SHISA3 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description shisa family member 3 (NCBI Entrez Gene Database, 152573)
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Genes

367 genes differentially expressed following the SHISA3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TMPRSS11A transmembrane protease, serine 11A 2.53993
NXPH3 neurexophilin 3 2.53993
MGAM2 maltase-glucoamylase 2 (putative) 2.53993
TM4SF1 transmembrane 4 L six family member 1 2.53993
ZDHHC8 zinc finger, DHHC-type containing 8 2.53993
UNC13C unc-13 homolog C (C. elegans) 2.53993
TM4SF20 transmembrane 4 L six family member 20 2.53993
NME4 NME/NM23 nucleoside diphosphate kinase 4 2.53993
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.53993
OR2J3 olfactory receptor, family 2, subfamily J, member 3 2.53993
PTH2 parathyroid hormone 2 2.53993
PAX7 paired box 7 2.53993
CABP4 calcium binding protein 4 2.53993
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 2.53993
CD1D CD1d molecule 2.53993
RNF17 ring finger protein 17 2.53993
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.53993
LRRD1 leucine-rich repeats and death domain containing 1 2.53993
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.53993
WDR87 WD repeat domain 87 2.53993
COLEC10 collectin sub-family member 10 (C-type lectin) 2.53993
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 2.53993
SCG2 secretogranin II 2.53993
KNG1 kininogen 1 2.53993
SLC46A2 solute carrier family 46, member 2 2.53993
LRRTM2 leucine rich repeat transmembrane neuronal 2 2.53993
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 2.53993
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 2.53993
EPHX4 epoxide hydrolase 4 2.53993
PCDHB6 protocadherin beta 6 2.53993
NPIPA7 nuclear pore complex interacting protein family, member A7 2.53993
WWC1 WW and C2 domain containing 1 2.53993
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 2.53993
BFSP2 beaded filament structural protein 2, phakinin 2.53993
VSX1 visual system homeobox 1 2.53993
CORO6 coronin 6 2.53993
LGALS9 lectin, galactoside-binding, soluble, 9 2.53993
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1 2.53993
SPN sialophorin 2.53993
HMX3 H6 family homeobox 3 2.53993
LGI1 leucine-rich, glioma inactivated 1 2.53993
SOWAHB sosondowah ankyrin repeat domain family member B 2.53993
OCSTAMP osteoclast stimulatory transmembrane protein 2.53993
FETUB fetuin B 2.53993
C6ORF58 chromosome 6 open reading frame 58 2.53993
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 2.53993
TCHHL1 trichohyalin-like 1 2.53993
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.53993
C19ORF67 chromosome 19 open reading frame 67 2.53993
MYOM2 myomesin 2 2.53993
SLC9C2 solute carrier family 9, member C2 (putative) 2.53993
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 2.53993
C1ORF141 chromosome 1 open reading frame 141 2.53993
OR2AJ1 olfactory receptor, family 2, subfamily AJ, member 1 2.53993
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 2.53993
PNMA6F PNMA family member 6F 2.53993
PROP1 PROP paired-like homeobox 1 2.53993
MGAM maltase-glucoamylase 2.53993
RHCG Rh family, C glycoprotein 2.53993
TBC1D3L TBC1 domain family, member 3L 2.53993
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 2.53993
TRIM31 tripartite motif containing 31 2.53993
PROZ protein Z, vitamin K-dependent plasma glycoprotein 2.53993
MYL10 myosin, light chain 10, regulatory 2.53993
TSPAN1 tetraspanin 1 2.53993
OR51M1 olfactory receptor, family 51, subfamily M, member 1 2.53993
IMPG1 interphotoreceptor matrix proteoglycan 1 2.53993
YPEL4 yippee-like 4 (Drosophila) 2.53993
SQOR sulfide quinone oxidoreductase 2.53993
MYOCOS myocilin opposite strand 2.53993
NOTCH2NLB notch 2 N-terminal like B 2.53993
LOC122526780 uncharacterized LOC122526780 2.53993
SMIM31 small integral membrane protein 31 2.53993
MINDY4B MINDY family member 4B 2.53993
GLYATL1B glycine-N-acyltransferase like 1B 2.53993
H2BW1 H2B.W histone 1 2.53993
CATSPERZ catsper channel auxiliary subunit zeta 2.53993
BNIP5 BCL2 interacting protein 5 2.53993
MSANTD5 Myb/SANT DNA binding domain containing 5 2.53993
CBLIF cobalamin binding intrinsic factor 2.53993
SMIM38 small integral membrane protein 38 2.53993
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 2.53993
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 2.53993
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 2.53993
RPL19 ribosomal protein L19 2.53993
STYK1 serine/threonine/tyrosine kinase 1 2.53993
C10ORF67 chromosome 10 open reading frame 67 2.53993
SCN10A sodium channel, voltage gated, type X alpha subunit 2.53993
ZBTB16 zinc finger and BTB domain containing 16 2.53993
IRF8 interferon regulatory factor 8 2.53993
SCRG1 stimulator of chondrogenesis 1 2.53993
GMEB1 glucocorticoid modulatory element binding protein 1 2.53993
FPR1 formyl peptide receptor 1 2.53993
TBX20 T-box 20 2.53993
WEE2 WEE1 homolog 2 (S. pombe) 2.53993
TPTE transmembrane phosphatase with tensin homology 2.53993
HSPB6 heat shock protein, alpha-crystallin-related, B6 2.53993
RASAL3 RAS protein activator like 3 2.53993
ARL14EPL ADP-ribosylation factor-like 14 effector protein-like 2.53993
GATA1 GATA binding protein 1 (globin transcription factor 1) 2.53993
KL klotho 2.53993
OSTN osteocrin 2.53993
LTA lymphotoxin alpha 2.53993
WBP11 WW domain binding protein 11 2.53993
LRRC71 leucine rich repeat containing 71 2.53993
DNAL4 dynein, axonemal, light chain 4 2.53993
FAM131C family with sequence similarity 131, member C 2.53993
CCR9 chemokine (C-C motif) receptor 9 2.53993
PIWIL1 piwi-like RNA-mediated gene silencing 1 2.53993
SIX1 SIX homeobox 1 2.53993
THEMIS thymocyte selection associated 2.53993
MAGEB17 melanoma antigen family B17 2.53993
HPX hemopexin 2.53993
TMEM204 transmembrane protein 204 2.53993
PKDREJ polycystin (PKD) family receptor for egg jelly 2.53993
PAGE4 P antigen family, member 4 (prostate associated) 2.53993
POU2AF1 POU class 2 associating factor 1 2.53993
TLR10 toll-like receptor 10 2.53993
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 2.53993
DRD3 dopamine receptor D3 2.53993
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 2.53993
FAM135B family with sequence similarity 135, member B 2.53993
TBC1D10C TBC1 domain family, member 10C 2.53993
XK X-linked Kx blood group 2.53993
FBXO39 F-box protein 39 2.53993
ZNF366 zinc finger protein 366 2.53993
PALMD palmdelphin 2.53993
NOG noggin 2.53993
CST7 cystatin F (leukocystatin) 2.53993
TMEM161B transmembrane protein 161B 2.53993
GPR12 G protein-coupled receptor 12 2.53993
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 2.53993
MAMDC4 MAM domain containing 4 2.53993
AQP9 aquaporin 9 2.53993
ZNF843 zinc finger protein 843 2.53993
KLK4 kallikrein-related peptidase 4 2.53993
ASTL astacin-like metallo-endopeptidase (M12 family) 2.53993
REG1A regenerating islet-derived 1 alpha 2.53993
PLAC8L1 PLAC8-like 1 2.53993
LRRN4 leucine rich repeat neuronal 4 2.53993
TTC24 tetratricopeptide repeat domain 24 2.53993
C22ORF31 chromosome 22 open reading frame 31 2.53993
ZNF831 zinc finger protein 831 2.53993
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 2.53993
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 2.53993
OR52N1 olfactory receptor, family 52, subfamily N, member 1 2.53993
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 2.53993
C11ORF42 chromosome 11 open reading frame 42 2.53993
GPR149 G protein-coupled receptor 149 2.53993
ZC3H11D zinc finger CCCH-type containing 11D 2.53993
LY96 lymphocyte antigen 96 2.53993
ITGB7 integrin, beta 7 2.53993
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 2.53993
OTOP2 otopetrin 2 2.53993
GPR61 G protein-coupled receptor 61 2.53993
UBXN10 UBX domain protein 10 2.53993
CD28 CD28 molecule 2.53993
LYPD5 LY6/PLAUR domain containing 5 2.53993
INSL3 insulin-like 3 (Leydig cell) 2.53993
PAGR1 PAXIP1 associated glutamate-rich protein 1 2.53993
HCAR1 hydroxycarboxylic acid receptor 1 2.53993
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 2.53993
FADS6 fatty acid desaturase 6 2.53993
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) 2.53993
MMP3 matrix metallopeptidase 3 2.53993
IL33 interleukin 33 2.53993
DHRS9 dehydrogenase/reductase (SDR family) member 9 2.53993
HHIPL2 HHIP-like 2 2.53993
KIF26A kinesin family member 26A 2.53993
SOST sclerostin 2.53993
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 2.53993
CD22 CD22 molecule 2.53993
RNF222 ring finger protein 222 2.53993
CD101 CD101 molecule 2.53993
OR56B4 olfactory receptor, family 56, subfamily B, member 4 2.53993
APRT adenine phosphoribosyltransferase 2.53993
CHAD chondroadherin 2.53993
AMER3 APC membrane recruitment protein 3 2.53993
SCN3A sodium channel, voltage gated, type III alpha subunit 2.53993
PRR29 proline rich 29 2.53993
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.53993
RXRG retinoid X receptor, gamma 2.53993
STAP1 signal transducing adaptor family member 1 2.53993
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) 2.53993
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 2.53993
IFNK interferon, kappa 2.53993
PCDHGA11 protocadherin gamma subfamily A, 11 2.53993
ELMOD1 ELMO/CED-12 domain containing 1 2.53993
EIF3E eukaryotic translation initiation factor 3, subunit E 2.53993
NUTM2A NUT family member 2A 2.53993
ANKRD33 ankyrin repeat domain 33 2.53993
FAM81B family with sequence similarity 81, member B 2.53993
ANGPTL6 angiopoietin-like 6 2.53993
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 2.53993
C2ORF81 chromosome 2 open reading frame 81 2.49053
PRELID3B PRELI domain containing 3B 2.43799
ZNF441 zinc finger protein 441 2.432
PRDM7 PR domain containing 7 2.432
USP11 ubiquitin specific peptidase 11 2.432
PRB2 proline-rich protein BstNI subfamily 2 2.432
SPINK1 serine peptidase inhibitor, Kazal type 1 2.432
TUBA4B tubulin, alpha 4b 2.432
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 2.42757
SYNPO2L synaptopodin 2-like 2.39994
VEGFB vascular endothelial growth factor B 2.39994
SPEF2 sperm flagellar 2 2.39994
CHCT1 CHD1 helical C-terminal domain containing 1 2.38514
TSLIG1 tRNA splicing ligase complex subunit 1 2.38454
CCDC107 coiled-coil domain containing 107 2.37064
CRYGN crystallin, gamma N 2.36805
CD72 CD72 molecule 2.35506
ACO2 aconitase 2, mitochondrial 2.33458
RBM12B RNA binding motif protein 12B 2.33458
TRIOBP TRIO and F-actin binding protein 2.32445
IFFO2 intermediate filament family orphan 2 2.32324
ADAT3 adenosine deaminase, tRNA-specific 3 2.32324
ZNF892 zinc finger protein 892 2.32324
FNDC7 fibronectin type III domain containing 7 2.32324
ITGA1 integrin, alpha 1 2.31888
TTC7A tetratricopeptide repeat domain 7A 2.28229
SHLD1 shieldin complex subunit 1 2.28121
MGST2 microsomal glutathione S-transferase 2 2.24204
IP6K1 inositol hexakisphosphate kinase 1 2.23356
RGS7BP regulator of G-protein signaling 7 binding protein 2.22556
WDR7 WD repeat domain 7 2.22476
RHOT2 ras homolog family member T2 2.21698
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 2.196
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 2.19447
ZNF497 zinc finger protein 497 2.18866
FUBP3 far upstream element (FUSE) binding protein 3 2.17994
RFX4 regulatory factor X, 4 (influences HLA class II expression) 2.17181
CIB2 calcium and integrin binding family member 2 2.16259
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 2.14717
RPA3 replication protein A3, 14kDa 2.1428
TOR3A torsin family 3, member A 2.13537
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 2.11616
LARP6 La ribonucleoprotein domain family, member 6 2.11561
CTCFL CCCTC-binding factor (zinc finger protein)-like 2.11561
NMT1 N-myristoyltransferase 1 2.09092
SPDYE12 speedy/RINGO cell cycle regulator family member E12 2.08691
SLC39A10 solute carrier family 39 (zinc transporter), member 10 2.07062
PRR14 proline rich 14 2.06203
SLX9 SLX9 ribosome biogenesis factor 2.05429
FSTL5 follistatin-like 5 2.04266
PCTP phosphatidylcholine transfer protein 2.04239
HINT1 histidine triad nucleotide binding protein 1 2.02948
SCD stearoyl-CoA desaturase (delta-9-desaturase) 2.02948
ATG101 autophagy related 101 2.01731
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.01731
ABRAXAS2 abraxas 2, BRISC complex subunit 2.01311

decreased expression

Symbol Name Standardized Value
SPMIP3 sperm microtubule inner protein 3 -2.53993
PERP PERP, TP53 apoptosis effector -2.53993
PTK6 protein tyrosine kinase 6 -2.53993
IL6R interleukin 6 receptor -2.53993
MMP28 matrix metallopeptidase 28 -2.53993
MPL MPL proto-oncogene, thrombopoietin receptor -2.53993
HARBI1 harbinger transposase derived 1 -2.53993
C12ORF42 chromosome 12 open reading frame 42 -2.53993
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -2.53993
ZNF487 zinc finger protein 487 -2.53993
HMGA2 high mobility group AT-hook 2 -2.53993
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 -2.53993
ZNF396 zinc finger protein 396 -2.53993
TMEM81 transmembrane protein 81 -2.53993
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 -2.53993
CLCNKB chloride channel, voltage-sensitive Kb -2.53993
LONP1 lon peptidase 1, mitochondrial -2.53993
NALCN sodium leak channel, non selective -2.53993
MFAP4 microfibrillar-associated protein 4 -2.53993
DNAI7 dynein axonemal intermediate chain 7 -2.53993
TPP2 tripeptidyl peptidase II -2.53993
MYB v-myb avian myeloblastosis viral oncogene homolog -2.53993
STARD6 StAR-related lipid transfer (START) domain containing 6 -2.53993
ADI1 acireductone dioxygenase 1 -2.53993
C1QTNF1 C1q and tumor necrosis factor related protein 1 -2.53993
ULBP3 UL16 binding protein 3 -2.53993
CTBS chitobiase, di-N-acetyl- -2.53993
ELAVL3 ELAV like neuron-specific RNA binding protein 3 -2.53993
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z -2.53993
CFHR3 complement factor H-related 3 -2.53993
SLC26A9 solute carrier family 26 (anion exchanger), member 9 -2.53993
SLC46A3 solute carrier family 46, member 3 -2.53993
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) -2.53993
NXPH4 neurexophilin 4 -2.53993
NOXO1 NADPH oxidase organizer 1 -2.53993
SFN stratifin -2.53993
ECE2 endothelin converting enzyme 2 -2.53993
SCML2 sex comb on midleg-like 2 (Drosophila) -2.53993
KLF4 Kruppel-like factor 4 (gut) -2.53993
UGT8 UDP glycosyltransferase 8 -2.53993
BRDT bromodomain, testis-specific -2.53993
COL28A1 collagen, type XXVIII, alpha 1 -2.53993
CTBP2 C-terminal binding protein 2 -2.53993
WNT3 wingless-type MMTV integration site family, member 3 -2.53993
CFAP126 cilia and flagella associated protein 126 -2.53993
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B -2.53993
FGR FGR proto-oncogene, Src family tyrosine kinase -2.53993
RLF rearranged L-myc fusion -2.53993
VSTM1 V-set and transmembrane domain containing 1 -2.53993
FAM111A family with sequence similarity 111, member A -2.53993
RELT RELT tumor necrosis factor receptor -2.53993
MSMP microseminoprotein, prostate associated -2.53993
GP1BA glycoprotein Ib (platelet), alpha polypeptide -2.53993
SCX scleraxis basic helix-loop-helix transcription factor -2.53993
MTFR1 mitochondrial fission regulator 1 -2.51459
PMFBP1 polyamine modulated factor 1 binding protein 1 -2.48249
CHD7 chromodomain helicase DNA binding protein 7 -2.45248
EID2B EP300 interacting inhibitor of differentiation 2B -2.432
RECQL5 RecQ protein-like 5 -2.41979
RBL1 retinoblastoma-like 1 -2.40776
COLGALT1 collagen beta(1-O)galactosyltransferase 1 -2.40776
ANKAR ankyrin and armadillo repeat containing -2.39258
ONECUT1 one cut homeobox 1 -2.38838
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -2.38514
BLM Bloom syndrome, RecQ helicase-like -2.38514
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) -2.38282
ISCU iron-sulfur cluster assembly enzyme -2.37064
HSF1 heat shock transcription factor 1 -2.36644
MBLAC2 metallo-beta-lactamase domain containing 2 -2.35338
TTC28 tetratricopeptide repeat domain 28 -2.33915
EFCAB6 EF-hand calcium binding domain 6 -2.33815
CCDC85C coiled-coil domain containing 85C -2.33619
PLXNA3 plexin A3 -2.33407
NRIP2 nuclear receptor interacting protein 2 -2.3182
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -2.3182
TBC1D2B TBC1 domain family, member 2B -2.3174
TRIM36 tripartite motif containing 36 -2.31547
CCND2 cyclin D2 -2.30337
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 -2.30337
KITLG KIT ligand -2.29531
ZNF296 zinc finger protein 296 -2.29159
MTERF2 mitochondrial transcription termination factor 2 -2.28121
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 -2.28121
ZNG1E Zn regulated GTPase metalloprotein activator 1E -2.27889
EBPL emopamil binding protein-like -2.26246
PCBP1 poly(rC) binding protein 1 -2.25831
PSD3 pleckstrin and Sec7 domain containing 3 -2.25831
SUCO SUN domain containing ossification factor -2.2302
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -2.22419
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -2.20833
TRPC4 transient receptor potential cation channel, subfamily C, member 4 -2.1803
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -2.1803
GRTP1 growth hormone regulated TBC protein 1 -2.17434
NAV1 neuron navigator 1 -2.14404
SWI5 SWI5 recombination repair homolog (yeast) -2.11768
ZNF746 zinc finger protein 746 -2.10136
CTDNEP1 CTD nuclear envelope phosphatase 1 -2.09383
PDE5A phosphodiesterase 5A, cGMP-specific -2.09237
GLS2 glutaminase 2 (liver, mitochondrial) -2.08691
ANKRD13A ankyrin repeat domain 13A -2.08371
ZNF37A zinc finger protein 37A -2.07908
LIPG lipase, endothelial -2.06914
SIK1 salt-inducible kinase 1 -2.06674
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -2.06189
TMEM41B transmembrane protein 41B -2.05319
GOLGA2 golgin A2 -2.05319
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -2.04169
ADAR adenosine deaminase, RNA-specific -2.03467
ANKRD26 ankyrin repeat domain 26 -2.02948
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -2.02948
AFTPH aftiphilin -2.01743
NUP133 nucleoporin 133kDa -2.01508
TK2 thymidine kinase 2, mitochondrial -2.00704
CPAP centrosome assembly and centriole elongation protein -2.00347
PRRT3 proline-rich transmembrane protein 3 -2.00006
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) -2.00006
IL7 interleukin 7 -2.00006