SIK2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description salt-inducible kinase 2| (NCBI Entrez Gene Database, 23235)
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Genes

343 genes differentially expressed following the SIK2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 3.04213
EBF2 early B-cell factor 2 3.04213
FOSB FBJ murine osteosarcoma viral oncogene homolog B 3.04213
SMIM5 small integral membrane protein 5 3.04213
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 3.04213
SERINC4 serine incorporator 4 3.04213
OR4D1 olfactory receptor, family 4, subfamily D, member 1 3.04213
ZMYND12 zinc finger, MYND-type containing 12 3.04213
KRT222 keratin 222, type II 3.04213
FMO1 flavin containing monooxygenase 1 3.04213
RFPL2 ret finger protein-like 2 3.04213
HUS1B HUS1 checkpoint homolog b (S. pombe) 3.04213
TSPAN16 tetraspanin 16 3.04213
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 3.04213
SLC35D3 solute carrier family 35, member D3 3.04213
FAM240A family with sequence similarity 240 member A 3.04213
STOML1 stomatin (EPB72)-like 1 3.04213
POMC proopiomelanocortin 3.04213
MUC22 mucin 22 3.04213
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative) 3.04213
GRK7 G protein-coupled receptor kinase 7 3.04213
CCN3 cellular communication network factor 3 3.04213
BTNL9 butyrophilin-like 9 3.04213
RAB9B RAB9B, member RAS oncogene family 3.02479
SIGLECL1 SIGLEC family like 1 3.02479
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 3.02479
ASB15 ankyrin repeat and SOCS box containing 15 3.02479
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 3.02479
SIX6 SIX homeobox 6 3.02479
NAPSA napsin A aspartic peptidase 3.02479
CDH5 cadherin 5, type 2 (vascular endothelium) 3.02479
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 3.02479
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 3.02479
ENTHD1 ENTH domain containing 1 3.02479
OR52A5 olfactory receptor, family 52, subfamily A, member 5 3.02479
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 3.02479
BSX brain-specific homeobox 3.02479
ARPP21 cAMP-regulated phosphoprotein, 21kDa 3.02479
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 3.02479
OCSTAMP osteoclast stimulatory transmembrane protein 3.02479
MAGED4 melanoma antigen family D4 3.02479
TCP11 t-complex 11, testis-specific 3.02479
RFX6 regulatory factor X, 6 3.02479
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) 3.02479
OXT oxytocin/neurophysin I prepropeptide 3.02479
TPSD1 tryptase delta 1 3.02479
SFTPB surfactant protein B 3.02479
HAS1 hyaluronan synthase 1 3.02479
CX3CL1 chemokine (C-X3-C motif) ligand 1 3.02479
PGAM4 phosphoglycerate mutase family member 4 3.02479
PGBDF plakoglobin binding and degradation factor 3.02479
CASP5 caspase 5, apoptosis-related cysteine peptidase 3.02479
SLC25A41 solute carrier family 25, member 41 3.02479
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 3.02479
DSG3 desmoglein 3 3.02479
ADGB androglobin 3.02479
CA7 carbonic anhydrase VII 3.02479
ETV2 ets variant 2 3.02479
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 3.02479
LOC124905976 uncharacterized LOC124905976 3.02479
OTOF otoferlin 3.02479
UNC93A unc-93 homolog A (C. elegans) 3.02479
VN1R1 vomeronasal 1 receptor 1 3.02479
DNAAF1 dynein, axonemal, assembly factor 1 3.02479
STX11 syntaxin 11 3.02479
C20ORF203 chromosome 20 open reading frame 203 3.02479
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 3.02479
TMEM190 transmembrane protein 190 3.02479
FCMR Fc fragment of IgM receptor 3.02479
HAO2 hydroxyacid oxidase 2 (long chain) 3.02479
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 3.02479
OR56B2 olfactory receptor family 56 subfamily B member 2 3.02479
CIMIP7 ciliary microtubule inner protein 7 3.02479
CPNE8-AS1 CPNE8 antisense RNA 1 3.02479
CIBAR2 CBY1 interacting BAR domain containing 2 3.02479
UBE2L5 ubiquitin conjugating enzyme E2 L5 3.02479
CFAP100 cilia and flagella associated protein 100 3.02479
LBHD2 LBH domain containing 2 3.02479
HTD2 hydroxyacyl-thioester dehydratase type 2 3.02479
NECTIN4 nectin cell adhesion molecule 4 3.02479
RASD1 RAS, dexamethasone-induced 1 3.02479
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 3.02479
OR7D2 olfactory receptor, family 7, subfamily D, member 2 3.02479
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 3.02479
SLAMF1 signaling lymphocytic activation molecule family member 1 3.02479
NPIPB9 nuclear pore complex interacting protein family, member B9 3.02479
ULBP1 UL16 binding protein 1 3.02479
CD79A CD79a molecule, immunoglobulin-associated alpha 3.02479
DSG1 desmoglein 1 3.02479
EDAR ectodysplasin A receptor 3.02479
VIT vitrin 3.02479
RHOXF2 Rhox homeobox family, member 2 3.02479
C1QTNF7 C1q and tumor necrosis factor related protein 7 3.02479
PRR4 proline rich 4 (lacrimal) 3.02479
CNTN6 contactin 6 3.02479
GDF6 growth differentiation factor 6 3.02479
GPR132 G protein-coupled receptor 132 3.02479
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 3.02479
ALG10B ALG10B, alpha-1,2-glucosyltransferase 3.02479
GINS3 GINS complex subunit 3 (Psf3 homolog) 3.02479
TACR2 tachykinin receptor 2 3.02479
EXOC3L4 exocyst complex component 3-like 4 3.02479
TMEM179 transmembrane protein 179 3.02479
OR2A5 olfactory receptor, family 2, subfamily A, member 5 3.02479
C2CD4B C2 calcium-dependent domain containing 4B 3.02479
MYF5 myogenic factor 5 3.02479
PALMD palmdelphin 3.02479
SPHKAP SPHK1 interactor, AKAP domain containing 3.02479
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 3.02479
LRCOL1 leucine rich colipase-like 1 3.02479
FSHR follicle stimulating hormone receptor 3.02479
APOH apolipoprotein H (beta-2-glycoprotein I) 3.02479
CEACAM16 carcinoembryonic antigen-related cell adhesion molecule 16 3.02479
TOPAZ1 testis and ovary specific PAZ domain containing 1 3.02479
KIF4B kinesin family member 4B 3.02479
TBC1D26 TBC1 domain family, member 26 3.02479
PRR15L proline rich 15-like 3.02479
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 3.02479
CHRM1 cholinergic receptor, muscarinic 1 3.02479
PATE3 prostate and testis expressed 3 3.02479
ARHGAP20 Rho GTPase activating protein 20 3.02479
CLIC2 chloride intracellular channel 2 3.02479
COX7B2 cytochrome c oxidase subunit VIIb2 3.02479
VWA3A von Willebrand factor A domain containing 3A 3.02479
OAZ3 ornithine decarboxylase antizyme 3 3.02479
WFDC6 WAP four-disulfide core domain 6 3.02479
IL19 interleukin 19 3.02479
SIM1 single-minded family bHLH transcription factor 1 3.02479
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3.02479
MAP3K19 mitogen-activated protein kinase kinase kinase 19 3.02479
EPHA10 EPH receptor A10 3.02479
AQP6 aquaporin 6, kidney specific 3.02479
FGR FGR proto-oncogene, Src family tyrosine kinase 3.02479
HCRT hypocretin (orexin) neuropeptide precursor 3.02479
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 3.02479
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 3.02479
SIGLEC15 sialic acid binding Ig-like lectin 15 3.02479
DAW1 dynein assembly factor with WDR repeat domains 1 3.02479
ANGPTL6 angiopoietin-like 6 3.02479
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 3.02479
FXYD3 FXYD domain containing ion transport regulator 3 3.02479
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 3.02479
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 3.02479
LPO lactoperoxidase 3.02479
LIF leukemia inhibitory factor 3.02479
NUPR1 nuclear protein, transcriptional regulator, 1 3.02479
TMEM52B transmembrane protein 52B 3.02479
R3HDML R3H domain containing-like 3.02479
PPP1R27 protein phosphatase 1, regulatory subunit 27 3.02479
NPY2R neuropeptide Y receptor Y2 3.02479
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 3.02479
ZNF648 zinc finger protein 648 3.02479
OR14A2 olfactory receptor, family 14, subfamily A, member 2 3.02479
ZNF497 zinc finger protein 497 3.02479
CD8B CD8b molecule 3.02479
DCST1 DC-STAMP domain containing 1 3.02479
RGS8 regulator of G-protein signaling 8 3.02479
PASD1 PAS domain containing 1 3.02479
IFNK interferon, kappa 3.02479
IFNE interferon, epsilon 3.02479
LGALS14 lectin, galactoside-binding, soluble, 14 3.02479
PRICKLE4 prickle homolog 4 (Drosophila) 3.02479
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) 3.02479
AARSD1 alanyl-tRNA synthetase domain containing 1 2.96383
ZNF703 zinc finger protein 703 2.96157
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 2.94455
GASK1A golgi associated kinase 1A 2.83841
RBM14 RNA binding motif protein 14 2.69419
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 2.63632
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 2.63632
EPB41L3 erythrocyte membrane protein band 4.1-like 3 2.60486
PBX2 pre-B-cell leukemia homeobox 2 2.603
RAD51B RAD51 paralog B 2.56178
ANKRD10 ankyrin repeat domain 10 2.55717
MED26 mediator complex subunit 26 2.55028
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 2.51791
NCOA6 nuclear receptor coactivator 6 2.47388
XPA xeroderma pigmentosum, complementation group A 2.47214
CIAO1 cytosolic iron-sulfur assembly component 1 2.43226
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 2.42959
MSL3 male-specific lethal 3 homolog (Drosophila) 2.42959
H3C6 H3 clustered histone 6 2.42774
RBM39 RNA binding motif protein 39 2.4139
BIN1 bridging integrator 1 2.41229
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 2.41229
OR56A3 olfactory receptor, family 56, subfamily A, member 3 2.40025
STAC2 SH3 and cysteine rich domain 2 2.40025
ODC1 ornithine decarboxylase 1 2.39874
OSCAR osteoclast associated, immunoglobulin-like receptor 2.38679
GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 2.38679
SLC38A10 solute carrier family 38, member 10 2.37967
FBXO40 F-box protein 40 2.36293
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 2.34624
MCM5 minichromosome maintenance complex component 5 2.31749
ZC3H8 zinc finger CCCH-type containing 8 2.31749
SETD1A SET domain containing 1A 2.31749
ESR1 estrogen receptor 1 2.28249
C22ORF15 chromosome 22 open reading frame 15 2.28249
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 2.25663
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 2.2184
SRP54 signal recognition particle 54kDa 2.2184
ZNF32 zinc finger protein 32 2.18305
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.1715
ILK integrin-linked kinase 2.16559
CNOT9 CCR4-NOT transcription complex subunit 9 2.16559
ATP5MG ATP synthase membrane subunit g 2.12335
TMEM18 transmembrane protein 18 2.12017
BCL6 B-cell CLL/lymphoma 6 2.11626
H1-3 H1.3 linker histone, cluster member 2.10768
PIH1D1 PIH1 domain containing 1 2.10324
HDGFL3 HDGF like 3 2.09795
RIPK2 receptor-interacting serine-threonine kinase 2 2.09795
NICOL1 NELL2 interacting cell ontogeny regulator 1 2.09795
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 2.07843
SENP8 SUMO/sentrin specific peptidase family member 8 2.07843
TACR1 tachykinin receptor 1 2.07473
TSPYL5 TSPY-like 5 2.07436
HOOK2 hook microtubule-tethering protein 2 2.07278
ZNF507 zinc finger protein 507 2.06005
STRAP serine/threonine kinase receptor associated protein 2.05909
TMEM101 transmembrane protein 101 2.05688
SDF2 stromal cell-derived factor 2 2.05688
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 2.05688
AP1B1 adaptor-related protein complex 1, beta 1 subunit 2.04494
TLCD4 TLC domain containing 4 2.04376
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 2.03848
TMEM209 transmembrane protein 209 2.0164
MBTPS2 membrane-bound transcription factor peptidase, site 2 2.01208
ZNF76 zinc finger protein 76 2.00003
JKAMP JNK1/MAPK8-associated membrane protein 2.00003

decreased expression

Symbol Name Standardized Value
SYT3 synaptotagmin III -3.04213
CYTIP cytohesin 1 interacting protein -3.04213
MICALL2 MICAL-like 2 -3.04213
VCX variable charge, X-linked -3.02479
TRPM8 transient receptor potential cation channel, subfamily M, member 8 -3.02479
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 -3.02479
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -3.02479
TULP2 tubby like protein 2 -3.02479
AVPR1A arginine vasopressin receptor 1A -3.02479
LRRC32 leucine rich repeat containing 32 -3.02479
FNDC8 fibronectin type III domain containing 8 -3.02479
SLC10A4 solute carrier family 10, member 4 -3.02479
FETUB fetuin B -3.02479
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 -3.02479
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) -3.02479
GLIPR1L2 GLI pathogenesis-related 1 like 2 -3.02479
ADH6 alcohol dehydrogenase 6 (class V) -3.02479
ETV7 ets variant 7 -3.02479
FAM110D family with sequence similarity 110, member D -3.02479
FKTN fukutin -3.02479
SCRT2 scratch family zinc finger 2 -3.02479
ZNF804B zinc finger protein 804B -3.02479
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -3.02479
GPR78 G protein-coupled receptor 78 -3.02479
C8ORF74 chromosome 8 open reading frame 74 -3.02479
DKK2 dickkopf WNT signaling pathway inhibitor 2 -3.02479
TEDC1 tubulin epsilon and delta complex 1 -3.02479
CLRN1 clarin 1 -3.02479
CRYBA1 crystallin, beta A1 -3.02479
TEX46 testis expressed 46 -3.02479
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 -3.02479
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.02479
CLCF1 cardiotrophin-like cytokine factor 1 -3.02479
ORM2 orosomucoid 2 -3.02479
OR2A42 olfactory receptor, family 2, subfamily A, member 42 -3.02479
LOC122455342 testis-specific serine/proline-rich protein -3.02479
LOC122526780 uncharacterized LOC122526780 -3.02479
CILP2 cartilage intermediate layer protein 2 -3.02479
CRYBA4 crystallin, beta A4 -3.02479
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 -3.02479
PLPP4 phospholipid phosphatase 4 -3.02479
CXCR4 chemokine (C-X-C motif) receptor 4 -3.02479
DEUP1 deuterosome assembly protein 1 -3.02479
CCDC22 coiled-coil domain containing 22 -2.94094
MAPK6 mitogen-activated protein kinase 6 -2.91584
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -2.85931
WDR35 WD repeat domain 35 -2.79219
CPTP ceramide-1-phosphate transfer protein -2.75363
TRIM3 tripartite motif containing 3 -2.67891
APCDD1 adenomatosis polyposis coli down-regulated 1 -2.66484
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -2.6515
PYY peptide YY -2.64908
RGS17 regulator of G-protein signaling 17 -2.59734
PMEL premelanosome protein -2.58226
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 -2.55668
ARID1A AT rich interactive domain 1A (SWI-like) -2.55268
TM2D3 TM2 domain containing 3 -2.54855
ARSA arylsulfatase A -2.53318
GSTM2 glutathione S-transferase mu 2 (muscle) -2.53318
IL18 interleukin 18 -2.53318
ZNF718 zinc finger protein 718 -2.51791
TMEM25 transmembrane protein 25 -2.51038
POFUT1 protein O-fucosyltransferase 1 -2.47043
BMPER BMP binding endothelial regulator -2.46207
PCYT1B phosphate cytidylyltransferase 1, choline, beta -2.43556
REPIN1 replication initiator 1 -2.42959
ST7 suppression of tumorigenicity 7 -2.42959
LEMD3 LEM domain containing 3 -2.42917
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 -2.37664
DPYSL3 dihydropyrimidinase-like 3 -2.35871
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -2.31749
EFHD1 EF-hand domain family, member D1 -2.31749
TTC1 tetratricopeptide repeat domain 1 -2.31641
SAMD4B sterile alpha motif domain containing 4B -2.29374
CARNMT1 carnosine N-methyltransferase 1 -2.28662
WAC WW domain containing adaptor with coiled-coil -2.28249
GLDN gliomedin -2.28017
SCAMP1 secretory carrier membrane protein 1 -2.25842
SIK2 salt-inducible kinase 2 -2.22001
RAP2C RAP2C, member of RAS oncogene family -2.2184
NXNL2 nucleoredoxin-like 2 -2.21455
CXCL17 chemokine (C-X-C motif) ligand 17 -2.21455
PCDHA5 protocadherin alpha 5 -2.21455
BMI1 BMI1 proto-oncogene, polycomb ring finger -2.19561
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.17899
SRPX sushi-repeat containing protein, X-linked -2.16559
LPCAT1 lysophosphatidylcholine acyltransferase 1 -2.16559
GYG1 glycogenin 1 -2.16222
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit -2.15444
SLC35E1 solute carrier family 35, member E1 -2.12796
ITPK1 inositol-tetrakisphosphate 1-kinase -2.12796
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) -2.12796
ARF1 ADP-ribosylation factor 1 -2.12006
AHRR aryl-hydrocarbon receptor repressor -2.11821
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 -2.07748
C8ORF88 chromosome 8 open reading frame 88 -2.05688
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 -2.05688
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.05688
AGO1 argonaute RISC catalytic component 1 -2.05688
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 -2.05688
CFAP144 cilia and flagella associated protein 144 -2.05688
BAAT bile acid CoA:amino acid N-acyltransferase -2.05688
ZNF324 zinc finger protein 324 -2.05688
SYNE1 spectrin repeat containing, nuclear envelope 1 -2.05081
UBASH3B ubiquitin associated and SH3 domain containing B -2.04985
HMGA2 high mobility group AT-hook 2 -2.0465
PTTG1IP pituitary tumor-transforming 1 interacting protein -2.0465
LMF1 lipase maturation factor 1 -2.0455
TTC27 tetratricopeptide repeat domain 27 -2.03872
INTS4 integrator complex subunit 4 -2.02189
COMTD1 catechol-O-methyltransferase domain containing 1 -2.02189
FBXL2 F-box and leucine-rich repeat protein 2 -2.0164
UNC45A unc-45 homolog A (C. elegans) -2.01525