SHROOM1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description shroom family member 1|SHROOM family members play diverse roles in the development of the nervous system and other tissues (Hagens et al., 2006 [PubMed 16615870]).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 134549)
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Genes

277 genes differentially expressed following the SHROOM1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GPR75 G protein-coupled receptor 75 3.45969
TRIM31 tripartite motif containing 31 3.45969
TNMD tenomodulin 3.45969
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 3.45969
LRRN4CL LRRN4 C-terminal like 3.45969
EPN3 epsin 3 3.45969
TMBIM1 transmembrane BAX inhibitor motif containing 1 3.45969
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9 3.45969
CD5L CD5 molecule-like 3.45969
OAZ3 ornithine decarboxylase antizyme 3 3.45969
NPPC natriuretic peptide C 3.45969
WFDC9 WAP four-disulfide core domain 9 3.45969
LY86 lymphocyte antigen 86 3.45969
COL9A2 collagen, type IX, alpha 2 3.45969
RAB7B RAB7B, member RAS oncogene family 3.45969
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 3.45969
RNASE6 ribonuclease, RNase A family, k6 3.45969
PODNL1 podocan-like 1 3.45969
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 3.45969
RHOJ ras homolog family member J 3.45969
KCNK2 potassium channel, two pore domain subfamily K, member 2 3.45969
SELPLG selectin P ligand 3.36348
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 3.36348
SLFN11 schlafen family member 11 3.36348
DUXB double homeobox B 3.36348
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 3.36348
ADGRE3 adhesion G protein-coupled receptor E3 3.36348
GPR52 G protein-coupled receptor 52 3.36348
SPAG8 sperm associated antigen 8 3.36348
AKR7L aldo-keto reductase family 7-like (gene/pseudogene) 3.36348
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 3.36348
UCN urocortin 3.36348
OR56A5 olfactory receptor, family 56, subfamily A, member 5 3.36348
FOXA1 forkhead box A1 3.36348
LRRC14B leucine rich repeat containing 14B 3.36348
DLL4 delta-like 4 (Drosophila) 3.36348
MISP mitotic spindle positioning 3.36348
GPR101 G protein-coupled receptor 101 3.36348
POSTN periostin, osteoblast specific factor 3.36348
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 3.36348
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 3.36348
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 3.36348
BMP5 bone morphogenetic protein 5 3.36348
OSR2 odd-skipped related transciption factor 2 3.36348
IL5RA interleukin 5 receptor, alpha 3.36348
GJB3 gap junction protein, beta 3, 31kDa 3.36348
CNTNAP4 contactin associated protein-like 4 3.36348
ZNF583 zinc finger protein 583 3.36348
COL19A1 collagen, type XIX, alpha 1 3.36348
RGS21 regulator of G-protein signaling 21 3.36348
PRG4 proteoglycan 4 3.36348
TRPA1 transient receptor potential cation channel, subfamily A, member 1 3.36348
GATA6 GATA binding protein 6 3.36348
ARL14EPL ADP-ribosylation factor-like 14 effector protein-like 3.36348
BDKRB1 bradykinin receptor B1 3.36348
PROX2 prospero homeobox 2 3.36348
SIM1 single-minded family bHLH transcription factor 1 3.36348
GPR35 G protein-coupled receptor 35 3.36348
CLDN14 claudin 14 3.36348
C2ORF72 chromosome 2 open reading frame 72 3.36348
VSIR V-set immunoregulatory receptor 3.36348
TBXT T-box transcription factor T 3.36348
MINAR2 membrane integral NOTCH2 associated receptor 2 3.36348
AJM1 apical junction component 1 homolog 3.36348
TERB2 telomere repeat binding bouquet formation protein 2 3.36348
GNG5B G protein subunit gamma 5B 3.36348
CCR8 chemokine (C-C motif) receptor 8 3.36348
CCR3 chemokine (C-C motif) receptor 3 3.36348
TAS2R3 taste receptor, type 2, member 3 3.36348
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 3.36348
FPR2 formyl peptide receptor 2 3.36348
LOC124909439 uncharacterized LOC124909439 3.36348
BPIFA2 BPI fold containing family A, member 2 3.36348
RAB44 RAB44, member RAS oncogene family 3.36348
TUBA3C tubulin, alpha 3c 3.36348
OR6C4 olfactory receptor, family 6, subfamily C, member 4 3.36348
AXDND1 axonemal dynein light chain domain containing 1 3.36348
ANXA13 annexin A13 3.36348
CATSPER3 cation channel, sperm associated 3 3.36348
DMBX1 diencephalon/mesencephalon homeobox 1 3.36348
PGC progastricsin (pepsinogen C) 3.36348
MIA melanoma inhibitory activity 3.36348
ZNF257 zinc finger protein 257 3.36348
LSP1 lymphocyte-specific protein 1 3.36348
EXOC3L4 exocyst complex component 3-like 4 3.36348
RAMACL RNA guanine-7 methyltransferase activating subunit like 3.36348
STAP1 signal transducing adaptor family member 1 3.36348
WFDC1 WAP four-disulfide core domain 1 3.36348
WNT7B wingless-type MMTV integration site family, member 7B 3.36348
BARHL2 BarH-like homeobox 2 3.36348
PRSS55 protease, serine, 55 3.36348
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 3.36348
KLK15 kallikrein-related peptidase 15 3.36348
C5AR2 complement component 5a receptor 2 3.36348
CARD6 caspase recruitment domain family, member 6 3.36348
EPO erythropoietin 3.36348
SLC7A4 solute carrier family 7, member 4 3.36348
EGR3 early growth response 3 3.36348
CLCA1 chloride channel accessory 1 3.36348
CCDC27 coiled-coil domain containing 27 3.36348
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 3.36348
GAL3ST2 galactose-3-O-sulfotransferase 2 3.36348
ADAM2 ADAM metallopeptidase domain 2 3.36348
BTNL9 butyrophilin-like 9 3.36348
SPANXC SPANX family, member C 3.36348
PIH1D2 PIH1 domain containing 2 3.36348
EDN3 endothelin 3 3.36348
HAMP hepcidin antimicrobial peptide 3.36348
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 3.36348
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 3.36348
SMR3B submaxillary gland androgen regulated protein 3B 3.36348
DMRTB1 DMRT-like family B with proline-rich C-terminal, 1 3.36348
CCDC152 coiled-coil domain containing 152 3.36348
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 3.36348
THEM5 thioesterase superfamily member 5 3.36348
OR10G3 olfactory receptor, family 10, subfamily G, member 3 3.36348
RASA4 RAS p21 protein activator 4 3.36348
ZNF132 zinc finger protein 132 3.36348
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 3.36348
CEACAM20 carcinoembryonic antigen-related cell adhesion molecule 20 3.36348
MROH2A maestro heat-like repeat family member 2A 3.36348
WFDC13 WAP four-disulfide core domain 13 3.36348
EVI2A ecotropic viral integration site 2A 3.36348
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 3.36348
HOXB3 homeobox B3 3.36348
OR52N5 olfactory receptor, family 52, subfamily N, member 5 3.36348
MSMB microseminoprotein, beta- 3.36348
RNASE9 ribonuclease, RNase A family, 9 (non-active) 3.36348
FAIM2 Fas apoptotic inhibitory molecule 2 3.36348
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 3.36348
PSG8 pregnancy specific beta-1-glycoprotein 8 3.36348
LRRC15 leucine rich repeat containing 15 3.36348
TRIM7 tripartite motif containing 7 3.36348
MUC7 mucin 7, secreted 3.36348
PNMA5 paraneoplastic Ma antigen family member 5 3.36348
ADAP1 ArfGAP with dual PH domains 1 3.36348
MMP12 matrix metallopeptidase 12 3.36348
RRH retinal pigment epithelium-derived rhodopsin homolog 3.35949
SPINT4 serine peptidase inhibitor, Kunitz type 4 3.35949
CASR calcium-sensing receptor 3.35949
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 3.19666
FAM162A family with sequence similarity 162, member A 2.9771
MT1M metallothionein 1M 2.87437
PROX1 prospero homeobox 1 2.87437
DOCK4 dedicator of cytokinesis 4 2.5136
PADI3 peptidyl arginine deiminase, type III 2.5072
GLRA2 glycine receptor, alpha 2 2.49018
MRPL55 mitochondrial ribosomal protein L55 2.46527
RNF24 ring finger protein 24 2.41804
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 2.37009
FETUB fetuin B 2.37009
PRSS22 protease, serine, 22 2.3497
TMIGD3 transmembrane and immunoglobulin domain containing 3 2.3497
DDA1 DET1 and DDB1 associated 1 2.32894
PLEKHO1 pleckstrin homology domain containing, family O member 1 2.32185
ARC activity-regulated cytoskeleton-associated protein 2.30533
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 2.3023
FAM9B family with sequence similarity 9, member B 2.30207
ZNF43 zinc finger protein 43 2.27346
WIPI2 WD repeat domain, phosphoinositide interacting 2 2.25586
ZNF821 zinc finger protein 821 2.24988
ZNF485 zinc finger protein 485 2.235
RNF141 ring finger protein 141 2.23144
RNFT1 ring finger protein, transmembrane 1 2.22898
DPCD deleted in primary ciliary dyskinesia homolog (mouse) 2.21614
KLHL13 kelch-like family member 13 2.17669
FCHO2 FCH domain only 2 2.17259
RPH3AL rabphilin 3A-like (without C2 domains) 2.16506
EGR1 early growth response 1 2.10796
ODAD2 outer dynein arm docking complex subunit 2 2.10707
PLSCR3 phospholipid scramblase 3 2.10052
PTRH2 peptidyl-tRNA hydrolase 2 2.07042
ISM1 isthmin 1, angiogenesis inhibitor 2.06634
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 2.06465
PTPN3 protein tyrosine phosphatase, non-receptor type 3 2.03794
SCRN3 secernin 3 2.0297
MAP3K5 mitogen-activated protein kinase kinase kinase 5 2.0245
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 2.02278
PER3 period circadian clock 3 2.02152
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 2.02152
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2.02124
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 2.02003
RSAD2 radical S-adenosyl methionine domain containing 2 2.02003
FPR3 formyl peptide receptor 3 2.02003

decreased expression

Symbol Name Standardized Value
EBF4 early B-cell factor 4 -3.45969
DCAF12L1 DDB1 and CUL4 associated factor 12-like 1 -3.45969
MMP26 matrix metallopeptidase 26 -3.45969
MST1 macrophage stimulating 1 -3.43194
DNAH10 dynein, axonemal, heavy chain 10 -3.43194
SLC46A1 solute carrier family 46 (folate transporter), member 1 -3.43194
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -3.43194
PHETA1 PH domain containing endocytic trafficking adaptor 1 -3.43046
KLC3 kinesin light chain 3 -3.36348
RRAS related RAS viral (r-ras) oncogene homolog -3.36348
BMX BMX non-receptor tyrosine kinase -3.35949
LDHC lactate dehydrogenase C -3.35949
IRF8 interferon regulatory factor 8 -3.35949
C11ORF16 chromosome 11 open reading frame 16 -3.35949
HHEX hematopoietically expressed homeobox -3.35949
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 -3.35949
SACK1A scaffolding CK1 anchoring protein A -3.35949
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 -3.35949
SP100 SP100 nuclear antigen -3.35949
LOC105378220 macrophage receptor MARCO-like -3.35949
FLI1 Fli-1 proto-oncogene, ETS transcription factor -3.35949
NWD2 NACHT and WD repeat domain containing 2 -3.35949
IRX3 iroquois homeobox 3 -3.35949
TUBB8 tubulin, beta 8 class VIII -3.35949
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 -3.35949
PADI1 peptidyl arginine deiminase, type I -3.35949
POM121L2 POM121 transmembrane nucleoporin-like 2 -3.35949
IL9R interleukin 9 receptor -3.35949
LSMEM1 leucine-rich single-pass membrane protein 1 -3.35949
LAMB3 laminin, beta 3 -3.35949
MPIG6B megakaryocyte and platelet inhibitory receptor G6b -3.35949
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans) -3.35949
CPNE8-AS1 CPNE8 antisense RNA 1 -3.35949
FBXO40 F-box protein 40 -3.35949
SLC45A4 solute carrier family 45, member 4 -3.35949
TMEM234 transmembrane protein 234 -3.35949
TACSTD2 tumor-associated calcium signal transducer 2 -3.35949
CIROZ ciliated left-right organizer protein containing ZP-N domains -3.35949
BHMT betaine--homocysteine S-methyltransferase -3.35949
C7ORF57 chromosome 7 open reading frame 57 -3.35949
PRDM6 PR domain containing 6 -3.35949
PROZ protein Z, vitamin K-dependent plasma glycoprotein -3.35949
SPRR2F small proline-rich protein 2F -3.35949
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 -3.21302
ANO6 anoctamin 6 -3.07311
ZNF518B zinc finger protein 518B -2.87437
NIN ninein (GSK3B interacting protein) -2.78571
EIF3M eukaryotic translation initiation factor 3, subunit M -2.78571
SEH1L SEH1-like (S. cerevisiae) -2.75527
TRIM41 tripartite motif containing 41 -2.71042
NEURL1 neuralized E3 ubiquitin protein ligase 1 -2.70838
NSMCE3 NSE3 homolog, SMC5-SMC6 complex component -2.5136
THBS2 thrombospondin 2 -2.47874
ANKEF1 ankyrin repeat and EF-hand domain containing 1 -2.47822
CCDC158 coiled-coil domain containing 158 -2.47141
FBXL16 F-box and leucine-rich repeat protein 16 -2.47141
ZNF516 zinc finger protein 516 -2.47141
ILDR2 immunoglobulin-like domain containing receptor 2 -2.47141
FGFR1OP2 FGFR1 oncogene partner 2 -2.425
NGRN neugrin, neurite outgrowth associated -2.41804
KCTD19 potassium channel tetramerization domain containing 19 -2.37009
WDR5B WD repeat domain 5B -2.37009
ZNF816 zinc finger protein 816 -2.3497
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -2.32894
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -2.30533
CHIC2 cysteine-rich hydrophobic domain 2 -2.29767
PDE9A phosphodiesterase 9A -2.29146
CD320 CD320 molecule -2.29146
CLCN5 chloride channel, voltage-sensitive 5 -2.25639
MGAM maltase-glucoamylase -2.25586
BRICD5 BRICHOS domain containing 5 -2.25586
GRTP1 growth hormone regulated TBC protein 1 -2.25339
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -2.23598
PIGBOS1 PIGB opposite strand 1 -2.22898
TRIB2 tribbles pseudokinase 2 -2.21753
CFAP90 cilia and flagella associated protein 90 -2.21614
GRK4 G protein-coupled receptor kinase 4 -2.19667
FHIP2A FHF complex subunit HOOK interacting protein 2A -2.19342
ZFP62 ZFP62 zinc finger protein -2.16349
RASL12 RAS-like, family 12 -2.14157
SKAP1 src kinase associated phosphoprotein 1 -2.1091
CREG1 cellular repressor of E1A-stimulated genes 1 -2.10077
DGCR6 DiGeorge syndrome critical region gene 6 -2.09251
TMEM130 transmembrane protein 130 -2.09251
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 -2.09251
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -2.07437
COX6B2 cytochrome c oxidase subunit VIb polypeptide 2 (testis) -2.07209
TMC1 transmembrane channel-like 1 -2.0507
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 -2.0399
BAG5 BCL2-associated athanogene 5 -2.0343
LIPI lipase, member I -2.02152
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) -2.02003
MAP7D2 MAP7 domain containing 2 -2.01806