SIG-M5 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Acute Myeloid Leukemia Tumour (Cell Model Passports, SIDM00396)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00396
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Genes

197 proteins associated with the cell line SIG-M5 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ACSF3 acyl-CoA synthetase family member 3
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ALDH16A1 aldehyde dehydrogenase 16 family, member A1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ARL8B ADP-ribosylation factor-like 8B
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATG7 autophagy related 7
C20ORF27 chromosome 20 open reading frame 27
CAAP1 caspase activity and apoptosis inhibitor 1
CAB39 calcium binding protein 39
CAB39L calcium binding protein 39-like
CDC23 cell division cycle 23
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CSF3 colony stimulating factor 3 (granulocyte)
CSTA cystatin A (stefin A)
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DSP desmoplakin
EIF4A1 eukaryotic translation initiation factor 4A1
ETV6 ets variant 6
FGF2 fibroblast growth factor 2 (basic)
GRN granulin
HAUS1 HAUS augmin-like complex, subunit 1
HEATR1 HEAT repeat containing 1
HMGN3-AS1 HMGN3 antisense RNA 1
INSR insulin receptor
IRF2BP2 interferon regulatory factor 2 binding protein 2
KNTC1 kinetochore associated 1
LGALS9 lectin, galactoside-binding, soluble, 9
LMO7 LIM domain 7
LOC100129924 uncharacterized LOC100129924
LOC102723922 uncharacterized LOC102723922
LOC105372503 uncharacterized LOC105372503
LYZ lysozyme
MAN2B1 mannosidase, alpha, class 2B, member 1
MAP7D3 MAP7 domain containing 3
MAPK14 mitogen-activated protein kinase 14
MEF2D myocyte enhancer factor 2D
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MICALL2 MICAL-like 2
MNDA myeloid cell nuclear differentiation antigen
MOB2 MOB kinase activator 2
MTMR14 myotubularin related protein 14
MYLK myosin light chain kinase
MYO5C myosin VC
NDC80 NDC80 kinetochore complex component
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase
PLS1 plastin 1
PNP purine nucleoside phosphorylase
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPF8 pre-mRNA processing factor 8
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PUS1 pseudouridylate synthase 1
PWWP2A PWWP domain containing 2A
PYCARD PYD and CARD domain containing
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RECQL RecQ helicase-like
RETN resistin
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF32 ring finger protein 32
RPL26 ribosomal protein L26
RPL3 ribosomal protein L3
RPL7 ribosomal protein L7
RPS16 ribosomal protein S16
RPS9 ribosomal protein S9
RTTN rotatin
S100A8 S100 calcium binding protein A8
SBNO1 strawberry notch homolog 1 (Drosophila)
SCFD2 sec1 family domain containing 2
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SETD3 SET domain containing 3
SHPK sedoheptulokinase
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SYNE2 spectrin repeat containing, nuclear envelope 2
TJAP1 tight junction associated protein 1 (peripheral)
TRIM22 tripartite motif containing 22
TYMP thymidine phosphorylase
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
VAMP8 vesicle-associated membrane protein 8
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae)
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae)
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADD1 adducin 1 (alpha)
AK4 adenylate kinase 4
AK9 adenylate kinase 9
AKAP1 A kinase (PRKA) anchor protein 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ANPEP alanyl (membrane) aminopeptidase
ATAD5 ATPase family, AAA domain containing 5
BCAP29 B-cell receptor-associated protein 29
BRCA1 breast cancer 1, early onset
C15ORF62 chromosome 15 open reading frame 62
CALU calumenin
CAST calpastatin
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCDC134 coiled-coil domain containing 134
CELF1 CUGBP, Elav-like family member 1
CMC2 C-x(9)-C motif containing 2
COPD2 Chronic obstructive pulmonary disease QTL 2
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56
DEGS1 delta(4)-desaturase, sphingolipid 1
DHRS1 dehydrogenase/reductase (SDR family) member 1
DIAPH3 diaphanous-related formin 3
DSTN destrin (actin depolymerizing factor)
EMC10 ER membrane protein complex subunit 10
EMC4 ER membrane protein complex subunit 4
GOLIM4 golgi integral membrane protein 4
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HSP90AB2P heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene
HSPA4L heat shock 70kDa protein 4-like
ILF3 interleukin enhancer binding factor 3, 90kDa
KIF13B kinesin family member 13B
LIN7C lin-7 homolog C (C. elegans)
MACF1 microtubule-actin crosslinking factor 1
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MARVELD2 MARVEL domain containing 2
MEF2B myocyte enhancer factor 2B
MRPL30 mitochondrial ribosomal protein L30
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NFXL1 nuclear transcription factor, X-box binding-like 1
NPTN neuroplastin
NR2C2 nuclear receptor subfamily 2, group C, member 2
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16
PARVB parvin, beta
PGRMC1 progesterone receptor membrane component 1
PGRMC2 progesterone receptor membrane component 2
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRKCB protein kinase C, beta
PROCR protein C receptor, endothelial
RAB18 RAB18, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RACGAP1 Rac GTPase activating protein 1
RAD21 RAD21 homolog (S. pombe)
RBM4 RNA binding motif protein 4
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RDH13 retinol dehydrogenase 13 (all-trans/9-cis)
RDX radixin
RHOF ras homolog family member F (in filopodia)
RMDN3 regulator of microtubule dynamics 3
RPL36AP9 ribosomal protein L36a pseudogene 9
RPLP1 ribosomal protein, large, P1
S100A10 S100 calcium binding protein A10
SCAMP4 secretory carrier membrane protein 4
SCFD1 sec1 family domain containing 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SMC1A structural maintenance of chromosomes 1A
SMC3 structural maintenance of chromosomes 3
SMIM20 small integral membrane protein 20
SOX6 SRY (sex determining region Y)-box 6
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SRR serine racemase
SRSF10 serine/arginine-rich splicing factor 10
STEAP3 STEAP family member 3, metalloreductase
STRN4 striatin, calmodulin binding protein 4
STX5 syntaxin 5
SYF2 SYF2 pre-mRNA-splicing factor
TADA2B transcriptional adaptor 2B
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TMC5 transmembrane channel-like 5
TMED1 transmembrane emp24 protein transport domain containing 1
TPMT thiopurine S-methyltransferase
TRAPPC12 trafficking protein particle complex 12
TSPYL1 TSPY-like 1
TTC19 tetratricopeptide repeat domain 19
UNC93B1 unc-93 homolog B1 (C. elegans)
USP47 ubiquitin specific peptidase 47
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VDAC2 voltage-dependent anion channel 2
ZFPL1 zinc finger protein-like 1