| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | siah E3 ubiquitin protein ligase 1|This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6477) |
| External Link | https://ncbi.nlm.nih.gov/gene/6477 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the SIAH1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0121195 |
| ASRGL1 | asparaginase like 1 | 0.0100868 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0093033 |
| LMNB1 | lamin B1 | 0.00915819 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00894079 |
| CP | ceruloplasmin (ferroxidase) | 0.00782487 |
| EREG | epiregulin | 0.00775914 |
| C2CD5 | C2 calcium-dependent domain containing 5 | 0.00741958 |
| HMGA1 | high mobility group AT-hook 1 | 0.00737107 |
| CDCA4 | cell division cycle associated 4 | 0.00694983 |
| PCNA | proliferating cell nuclear antigen | 0.00694194 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00690195 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00682933 |
| FASN | fatty acid synthase | 0.00680911 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00667441 |
| MEIS2 | Meis homeobox 2 | 0.00658798 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00658547 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00655506 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00648686 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00638935 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00637779 |
| GAS1 | growth arrest-specific 1 | 0.00637041 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00636943 |
| SYT1 | synaptotagmin I | 0.00636045 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00629552 |
| PLK1 | polo-like kinase 1 | 0.0060972 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00602678 |
| COG7 | component of oligomeric golgi complex 7 | 0.00600437 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.00598096 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00597637 |
| PRPF19 | pre-mRNA processing factor 19 | 0.00591447 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00589783 |
| SFPQ | splicing factor proline/glutamine-rich | 0.00586099 |
| MMP1 | matrix metallopeptidase 1 | 0.00584534 |
| CCNA2 | cyclin A2 | 0.00584123 |
| RTN3 | reticulon 3 | 0.00580587 |
| FBLN5 | fibulin 5 | 0.00580063 |
| NEFH | neurofilament, heavy polypeptide | 0.00577907 |
| KIF20A | kinesin family member 20A | 0.00577821 |
| ACTN1 | actinin, alpha 1 | 0.00577785 |
| MFAP2 | microfibrillar-associated protein 2 | 0.0057473 |
| OLFM1 | olfactomedin 1 | 0.00566994 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 0.00564964 |
| LTF | lactotransferrin | 0.00561075 |
| FOXM1 | forkhead box M1 | 0.00558911 |
| CCNB2 | cyclin B2 | 0.00554626 |
| ANXA6 | annexin A6 | 0.00550868 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.00550592 |
| DACH1 | dachshund family transcription factor 1 | 0.00550453 |
| FBXO21 | F-box protein 21 | 0.00548054 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00546734 |
| CCNF | cyclin F | 0.00545422 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00541165 |
| LCN2 | lipocalin 2 | 0.0053685 |
| IRS2 | insulin receptor substrate 2 | 0.00534594 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00531533 |
| MMP10 | matrix metallopeptidase 10 | 0.00528718 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00526522 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00523016 |
| PHB2 | prohibitin 2 | 0.00519219 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00516878 |
| PLAT | plasminogen activator, tissue | 0.0051552 |
| GATA2 | GATA binding protein 2 | 0.00514601 |
| SAC3D1 | SAC3 domain containing 1 | 0.00513769 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00510033 |
| GANAB | glucosidase, alpha; neutral AB | 0.00507649 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00505428 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00504225 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.00501646 |
| ERLIN1 | ER lipid raft associated 1 | 0.00499171 |
| SEPHS1 | selenophosphate synthetase 1 | 0.00498307 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00493941 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00493319 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.00491804 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00491355 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.00487575 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | 0.00487216 |
| MSMB | microseminoprotein, beta- | 0.00485265 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0048494 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00479659 |
| TRIM28 | tripartite motif containing 28 | 0.00479572 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00479392 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | 0.00475583 |
| RFK | riboflavin kinase | 0.00468672 |
| KIF1B | kinesin family member 1B | 0.00466898 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.00464323 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.00460886 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00460851 |
| TEAD4 | TEA domain family member 4 | 0.00460562 |
| MEIS1 | Meis homeobox 1 | 0.00458461 |
| NPY | neuropeptide Y | 0.00455986 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.00454902 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00453201 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00452574 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00452539 |
| RNF130 | ring finger protein 130 | 0.00452336 |
| IL6ST | interleukin 6 signal transducer | 0.00451408 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.00449746 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | 0.004486 |
| HLTF | helicase-like transcription factor | 0.00448395 |
| TDO2 | tryptophan 2,3-dioxygenase | 0.00447769 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00447515 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00446965 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00445755 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00444178 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0044409 |
| PRMT1 | protein arginine methyltransferase 1 | 0.00443092 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.00442632 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.00441806 |
| PODXL | podocalyxin-like | 0.00441622 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 0.00440031 |
| RGCC | regulator of cell cycle | 0.00439449 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00439049 |
| TPBG | trophoblast glycoprotein | 0.0043821 |
| NUP85 | nucleoporin 85kDa | 0.00437415 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00436163 |
| ARG1 | arginase 1 | 0.0043377 |
| HYOU1 | hypoxia up-regulated 1 | 0.0043315 |
| IPO7 | importin 7 | 0.00432454 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0043069 |
| ANOS1 | anosmin 1 | 0.00428463 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.00428243 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00426326 |
| CDCA3 | cell division cycle associated 3 | 0.00425215 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00422621 |
| SELL | selectin L | 0.00421515 |
| GCH1 | GTP cyclohydrolase 1 | 0.00421285 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00419778 |
| TRAPPC3 | trafficking protein particle complex 3 | 0.00418885 |
| CDC42 | cell division cycle 42 | 0.00418643 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00418168 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00417817 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.00416261 |
| FABP1 | fatty acid binding protein 1, liver | 0.00416189 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.00416047 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | 0.00415809 |
| VPS51 | vacuolar protein sorting 51 homolog (S. cerevisiae) | 0.00415401 |
| NRIP3 | nuclear receptor interacting protein 3 | 0.0041509 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00415007 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00413946 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.00413941 |
| AMD1 | adenosylmethionine decarboxylase 1 | 0.00413614 |
| LEPR | leptin receptor | 0.00413151 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.00412474 |
| DMXL2 | Dmx-like 2 | 0.00411148 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00411095 |
| MRPL12 | mitochondrial ribosomal protein L12 | 0.00409957 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00409694 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00408246 |
| THBS1 | thrombospondin 1 | 0.00408107 |
| BAX | BCL2-associated X protein | 0.00407459 |
| NANOG | Nanog homeobox | 0.00406618 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00406095 |
| CTSG | cathepsin G | 0.00405474 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | 0.00405255 |
| PEG3 | paternally expressed 3 | 0.00404485 |
| TFR2 | transferrin receptor 2 | 0.00402245 |
| MRPL58 | mitochondrial ribosomal protein L58 | 0.00402234 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00401877 |
| STK10 | serine/threonine kinase 10 | 0.00400244 |
| MMP7 | matrix metallopeptidase 7 | 0.00399383 |
| IPO5 | importin 5 | 0.00399252 |
| GUCY2C | guanylate cyclase 2C | 0.00398624 |
| NOL9 | nucleolar protein 9 | 0.00398465 |
| ZNF318 | zinc finger protein 318 | 0.0039836 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00396807 |
| CD14 | CD14 molecule | 0.00395786 |
| GCHFR | GTP cyclohydrolase I feedback regulator | 0.00395475 |
| AEBP1 | AE binding protein 1 | 0.00394765 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00393776 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 | 0.00393607 |
| RPIA | ribose 5-phosphate isomerase A | 0.00392723 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.00391511 |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) | 0.00391407 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | 0.00390156 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.00389081 |
| MMP12 | matrix metallopeptidase 12 | 0.00389047 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.00388235 |
| AHCY | adenosylhomocysteinase | 0.0038781 |
| AURKB | aurora kinase B | 0.00387296 |
| WDR82 | WD repeat domain 82 | 0.00386907 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 0.00386682 |
| RSBN1 | round spermatid basic protein 1 | 0.00386559 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.00385308 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00384715 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00383894 |
| CD93 | CD93 molecule | 0.00382495 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00382267 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00381996 |
| ZNF384 | zinc finger protein 384 | 0.0038154 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | 0.00381333 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 0.00380365 |
| AOX1 | aldehyde oxidase 1 | 0.00379608 |
| MAPT | microtubule-associated protein tau | 0.00377762 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00377233 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.00376888 |
| GAL | galanin/GMAP prepropeptide | 0.0037687 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | 0.00376031 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.0037591 |
| PRPF8 | pre-mRNA processing factor 8 | 0.00375614 |
| EPHB4 | EPH receptor B4 | 0.00375602 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.00375508 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00375094 |
| TMPO | thymopoietin | 0.00374442 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00373838 |
| RNF138 | ring finger protein 138, E3 ubiquitin protein ligase | 0.00373477 |
| ESR1 | estrogen receptor 1 | 0.00372941 |
| RYBP | RING1 and YY1 binding protein | 0.00372662 |
| INSIG1 | insulin induced gene 1 | 0.00370858 |
| RBBP4 | retinoblastoma binding protein 4 | 0.00370785 |
| KLK6 | kallikrein-related peptidase 6 | 0.00370717 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 0.00370536 |
| PEX5 | peroxisomal biogenesis factor 5 | 0.00370211 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0036987 |
| GRK2 | G protein-coupled receptor kinase 2 | 0.00369819 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.00368762 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.00368482 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.00367147 |
| ACP2 | acid phosphatase 2, lysosomal | 0.00367077 |
| APOC1 | apolipoprotein C-I | 0.00366815 |
| COL5A1 | collagen, type V, alpha 1 | 0.00366784 |
| OIP5 | Opa interacting protein 5 | 0.00366483 |
| CLC | Charcot-Leyden crystal galectin | 0.00365738 |
| WDR7 | WD repeat domain 7 | 0.00365731 |
| DENND2D | DENN/MADD domain containing 2D | 0.00365205 |
| VANGL1 | VANGL planar cell polarity protein 1 | 0.00364927 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00364672 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00364476 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.00363448 |
| THY1 | Thy-1 cell surface antigen | 0.00362486 |
| HOXB2 | homeobox B2 | 0.0036223 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00362176 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.00361774 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F | 0.00361583 |
| SET | SET nuclear proto-oncogene | 0.0036133 |
| MRPS2 | mitochondrial ribosomal protein S2 | 0.00361097 |
| MEX3D | mex-3 RNA binding family member D | 0.00361044 |
| SRM | spermidine synthase | 0.00360606 |
| COBL | cordon-bleu WH2 repeat protein | 0.00360457 |
| C5ORF30 | chromosome 5 open reading frame 30 | 0.00360134 |
| MDRV | muscular dystrophy, with rimmed vacuoles | 0.00359956 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.00359785 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00359116 |
| NOP2 | NOP2 nucleolar protein | 0.00359018 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00358811 |
| MALL | mal, T-cell differentiation protein-like | 0.00358155 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 0.00358102 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00356834 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00356768 |
| TPX2 | TPX2, microtubule-associated | 0.00356634 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CRYAB | crystallin, alpha B | -0.0104429 |
| HOPX | HOP homeobox | -0.00910267 |
| ATF3 | activating transcription factor 3 | -0.008689 |
| S100A10 | S100 calcium binding protein A10 | -0.00796289 |
| BLNK | B-cell linker | -0.00756792 |
| ADM | adrenomedullin | -0.00714739 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00692723 |
| PKP1 | plakophilin 1 | -0.00685925 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00676942 |
| XIC | X chromosome inactivation center | -0.00672446 |
| SYNM | synemin, intermediate filament protein | -0.00639024 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00638587 |
| ANXA4 | annexin A4 | -0.00629374 |
| FZD6 | frizzled class receptor 6 | -0.00627311 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00619096 |
| TP63 | tumor protein p63 | -0.00615631 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00608384 |
| S100A8 | S100 calcium binding protein A8 | -0.00607611 |
| DSG3 | desmoglein 3 | -0.00606844 |
| PERP | PERP, TP53 apoptosis effector | -0.00603361 |
| SPRR2B | small proline-rich protein 2B | -0.00600408 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.005999 |
| MELK | maternal embryonic leucine zipper kinase | -0.00598308 |
| MT1X | metallothionein 1X | -0.00594107 |
| DSTN | destrin (actin depolymerizing factor) | -0.00593936 |
| IDS | iduronate 2-sulfatase | -0.00593139 |
| MXRA7 | matrix-remodelling associated 7 | -0.00590232 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00587065 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00580179 |
| DSP | desmoplakin | -0.00576143 |
| KRT14 | keratin 14, type I | -0.00575696 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00567123 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00566943 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -0.0056399 |
| ARG2 | arginase 2 | -0.00563844 |
| NDRG1 | N-myc downstream regulated 1 | -0.00555724 |
| KRT16 | keratin 16, type I | -0.00552581 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -0.00552028 |
| RGS13 | regulator of G-protein signaling 13 | -0.00549605 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00549054 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00547926 |
| IL1R2 | interleukin 1 receptor, type II | -0.00547638 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00547398 |
| EMP1 | epithelial membrane protein 1 | -0.00544881 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00543705 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00542201 |
| LBH | limb bud and heart development | -0.00536796 |
| PRDX2 | peroxiredoxin 2 | -0.00536282 |
| STC2 | stanniocalcin 2 | -0.00535295 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00532728 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.00529781 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | -0.0052911 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00527231 |
| SDC4 | syndecan 4 | -0.00526872 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00525988 |
| CALML3 | calmodulin-like 3 | -0.00525001 |
| STC1 | stanniocalcin 1 | -0.00520838 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00519326 |
| POSTN | periostin, osteoblast specific factor | -0.00518986 |
| ORMDL2 | ORMDL sphingolipid biosynthesis regulator 2 | -0.0051683 |
| PALLD | palladin, cytoskeletal associated protein | -0.00514903 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.00510424 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00510418 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00509699 |
| ABLIM1 | actin binding LIM protein 1 | -0.00508041 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00505322 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.0050483 |
| TMPRSS11E | transmembrane protease, serine 11E | -0.00502837 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00500898 |
| IRF9 | interferon regulatory factor 9 | -0.00499502 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.00498275 |
| SLC16A6 | solute carrier family 16, member 6 | -0.00497443 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.0049727 |
| SPRR1B | small proline-rich protein 1B | -0.00496667 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00496131 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | -0.00494831 |
| OPHN1 | oligophrenin 1 | -0.00493685 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00491694 |
| CTSH | cathepsin H | -0.00489336 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00488896 |
| YIPF6 | Yip1 domain family, member 6 | -0.00488619 |
| TPST2 | tyrosylprotein sulfotransferase 2 | -0.00486918 |
| MAGEA3 | melanoma antigen family A3 | -0.00485442 |
| PLS3 | plastin 3 | -0.00484874 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.00484354 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00482582 |
| KRT6B | keratin 6B, type II | -0.0048217 |
| KRT6A | keratin 6A, type II | -0.00481598 |
| PMM2 | phosphomannomutase 2 | -0.00481101 |
| WDR45 | WD repeat domain 45 | -0.00478336 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.00476725 |
| RRAGD | Ras-related GTP binding D | -0.00474684 |
| KRT81 | keratin 81, type II | -0.00474489 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | -0.00472296 |
| ENAH | enabled homolog (Drosophila) | -0.00471666 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | -0.0047126 |
| GLA | galactosidase, alpha | -0.00470708 |
| KRT13 | keratin 13, type I | -0.00470131 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00469997 |
| RAB29 | RAB29, member RAS oncogene family | -0.00468746 |
| GSPT2 | G1 to S phase transition 2 | -0.00468527 |
| HSPB11 | heat shock protein family B (small), member 11 | -0.00468433 |
| GATA6 | GATA binding protein 6 | -0.00468001 |
| MAGEA11 | melanoma antigen family A11 | -0.004672 |
| STK38L | serine/threonine kinase 38 like | -0.00467135 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0046524 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.00465052 |
| TRIM29 | tripartite motif containing 29 | -0.00462358 |
| KRT5 | keratin 5, type II | -0.00460999 |
| PXDC1 | PX domain containing 1 | -0.00460782 |
| S100A11 | S100 calcium binding protein A11 | -0.00459794 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.00458358 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -0.00456824 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -0.00455483 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) | -0.00454388 |
| ALAS2 | 5'-aminolevulinate synthase 2 | -0.00452626 |
| REEP5 | receptor accessory protein 5 | -0.00452385 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00448578 |
| SPRR3 | small proline-rich protein 3 | -0.00448542 |
| CCNB1 | cyclin B1 | -0.00447545 |
| TRIB3 | tribbles pseudokinase 3 | -0.00446565 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | -0.00446433 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.0044534 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00444267 |
| MT1H | metallothionein 1H | -0.00443081 |
| PGF | placental growth factor | -0.00441875 |
| PRF1 | perforin 1 (pore forming protein) | -0.00440699 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00438868 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00437886 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00436792 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00436669 |
| IL1RN | interleukin 1 receptor antagonist | -0.00436465 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00435829 |
| TSPO | translocator protein (18kDa) | -0.00435477 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0043473 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00434257 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -0.00433621 |
| KRT15 | keratin 15, type I | -0.00432222 |
| FILIP1L | filamin A interacting protein 1-like | -0.00430092 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0042823 |
| YIPF1 | Yip1 domain family, member 1 | -0.00428207 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | -0.00427893 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | -0.00427388 |
| MAGEA1 | melanoma antigen family A1 | -0.00426713 |
| THBD | thrombomodulin | -0.00426335 |
| FSD1 | fibronectin type III and SPRY domain containing 1 | -0.00425419 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00425354 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00420035 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0041954 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00419537 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00417239 |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 | -0.00417081 |
| ADRB2 | adrenoceptor beta 2, surface | -0.00416955 |
| BCAP31 | B-cell receptor-associated protein 31 | -0.0041694 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00416763 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.0041646 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.00413974 |
| COL5A2 | collagen, type V, alpha 2 | -0.00413764 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00413634 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00413529 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00412788 |
| PFKP | phosphofructokinase, platelet | -0.00412508 |
| IL17RB | interleukin 17 receptor B | -0.00412011 |
| GOLGB1 | golgin B1 | -0.00411811 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00409812 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.00409515 |
| PPL | periplakin | -0.00409413 |
| PELO | pelota homolog (Drosophila) | -0.00408377 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.00407734 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00407257 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.00407049 |
| TOB1 | transducer of ERBB2, 1 | -0.00406855 |
| GNLY | granulysin | -0.00406435 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.00406044 |
| MIR22HG | MIR22 host gene | -0.00406028 |
| CD9 | CD9 molecule | -0.00405846 |
| RCAN1 | regulator of calcineurin 1 | -0.00404669 |
| EGR2 | early growth response 2 | -0.00404414 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.00403098 |
| SNX13 | sorting nexin 13 | -0.00402792 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.00401538 |
| ADIRF | adipogenesis regulatory factor | -0.0040094 |
| RAB9A | RAB9A, member RAS oncogene family | -0.00400913 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.00400383 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00399285 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | -0.00397768 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0039746 |
| MEAK7 | MTOR associated protein, eak-7 homolog | -0.00395221 |
| TGIF1 | TGFB-induced factor homeobox 1 | -0.00394594 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.00394437 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.00393483 |
| CORO1C | coronin, actin binding protein, 1C | -0.0039285 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00391266 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00389913 |
| SPRR1A | small proline-rich protein 1A | -0.00388766 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.0038854 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00388359 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00387368 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00387048 |
| MOSPD1 | motile sperm domain containing 1 | -0.0038656 |
| MRPL33 | mitochondrial ribosomal protein L33 | -0.00385992 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.0038534 |
| DAD1 | defender against cell death 1 | -0.00383284 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.00382394 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00382119 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00381782 |
| SLC35G2 | solute carrier family 35, member G2 | -0.00381163 |
| CYRIA | CYFIP related Rac1 interactor A | -0.00378336 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.00377836 |
| FRY | furry homolog (Drosophila) | -0.00377769 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00376368 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00375728 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00375682 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.00375141 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.00374179 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.00373833 |
| OFD1 | oral-facial-digital syndrome 1 | -0.00372544 |
| SOCS2 | suppressor of cytokine signaling 2 | -0.00372526 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -0.00371486 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00370419 |
| GPC3 | glypican 3 | -0.00368776 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | -0.00367749 |
| CES1 | carboxylesterase 1 | -0.00367265 |
| ZNF45 | zinc finger protein 45 | -0.00367071 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00367067 |
| VEGFA | vascular endothelial growth factor A | -0.003664 |
| FGB | fibrinogen beta chain | -0.00366247 |
| IRS1 | insulin receptor substrate 1 | -0.00365934 |
| USB1 | U6 snRNA biogenesis 1 | -0.00365927 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00365709 |
| CERS4 | ceramide synthase 4 | -0.0036566 |
| MAGEA12 | melanoma antigen family A12 | -0.00363735 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00363301 |
| CTBS | chitobiase, di-N-acetyl- | -0.0036327 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00362898 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -0.00362738 |
| LYRM1 | LYR motif containing 1 | -0.00361363 |
| PWP1 | PWP1 homolog (S. cerevisiae) | -0.00361222 |
| MPG | N-methylpurine-DNA glycosylase | -0.003607 |
| FMOD | fibromodulin | -0.00360609 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00360006 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00359583 |
| MAGED1 | melanoma antigen family D1 | -0.00359335 |
| ADA | adenosine deaminase | -0.00358534 |
| CDIP1 | cell death-inducing p53 target 1 | -0.00358412 |
| MT1E | metallothionein 1E | -0.00358193 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00358145 |
| HCCS | holocytochrome c synthase | -0.00357737 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) | -0.00357275 |
