interleukin 6 signal transducer -0.00719156
IL18 interleukin 18 -0.00717883
CLEC5A C-type lectin domain family 5, member A -0.00717843
SMAD5 SMAD family member 5 -0.00717813
TXN thioredoxin -0.00717494
ABHD17B abhydrolase domain containing 17B -0.0071481
COG5 component of oligomeric golgi complex 5 -0.00714314
SPRR3 small proline-rich protein 3 -0.00714149
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.00709175
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -0.00708332
AGPS alkylglycerone phosphate synthase -0.00707829
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00707814
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 -0.00707174
IARS1 isoleucyl-tRNA synthetase 1 -0.00706706
RAB32 RAB32, member RAS oncogene family -0.00706337
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) -0.00705415
RALB v-ral simian leukemia viral oncogene homolog B -0.00705169
KIF20A kinesin family member 20A -0.0070473
MRPL36 mitochondrial ribosomal protein L36 -0.00703791
CD1E CD1e molecule -0.0070341
UBA6 ubiquitin-like modifier activating enzyme 6 -0.00699877
CPD carboxypeptidase D -0.00699663
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -0.00699056
MCTP1 multiple C2 domains, transmembrane 1 -0.00698613
CD48 CD48 molecule -0.00698048
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -0.00697696
PRB4 proline-rich protein BstNI subfamily 4 -0.00697678
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) -0.0069672
HIPK3 homeodomain interacting protein kinase 3 -0.00696477
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.00692807
MRPS16 mitochondrial ribosomal protein S16 -0.00692749
TARBP1 TAR (HIV-1) RNA binding protein 1 -0.00691542
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00691302
MPZL2 myelin protein zero-like 2 -0.00690865
SET SET nuclear proto-oncogene -0.00690224
ANO10 anoctamin 10 -0.00689116
PRIM2 primase, DNA, polypeptide 2 (58kDa) -0.00687637
ANKFY1 ankyrin repeat and FYVE domain containing 1 -0.00687382
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00686111
SHTN1 shootin 1 -0.00683897
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -0.00683662
POT1 protection of telomeres 1 -0.00681871
SLAMF8 SLAM family member 8 -0.00681771
IDE insulin-degrading enzyme -0.00681522
PHB prohibitin -0.00681333
MAGT1 magnesium transporter 1 -0.00674443
HOXB6 homeobox B6 -0.00672991
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00672764
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00671965
AUTS2 autism susceptibility candidate 2 -0.00671863
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -0.0067084
STATH statherin -0.00670812
MTARC2 mitochondrial amidoxime reducing component 2 -0.00669963
KIF11 kinesin family member 11 -0.00669527
ASF1A anti-silencing function 1A histone chaperone -0.00669222
MCL1 myeloid cell leukemia 1 -0.00668492
TUBGCP4 tubulin, gamma complex associated protein 4 -0.00667093
C1QA complement component 1, q subcomponent, A chain -0.00666101
CCDC6 coiled-coil domain containing 6 -0.00665818
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -0.00665613
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00665148
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -0.00664119
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00663515
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -0.00663152
ATP5F1C ATP synthase F1 subunit gamma -0.00660975
CD163 CD163 molecule -0.00658561
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00658274
PLEK2 pleckstrin 2 -0.00655368
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) -0.00653738
KRCC1 lysine-rich coiled-coil 1 -0.00653331
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00651578
RNFT1 ring finger protein, transmembrane 1 -0.00651346
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00651173
PEA15 phosphoprotein enriched in astrocytes 15 -0.00651128
MGST3 microsomal glutathione S-transferase 3 -0.00650712
BTG3 BTG family, member 3 -0.00650163
RSL24D1 ribosomal L24 domain containing 1 -0.0064971
RAB14 RAB14, member RAS oncogene family -0.00649494
TMEM168 transmembrane protein 168 -0.00649387
TMEM260 transmembrane protein 260 -0.00648191
LYZ lysozyme -0.00647479
ZMYND11 zinc finger, MYND-type containing 11 -0.00646302
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.00646096
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.00645657
IL2RG interleukin 2 receptor, gamma -0.00645559
ADAMDEC1 ADAM-like, decysin 1 -0.00645159
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.0064441
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) -0.0064399
FNTB farnesyltransferase, CAAX box, beta -0.00643531
ENSA endosulfine alpha -0.00642248
FYB1 FYN binding protein 1 -0.00640991
ADGRE1 adhesion G protein-coupled receptor E1 -0.00640856
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.00640508
CHM choroideremia (Rab escort protein 1) -0.00639486
KIF1B kinesin family member 1B -0.00636636
UTRN utrophin -0.00636607
UPK1B uroplakin 1B -0.00636238
IREB2 iron-responsive element binding protein 2 -0.00636076
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -0.00635604
COL4A2 collagen, type IV, alpha 2 -0.00635034
RGCC regulator of cell cycle -0.00634481
TSC22D1 TSC22 domain family, member 1 -0.00632803
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -0.00632171
FBXW2 F-box and WD repeat domain containing 2 -0.00631172
COX7B cytochrome c oxidase subunit VIIb -0.00630914
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -0.00629716
TMPRSS4 transmembrane protease, serine 4 -0.00626996
MNDA myeloid cell nuclear differentiation antigen -0.00626595
RPL14 ribosomal protein L14 -0.0062647