SIK1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description salt-inducible kinase 1| (NCBI Entrez Gene Database, 150094)
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Genes

340 genes differentially expressed following the SIK1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CCDC17 coiled-coil domain containing 17 2.67083
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.67083
CARD18 caspase recruitment domain family, member 18 2.67083
MAP3K7CL MAP3K7 C-terminal like 2.67083
FAM167A family with sequence similarity 167, member A 2.67083
SACK1A scaffolding CK1 anchoring protein A 2.67083
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 2.67083
GLUD2 glutamate dehydrogenase 2 2.67083
MILR1 mast cell immunoglobulin-like receptor 1 2.67083
OSR2 odd-skipped related transciption factor 2 2.67083
GSTM1 glutathione S-transferase mu 1 2.67083
NOTO notochord homeobox 2.67083
RASL10A RAS-like, family 10, member A 2.67083
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 2.67083
GGT5 gamma-glutamyltransferase 5 2.67083
NKX2-4 NK2 homeobox 4 2.67083
PCDHA7 protocadherin alpha 7 2.67083
RAB44 RAB44, member RAS oncogene family 2.67083
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 2.67083
MCEMP1 mast cell-expressed membrane protein 1 2.67083
HNF4A hepatocyte nuclear factor 4, alpha 2.67083
NDRG1 N-myc downstream regulated 1 2.67083
SIX6 SIX homeobox 6 2.67083
TMPRSS11A transmembrane protease, serine 11A 2.67083
CES5A carboxylesterase 5A 2.67083
TMEM100 transmembrane protein 100 2.67083
OC90 otoconin 90 2.67083
NPIPA8 nuclear pore complex interacting protein family, member A8 2.67083
SLC44A4 solute carrier family 44, member 4 2.67083
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 2.67083
IL2RB interleukin 2 receptor, beta 2.67083
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 2.67083
THSD1 thrombospondin, type I, domain containing 1 2.67083
OIT3 oncoprotein induced transcript 3 2.67083
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 2.67083
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 2.67083
STMN4 stathmin-like 4 2.67083
MEIKIN meiotic kinetochore factor 2.67083
TTLL2 tubulin tyrosine ligase-like family member 2 2.67083
PAX2 paired box 2 2.67083
OLIG3 oligodendrocyte transcription factor 3 2.67083
REN renin 2.67083
C12ORF75 chromosome 12 open reading frame 75 2.67083
BIRC3 baculoviral IAP repeat containing 3 2.67083
UBE2S ubiquitin-conjugating enzyme E2S 2.67083
RAPSN receptor-associated protein of the synapse 2.67083
ZNF556 zinc finger protein 556 2.67083
TDRD9 tudor domain containing 9 2.67083
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 2.67083
FGF8 fibroblast growth factor 8 (androgen-induced) 2.67083
LOC124905976 uncharacterized LOC124905976 2.67083
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2.67083
SELE selectin E 2.67083
TMOD4 tropomodulin 4 (muscle) 2.67083
PCDHGA9 protocadherin gamma subfamily A, 9 2.67083
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.67083
CAPN9 calpain 9 2.67083
WDR83OS WD repeat domain 83 opposite strand 2.67083
PNLIPRP1 pancreatic lipase-related protein 1 2.67083
VN1R2 vomeronasal 1 receptor 2 2.67083
RD3 retinal degeneration 3 2.67083
DARS1 aspartyl-tRNA synthetase 1 2.67083
H3-5 H3.5 histone 2.67083
TTLL13 tubulin tyrosine ligase like 13 2.67083
FAM90A24 family with sequence similarity 90 member A24 2.67083
CIMIP1 ciliary microtubule inner protein 1 2.67083
TEX53 testis expressed 53 2.67083
THSD8 thrombospondin type 1 domain containing 8 2.67083
RAMACL RNA guanine-7 methyltransferase activating subunit like 2.67083
MAJIN membrane anchored junction protein 2.67083
CLXN calaxin 2.67083
SMIM41 small integral membrane protein 41 2.67083
CRPPA CDP-L-ribitol pyrophosphorylase A 2.67083
SELENOK selenoprotein K 2.67083
IQCF3 IQ motif containing F3 2.67083
PAPOLB poly(A) polymerase beta (testis specific) 2.67083
PRRT4 proline-rich transmembrane protein 4 2.67083
SH3TC2 SH3 domain and tetratricopeptide repeats 2 2.67083
MYH13 myosin, heavy chain 13, skeletal muscle 2.67083
TLR9 toll-like receptor 9 2.67083
TLR4 toll-like receptor 4 2.67083
NHLRC4 NHL repeat containing 4 2.67083
IL6 interleukin 6 2.67083
MSX1 msh homeobox 1 2.67083
MEOX1 mesenchyme homeobox 1 2.67083
NXPE4 neurexophilin and PC-esterase domain family, member 4 2.67083
CFAP45 cilia and flagella associated protein 45 2.67083
KCNT1 potassium channel, sodium activated subfamily T, member 1 2.67083
NPFF neuropeptide FF-amide peptide precursor 2.67083
SAG S-antigen; retina and pineal gland (arrestin) 2.67083
BDKRB1 bradykinin receptor B1 2.67083
RAB36 RAB36, member RAS oncogene family 2.67083
TSPAN8 tetraspanin 8 2.67083
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 2.67083
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 2.67083
GPR85 G protein-coupled receptor 85 2.67083
GSC goosecoid homeobox 2.67083
CDSN corneodesmosin 2.67083
TMEM179 transmembrane protein 179 2.67083
CLDN9 claudin 9 2.67083
APOH apolipoprotein H (beta-2-glycoprotein I) 2.67083
OR56A4 olfactory receptor, family 56, subfamily A, member 4 2.67083
LCNL1 lipocalin-like 1 2.67083
ZNF541 zinc finger protein 541 2.67083
EBLN1 endogenous Bornavirus-like nucleoprotein 1 2.67083
DQX1 DEAQ box RNA-dependent ATPase 1 2.67083
GRK1 G protein-coupled receptor kinase 1 2.67083
CXCR2 chemokine (C-X-C motif) receptor 2 2.67083
KRT222 keratin 222, type II 2.67083
HPN hepsin 2.67083
AKNAD1 AKNA domain containing 1 2.67083
ZNF703 zinc finger protein 703 2.67083
ZNF132 zinc finger protein 132 2.67083
CCL27 chemokine (C-C motif) ligand 27 2.67083
RNF224 ring finger protein 224 2.67083
GH2 growth hormone 2 2.67083
AMER3 APC membrane recruitment protein 3 2.67083
EPX eosinophil peroxidase 2.67083
CARD9 caspase recruitment domain family, member 9 2.67083
CIDEA cell death-inducing DFFA-like effector a 2.67083
SMYD1 SET and MYND domain containing 1 2.67083
ERMN ermin, ERM-like protein 2.67083
NT5C1A 5'-nucleotidase, cytosolic IA 2.67083
VAX2 ventral anterior homeobox 2 2.67083
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 2.67083
CAGE1 cancer antigen 1 2.67083
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 2.67083
GPR61 G protein-coupled receptor 61 2.67083
TRIM7 tripartite motif containing 7 2.67083
HMGB4 high mobility group box 4 2.67083
MEPE matrix extracellular phosphoglycoprotein 2.67083
CNGB1 cyclic nucleotide gated channel beta 1 2.67083
SFTA2 surfactant associated 2 2.67083
TMEM168 transmembrane protein 168 2.67083
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 2.67083
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.67083
CFH complement factor H 2.67083
VWF von Willebrand factor 2.67083
ARL6 ADP-ribosylation factor-like 6 2.67083
CFAP61 cilia and flagella associated protein 61 2.67083
DRD3 dopamine receptor D3 2.67083
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 2.67083
ALOXE3 arachidonate lipoxygenase 3 2.67083
CCL17 chemokine (C-C motif) ligand 17 2.67083
CCL15 chemokine (C-C motif) ligand 15 2.67083
ISLR immunoglobulin superfamily containing leucine-rich repeat 2.67083
CER1 cerberus 1, DAN family BMP antagonist 2.67083
PDZRN4 PDZ domain containing ring finger 4 2.67083
IGF2 insulin-like growth factor 2 2.67083
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.67083
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 2.67083
C5ORF46 chromosome 5 open reading frame 46 2.67083
GRAPL GRB2-related adaptor protein-like 2.67083
TMPRSS15 transmembrane protease, serine 15 2.67083
SYTL3 synaptotagmin-like 3 2.67083
CLCNKA chloride channel, voltage-sensitive Ka 2.67083
IL37 interleukin 37 2.67083
PCDHGA11 protocadherin gamma subfamily A, 11 2.67083
TMEM52B transmembrane protein 52B 2.67083
NRGN neurogranin (protein kinase C substrate, RC3) 2.67083
TMEM156 transmembrane protein 156 2.67083
ANGPTL6 angiopoietin-like 6 2.67083
ANXA9 annexin A9 2.67083
TEX38 testis expressed 38 2.67083
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 2.67083
TPRX1 tetra-peptide repeat homeobox 1 2.67083
POPDC2 popeye domain containing 2 2.67083
RBP4 retinol binding protein 4, plasma 2.67083
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.67083
TSKS testis-specific serine kinase substrate 2.67083
ITPKA inositol-trisphosphate 3-kinase A 2.67083
STOML3 stomatin (EPB72)-like 3 2.67083
RABGAP1L RAB GTPase activating protein 1-like 2.64644
RNFT2 ring finger protein, transmembrane 2 2.62318
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 2.61591
HK3 hexokinase 3 (white cell) 2.61363
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 2.60609
KATNAL2 katanin p60 subunit A-like 2 2.59361
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 2.58812
C11ORF58 chromosome 11 open reading frame 58 2.56986
PRODH proline dehydrogenase (oxidase) 1 2.55836
C2ORF42 chromosome 2 open reading frame 42 2.55316
C19ORF33 chromosome 19 open reading frame 33 2.49385
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 2.4905
STYXL2 serine/threonine/tyrosine interacting like 2 2.47841
SCARB1 scavenger receptor class B, member 1 2.45373
CDC14B cell division cycle 14B 2.43199
CTSO cathepsin O 2.41024
CSRNP3 cysteine-serine-rich nuclear protein 3 2.41024
NPTX1 neuronal pentraxin I 2.40351
CLU clusterin 2.40351
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 2.38894
KMT2D lysine (K)-specific methyltransferase 2D 2.38894
FBXL19 F-box and leucine-rich repeat protein 19 2.36536
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 2.34178
C11ORF86 chromosome 11 open reading frame 86 2.34178
DCLK3 doublecortin-like kinase 3 2.34178
ZFAND4 zinc finger, AN1-type domain 4 2.33681
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 2.33065
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 2.33065
TGFBR1 transforming growth factor, beta receptor 1 2.32993
FTCD formimidoyltransferase cyclodeaminase 2.3181
ZDHHC8 zinc finger, DHHC-type containing 8 2.31036
NELL1 NEL-like 1 (chicken) 2.27749
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 2.26388
CD86 CD86 molecule 2.26388
XTBD1 XRN2 binding domain containing 1 2.21671
PGBD2 piggyBac transposable element derived 2 2.21437
SPRED1 sprouty-related, EVH1 domain containing 1 2.21437
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 2.19434
AKAP7 A kinase (PRKA) anchor protein 7 2.19434
ANKRD45 ankyrin repeat domain 45 2.18989
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 2.14538
PLPP3 phospholipid phosphatase 3 2.13615
LAMP1 lysosomal-associated membrane protein 1 2.1299
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.12404
NOP9 NOP9 nucleolar protein 2.12364
TMEM143 transmembrane protein 143 2.11496
YTHDC1 YTH domain containing 1 2.11254
SMG8 SMG8 nonsense mediated mRNA decay factor 2.10166
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 2.09305
NUP160 nucleoporin 160kDa 2.0916
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 2.08513
RNF41 ring finger protein 41, E3 ubiquitin protein ligase 2.08513
ARSB arylsulfatase B 2.08277
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 2.08
VSIG10 V-set and immunoglobulin domain containing 10 2.07726
DOCK9 dedicator of cytokinesis 9 2.07129
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 2.05191
ANKUB1 ankyrin repeat and ubiquitin domain containing 1 2.05176
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1 2.05152
KREMEN2 kringle containing transmembrane protein 2 2.05152
PTPN9 protein tyrosine phosphatase, non-receptor type 9 2.02542
LBR lamin B receptor 2.02397
C9ORF40 chromosome 9 open reading frame 40 2.02397
SKIC2 SKI2 subunit of superkiller complex 2.02184
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 2.02184

decreased expression

Symbol Name Standardized Value
FGD5 FYVE, RhoGEF and PH domain containing 5 -2.67083
MUC20 mucin 20, cell surface associated -2.67083
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 -2.67083
TBX22 T-box 22 -2.67083
SPDYE6 speedy/RINGO cell cycle regulator family member E6 -2.67083
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 -2.67083
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 -2.67083
ATAD3C ATPase family, AAA domain containing 3C -2.67083
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 -2.67083
RNF25 ring finger protein 25 -2.67083
CDNF cerebral dopamine neurotrophic factor -2.67083
LRRC73 leucine rich repeat containing 73 -2.67083
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.67083
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 -2.67083
PELP1 proline, glutamate and leucine rich protein 1 -2.67083
MEP1B meprin A, beta -2.67083
SLC46A2 solute carrier family 46, member 2 -2.67083
LRRTM2 leucine rich repeat transmembrane neuronal 2 -2.67083
HEATR9 HEAT repeat containing 9 -2.67083
BTN1A1 butyrophilin, subfamily 1, member A1 -2.67083
NCMAP noncompact myelin associated protein -2.67083
EQTN equatorin, sperm acrosome associated -2.67083
NAPSA napsin A aspartic peptidase -2.67083
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 -2.67083
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 -2.67083
ADAMTSL2 ADAMTS-like 2 -2.67083
GUCY2D guanylate cyclase 2D, membrane (retina-specific) -2.67083
RGPD4 RANBP2-like and GRIP domain containing 4 -2.67083
LYRM1 LYR motif containing 1 -2.67083
CD8B CD8b molecule -2.67083
MAGEB17 melanoma antigen family B17 -2.67083
APP amyloid beta (A4) precursor protein -2.67083
LINGO1 leucine rich repeat and Ig domain containing 1 -2.67083
IFI35 interferon-induced protein 35 -2.67083
GRK7 G protein-coupled receptor kinase 7 -2.67083
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) -2.67083
TEDC1 tubulin epsilon and delta complex 1 -2.67083
TP53I13 tumor protein p53 inducible protein 13 -2.67083
ARG1 arginase 1 -2.67083
PRIM2 primase, DNA, polypeptide 2 (58kDa) -2.67083
CFAP157 cilia and flagella associated protein 157 -2.67083
C17ORF99 chromosome 17 open reading frame 99 -2.67083
PCDHA13 protocadherin alpha 13 -2.67083
ERFE erythroferrone -2.67083
DEFB131B defensin beta 131B -2.67083
DNAH10 dynein, axonemal, heavy chain 10 -2.67083
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) -2.67083
CISH cytokine inducible SH2-containing protein -2.67083
TSNAXIP1 translin-associated factor X interacting protein 1 -2.67083
CCER2 coiled-coil glutamate-rich protein 2 -2.67083
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -2.67083
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -2.65104
MMP26 matrix metallopeptidase 26 -2.61363
NKD2 naked cuticle homolog 2 (Drosophila) -2.61363
AMZ1 archaelysin family metallopeptidase 1 -2.61363
WDR25 WD repeat domain 25 -2.59779
BRD1 bromodomain containing 1 -2.59779
LAMP2 lysosomal-associated membrane protein 2 -2.59334
H4C12 H4 clustered histone 12 -2.58812
LRRC36 leucine rich repeat containing 36 -2.58812
GINM1 glycoprotein integral membrane 1 -2.54025
TRAIP TRAF interacting protein -2.47504
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 -2.45708
STBD1 starch binding domain 1 -2.40351
FSTL3 follistatin-like 3 (secreted glycoprotein) -2.3961
NPIPB7 nuclear pore complex interacting protein family, member B7 -2.3961
CREG1 cellular repressor of E1A-stimulated genes 1 -2.39537
TEPSIN TEPSIN adaptor related protein complex 4 accessory protein -2.33327
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) -2.32993
CORO7 coronin 7 -2.3181
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -2.3181
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -2.31739
ENSA endosulfine alpha -2.28563
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.25637
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit -2.24893
CCDC196 coiled-coil domain containing 196 -2.24729
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria -2.22261
GABPA GA binding protein transcription factor, alpha subunit 60kDa -2.21096
NUCB1 nucleobindin 1 -2.20966
PIWIL4 piwi-like RNA-mediated gene silencing 4 -2.17536
THAP9 THAP domain containing 9 -2.16629
UXS1 UDP-glucuronate decarboxylase 1 -2.14711
PTPN11 protein tyrosine phosphatase, non-receptor type 11 -2.147
SMKR1 small lysine-rich protein 1 -2.14539
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 -2.13615
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37 -2.12404
MEX3B mex-3 RNA binding family member B -2.11861
TMEM182 transmembrane protein 182 -2.11167
SOCS3 suppressor of cytokine signaling 3 -2.0916
TMEM167A transmembrane protein 167A -2.08072
MKNK2 MAP kinase interacting serine/threonine kinase 2 -2.06515
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 -2.06386
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae) -2.05191
CMC1 C-x(9)-C motif containing 1 -2.05191
H1-2 H1.2 linker histone, cluster member -2.05191
NANOG Nanog homeobox -2.05152
NEXMIF neurite extension and migration factor -2.04668
MRPS2 mitochondrial ribosomal protein S2 -2.02542
ANXA4 annexin A4 -2.02542
PIGT phosphatidylinositol glycan anchor biosynthesis, class T -2.02184
CFAP96 cilia and flagella associated protein 96 -2.01744
FAM110B family with sequence similarity 110, member B -2.01032
TAC4 tachykinin 4 (hemokinin) -2.00115