SHISA5 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description shisa family member 5|This gene encodes a member of the shisa family. The encoded protein is localized to the endoplasmic reticulum, and together with p53 induces apoptosis in a caspase-dependent manner. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] (NCBI Entrez Gene Database, 51246)
External Link https://ncbi.nlm.nih.gov/gene/51246
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Genes

498 genes differentially expressed following the SHISA5 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCL12 chemokine (C-X-C motif) ligand 12 0.017922
S100A9 S100 calcium binding protein A9 0.0175604
MX1 MX dynamin-like GTPase 1 0.0154296
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.0150985
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0148298
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.0148157
S100A8 S100 calcium binding protein A8 0.0142605
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0140425
LCN2 lipocalin 2 0.0135301
PDZK1IP1 PDZK1 interacting protein 1 0.0121273
IFI44 interferon-induced protein 44 0.0120873
CXCL14 chemokine (C-X-C motif) ligand 14 0.0116335
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.0116201
IFI44L interferon-induced protein 44-like 0.0115043
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.0113329
ISG15 ISG15 ubiquitin-like modifier 0.0112963
C3ORF14 chromosome 3 open reading frame 14 0.011263
RSAD2 radical S-adenosyl methionine domain containing 2 0.011202
PI3 peptidase inhibitor 3, skin-derived 0.0111825
S100A7 S100 calcium binding protein A7 0.0111342
ANK2 ankyrin 2, neuronal 0.0107625
TNIP1 TNFAIP3 interacting protein 1 0.0107218
XAF1 XIAP associated factor 1 0.0103412
MAL mal, T-cell differentiation protein 0.0103353
PEG3 paternally expressed 3 0.0102841
G0S2 G0/G1 switch 2 0.0102412
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0101058
RRAGD Ras-related GTP binding D 0.0100763
OLFML3 olfactomedin-like 3 0.010061
ARMCX1 armadillo repeat containing, X-linked 1 0.0100208
PLS3 plastin 3 0.00992831
IFITM1 interferon induced transmembrane protein 1 0.00978242
GAS1 growth arrest-specific 1 0.00972288
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00968498
SRPX sushi-repeat containing protein, X-linked 0.00965324
CXCL8 chemokine (C-X-C motif) ligand 8 0.00962038
CFI complement factor I 0.00962015
TUBB2B tubulin, beta 2B class IIb 0.00960529
LGALS13 lectin, galactoside-binding, soluble, 13 0.00956301
THBS2 thrombospondin 2 0.00952698
MX2 MX dynamin-like GTPase 2 0.00937166
PNMA2 paraneoplastic Ma antigen 2 0.00936738
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00936347
CRABP2 cellular retinoic acid binding protein 2 0.0093017
NREP neuronal regeneration related protein 0.00918499
TMEM45A transmembrane protein 45A 0.00915325
IFI27 interferon, alpha-inducible protein 27 0.00905031
DHCR24 24-dehydrocholesterol reductase 0.00902755
IFITM2 interferon induced transmembrane protein 2 0.00899478
GPX3 glutathione peroxidase 3 0.00897172
DCN decorin 0.00893584
PITX3 paired-like homeodomain 3 0.008915
PROM1 prominin 1 0.00881007
SLPI secretory leukocyte peptidase inhibitor 0.00878759
NIBAN1 niban apoptosis regulator 1 0.00874855
ECM1 extracellular matrix protein 1 0.00871663
RNF144A ring finger protein 144A 0.00871583
THBS4 thrombospondin 4 0.00867297
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00864097
CRABP1 cellular retinoic acid binding protein 1 0.00861907
CD200 CD200 molecule 0.00859877
NPTX2 neuronal pentraxin II 0.00857908
JPT1 Jupiter microtubule associated homolog 1 0.00850189
BEX4 brain expressed, X-linked 4 0.0084083
FGFBP1 fibroblast growth factor binding protein 1 0.00835313
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00834141
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00832041
ASS1 argininosuccinate synthase 1 0.00830845
DPYSL2 dihydropyrimidinase-like 2 0.00828288
SVIL supervillin 0.00827632
PDLIM2 PDZ and LIM domain 2 (mystique) 0.00826138
SELL selectin L 0.0081137
LAMP5 lysosomal-associated membrane protein family, member 5 0.00810348
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00810149
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0080961
P3H2 prolyl 3-hydroxylase 2 0.0080461
SFRP1 secreted frizzled-related protein 1 0.00796223
ZDHHC6 zinc finger, DHHC-type containing 6 0.00795844
MOXD1 monooxygenase, DBH-like 1 0.00791444
PTGIS prostaglandin I2 (prostacyclin) synthase 0.00781893
PXDN peroxidasin 0.00780427
IL1RN interleukin 1 receptor antagonist 0.00779751
C7 complement component 7 0.00779063
SALL2 spalt-like transcription factor 2 0.0077893
IFITM3 interferon induced transmembrane protein 3 0.0077625
NSG1 neuron specific gene family member 1 0.00772311
ADD3 adducin 3 (gamma) 0.00756169
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.00749557
ACAT2 acetyl-CoA acetyltransferase 2 0.00748862
FXYD6 FXYD domain containing ion transport regulator 6 0.00748763
ADGRL2 adhesion G protein-coupled receptor L2 0.00748201
FMO2 flavin containing monooxygenase 2 (non-functional) 0.00746997
BAMBI BMP and activin membrane-bound inhibitor 0.00740586
SSPN sarcospan 0.00737578
XPO7 exportin 7 0.00735802
CELF2 CUGBP, Elav-like family member 2 0.00733985
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.0072188
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 0.00719264
SFRP4 secreted frizzled-related protein 4 0.00712889
CLTB clathrin, light chain B 0.00707856
CLDN10 claudin 10 0.00706381
CSTA cystatin A (stefin A) 0.00701348
ATF3 activating transcription factor 3 0.00699618
PRELP proline/arginine-rich end leucine-rich repeat protein 0.00699035
CHRDL1 chordin-like 1 0.00698406
S100A10 S100 calcium binding protein A10 0.00697821
MSRB2 methionine sulfoxide reductase B2 0.0069705
WISP2 WNT1 inducible signaling pathway protein 2 0.00696795
SP110 SP110 nuclear body protein 0.00695917
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00695882
FHL1 four and a half LIM domains 1 0.00693679
TP53I3 tumor protein p53 inducible protein 3 0.00691906
KLF2 Kruppel-like factor 2 0.00688794
PDGFRL platelet-derived growth factor receptor-like 0.00688026
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00683157
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00679513
AEBP1 AE binding protein 1 0.00679407
OASL 2'-5'-oligoadenylate synthetase-like 0.00679066
FBLN5 fibulin 5 0.00676483
TADA2A transcriptional adaptor 2A 0.00674531
RGS4 regulator of G-protein signaling 4 0.00671817
ACAA2 acetyl-CoA acyltransferase 2 0.00670389
SORBS1 sorbin and SH3 domain containing 1 0.00669851
FAR2 fatty acyl CoA reductase 2 0.00668945
ALOX5 arachidonate 5-lipoxygenase 0.00668172
TMSB15A thymosin beta 15a 0.00666963
FST follistatin 0.00666311
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.00665613
S100A12 S100 calcium binding protein A12 0.00665496
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00663879
CSRP2 cysteine and glycine-rich protein 2 0.0066276
CD300A CD300a molecule 0.00662747
IFI6 interferon, alpha-inducible protein 6 0.00662128
SORBS3 sorbin and SH3 domain containing 3 0.00661127
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00661059
MFAP4 microfibrillar-associated protein 4 0.00659903
CLIC5 chloride intracellular channel 5 0.00659273
PGAM1 phosphoglycerate mutase 1 (brain) 0.00658529
TRIM22 tripartite motif containing 22 0.00657846
FAM171A1 family with sequence similarity 171, member A1 0.00655309
DEFB1 defensin, beta 1 0.00652996
CCL20 chemokine (C-C motif) ligand 20 0.00650954
PCOLCE procollagen C-endopeptidase enhancer 0.00649563
TWIST1 twist family bHLH transcription factor 1 0.00646285
ANXA6 annexin A6 0.00636867
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00636284
TRIM29 tripartite motif containing 29 0.00632778
AK4 adenylate kinase 4 0.00631624
CCNG1 cyclin G1 0.0063155
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.00631199
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00630414
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00630306
OPTN optineurin 0.00629526
TCEAL2 transcription elongation factor A (SII)-like 2 0.00629376
MAOB monoamine oxidase B 0.00627156
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00626596
IRF7 interferon regulatory factor 7 0.00625621
S100A14 S100 calcium binding protein A14 0.00624969
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00624961
AOX1 aldehyde oxidase 1 0.00624833
LST1 leukocyte specific transcript 1 0.00620453
CXCL6 chemokine (C-X-C motif) ligand 6 0.00620422
PYCARD PYD and CARD domain containing 0.00620199
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00618783
ASPN asporin 0.00618633
IL32 interleukin 32 0.00618007
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00616721
SMAGP small cell adhesion glycoprotein 0.00615423
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00615184
LMCD1 LIM and cysteine-rich domains 1 0.00614672
TFF1 trefoil factor 1 0.0061255
TNS1 tensin 1 0.0061227
TSPYL5 TSPY-like 5 0.00611656
LY6D lymphocyte antigen 6 complex, locus D 0.00610813
CRYAB crystallin, alpha B 0.0060907
KRT5 keratin 5, type II 0.00609024
LPIN1 lipin 1 0.00608438
CALML3 calmodulin-like 3 0.00606131
LTB lymphotoxin beta (TNF superfamily, member 3) 0.00606108
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00604286
CFB complement factor B 0.00603282
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 0.00603095
MDFIC MyoD family inhibitor domain containing 0.00603064
TFPI2 tissue factor pathway inhibitor 2 0.00602673
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.00601339
DNTT DNA nucleotidylexotransferase 0.00597837
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.00597432
TUBA1A tubulin, alpha 1a 0.00593673
VCAN versican 0.00592957
GOLGA8H golgin A8 family, member H 0.00592346
TARP TCR gamma alternate reading frame protein 0.00587996
DPYSL3 dihydropyrimidinase-like 3 0.00587503
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00586968
MFAP2 microfibrillar-associated protein 2 0.00586656
MN1 meningioma (disrupted in balanced translocation) 1 0.00584175
QPRT quinolinate phosphoribosyltransferase 0.00584155
CD3D CD3d molecule, delta (CD3-TCR complex) 0.00583452
RBKS ribokinase 0.00582939
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00582546
CETN2 centrin, EF-hand protein, 2 0.00580214
PLK2 polo-like kinase 2 0.00580055
LY86 lymphocyte antigen 86 0.0057941
TSPAN7 tetraspanin 7 0.00577631
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00577367
GSTA4 glutathione S-transferase alpha 4 0.00576401
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00575487
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.00574817
ICAM2 intercellular adhesion molecule 2 0.00574579
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.00574353
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00574101
PELI2 pellino E3 ubiquitin protein ligase family member 2 0.00571025
MT1E metallothionein 1E 0.005676
TM4SF1 transmembrane 4 L six family member 1 0.00567448
PRKCQ protein kinase C, theta 0.00567441
MAP2K5 mitogen-activated protein kinase kinase 5 0.00567106
H1-10 H1.10 linker histone 0.00564312
TPM4 tropomyosin 4 0.0056205
SC5D sterol-C5-desaturase 0.00560872
LZTS3 leucine zipper, putative tumor suppressor family member 3 0.00558967
TSPAN3 tetraspanin 3 0.00558749
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.00558513
TAGLN transgelin 0.00558145
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00557122
PPL periplakin 0.00556773
PLBD1 phospholipase B domain containing 1 0.00556094
SCPEP1 serine carboxypeptidase 1 0.00555841
FZD4 frizzled class receptor 4 0.00555104
SLC43A3 solute carrier family 43, member 3 0.00554254
SPRR1B small proline-rich protein 1B 0.00553168
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.00553117
HTRA1 HtrA serine peptidase 1 0.00551752
IL2RG interleukin 2 receptor, gamma 0.00547251
TDRD7 tudor domain containing 7 0.0054725
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.00546695
ISG20 interferon stimulated exonuclease gene 20kDa 0.00545818
NID2 nidogen 2 (osteonidogen) 0.00545222
FLNA filamin A, alpha 0.00544974
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00544627
PDLIM3 PDZ and LIM domain 3 0.00544575
AKAP12 A kinase (PRKA) anchor protein 12 0.00544258
BIN1 bridging integrator 1 0.00544096
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.00542925
FADS1 fatty acid desaturase 1 0.00541987
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00541662
FXYD1 FXYD domain containing ion transport regulator 1 0.00540955
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00540286
CEMIP cell migration inducing protein, hyaluronan binding 0.00540141
SPRR1A small proline-rich protein 1A 0.00538736
BEX1 brain expressed, X-linked 1 0.00538534
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.00538029

decreased expression

Symbol Name Standardized Value
TM9SF3 transmembrane 9 superfamily member 3 -0.0149253
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0134299
MAP7 microtubule-associated protein 7 -0.0121572
MET MET proto-oncogene, receptor tyrosine kinase -0.0104113
ADAMDEC1 ADAM-like, decysin 1 -0.0099469
ZBTB38 zinc finger and BTB domain containing 38 -0.00955967
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00924351
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00905719
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00859204
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00858376
MAGEA3 melanoma antigen family A3 -0.00836619
ADAM9 ADAM metallopeptidase domain 9 -0.00827615
CLU clusterin -0.00827471
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00827141
RGCC regulator of cell cycle -0.0082571
RAB40B RAB40B, member RAS oncogene family -0.00825425
CD163 CD163 molecule -0.00822077
CHN1 chimerin 1 -0.00814093
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00813621
SCARB2 scavenger receptor class B, member 2 -0.00812563
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.0080912
ALCAM activated leukocyte cell adhesion molecule -0.00767747
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00744228
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.00743465
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.00741002
BTBD3 BTB (POZ) domain containing 3 -0.00737874
KIF5B kinesin family member 5B -0.0073298
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.00731838
GPM6A glycoprotein M6A -0.00731254
AMDHD2 amidohydrolase domain containing 2 -0.00726958
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00725559
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.00711406
GCLC glutamate-cysteine ligase, catalytic subunit -0.00709667
FOXF1 forkhead box F1 -0.00700841
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.00697345
MMP12 matrix metallopeptidase 12 -0.00694411
FUCA1 fucosidase, alpha-L- 1, tissue -0.00694329
SSX1 synovial sarcoma, X breakpoint 1 -0.00694213
FTH1 ferritin, heavy polypeptide 1 -0.00694072
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.00693941
UXT ubiquitously-expressed, prefoldin-like chaperone -0.00692024
KLF5 Kruppel-like factor 5 (intestinal) -0.00686831
ITGA6 integrin, alpha 6 -0.00685913
MTCL1 microtubule crosslinking factor 1 -0.00685026
BAD BCL2-associated agonist of cell death -0.00684987
RGS13 regulator of G-protein signaling 13 -0.00679103
SOX9 SRY (sex determining region Y)-box 9 -0.00678828
ERBIN erbb2 interacting protein -0.00668299
GPR88 G protein-coupled receptor 88 -0.0066258
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00662394
PRSS21 protease, serine, 21 (testisin) -0.00659094
SYNGR3 synaptogyrin 3 -0.00656469
TMEM259 transmembrane protein 259 -0.00655678
EFR3A EFR3 homolog A (S. cerevisiae) -0.00649196
PLPP2 phospholipid phosphatase 2 -0.00647917
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -0.00637412
SFTPB surfactant protein B -0.00635407
KRT81 keratin 81, type II -0.006249
SCRG1 stimulator of chondrogenesis 1 -0.00623825
DOCK9 dedicator of cytokinesis 9 -0.00619274
CPA3 carboxypeptidase A3 (mast cell) -0.00619121
PAX5 paired box 5 -0.0061771
SIRT3 sirtuin 3 -0.00616156
ZNF395 zinc finger protein 395 -0.00615683
PUF60 poly-U binding splicing factor 60KDa -0.00613803
HCRT hypocretin (orexin) neuropeptide precursor -0.00612231
TGFBI transforming growth factor, beta-induced, 68kDa -0.00609589
BRD2 bromodomain containing 2 -0.00604906
BRD4 bromodomain containing 4 -0.00604446
KRT7 keratin 7, type II -0.0060205
BIK BCL2-interacting killer (apoptosis-inducing) -0.00601789
C1QA complement component 1, q subcomponent, A chain -0.00593491
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00589385
PIP prolactin-induced protein -0.00587041
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.00585223
SNX13 sorting nexin 13 -0.0057807
HIST1H2AE histone cluster 1, H2ae -0.00577103
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00576459
NBPF10 neuroblastoma breakpoint family, member 10 -0.00575742
MRPL12 mitochondrial ribosomal protein L12 -0.00575607
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.00570925
C1QB complement component 1, q subcomponent, B chain -0.00568596
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00567437
CTTN cortactin -0.00564642
ADAM28 ADAM metallopeptidase domain 28 -0.00563163
SMAD6 SMAD family member 6 -0.00563145
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00562454
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00561159
LPPR1 lipid phosphate phosphatase-related protein type 1 -0.0055913
LRRC31 leucine rich repeat containing 31 -0.00556471
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00554678
MAGEA12 melanoma antigen family A12 -0.00554423
MRTFB myocardin related transcription factor B -0.00552975
GLUL glutamate-ammonia ligase -0.00552051
VWF von Willebrand factor -0.00550127
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00549284
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.00546267
CD1E CD1e molecule -0.00541326
SAC3D1 SAC3 domain containing 1 -0.00540531
MAGEB2 melanoma antigen family B2 -0.00539525
PBK PDZ binding kinase -0.00538877
EPAS1 endothelial PAS domain protein 1 -0.00537996
TPTE transmembrane phosphatase with tensin homology -0.00537946
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00537516
EZR ezrin -0.00530965
PAQR6 progestin and adipoQ receptor family member VI -0.00526837
ARL4A ADP-ribosylation factor-like 4A -0.00525296
PHACTR2 phosphatase and actin regulator 2 -0.0052255
PAWR PRKC, apoptosis, WT1, regulator -0.00522337
TMEM106B transmembrane protein 106B -0.00522038
ING2 inhibitor of growth family, member 2 -0.00518703
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00518324
TPSAB1 tryptase alpha/beta 1 -0.00516732
EREG epiregulin -0.00515609
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.005146
MID1 midline 1 -0.00513837
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.00512003
BCAS4 breast carcinoma amplified sequence 4 -0.00511219
TOX3 TOX high mobility group box family member 3 -0.00510984
OSBPL10 oxysterol binding protein-like 10 -0.00509614
CHIC2 cysteine-rich hydrophobic domain 2 -0.00508484
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -0.00507573
TENT4A terminal nucleotidyltransferase 4A -0.00506919
LIMS1 LIM and senescent cell antigen-like domains 1 -0.00506255
DHRS11 dehydrogenase/reductase (SDR family) member 11 -0.00503289
IL18 interleukin 18 -0.0050302
SH3GLB2 SH3-domain GRB2-like endophilin B2 -0.0050302
SLC30A10 solute carrier family 30, member 10 -0.0050264
ANO10 anoctamin 10 -0.00501332
PEX5 peroxisomal biogenesis factor 5 -0.00500907
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 -0.00499258
CLCN3 chloride channel, voltage-sensitive 3 -0.00499053
SNX11 sorting nexin 11 -0.0049889
HNMT histamine N-methyltransferase -0.00498584
SEH1L SEH1-like (S. cerevisiae) -0.00497892
CIAO3 cytosolic iron-sulfur assembly component 3 -0.00496512
PFDN2 prefoldin subunit 2 -0.00495389
GRB14 growth factor receptor-bound protein 14 -0.00492849
REPIN1 replication initiator 1 -0.00492583
CCDC47 coiled-coil domain containing 47 -0.00492162
SI sucrase-isomaltase (alpha-glucosidase) -0.00490776
HIPK2 homeodomain interacting protein kinase 2 -0.00487278
POU2AF1 POU class 2 associating factor 1 -0.00487001
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00486994
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00486025
ATP9A ATPase, class II, type 9A -0.00484402
MEST mesoderm specific transcript -0.0048414
UPK1B uroplakin 1B -0.00483786
ZBTB35 zinc finger and BTB domain containing 35 -0.00482735
OFD1 oral-facial-digital syndrome 1 -0.00481364
GFAP glial fibrillary acidic protein -0.00479323
XK X-linked Kx blood group -0.00479066
APOLD1 apolipoprotein L domain containing 1 -0.0047758
THAP12 THAP domain containing 12 -0.00477095
TPD52 tumor protein D52 -0.00476833
UBE2S ubiquitin-conjugating enzyme E2S -0.00476232
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.0047487
MARCHF6 membrane associated ring-CH-type finger 6 -0.00473181
CLCA1 chloride channel accessory 1 -0.00473085
CXCR5 chemokine (C-X-C motif) receptor 5 -0.00471618
NCAN neurocan -0.0047066
CFHR5 complement factor H-related 5 -0.00468295
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta -0.00467625
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 -0.00467185
TBC1D12 TBC1 domain family, member 12 -0.00465728
TWF1 twinfilin actin binding protein 1 -0.00465585
ZNF12 zinc finger protein 12 -0.00465082
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0046503
DSC1 desmocollin 1 -0.00464
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00463602
FOXF2 forkhead box F2 -0.00463582
PRMT3 protein arginine methyltransferase 3 -0.0046107
TSC22D1 TSC22 domain family, member 1 -0.00459934
FEM1B fem-1 homolog b (C. elegans) -0.00459812
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 -0.00459762
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -0.00459706
TKTL1 transketolase-like 1 -0.00458502
KRT20 keratin 20, type I -0.00458255
PTCH1 patched 1 -0.00458149
HNRNPR heterogeneous nuclear ribonucleoprotein R -0.00456806
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -0.00453385
PLPP3 phospholipid phosphatase 3 -0.00452944
PDCD6 programmed cell death 6 -0.00452668
CADM1 cell adhesion molecule 1 -0.00450407
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -0.0044823
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00448155
CBX1 chromobox homolog 1 -0.00447936
LEPROT leptin receptor overlapping transcript -0.00447549
DGKZ diacylglycerol kinase, zeta -0.00447535
CTSB cathepsin B -0.0044655
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -0.00446353
FGFR3 fibroblast growth factor receptor 3 -0.0044551
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00443693
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00442279
DLX5 distal-less homeobox 5 -0.00441901
SLC38A1 solute carrier family 38, member 1 -0.00441124
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00440697
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00440349
TSEN2 TSEN2 tRNA splicing endonuclease subunit -0.00440188
MAPK1 mitogen-activated protein kinase 1 -0.00437101
USP47 ubiquitin specific peptidase 47 -0.0043702
TFRC transferrin receptor -0.00435229
TRAF3 TNF receptor-associated factor 3 -0.00435213
EPHA4 EPH receptor A4 -0.00434848
YES1 YES proto-oncogene 1, Src family tyrosine kinase -0.00434828
ANO1 anoctamin 1, calcium activated chloride channel -0.00434576
GAS2L1 growth arrest-specific 2 like 1 -0.00434418
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.0043421
HELLS helicase, lymphoid-specific -0.00433061
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -0.00432519
ARID1A AT rich interactive domain 1A (SWI-like) -0.00432196
KLHDC2 kelch domain containing 2 -0.00431508
NNT nicotinamide nucleotide transhydrogenase -0.00430817
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00430719
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00430545
CD151 CD151 molecule (Raph blood group) -0.00427342
SH3BP4 SH3-domain binding protein 4 -0.00426191
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -0.00425924
CBX6 chromobox homolog 6 -0.00425645
DEFA5 defensin, alpha 5, Paneth cell-specific -0.00425578
KMT5A lysine methyltransferase 5A -0.00425428
GSR glutathione reductase -0.00425036
DGS2 DiGeorge syndrome/velocardiofacial syndrome complex 2 -0.00424726
ANKRD12 ankyrin repeat domain 12 -0.00424723
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -0.00424612
CHD4 chromodomain helicase DNA binding protein 4 -0.00421488
BDNF brain-derived neurotrophic factor -0.00421474
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.00421021
JCHAIN joining chain of multimeric IgA and IgM -0.00420704
HAL histidine ammonia-lyase -0.00420386
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -0.00420259
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -0.00420256
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.00419206
EIF5B eukaryotic translation initiation factor 5B -0.00418867
PBX1 pre-B-cell leukemia homeobox 1 -0.00418573
OLFML2B olfactomedin-like 2B -0.00417798
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -0.00417425
FIP1L1 factor interacting with PAPOLA and CPSF1 -0.00417375
TESK1 testis-specific kinase 1 -0.00416811
ITGB4 integrin, beta 4 -0.00415097
TMEM165 transmembrane protein 165 -0.00414925
MAGEA1 melanoma antigen family A1 -0.00414549
MYOF myoferlin -0.00414188
PID1 phosphotyrosine interaction domain containing 1 -0.00414064
FNDC3B fibronectin type III domain containing 3B -0.00413213
COL4A5 collagen, type IV, alpha 5 -0.00413105
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -0.00411507
NR1H3 nuclear receptor subfamily 1, group H, member 3 -0.00411191