SHOC1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description shortage in chiasmata 1 (NCBI Entrez Gene Database, 158401)
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Genes

333 genes differentially expressed following the SHOC1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CTRC chymotrypsin C (caldecrin) 3.15622
TKTL1 transketolase-like 1 3.15622
GRIA2 glutamate receptor, ionotropic, AMPA 2 3.15622
ASPA aspartoacylase 3.15622
GPR26 G protein-coupled receptor 26 3.15622
MYOM3 myomesin 3 3.15622
LYNX1 Ly6/neurotoxin 1 3.15622
ANKRD34A ankyrin repeat domain 34A 3.15622
FAM221B family with sequence similarity 221, member B 3.15622
PTGFR prostaglandin F receptor (FP) 3.15622
FSCN2 fascin actin-bundling protein 2, retinal 3.15622
SLC25A41 solute carrier family 25, member 41 3.15622
PEAR1 platelet endothelial aggregation receptor 1 3.15622
NOD2 nucleotide-binding oligomerization domain containing 2 3.15622
ALOX15 arachidonate 15-lipoxygenase 3.15622
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 3.15622
SPINK6 serine peptidase inhibitor, Kazal type 6 3.15622
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 3.15622
TRIM15 tripartite motif containing 15 3.15622
MUC6 mucin 6, oligomeric mucus/gel-forming 3.15622
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 3.15622
PCDHB9 protocadherin beta 9 3.15622
SLC35G5 solute carrier family 35, member G5 3.15622
SOX14 SRY (sex determining region Y)-box 14 3.15622
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 3.15622
PSCA prostate stem cell antigen 3.15622
SNAI2 snail family zinc finger 2 3.15622
EBI3 Epstein-Barr virus induced 3 3.15622
GRM6 glutamate receptor, metabotropic 6 3.15622
NPR3 natriuretic peptide receptor 3 3.15622
KRTAP13-2 keratin associated protein 13-2 3.15622
ZC2HC1B zinc finger, C2HC-type containing 1B 3.15622
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 3.15622
LPO lactoperoxidase 3.15622
CEACAM20 carcinoembryonic antigen-related cell adhesion molecule 20 3.15622
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 3.15622
SCIN scinderin 3.15622
FGF9 fibroblast growth factor 9 3.15622
FGF7 fibroblast growth factor 7 3.15622
TMEM89 transmembrane protein 89 3.15622
CCDC38 coiled-coil domain containing 38 3.15622
NPIPA8 nuclear pore complex interacting protein family, member A8 3.15622
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 3.15622
AVP arginine vasopressin 3.15622
LGALS2 lectin, galactoside-binding, soluble, 2 3.15622
HMX3 H6 family homeobox 3 3.15622
MAP2K3 mitogen-activated protein kinase kinase 3 3.15622
CFAP54 cilia and flagella associated 54 3.15622
FGF5 fibroblast growth factor 5 3.15622
ANGPTL7 angiopoietin-like 7 3.15622
SLC26A1 solute carrier family 26 (anion exchanger), member 1 3.15622
ADAMTSL4-AS2 ADAMTSL4 antisense RNA 2 3.15622
ERVW-1 endogenous retrovirus group W, member 1 3.15622
HAO2 hydroxyacid oxidase 2 (long chain) 3.15622
GBP6 guanylate binding protein family, member 6 3.15622
GBP3 guanylate binding protein 3 3.15622
ALX1 ALX homeobox 1 3.15622
PDF peptide deformylase (mitochondrial) 3.15622
C20ORF202 chromosome 20 open reading frame 202 3.15622
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 3.15622
CIMIP2B ciliary microtubule inner protein 2B 3.15622
MYZAP myocardial zonula adherens protein 3.15622
GOLGA6L7 golgin A6 family like 7 3.15622
H2BC1 H2B clustered histone 1 3.15622
H1-6 H1.6 linker histone, cluster member 3.15622
SAXO4 stabilizer of axonemal microtubules 4 3.15622
SMIM45 small integral membrane protein 45 3.15622
LHFPL7 LHFPL tetraspan subfamily member 7 3.15622
CFAP276 cilia and flagella associated protein 276 3.15622
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 3.15622
JAML junction adhesion molecule like 3.15622
LORICRIN loricrin cornified envelope precursor protein 3.15622
CPHXL2 cytoplasmic polyadenylated homeobox like 2 3.15622
TMEM275 transmembrane protein 275 3.15622
PWWP3B PWWP domain containing 3B 3.15622
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 3.15622
DOK7 docking protein 7 3.15622
TMEM229B transmembrane protein 229B 3.15622
LIPK lipase, family member K 3.15622
TAS2R31 taste receptor, type 2, member 31 3.15622
FPR1 formyl peptide receptor 1 3.15622
CES3 carboxylesterase 3 3.15622
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 3.15622
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 3.15622
SOX1 SRY (sex determining region Y)-box 1 3.15622
FGF21 fibroblast growth factor 21 3.15622
MAP3K7CL MAP3K7 C-terminal like 3.15622
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 3.15622
MIA melanoma inhibitory activity 3.15622
RASAL3 RAS protein activator like 3 3.15622
OR52E5 olfactory receptor, family 52, subfamily E, member 5 3.15622
DYNLRB2 dynein, light chain, roadblock-type 2 3.15622
GATA1 GATA binding protein 1 (globin transcription factor 1) 3.15622
CLEC6A C-type lectin domain family 6, member A 3.15622
DYNAP dynactin associated protein 3.15622
ASIC4 acid sensing (proton gated) ion channel family member 4 3.15622
FGFBP2 fibroblast growth factor binding protein 2 3.15622
OOSP1 oocyte secreted protein 1, pseudogene 3.15622
SASH3 SAM and SH3 domain containing 3 3.15622
TACR2 tachykinin receptor 2 3.15622
NPAP1 nuclear pore associated protein 1 3.15622
GPR12 G protein-coupled receptor 12 3.15622
COX7B2 cytochrome c oxidase subunit VIIb2 3.15622
MS4A8 membrane-spanning 4-domains, subfamily A, member 8 3.15622
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 3.15622
SLC22A24 solute carrier family 22, member 24 3.15622
ZEB1 zinc finger E-box binding homeobox 1 3.15622
SPATA9 spermatogenesis associated 9 3.15622
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3.15622
PRR36 proline rich 36 3.15622
ITGA10 integrin, alpha 10 3.15622
CASQ2 calsequestrin 2 (cardiac muscle) 3.15622
CDH12 cadherin 12, type 2 (N-cadherin 2) 3.15622
SV2B synaptic vesicle glycoprotein 2B 3.15622
TNR tenascin R 3.15622
SYNE3 spectrin repeat containing, nuclear envelope family member 3 3.15622
DCLK3 doublecortin-like kinase 3 3.15622
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 3.15622
TIGD3 tigger transposable element derived 3 3.15622
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 3.15622
NPFFR1 neuropeptide FF receptor 1 3.15622
C16ORF78 chromosome 16 open reading frame 78 3.15622
OCM oncomodulin 3.15622
CFAP61 cilia and flagella associated protein 61 3.15622
PLCL1 phospholipase C-like 1 3.15622
NYX nyctalopin 3.15622
MYADML2 myeloid-associated differentiation marker-like 2 3.15622
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 3.15622
LMX1B LIM homeobox transcription factor 1, beta 3.15622
PPP1R27 protein phosphatase 1, regulatory subunit 27 3.15622
LRRN4 leucine rich repeat neuronal 4 3.15622
TTC24 tetratricopeptide repeat domain 24 3.15622
ADRA2A adrenoceptor alpha 2A 3.15622
GOLGA8K golgin A8 family, member K 3.15622
TCAP titin-cap 3.15622
RGS4 regulator of G-protein signaling 4 3.15622
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 3.15622
KLF1 Kruppel-like factor 1 (erythroid) 3.15622
AMN amnion associated transmembrane protein 3.15622
PLD2 phospholipase D2 3.15622
OTOP1 otopetrin 1 3.15622
F13B coagulation factor XIII, B polypeptide 3.15622
UBXN10 UBX domain protein 10 3.15622
NCR3 natural cytotoxicity triggering receptor 3 3.15622
LHX2 LIM homeobox 2 3.15622
CFP complement factor properdin 3.15622
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) 3.15622
TMPRSS15 transmembrane protease, serine 15 3.15622
SLFN12L schlafen family member 12-like 3.15622
GRAP2 GRB2-related adaptor protein 2 3.15622
NUTM2A NUT family member 2A 3.15622
LAMP3 lysosomal-associated membrane protein 3 3.15622
TMPRSS13 transmembrane protease, serine 13 3.15622
RERGL RERG/RAS-like 3.15622
CHRM4 cholinergic receptor, muscarinic 4 3.15622
TSPAN32 tetraspanin 32 3.15622
BPIFA3 BPI fold containing family A, member 3 3.15622
PCDHGB1 protocadherin gamma subfamily B, 1 3.15622
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8 3.15622
MAPK11 mitogen-activated protein kinase 11 3.15622
KRTAP5-11 keratin associated protein 5-11 3.15622
TCEA3 transcription elongation factor A (SII), 3 3.15622
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 3.15622
TGM1 transglutaminase 1 3.15622
ENDOU endonuclease, polyU-specific 3.15622
NPPA natriuretic peptide A 3.15622
PRR15L proline rich 15-like 3.15622
FRMPD2 FERM and PDZ domain containing 2 3.15622
CNTF ciliary neurotrophic factor 3.15622
MST1 macrophage stimulating 1 3.04668
MYH2 myosin, heavy chain 2, skeletal muscle, adult 3.04668
FAM186B family with sequence similarity 186, member B 3.00869
REC8 REC8 meiotic recombination protein 2.94678
SDR42E2 short chain dehydrogenase/reductase family 42E, member 2 2.92226
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 2.66193
COPS9 COP9 signalosome subunit 9 2.64454
NBPF26 neuroblastoma breakpoint family, member 26 2.56746
ZNF428 zinc finger protein 428 2.54708
SEPHS2 selenophosphate synthetase 2 2.52887
DRC4 dynein regulatory complex subunit 4 2.52094
ZDHHC19 zinc finger, DHHC-type containing 19 2.51904
RCC2 regulator of chromosome condensation 2 2.45865
CFAP157 cilia and flagella associated protein 157 2.39168
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.38871
TNS4 tensin 4 2.38823
FGF23 fibroblast growth factor 23 2.38823
ZNF141 zinc finger protein 141 2.37953
DST dystonin 2.35518
INTS6 integrator complex subunit 6 2.34035
AKAP14 A kinase (PRKA) anchor protein 14 2.33334
MT1M metallothionein 1M 2.33334
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) 2.29819
S100Z S100 calcium binding protein Z 2.27986
RLN1 relaxin 1 2.27986
ASB13 ankyrin repeat and SOCS box containing 13 2.25786
SMYD5 SMYD family member 5 2.25786
GJC3 gap junction protein, gamma 3, 30.2kDa 2.25435
SORBS2 sorbin and SH3 domain containing 2 2.23905
CTH cystathionine gamma-lyase 2.20872
BCL2L2 BCL2-like 2 2.16615
BCL2L14 BCL2-like 14 (apoptosis facilitator) 2.1574
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 2.14372
TMEM150A transmembrane protein 150A 2.12977
KIAA1143 KIAA1143 2.12917
PIGS phosphatidylinositol glycan anchor biosynthesis, class S 2.08637
EXO5 exonuclease 5 2.08235
ARL3 ADP-ribosylation factor-like 3 2.07448
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 2.06805
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 2.06583
DENND11 DENN domain containing 11 2.06583
MCMDC2 minichromosome maintenance domain containing 2 2.06583
LRP2 low density lipoprotein receptor-related protein 2 2.06583
FBXO16 F-box protein 16 2.06082
MOXD1 monooxygenase, DBH-like 1 2.05875
PABPC4L poly(A) binding protein, cytoplasmic 4-like 2.0449
EDC3 enhancer of mRNA decapping 3 2.0449
TMEM86A transmembrane protein 86A 2.0449
SLC4A2 solute carrier family 4 (anion exchanger), member 2 2.0449
SFRP4 secreted frizzled-related protein 4 2.0449
ZNF804A zinc finger protein 804A 2.0449
SGCZ sarcoglycan, zeta 2.0449
NEMF nuclear export mediator factor 2.0425
TECPR2 tectonin beta-propeller repeat containing 2 2.02514
WDFY1 WD repeat and FYVE domain containing 1 2.01932
TRIM22 tripartite motif containing 22 2.0141
SLC39A10 solute carrier family 39 (zinc transporter), member 10 2.0141
NT5DC1 5'-nucleotidase domain containing 1 2.01311
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 2.00622
KLRG1 killer cell lectin-like receptor subfamily G, member 1 2.0061

decreased expression

Symbol Name Standardized Value
BPGM 2,3-bisphosphoglycerate mutase -3.15622
EDAR ectodysplasin A receptor -3.15622
NPNT nephronectin -3.15622
SPON2 spondin 2, extracellular matrix protein -3.15622
LEF1 lymphoid enhancer-binding factor 1 -3.15622
TMEM88 transmembrane protein 88 -3.15622
RUNX3 runt-related transcription factor 3 -3.15622
C1QTNF2 C1q and tumor necrosis factor related protein 2 -3.15622
ADRA1D adrenoceptor alpha 1D -3.15622
S100B S100 calcium binding protein B -3.15622
RHOXF2 Rhox homeobox family, member 2 -3.15622
SCRG1 stimulator of chondrogenesis 1 -3.15622
PPARG peroxisome proliferator-activated receptor gamma -3.15622
MUC1 mucin 1, cell surface associated -3.15622
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -3.15622
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime -3.15622
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -3.15622
ANGPT4 angiopoietin 4 -3.15622
ZDHHC17 zinc finger, DHHC-type containing 17 -3.15622
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -3.15622
TMEM229A transmembrane protein 229A -3.15622
TMC8 transmembrane channel-like 8 -3.15622
ARHGAP20 Rho GTPase activating protein 20 -3.15622
PRDM7 PR domain containing 7 -3.15622
BCO1 beta-carotene oxygenase 1 -3.15622
IL1A interleukin 1, alpha -3.15622
MTUS1 microtubule associated tumor suppressor 1 -3.15622
PCDHGA9 protocadherin gamma subfamily A, 9 -3.15622
EPHA10 EPH receptor A10 -3.15622
BGN biglycan -3.15622
TMEM150B transmembrane protein 150B -3.15622
LSMEM1 leucine-rich single-pass membrane protein 1 -3.15622
TP63 tumor protein p63 -3.15622
ALOXE3 arachidonate lipoxygenase 3 -3.15622
EFCAB12 EF-hand calcium binding domain 12 -3.15622
TMEM272 transmembrane protein 272 -3.15622
PLA2G2C phospholipase A2, group IIC -3.15622
EQTN equatorin, sperm acrosome associated -3.15622
TPRA1 transmembrane protein, adipocyte asscociated 1 -3.10274
TTC21A tetratricopeptide repeat domain 21A -3.07908
FSTL3 follistatin-like 3 (secreted glycoprotein) -3.07396
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -3.04668
C3ORF52 chromosome 3 open reading frame 52 -3.03789
EXOC6 exocyst complex component 6 -2.95214
GTF2IRD2B GTF2I repeat domain containing 2B -2.90918
SUMO3 small ubiquitin-like modifier 3 -2.90918
ZNF407 zinc finger protein 407 -2.8292
AXIN2 axin 2 -2.81493
HSPA2 heat shock 70kDa protein 2 -2.77893
TPM2 tropomyosin 2 (beta) -2.77706
TOMM70 translocase of outer mitochondrial membrane 70 -2.72411
STARD5 StAR-related lipid transfer (START) domain containing 5 -2.70848
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 -2.70671
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -2.62229
DISP1 dispatched homolog 1 (Drosophila) -2.56435
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -2.5036
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 -2.49759
CENPC centromere protein C -2.40379
KPNA7 karyopherin alpha 7 (importin alpha 8) -2.39369
ADORA1 adenosine A1 receptor -2.39369
ATF2 activating transcription factor 2 -2.38871
ABRAXAS1 abraxas 1, BRCA1 A complex subunit -2.37314
SDHAF2 succinate dehydrogenase complex assembly factor 2 -2.34292
ATOSB atos homolog B -2.34292
RPUSD4 RNA pseudouridylate synthase domain containing 4 -2.34292
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.31625
TSC22D3 TSC22 domain family, member 3 -2.29996
LMNA lamin A/C -2.28648
C1R complement component 1, r subcomponent -2.25786
FAM229A family with sequence similarity 229, member A -2.25786
CALCRL calcitonin receptor-like -2.25786
EPHX4 epoxide hydrolase 4 -2.25786
KCNK17 potassium channel, two pore domain subfamily K, member 17 -2.25386
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -2.24698
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -2.20872
RSL24D1 ribosomal L24 domain containing 1 -2.19586
FBXO48 F-box protein 48 -2.1767
CLCN7 chloride channel, voltage-sensitive 7 -2.1728
AP1M2 adaptor-related protein complex 1, mu 2 subunit -2.1574
PPP1R35 protein phosphatase 1, regulatory subunit 35 -2.14435
ADRA1A adrenoceptor alpha 1A -2.14435
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 -2.14435
CFAP44 cilia and flagella associated protein 44 -2.14435
H2BC17 H2B clustered histone 17 -2.14435
TMEM278 transmembrane protein 278 -2.14435
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 -2.14435
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 -2.14435
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -2.14435
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.14435
HIST1H2BI histone cluster 1, H2bi -2.14435
SLC35F1 solute carrier family 35, member F1 -2.14401
SYPL2 synaptophysin-like 2 -2.14401
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.12979
CREBZF CREB/ATF bZIP transcription factor -2.10683
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -2.08279
UCK2 uridine-cytidine kinase 2 -2.04999
HINT1 histidine triad nucleotide binding protein 1 -2.04131
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 -2.01671
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.0141
RADIL Ras association and DIL domains -2.00418
RIDA reactive intermediate imine deaminase A homolog -2.0039
CERCAM cerebral endothelial cell adhesion molecule -2.0039
SLC44A5 solute carrier family 44, member 5 -2.0039
KIF14 kinesin family member 14 -2.0039