SIAH2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description siah E3 ubiquitin protein ligase 2|This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6478)
External Link http://www.ncbi.nlm.nih.gov/gene/6478
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Genes

59 interacting proteins for SIAH2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AFF1 AF4/FMR2 family, member 1
AKAP1 A kinase (PRKA) anchor protein 1
AR androgen receptor
ATN1 atrophin 1
CACYBP calcyclin binding protein
CCBE1 collagen and calcium binding EGF domains 1
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
DCC DCC netrin 1 receptor
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EGLN1 egl-9 family hypoxia-inducible factor 1
EGLN2 egl-9 family hypoxia-inducible factor 2
EGLN3 egl-9 family hypoxia-inducible factor 3
HDAC3 histone deacetylase 3
HIPK2 homeodomain interacting protein kinase 2
HIPK3 homeodomain interacting protein kinase 3
KAT2B K(lysine) acetyltransferase 2B
KAT5 K(lysine) acetyltransferase 5
MYD88 myeloid differentiation primary response 88
NFE2L2 nuclear factor, erythroid 2-like 2
NRF1 nuclear respiratory factor 1
OPRK1 opioid receptor, kappa 1
OPRM1 opioid receptor, mu 1
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PIAS1 protein inhibitor of activated STAT, 1
PIAS2 protein inhibitor of activated STAT, 2
PIAS3 protein inhibitor of activated STAT, 3
PLCE1 phospholipase C, epsilon 1
PML promyelocytic leukemia
POU2AF1 POU class 2 associating factor 1
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
RBBP8 retinoblastoma binding protein 8
SETD2 SET domain containing 2
SH3RF1 SH3 domain containing ring finger 1
SKI SKI proto-oncogene
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCAIP synuclein, alpha interacting protein
SPRY2 sprouty homolog 2 (Drosophila)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SYP synaptophysin
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TNK2 tyrosine kinase, non-receptor, 2
TP53BP2 tumor protein p53 binding protein 2
TPX2 TPX2, microtubule-associated
TRAF2 TNF receptor-associated factor 2
UBC ubiquitin C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2I ubiquitin-conjugating enzyme E2I
UBE2L6 ubiquitin-conjugating enzyme E2L 6
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP19 ubiquitin specific peptidase 19
VAV1 vav 1 guanine nucleotide exchange factor