| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | sucrase-isomaltase (alpha-glucosidase)|This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.[provided by RefSeq, Apr 2010] (NCBI Entrez Gene Database, 6476) |
| External Link | https://ncbi.nlm.nih.gov/gene/6476 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the SI gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHP1 | calcineurin-like EF-hand protein 1 | 0.0228639 |
| POSTN | periostin, osteoblast specific factor | 0.0124252 |
| CETN2 | centrin, EF-hand protein, 2 | 0.0119809 |
| SIRT3 | sirtuin 3 | 0.0117829 |
| RPA3 | replication protein A3, 14kDa | 0.0116061 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.0113606 |
| FABP1 | fatty acid binding protein 1, liver | 0.0106573 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.0104872 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0101149 |
| COL1A2 | collagen, type I, alpha 2 | 0.0100919 |
| CLCA1 | chloride channel accessory 1 | 0.00984962 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00973536 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00948053 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00941476 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00936556 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | 0.00919609 |
| ADD3 | adducin 3 (gamma) | 0.00918013 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00917923 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00917368 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00902278 |
| E2F2 | E2F transcription factor 2 | 0.00899864 |
| NTS | neurotensin | 0.00896351 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00887807 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00884511 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | 0.00874909 |
| WDR61 | WD repeat domain 61 | 0.00872896 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00864484 |
| CD9 | CD9 molecule | 0.00846608 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.00834506 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00833987 |
| COL3A1 | collagen, type III, alpha 1 | 0.00831961 |
| CA2 | carbonic anhydrase II | 0.00824441 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | 0.00824166 |
| TLCD3A | TLC domain containing 3A | 0.00822952 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00816443 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.00812953 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00811416 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.00795191 |
| KRT1 | keratin 1, type II | 0.00791084 |
| EAPP | E2F-associated phosphoprotein | 0.00788962 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00786601 |
| RAB4A | RAB4A, member RAS oncogene family | 0.00784918 |
| FCGBP | Fc fragment of IgG binding protein | 0.00782296 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00781327 |
| TMEM14B | transmembrane protein 14B | 0.00779918 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00774688 |
| CDC42 | cell division cycle 42 | 0.00771221 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00771019 |
| KIF20A | kinesin family member 20A | 0.00767699 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | 0.00763999 |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.00763909 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00763759 |
| CD52 | CD52 molecule | 0.00761813 |
| SI | sucrase-isomaltase (alpha-glucosidase) | 0.00759454 |
| PRDX3 | peroxiredoxin 3 | 0.00755282 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00752188 |
| CRLF1 | cytokine receptor-like factor 1 | 0.00751409 |
| HIST3H2A | histone cluster 3, H2a | 0.0075009 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.00748237 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00745569 |
| CYTL1 | cytokine-like 1 | 0.0074114 |
| DHDDS | dehydrodolichyl diphosphate synthase | 0.00738168 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00736703 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00735876 |
| SPA17 | sperm autoantigenic protein 17 | 0.0073563 |
| ARG2 | arginase 2 | 0.00735364 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.00729732 |
| PSPH | phosphoserine phosphatase | 0.00726431 |
| PBK | PDZ binding kinase | 0.00723463 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | 0.0072091 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00718629 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 | 0.00715083 |
| DCK | deoxycytidine kinase | 0.00714726 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00712458 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00711124 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00704493 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.00703479 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00703262 |
| ADK | adenosine kinase | 0.00698775 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.00697632 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00695635 |
| CLEC10A | C-type lectin domain family 10, member A | 0.00691645 |
| MPO | myeloperoxidase | 0.00690727 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.0068822 |
| OAT | ornithine aminotransferase | 0.00687142 |
| CCNB2 | cyclin B2 | 0.0068696 |
| CALML3 | calmodulin-like 3 | 0.00683614 |
| TMEM38B | transmembrane protein 38B | 0.00678964 |
| TSPAN6 | tetraspanin 6 | 0.00678147 |
| FAM234B | family with sequence similarity 234 member B | 0.0067766 |
| TUBA1A | tubulin, alpha 1a | 0.0067656 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00676336 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00673181 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00672946 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00668647 |
| CNN3 | calponin 3, acidic | 0.00668617 |
| AFP | alpha-fetoprotein | 0.00668257 |
| NIPSNAP2 | nipsnap homolog 2 | 0.00667666 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0066044 |
| FCRL2 | Fc receptor-like 2 | 0.00657245 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00654831 |
| NVL | nuclear VCP-like | 0.00654528 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00654524 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00650753 |
| CRYL1 | crystallin, lambda 1 | 0.00648647 |
| TMEM231 | transmembrane protein 231 | 0.00648363 |
| MELK | maternal embryonic leucine zipper kinase | 0.00647807 |
| TYRP1 | tyrosinase-related protein 1 | 0.00646925 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00645446 |
| CCDC176 | coiled-coil domain containing 176 | 0.00645112 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | 0.00644389 |
| CHPT1 | choline phosphotransferase 1 | 0.00643444 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00641932 |
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.00640728 |
| LRRC19 | leucine rich repeat containing 19 | 0.00637227 |
| CA12 | carbonic anhydrase XII | 0.00636615 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0063144 |
| CD48 | CD48 molecule | 0.0062987 |
| CCNA2 | cyclin A2 | 0.00629566 |
| ZG16 | zymogen granule protein 16 | 0.00629553 |
| COMMD8 | COMM domain containing 8 | 0.00629289 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.00627435 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.00625334 |
| OCRL | oculocerebrorenal syndrome of Lowe | 0.00624367 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00623841 |
| PRPF4 | pre-mRNA processing factor 4 | 0.0062358 |
| ELOVL6 | ELOVL fatty acid elongase 6 | 0.00623446 |
| CCNE2 | cyclin E2 | 0.00622389 |
| FOXG1 | forkhead box G1 | 0.00621562 |
| CHKB | choline kinase beta | 0.00620888 |
| PRKD3 | protein kinase D3 | 0.00620263 |
| PBLD | phenazine biosynthesis-like protein domain containing | 0.00618875 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0061731 |
| IFT52 | intraflagellar transport 52 | 0.00616198 |
| MOCS2 | molybdenum cofactor synthesis 2 | 0.00615476 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 | 0.00615362 |
| MEP1A | meprin A, alpha (PABA peptide hydrolase) | 0.00614242 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 | 0.00613581 |
| CHIT1 | chitinase 1 (chitotriosidase) | 0.00613301 |
| CALML4 | calmodulin-like 4 | 0.0060585 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00605485 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00604502 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.00604158 |
| TMEM106C | transmembrane protein 106C | 0.0060283 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00602435 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.00602357 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00602147 |
| ARL3 | ADP-ribosylation factor-like 3 | 0.00601474 |
| INSIG1 | insulin induced gene 1 | 0.00600345 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 0.00598419 |
| NMT2 | N-myristoyltransferase 2 | 0.00598279 |
| HBD | hemoglobin, delta | 0.0059798 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.00596657 |
| QRSL1 | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 | 0.00596095 |
| FMO5 | flavin containing monooxygenase 5 | 0.00595917 |
| LRP2 | low density lipoprotein receptor-related protein 2 | 0.00595457 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.00593516 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00593401 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00593081 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 | 0.00592217 |
| LOR | loricrin | 0.00591638 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.00588897 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00588208 |
| ACE2 | angiotensin I converting enzyme 2 | 0.0058782 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic | 0.00587241 |
| PRKCA | protein kinase C, alpha | 0.00587152 |
| FOXC1 | forkhead box C1 | 0.00586218 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00586117 |
| MAT2B | methionine adenosyltransferase II, beta | 0.0058587 |
| VIL1 | villin 1 | 0.00585182 |
| RNF138 | ring finger protein 138, E3 ubiquitin protein ligase | 0.00583912 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0058255 |
| IL27RA | interleukin 27 receptor, alpha | 0.00582243 |
| ZNF277 | zinc finger protein 277 | 0.00581848 |
| GSAP | gamma-secretase activating protein | 0.0058154 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00581537 |
| NSMCE4A | non-SMC element 4 homolog A (S. cerevisiae) | 0.00580811 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | 0.00580239 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.0058022 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00579103 |
| HIC2 | hypermethylated in cancer 2 | 0.00578713 |
| E2F5 | E2F transcription factor 5, p130-binding | 0.00578466 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.00577538 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00577435 |
| FAM162A | family with sequence similarity 162, member A | 0.00576372 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00575799 |
| OIP5 | Opa interacting protein 5 | 0.00575703 |
| CYBRD1 | cytochrome b reductase 1 | 0.00575624 |
| STOML2 | stomatin (EPB72)-like 2 | 0.00575103 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.00574479 |
| TMEM50B | transmembrane protein 50B | 0.0057345 |
| PRUNE1 | prune exopolyphosphatase 1 | 0.00572896 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00572697 |
| DSG1 | desmoglein 1 | 0.00572486 |
| CAVIN2 | caveolae associated protein 2 | 0.00572183 |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 | 0.00572111 |
| TMEM14A | transmembrane protein 14A | 0.00571781 |
| PDZK1 | PDZ domain containing 1 | 0.00570406 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 0.00569468 |
| ERCC8 | excision repair cross-complementation group 8 | 0.00568455 |
| FLT3LG | fms-related tyrosine kinase 3 ligand | 0.00568168 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00565915 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase | 0.00565663 |
| KYAT3 | kynurenine aminotransferase 3 | 0.00565346 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.0056529 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00563571 |
| KIF1B | kinesin family member 1B | 0.00562153 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | 0.00561675 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0056042 |
| GRB7 | growth factor receptor-bound protein 7 | 0.0056 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00559812 |
| DCTN3 | dynactin 3 (p22) | 0.00558004 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | 0.00555928 |
| RANBP1 | RAN binding protein 1 | 0.00555724 |
| PCYOX1 | prenylcysteine oxidase 1 | 0.00554855 |
| MMRN1 | multimerin 1 | 0.00553707 |
| ASF1A | anti-silencing function 1A histone chaperone | 0.00553004 |
| ADORA2B | adenosine A2b receptor | 0.00552 |
| RBBP8 | retinoblastoma binding protein 8 | 0.00551994 |
| CLCA4 | chloride channel accessory 4 | 0.00551216 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00550636 |
| SATB2 | SATB homeobox 2 | 0.00550413 |
| S100A10 | S100 calcium binding protein A10 | 0.00549742 |
| NRN1 | neuritin 1 | 0.0054928 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 0.0054849 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.00548119 |
| LIAS | lipoic acid synthetase | 0.00548043 |
| YEATS4 | YEATS domain containing 4 | 0.00546343 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | 0.00545604 |
| SMIM8 | small integral membrane protein 8 | 0.00545144 |
| ANXA4 | annexin A4 | 0.0054496 |
| DIPK1A | divergent protein kinase domain 1A | 0.0054378 |
| GAL | galanin/GMAP prepropeptide | 0.00542829 |
| NEK2 | NIMA-related kinase 2 | 0.00542576 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.00542427 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00541401 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | 0.00541283 |
| COX15 | cytochrome c oxidase assembly homolog 15 (yeast) | 0.00540498 |
| FCMR | Fc fragment of IgM receptor | 0.00539858 |
| ZNF226 | zinc finger protein 226 | 0.00538439 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.00538024 |
| CLC | Charcot-Leyden crystal galectin | 0.00537672 |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) | 0.00536201 |
| GMNN | geminin, DNA replication inhibitor | 0.00534702 |
| METTL9 | methyltransferase like 9 | 0.00534698 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00533614 |
| ERLIN2 | ER lipid raft associated 2 | 0.00532905 |
| ATP5PB | ATP synthase peripheral stalk-membrane subunit b | 0.00532325 |
| C11ORF71 | chromosome 11 open reading frame 71 | 0.00531978 |
| C1QBP | complement component 1, q subcomponent binding protein | 0.00531816 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KYNU | kynureninase | -0.0160477 |
| MX1 | MX dynamin-like GTPase 1 | -0.0156339 |
| KRT7 | keratin 7, type II | -0.0148921 |
| G0S2 | G0/G1 switch 2 | -0.0148517 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0148176 |
| HSPA1A | heat shock 70kDa protein 1A | -0.014407 |
| ACKR3 | atypical chemokine receptor 3 | -0.0138258 |
| IFI44L | interferon-induced protein 44-like | -0.0134224 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0133651 |
| S100A8 | S100 calcium binding protein A8 | -0.0128234 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0127339 |
| NEFH | neurofilament, heavy polypeptide | -0.0121688 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0118848 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0116026 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0115892 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0111546 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.0109673 |
| KLK11 | kallikrein-related peptidase 11 | -0.0109466 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.0109264 |
| TNS3 | tensin 3 | -0.010731 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0106884 |
| IER5 | immediate early response 5 | -0.0106318 |
| CD163 | CD163 molecule | -0.0106139 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.0105763 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0105526 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -0.0105305 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0104102 |
| DST | dystonin | -0.0103294 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.0102082 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.0101451 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0101354 |
| MGLL | monoglyceride lipase | -0.0101133 |
| BST2 | bone marrow stromal cell antigen 2 | -0.0100694 |
| MLPH | melanophilin | -0.00988673 |
| CADM1 | cell adhesion molecule 1 | -0.00987825 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.00980438 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00974493 |
| ASS1 | argininosuccinate synthase 1 | -0.0097079 |
| RB1 | retinoblastoma 1 | -0.00968876 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00964472 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00955758 |
| MX2 | MX dynamin-like GTPase 2 | -0.00955066 |
| PDZD2 | PDZ domain containing 2 | -0.0094803 |
| MID1IP1 | MID1 interacting protein 1 | -0.00922574 |
| IFI44 | interferon-induced protein 44 | -0.0090421 |
| LAMB3 | laminin, beta 3 | -0.00900946 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00890923 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00889369 |
| IL6 | interleukin 6 | -0.00889116 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0088584 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00885545 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.00881733 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00878066 |
| INSR | insulin receptor | -0.0087779 |
| S100A9 | S100 calcium binding protein A9 | -0.00876888 |
| ECM1 | extracellular matrix protein 1 | -0.00872307 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00871734 |
| TPBG | trophoblast glycoprotein | -0.00867539 |
| CD93 | CD93 molecule | -0.0086589 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00864827 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00863286 |
| CHGB | chromogranin B | -0.00860142 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00860061 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00859069 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00857902 |
| XAF1 | XIAP associated factor 1 | -0.00856407 |
| PODXL | podocalyxin-like | -0.00854457 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00849902 |
| GOLGA8H | golgin A8 family, member H | -0.00847482 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00847164 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00844531 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | -0.00839492 |
| HMOX1 | heme oxygenase 1 | -0.00837174 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00829541 |
| NRCAM | neuronal cell adhesion molecule | -0.00828696 |
| MAGEA3 | melanoma antigen family A3 | -0.00827986 |
| EGR1 | early growth response 1 | -0.00823209 |
| KLK10 | kallikrein-related peptidase 10 | -0.00820479 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00816431 |
| PLXNB2 | plexin B2 | -0.00813182 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00807316 |
| CD14 | CD14 molecule | -0.00806624 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.00806212 |
| THBS4 | thrombospondin 4 | -0.00805067 |
| PSAP | prosaposin | -0.00800494 |
| SLC43A3 | solute carrier family 43, member 3 | -0.00794211 |
| C1QA | complement component 1, q subcomponent, A chain | -0.0079056 |
| CD53 | CD53 molecule | -0.00787367 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00787173 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00786641 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -0.00786542 |
| IRS2 | insulin receptor substrate 2 | -0.00784004 |
| APOD | apolipoprotein D | -0.00778947 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.007789 |
| GAS6 | growth arrest-specific 6 | -0.00774549 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.00774063 |
| KIF2C | kinesin family member 2C | -0.00772546 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00769538 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.00769182 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00765225 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00764924 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00763858 |
| IRS1 | insulin receptor substrate 1 | -0.00761597 |
| ANXA3 | annexin A3 | -0.00761176 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00759176 |
| IRF7 | interferon regulatory factor 7 | -0.00758933 |
| TSPAN13 | tetraspanin 13 | -0.00756277 |
| TMEM176B | transmembrane protein 176B | -0.00754907 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00753137 |
| L1CAM | L1 cell adhesion molecule | -0.00753048 |
| C1R | complement component 1, r subcomponent | -0.00747941 |
| RRBP1 | ribosome binding protein 1 | -0.00745416 |
| SCG5 | secretogranin V | -0.00744574 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.00736356 |
| ATF3 | activating transcription factor 3 | -0.00734304 |
| TGFA | transforming growth factor, alpha | -0.00730126 |
| PLXNC1 | plexin C1 | -0.00728713 |
| IL1RN | interleukin 1 receptor antagonist | -0.0072788 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.00727088 |
| CNTN1 | contactin 1 | -0.00726244 |
| CSF1R | colony stimulating factor 1 receptor | -0.00722194 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | -0.00721503 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00720905 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.0071629 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) | -0.00715264 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00712482 |
| LCN2 | lipocalin 2 | -0.00712328 |
| RUNX1 | runt-related transcription factor 1 | -0.00711054 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.00708844 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 | -0.00708829 |
| DUSP4 | dual specificity phosphatase 4 | -0.0070882 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.00708477 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00706864 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.00699583 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00699338 |
| RND3 | Rho family GTPase 3 | -0.00698965 |
| MCOLN1 | mucolipin 1 | -0.00697573 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | -0.00695973 |
| TUBA4A | tubulin, alpha 4a | -0.00694157 |
| HLA-B | major histocompatibility complex, class I, B | -0.00693937 |
| TGM2 | transglutaminase 2 | -0.00692594 |
| C3 | complement component 3 | -0.00691562 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00690954 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -0.00688803 |
| PCDH17 | protocadherin 17 | -0.00688105 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00687734 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00687404 |
| INHBA | inhibin, beta A | -0.00683859 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00683695 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00683561 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00682646 |
| GOLGA8A | golgin A8 family, member A | -0.00681873 |
| VWF | von Willebrand factor | -0.00681187 |
| CYB5R2 | cytochrome b5 reductase 2 | -0.00678183 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00677123 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00675196 |
| DOCK9 | dedicator of cytokinesis 9 | -0.00674573 |
| AGR2 | anterior gradient 2 | -0.00673978 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.00673604 |
| RRAGD | Ras-related GTP binding D | -0.00672928 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00670587 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00669955 |
| TASOR2 | transcription activation suppressor family member 2 | -0.006694 |
| CUX1 | cut-like homeobox 1 | -0.00668741 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.00668315 |
| LAMC2 | laminin, gamma 2 | -0.00668155 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00667687 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00666627 |
| CFB | complement factor B | -0.00663958 |
| MXRA5 | matrix-remodelling associated 5 | -0.00663308 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0066271 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00662308 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.0066117 |
| TSC22D2 | TSC22 domain family, member 2 | -0.00660521 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00660048 |
| MYRF | myelin regulatory factor | -0.00660039 |
| RGS16 | regulator of G-protein signaling 16 | -0.00659809 |
| ABHD4 | abhydrolase domain containing 4 | -0.00657021 |
| LAT2 | linker for activation of T cells family, member 2 | -0.00657006 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.00651536 |
| CD99 | CD99 molecule | -0.00651136 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00650885 |
| LONP1 | lon peptidase 1, mitochondrial | -0.00649877 |
| SSH3 | slingshot protein phosphatase 3 | -0.0064952 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00647376 |
| QKI | QKI, KH domain containing, RNA binding | -0.00645082 |
| MEG3 | maternally expressed 3 (non-protein coding) | -0.00644085 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.00642757 |
| CDCP1 | CUB domain containing protein 1 | -0.00639473 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | -0.00638946 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00636096 |
| SIRPA | signal-regulatory protein alpha | -0.00635167 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00632739 |
| VEGFA | vascular endothelial growth factor A | -0.00632659 |
| PRRC2C | proline-rich coiled-coil 2C | -0.00630951 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00630177 |
| COL7A1 | collagen, type VII, alpha 1 | -0.00630047 |
| IL1B | interleukin 1, beta | -0.00629435 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | -0.00629028 |
| HEATR1 | HEAT repeat containing 1 | -0.00628044 |
| INA | internexin neuronal intermediate filament protein, alpha | -0.00626438 |
| S100P | S100 calcium binding protein P | -0.00626219 |
| STIP1 | stress-induced phosphoprotein 1 | -0.00625589 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00624485 |
| LIF | leukemia inhibitory factor | -0.00623771 |
| APOL1 | apolipoprotein L, 1 | -0.00621872 |
| OPTN | optineurin | -0.00618481 |
| SYT1 | synaptotagmin I | -0.00616085 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.00615908 |
| FKBP2 | FK506 binding protein 2, 13kDa | -0.00615579 |
| PLCB4 | phospholipase C, beta 4 | -0.00614301 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00613998 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00612564 |
| CEL | carboxyl ester lipase | -0.0061182 |
| KRT17 | keratin 17, type I | -0.00611668 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00608511 |
| CCN3 | cellular communication network factor 3 | -0.0060783 |
| FHL2 | four and a half LIM domains 2 | -0.00607619 |
| RTN2 | reticulon 2 | -0.00605812 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00604881 |
| ITGB4 | integrin, beta 4 | -0.00604827 |
| JMJD6 | jumonji domain containing 6 | -0.00604664 |
| MFAP5 | microfibrillar associated protein 5 | -0.0060307 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00602624 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00601294 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00600291 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00600189 |
| PLIN2 | perilipin 2 | -0.00598867 |
| ZNF281 | zinc finger protein 281 | -0.00598687 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | -0.00598378 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00597125 |
| YIPF3 | Yip1 domain family, member 3 | -0.00597057 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00596334 |
| ADAR | adenosine deaminase, RNA-specific | -0.00594756 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00594119 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00593477 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | -0.00592528 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00592073 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00591594 |
| LAMB1 | laminin, beta 1 | -0.00590537 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.00590154 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00589919 |
| NKX3-1 | NK3 homeobox 1 | -0.00589736 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | -0.00589171 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.00588776 |
| SDC1 | syndecan 1 | -0.00588088 |
| FGF1 | fibroblast growth factor 1 (acidic) | -0.00587231 |
| STXBP2 | syntaxin binding protein 2 | -0.0058712 |
