SHISA4 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description shisa family member 4 (NCBI Entrez Gene Database, 149345)
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Genes

332 genes differentially expressed following the SHISA4 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
AOC3 amine oxidase, copper containing 3 2.41088
CDHR5 cadherin-related family member 5 2.41088
SPMIP7 sperm microtubule inner protein 7 2.41088
TSNAXIP1 translin-associated factor X interacting protein 1 2.41088
CEACAM16 carcinoembryonic antigen-related cell adhesion molecule 16 2.41088
CCDC175 coiled-coil domain containing 175 2.41088
MMD2 monocyte to macrophage differentiation-associated 2 2.41088
TNNI1 troponin I type 1 (skeletal, slow) 2.41088
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 2.4056
THAP5 THAP domain containing 5 2.4056
PKP1 plakophilin 1 2.4056
CASP4 caspase 4, apoptosis-related cysteine peptidase 2.4056
AZGP1 alpha-2-glycoprotein 1, zinc-binding 2.4056
OSR2 odd-skipped related transciption factor 2 2.4056
ARHGAP36 Rho GTPase activating protein 36 2.4056
CFHR3 complement factor H-related 3 2.4056
OR52A5 olfactory receptor, family 52, subfamily A, member 5 2.4056
RAI2 retinoic acid induced 2 2.4056
TMPRSS11A transmembrane protease, serine 11A 2.4056
HRH1 histamine receptor H1 2.4056
CD274 CD274 molecule 2.4056
NAPSA napsin A aspartic peptidase 2.4056
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 2.4056
CARD18 caspase recruitment domain family, member 18 2.4056
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 2.4056
PIWIL1 piwi-like RNA-mediated gene silencing 1 2.4056
SLC26A7 solute carrier family 26 (anion exchanger), member 7 2.4056
FNDC7 fibronectin type III domain containing 7 2.4056
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 2.4056
TAL2 T-cell acute lymphocytic leukemia 2 2.4056
MAGED4 melanoma antigen family D4 2.4056
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.4056
TMEM121 transmembrane protein 121 2.4056
NPIPA7 nuclear pore complex interacting protein family, member A7 2.4056
GNRHR gonadotropin-releasing hormone receptor 2.4056
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) 2.4056
DAAM2 dishevelled associated activator of morphogenesis 2 2.4056
IL2RA interleukin 2 receptor, alpha 2.4056
TAS2R10 taste receptor, type 2, member 10 2.4056
PRDM16 PR domain containing 16 2.4056
CAPS calcyphosine 2.4056
PRSS36 protease, serine, 36 2.4056
F2 coagulation factor II (thrombin) 2.4056
ANKRD34A ankyrin repeat domain 34A 2.4056
GCKR glucokinase (hexokinase 4) regulator 2.4056
TPSD1 tryptase delta 1 2.4056
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.4056
FSCN2 fascin actin-bundling protein 2, retinal 2.4056
MS4A14 membrane-spanning 4-domains, subfamily A, member 14 2.4056
UBA7 ubiquitin-like modifier activating enzyme 7 2.4056
GLRA3 glycine receptor, alpha 3 2.4056
PSCA prostate stem cell antigen 2.4056
CRH corticotropin releasing hormone 2.4056
ZNF354A zinc finger protein 354A 2.4056
MRC1 mannose receptor, C type 1 2.4056
SCARA5 scavenger receptor class A, member 5 2.4056
LY6S lymphocyte antigen 6 family member S 2.4056
GBP1 guanylate binding protein 1, interferon-inducible 2.4056
UNC93A unc-93 homolog A (C. elegans) 2.4056
MCHR1 melanin-concentrating hormone receptor 1 2.4056
PROP1 PROP paired-like homeobox 1 2.4056
MGAT4D MGAT4 family, member D 2.4056
OR2T8 olfactory receptor, family 2, subfamily T, member 8 2.4056
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 2.4056
ADRB1 adrenoceptor beta 1 2.4056
TMEM40 transmembrane protein 40 2.4056
CLDN2 claudin 2 2.4056
ANGPTL8 angiopoietin like 8 2.4056
ALPG alkaline phosphatase, germ cell 2.4056
EXOC1L exocyst complex component 1 like 2.4056
C8ORF90 chromosome 8 open reading frame 90 2.4056
LOC124903233 uncharacterized LOC124903233 2.4056
GLYATL1B glycine-N-acyltransferase like 1B 2.4056
TEX13C TEX13 family member C 2.4056
H2BW1 H2B.W histone 1 2.4056
DUSP29 dual specificity phosphatase 29 2.4056
DIPK1C divergent protein kinase domain 1C 2.4056
JAML junction adhesion molecule like 2.4056
SEPTIN9 septin 9 2.4056
HSPA6 heat shock 70kDa protein 6 (HSP70B') 2.4056
MYL10 myosin, light chain 10, regulatory 2.4056
TSPAN5 tetraspanin 5 2.4056
RUNX3 runt-related transcription factor 3 2.4056
IL4 interleukin 4 2.4056
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 2.4056
NPIPB9 nuclear pore complex interacting protein family, member B9 2.4056
CXCL16 chemokine (C-X-C motif) ligand 16 2.4056
C3ORF80 chromosome 3 open reading frame 80 2.4056
NXPE4 neurexophilin and PC-esterase domain family, member 4 2.4056
NXPE2 neurexophilin and PC-esterase domain family, member 2 2.4056
ODAD1 outer dynein arm docking complex subunit 1 2.4056
KLHL33 kelch-like family member 33 2.4056
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 2.4056
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 2.4056
GPR37L1 G protein-coupled receptor 37 like 1 2.4056
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 2.4056
ASIC3 acid sensing (proton gated) ion channel 3 2.4056
PGA5 pepsinogen 5, group I (pepsinogen A) 2.4056
SAA2 serum amyloid A2 2.4056
SASH3 SAM and SH3 domain containing 3 2.4056
SBSN suprabasin 2.4056
CELA2A chymotrypsin-like elastase family, member 2A 2.4056
NR0B1 nuclear receptor subfamily 0, group B, member 1 2.4056
CCR7 chemokine (C-C motif) receptor 7 2.4056
PCDHA8 protocadherin alpha 8 2.4056
WNT7B wingless-type MMTV integration site family, member 7B 2.4056
WNT2B wingless-type MMTV integration site family, member 2B 2.4056
FBXO47 F-box protein 47 2.4056
TMIGD3 transmembrane and immunoglobulin domain containing 3 2.4056
C9ORF57 chromosome 9 open reading frame 57 2.4056
PRRX1 paired related homeobox 1 2.4056
CROCC2 ciliary rootlet coiled-coil, rootletin family member 2 2.4056
TTC16 tetratricopeptide repeat domain 16 2.4056
CARNS1 carnosine synthase 1 2.4056
PRPH peripherin 2.4056
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 2.4056
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 2.4056
RNF222 ring finger protein 222 2.4056
WFDC10A WAP four-disulfide core domain 10A 2.4056
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 2.4056
SVOP SV2 related protein homolog (rat) 2.4056
RHAG Rh-associated glycoprotein 2.4056
FHIT fragile histidine triad 2.4056
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 2.4056
CATIP ciliogenesis associated TTC17 interacting protein 2.4056
C8ORF89 chromosome 8 open reading frame 89 2.4056
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 2.4056
AGXT2 alanine--glyoxylate aminotransferase 2 2.4056
LMOD2 leiomodin 2 (cardiac) 2.4056
FAM177B family with sequence similarity 177, member B 2.4056
BPIFB1 BPI fold containing family B, member 1 2.4056
TAT tyrosine aminotransferase 2.4056
CXCR5 chemokine (C-X-C motif) receptor 5 2.4056
CXCR4 chemokine (C-X-C motif) receptor 4 2.4056
AQP6 aquaporin 6, kidney specific 2.4056
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 2.4056
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2 2.4056
CNTF ciliary neurotrophic factor 2.4056
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.4056
FNDC8 fibronectin type III domain containing 8 2.4056
RPA4 replication protein A4, 30kDa 2.4056
HGFAC HGF activator 2.4056
PHOSPHO1 phosphatase, orphan 1 2.4056
TBX1 T-box 1 2.4056
TPH1 tryptophan hydroxylase 1 2.4056
SMCO3 single-pass membrane protein with coiled-coil domains 3 2.4056
FAM81B family with sequence similarity 81, member B 2.4056
NMBR neuromedin B receptor 2.4056
GSC2 goosecoid homeobox 2 2.4056
PDCD1LG2 programmed cell death 1 ligand 2 2.4056
NPR3 natriuretic peptide receptor 3 2.4056
R3HDML R3H domain containing-like 2.4056
PITX3 paired-like homeodomain 3 2.4056
KLHL10 kelch-like family member 10 2.4056
FAIM2 Fas apoptotic inhibitory molecule 2 2.4056
THSD1 thrombospondin, type I, domain containing 1 2.4056
PHACTR3 phosphatase and actin regulator 3 2.4056
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 2.4056
RTP4 receptor (chemosensory) transporter protein 4 2.4056
HAND1 heart and neural crest derivatives expressed 1 2.4056
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 2.4056
GOLGA8T golgin A8 family, member T 2.4056
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 2.4056
TMEM52B transmembrane protein 52B 2.4056
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.4056
IL9R interleukin 9 receptor 2.4056
THEM5 thioesterase superfamily member 5 2.4056
FGG fibrinogen gamma chain 2.4056
AICDA activation-induced cytidine deaminase 2.4056
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 2.4056
C10ORF90 chromosome 10 open reading frame 90 2.4056
SLC22A31 solute carrier family 22, member 31 2.4056
CISH cytokine inducible SH2-containing protein 2.4056
GREM1 gremlin 1, DAN family BMP antagonist 2.4056
PF4V1 platelet factor 4 variant 1 2.4056
IRX5 iroquois homeobox 5 2.4056
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.4056
HMGB4 high mobility group box 4 2.4056
ASCL1 achaete-scute family bHLH transcription factor 1 2.4056
NLRP2 NLR family, pyrin domain containing 2 2.4056
LPO lactoperoxidase 2.4056
POPDC2 popeye domain containing 2 2.4056
GRID2 glutamate receptor, ionotropic, delta 2 2.40411
CAMLG calcium modulating ligand 2.40411
CHURC1 churchill domain containing 1 2.35892
TJP2 tight junction protein 2 2.35374
ZNF221 zinc finger protein 221 2.31916
LRRTM1 leucine rich repeat transmembrane neuronal 1 2.31916
ZNF429 zinc finger protein 429 2.3021
PPP2R2D protein phosphatase 2, regulatory subunit B, delta 2.29226
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5 2.28329
PNMA3 paraneoplastic Ma antigen 3 2.28329
ARHGAP32 Rho GTPase activating protein 32 2.28329
SKIL SKI-like proto-oncogene 2.28329
MSI2 musashi RNA-binding protein 2 2.28329
SACK1A scaffolding CK1 anchoring protein A 2.28139
WDHD1 WD repeat and HMG-box DNA binding protein 1 2.26071
YME1L1 YME1-like 1 ATPase 2.25258
HMSD histocompatibility (minor) serpin domain containing 2.20811
CASP6 caspase 6, apoptosis-related cysteine peptidase 2.20422
SLC29A4 solute carrier family 29 (equilibrative nucleoside transporter), member 4 2.19883
GRIK2 glutamate receptor, ionotropic, kainate 2 2.17544
RNASEK ribonuclease, RNase K 2.15784
TCEAL4 transcription elongation factor A (SII)-like 4 2.14208
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 2.14074
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 2.11913
THEM4 thioesterase superfamily member 4 2.10774
RPL24 ribosomal protein L24 2.09891
KIF24 kinesin family member 24 2.09891
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 2.09129
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 2.09109
NCOA4 nuclear receptor coactivator 4 2.08955
P3H2 prolyl 3-hydroxylase 2 2.06631
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 2.06397
RMDN1 regulator of microtubule dynamics 1 2.06171
PPP1R17 protein phosphatase 1, regulatory subunit 17 2.05311
CHMP4B charged multivesicular body protein 4B 2.04211
OSTF1 osteoclast stimulating factor 1 2.03811
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2.02948
SOGA3 SOGA family member 3 2.02131
NRXN3 neurexin 3 2.01847
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.01847
CHSY1 chondroitin sulfate synthase 1 2.01798
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 2.01495
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 2.00701
PLXDC2 plexin domain containing 2 2.00301

decreased expression

Symbol Name Standardized Value
EGLN3 egl-9 family hypoxia-inducible factor 3 -2.4056
WSCD2 WSC domain containing 2 -2.4056
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) -2.4056
IL20RA interleukin 20 receptor, alpha -2.4056
FAM167B family with sequence similarity 167, member B -2.4056
HTRA3 HtrA serine peptidase 3 -2.4056
INSR insulin receptor -2.4056
GMDS GDP-mannose 4,6-dehydratase -2.4056
TP53TG5 TP53 target 5 -2.4056
DHRS7B dehydrogenase/reductase (SDR family) member 7B -2.4056
KAT2A K(lysine) acetyltransferase 2A -2.4056
NR1I2 nuclear receptor subfamily 1, group I, member 2 -2.4056
GPR161 G protein-coupled receptor 161 -2.4056
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B -2.4056
GLDN gliomedin -2.4056
PFN2 profilin 2 -2.4056
UNC13D unc-13 homolog D (C. elegans) -2.4056
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -2.4056
WDR91 WD repeat domain 91 -2.4056
CENATAC centrosomal AT-AC splicing factor -2.4056
BSG basigin (Ok blood group) -2.4056
SCN2A sodium channel, voltage gated, type II alpha subunit -2.4056
KCNT2 potassium channel, sodium activated subfamily T, member 2 -2.4056
ARRB2 arrestin, beta 2 -2.36843
PAPOLG poly(A) polymerase gamma -2.35374
LRRC39 leucine rich repeat containing 39 -2.35374
AOAH acyloxyacyl hydrolase (neutrophil) -2.34226
ERCC4 excision repair cross-complementation group 4 -2.30391
MYO3A myosin IIIA -2.29557
HLF hepatic leukemia factor -2.28329
RABL2A RAB, member of RAS oncogene family-like 2A -2.28329
ZNF43 zinc finger protein 43 -2.28329
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9 -2.28329
CPLX4 complexin 4 -2.28329
C1ORF146 chromosome 1 open reading frame 146 -2.28329
OC90 otoconin 90 -2.28329
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit -2.28329
SLC46A2 solute carrier family 46, member 2 -2.28329
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 -2.28329
CTRL chymotrypsin-like -2.28329
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime -2.28329
MOGAT3 monoacylglycerol O-acyltransferase 3 -2.28329
TMEM215 transmembrane protein 215 -2.28329
POM121L2 POM121 transmembrane nucleoporin-like 2 -2.28329
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 -2.28329
CRHR1 corticotropin releasing hormone receptor 1 -2.28329
XK X-linked Kx blood group -2.28329
TRHR thyrotropin-releasing hormone receptor -2.28329
FBXO41 F-box protein 41 -2.28329
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -2.28329
KY kyphoscoliosis peptidase -2.28329
WNT2 wingless-type MMTV integration site family member 2 -2.28329
ANKRD63 ankyrin repeat domain 63 -2.28329
RAB40C RAB40C, member RAS oncogene family -2.28329
NPPA natriuretic peptide A -2.28329
ADRA1A adrenoceptor alpha 1A -2.28329
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3 -2.28329
CD48 CD48 molecule -2.28329
VMO1 vitelline membrane outer layer 1 homolog (chicken) -2.28329
TIMD4 T-cell immunoglobulin and mucin domain containing 4 -2.28329
KIRREL2 kin of IRRE like 2 (Drosophila) -2.28233
TRAK2 trafficking protein, kinesin binding 2 -2.27259
GPR162 G protein-coupled receptor 162 -2.27062
ADGRG3 adhesion G protein-coupled receptor G3 -2.27062
TTC21B tetratricopeptide repeat domain 21B -2.23633
PBRM1 polybromo 1 -2.23387
MIEF2 mitochondrial elongation factor 2 -2.22918
TIMP4 TIMP metallopeptidase inhibitor 4 -2.22918
ZFP82 ZFP82 zinc finger protein -2.22004
CCNP cyclin P -2.20811
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -2.20303
NRN1L neuritin 1-like -2.20012
AIG1 androgen-induced 1 -2.16178
GPR156 G protein-coupled receptor 156 -2.14177
MAP4 microtubule-associated protein 4 -2.14177
DEGS2 delta(4)-desaturase, sphingolipid 2 -2.13896
TM7SF2 transmembrane 7 superfamily member 2 -2.12997
XKR7 XK, Kell blood group complex subunit-related family, member 7 -2.12816
PPP1R12A protein phosphatase 1, regulatory subunit 12A -2.12107
FBXW9 F-box and WD repeat domain containing 9 -2.10182
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 -2.09891
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta -2.09891
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.09529
TNPO2 transportin 2 -2.09529
PIKFYVE phosphoinositide kinase, FYVE finger containing -2.09109
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta -2.08955
EPSTI1 epithelial stromal interaction 1 (breast) -2.08665
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) -2.0844
MRPS9 mitochondrial ribosomal protein S9 -2.0844
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -2.07623
DUSP7 dual specificity phosphatase 7 -2.07394
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 -2.06631
TP53BP2 tumor protein p53 binding protein 2 -2.06397
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) -2.06171
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -2.05755
SNED1 sushi, nidogen and EGF-like domains 1 -2.05135
ZNF182 zinc finger protein 182 -2.05135
BMP6 bone morphogenetic protein 6 -2.0489
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 -2.04335
SHROOM2 shroom family member 2 -2.04
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase -2.02734
PDGFRL platelet-derived growth factor receptor-like -2.02131
NAP1L2 nucleosome assembly protein 1-like 2 -2.00301
CDK12 cyclin-dependent kinase 12 -2.00301
LRRC20 leucine rich repeat containing 20 -2.00301
ERLEC1 endoplasmic reticulum lectin 1 -2.00301