SIK3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description SIK family kinase 3| (NCBI Entrez Gene Database, 23387)
External Link https://ncbi.nlm.nih.gov/gene/23387
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Genes

499 genes differentially expressed following the SIK3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center 0.0150017
PEG10 paternally expressed 10 0.0137912
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.0132626
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.0119054
VTCN1 V-set domain containing T cell activation inhibitor 1 0.0118601
PLAAT3 phospholipase A and acyltransferase 3 0.0118075
AMDHD2 amidohydrolase domain containing 2 0.0115222
MAMLD1 mastermind-like domain containing 1 0.0101368
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0100584
TFPI2 tissue factor pathway inhibitor 2 0.00978966
SCGB1D2 secretoglobin, family 1D, member 2 0.00945896
FOLR1 folate receptor 1 (adult) 0.00934198
FADS3 fatty acid desaturase 3 0.00922729
KRT19 keratin 19, type I 0.00908396
CAPG capping protein (actin filament), gelsolin-like 0.00892762
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00869035
SCGB2A1 secretoglobin, family 2A, member 1 0.00866294
ASRGL1 asparaginase like 1 0.0085597
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00851963
GOLGA8A golgin A8 family, member A 0.00849037
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00843819
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.00827422
AMIGO2 adhesion molecule with Ig-like domain 2 0.00823133
WASF1 WAS protein family, member 1 0.00804363
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.00804211
PERP PERP, TP53 apoptosis effector 0.00802923
ANXA4 annexin A4 0.00802146
CRABP2 cellular retinoic acid binding protein 2 0.00788236
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00782844
RBM47 RNA binding motif protein 47 0.00779637
LYN LYN proto-oncogene, Src family tyrosine kinase 0.00770156
PCLAF PCNA clamp associated factor 0.00765187
BTF3P11 basic transcription factor 3 pseudogene 11 0.00763786
PDCD10 programmed cell death 10 0.00754209
ADAM9 ADAM metallopeptidase domain 9 0.00753969
EYA2 EYA transcriptional coactivator and phosphatase 2 0.00750969
CST6 cystatin E/M 0.007446
ANPEP alanyl (membrane) aminopeptidase 0.00744066
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00741776
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.00740529
VAMP8 vesicle-associated membrane protein 8 0.00738724
CAV1 caveolin 1, caveolae protein, 22kDa 0.00735376
SLC38A1 solute carrier family 38, member 1 0.00733768
CLEC2B C-type lectin domain family 2, member B 0.00728438
DPP4 dipeptidyl-peptidase 4 0.00727785
GAS1 growth arrest-specific 1 0.00724705
EFHD1 EF-hand domain family, member D1 0.00723627
TMEM126B transmembrane protein 126B 0.0072262
RGS16 regulator of G-protein signaling 16 0.00721875
MXRA5 matrix-remodelling associated 5 0.00721327
BAD BCL2-associated agonist of cell death 0.00715017
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00712156
NT5E 5'-nucleotidase, ecto (CD73) 0.00708485
TACSTD2 tumor-associated calcium signal transducer 2 0.0070591
SCPEP1 serine carboxypeptidase 1 0.00703789
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.00701484
H1-2 H1.2 linker histone, cluster member 0.00700131
METTL7A methyltransferase like 7A 0.00698174
KRT7 keratin 7, type II 0.00695714
S100A10 S100 calcium binding protein A10 0.00695023
MMP11 matrix metallopeptidase 11 0.00693298
CALD1 caldesmon 1 0.00693215
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.00692023
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00689923
KRT17 keratin 17, type I 0.00689525
SELENOT selenoprotein T 0.00688065
ALB albumin 0.00686821
POSTN periostin, osteoblast specific factor 0.00685219
ERGIC2 ERGIC and golgi 2 0.00679396
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0067877
ADAM10 ADAM metallopeptidase domain 10 0.00675518
TRAM1 translocation associated membrane protein 1 0.00675451
CCNG2 cyclin G2 0.00673769
PODXL podocalyxin-like 0.00673725
RIN2 Ras and Rab interactor 2 0.00668364
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00665275
HTRA1 HtrA serine peptidase 1 0.00661232
RAB29 RAB29, member RAS oncogene family 0.00658433
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00657969
GPNMB glycoprotein (transmembrane) nmb 0.00654909
MN1 meningioma (disrupted in balanced translocation) 1 0.00653042
S100A4 S100 calcium binding protein A4 0.00653021
DEFB1 defensin, beta 1 0.00651668
C14ORF132 chromosome 14 open reading frame 132 0.00650883
TFRC transferrin receptor 0.00649892
LOX lysyl oxidase 0.0064713
NXN nucleoredoxin 0.00645997
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.00645166
SC5D sterol-C5-desaturase 0.00645078
VGLL1 vestigial-like family member 1 0.00644824
PANK3 pantothenate kinase 3 0.00641325
CTSV cathepsin V 0.00639874
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 0.0063938
S100A9 S100 calcium binding protein A9 0.00639203
RIDA reactive intermediate imine deaminase A homolog 0.00638867
KRT14 keratin 14, type I 0.00634693
HEBP2 heme binding protein 2 0.00634189
PEG3 paternally expressed 3 0.00634024
HSPA1A heat shock 70kDa protein 1A 0.00632404
S100A2 S100 calcium binding protein A2 0.00630661
NCK1 NCK adaptor protein 1 0.00630632
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00630461
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00627332
HIP1R huntingtin interacting protein 1 related 0.0062709
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 0.00624983
EMP1 epithelial membrane protein 1 0.006248
LEPROT leptin receptor overlapping transcript 0.00624006
HOXC6 homeobox C6 0.00621348
REXO2 RNA exonuclease 2 0.00620983
NVL nuclear VCP-like 0.00620887
ZNF83 zinc finger protein 83 0.00618831
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.006179
LAMP5 lysosomal-associated membrane protein family, member 5 0.00617169
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.00615477
ARMT1 acidic residue methyltransferase 1 0.00613902
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.00611505
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.00611478
IPO13 importin 13 0.0060717
PRNP prion protein 0.0060662
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00606389
NINJ2 ninjurin 2 0.00603342
HK2 hexokinase 2 0.00603031
USP3 ubiquitin specific peptidase 3 0.00601997
TPP2 tripeptidyl peptidase II 0.00601843
ZNF195 zinc finger protein 195 0.00600834
PLIN1 perilipin 1 0.00600824
AHNAK AHNAK nucleoprotein 0.00600586
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00597145
DEPTOR DEP domain containing MTOR-interacting protein 0.00593663
CCNA2 cyclin A2 0.00592469
ANXA3 annexin A3 0.00588799
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00588704
SGK1 serum/glucocorticoid regulated kinase 1 0.0058776
CNIH4 cornichon family AMPA receptor auxiliary protein 4 0.00587758
LTBP2 latent transforming growth factor beta binding protein 2 0.00585881
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00584807
PNN pinin, desmosome associated protein 0.00583232
MRPL13 mitochondrial ribosomal protein L13 0.00582672
GLRX glutaredoxin (thioltransferase) 0.00580964
EZR ezrin 0.00580629
RGCC regulator of cell cycle 0.00579878
ENY2 enhancer of yellow 2 homolog (Drosophila) 0.00579259
COL5A1 collagen, type V, alpha 1 0.00579191
NBPF10 neuroblastoma breakpoint family, member 10 0.0057879
KRT23 keratin 23, type I 0.00578322
LPPR1 lipid phosphate phosphatase-related protein type 1 0.00577176
MAPT microtubule-associated protein tau 0.00574694
MGLL monoglyceride lipase 0.00574371
TMED5 transmembrane emp24 protein transport domain containing 5 0.00573457
FXYD2 FXYD domain containing ion transport regulator 2 0.00571454
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00569731
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 0.00568446
GGT1 gamma-glutamyltransferase 1 0.00567874
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00567187
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.00566868
PLK2 polo-like kinase 2 0.00565611
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.00564428
KRT8 keratin 8, type II 0.00563052
AMOTL2 angiomotin like 2 0.00560314
CORO1C coronin, actin binding protein, 1C 0.00559828
VAMP7 vesicle-associated membrane protein 7 0.00558746
LAMA5 laminin, alpha 5 0.00557608
FTH1 ferritin, heavy polypeptide 1 0.0055692
UBXN4 UBX domain protein 4 0.00554433
RPS27L ribosomal protein S27-like 0.00553444
PRKCI protein kinase C, iota 0.00553224
APOA1 apolipoprotein A-I 0.00552655
ASS1 argininosuccinate synthase 1 0.00551361
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 0.00550904
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00550224
MMP7 matrix metallopeptidase 7 0.00550074
CTSD cathepsin D 0.00549252
EIF3E eukaryotic translation initiation factor 3, subunit E 0.00547679
TSPO translocator protein (18kDa) 0.00546733
ARHGAP29 Rho GTPase activating protein 29 0.0054508
NNT nicotinamide nucleotide transhydrogenase 0.00544247
IFI16 interferon, gamma-inducible protein 16 0.00541967
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 0.00541935
LDOC1 leucine zipper, down-regulated in cancer 1 0.00541872
RRAGC Ras-related GTP binding C 0.00539424
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 0.00537001
CDH16 cadherin 16, KSP-cadherin 0.00535213
SERINC1 serine incorporator 1 0.00534399
PLXNA1 plexin A1 0.00533431
CARMIL1 capping protein regulator and myosin 1 linker 1 0.00533155
PDZK1IP1 PDZK1 interacting protein 1 0.00531891
MFAP5 microfibrillar associated protein 5 0.00531079
MET MET proto-oncogene, receptor tyrosine kinase 0.00530728
WWC1 WW and C2 domain containing 1 0.00530467
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 0.00530406
EIF5B eukaryotic translation initiation factor 5B 0.00529772
VEGFB vascular endothelial growth factor B 0.00528486
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.00528283
APOA2 apolipoprotein A-II 0.00527538
CD58 CD58 molecule 0.00527498
TXNDC9 thioredoxin domain containing 9 0.00526098
RSL24D1 ribosomal L24 domain containing 1 0.00525044
SCP2 sterol carrier protein 2 0.00524913
PTK2B protein tyrosine kinase 2 beta 0.00524456
RAB9A RAB9A, member RAS oncogene family 0.00524396
KIF2A kinesin heavy chain member 2A 0.00524373
AMBP alpha-1-microglobulin/bikunin precursor 0.00521559
PROM1 prominin 1 0.00521411
CRYZ crystallin, zeta (quinone reductase) 0.0052107
TXN thioredoxin 0.00518975
CLTB clathrin, light chain B 0.0051865
NPM3 nucleophosmin/nucleoplasmin 3 0.00518531
COMP cartilage oligomeric matrix protein 0.00516052
ADCY1 adenylate cyclase 1 (brain) 0.00515456
IGFBP5 insulin-like growth factor binding protein 5 0.00515418
DYNLT1 dynein, light chain, Tctex-type 1 0.005153
CXCL8 chemokine (C-X-C motif) ligand 8 0.00515101
STXBP2 syntaxin binding protein 2 0.00514274
RARS1 arginyl-tRNA synthetase 1 0.00512049
KDM6A lysine (K)-specific demethylase 6A 0.00511927
HBZ hemoglobin, zeta 0.00510065
ACSL4 acyl-CoA synthetase long-chain family member 4 0.00509424
FNDC3B fibronectin type III domain containing 3B 0.00508064
VAV3 vav 3 guanine nucleotide exchange factor 0.0050714
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.00506694
EPS8L2 EPS8-like 2 0.00506489
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 0.00506456
MIR22HG MIR22 host gene 0.00506287
TAOK3 TAO kinase 3 0.00504591
ANXA1 annexin A1 0.0050403
DSP desmoplakin 0.00503614
RAB7A RAB7A, member RAS oncogene family 0.00502313
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1 0.00502154
ENAH enabled homolog (Drosophila) 0.00501073
HPN hepsin 0.0050106
CYB5R4 cytochrome b5 reductase 4 0.00501025
ANKRD12 ankyrin repeat domain 12 0.00501003
TMEM132A transmembrane protein 132A 0.00500169
L1CAM L1 cell adhesion molecule 0.00499297
SCGB2A2 secretoglobin, family 2A, member 2 0.00499004
PITX1 paired-like homeodomain 1 0.00498333
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.00497813
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 0.00497809
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00497304
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00497213
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.00496956
SPON2 spondin 2, extracellular matrix protein 0.00496312
HOXB2 homeobox B2 0.00495164
INHBB inhibin, beta B 0.00494959
GTF2A2 general transcription factor IIA, 2, 12kDa 0.00494504
TMEM243 transmembrane protein 243, mitochondrial 0.00494353
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.00493975
STS steroid sulfatase (microsomal), isozyme S 0.00493867
RABGGTB Rab geranylgeranyltransferase, beta subunit 0.0049355
RAP2C RAP2C, member of RAS oncogene family 0.00492207

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0219303
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0179709
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.0153527
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0151371
KDM5D lysine (K)-specific demethylase 5D -0.0141083
CHEK2 checkpoint kinase 2 -0.0127316
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.011856
PUF60 poly-U binding splicing factor 60KDa -0.0116734
COCH cochlin -0.0104264
H1-0 H1.0 linker histone -0.00984469
CLU clusterin -0.00974422
GPM6B glycoprotein M6B -0.00968204
NTS neurotensin -0.00966283
MBD1 methyl-CpG binding domain protein 1 -0.00964872
TARP TCR gamma alternate reading frame protein -0.00961058
PRUNE2 prune homolog 2 (Drosophila) -0.00938556
SNX11 sorting nexin 11 -0.00937803
C8ORF4 chromosome 8 open reading frame 4 -0.00910272
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00900604
GPX2 glutathione peroxidase 2 -0.00894426
DACH1 dachshund family transcription factor 1 -0.00893031
NID1 nidogen 1 -0.00887078
AKAP12 A kinase (PRKA) anchor protein 12 -0.00884799
DNASE1L3 deoxyribonuclease I-like 3 -0.00859625
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00848219
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00847385
MCOLN1 mucolipin 1 -0.00843479
PLN phospholamban -0.00835375
NIBAN1 niban apoptosis regulator 1 -0.00835293
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.0082453
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00824496
GSTT1 glutathione S-transferase theta 1 -0.00820812
SORBS1 sorbin and SH3 domain containing 1 -0.00819313
A2M alpha-2-macroglobulin -0.00812749
ACOT7 acyl-CoA thioesterase 7 -0.00811275
JADE2 jade family PHD finger 2 -0.00810249
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00805147
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00802232
PDE4D phosphodiesterase 4D, cAMP-specific -0.00801594
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00800535
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -0.00799076
CPA3 carboxypeptidase A3 (mast cell) -0.00793697
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00793032
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.00790217
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -0.00789121
ALCAM activated leukocyte cell adhesion molecule -0.00787836
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.00784651
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.00777187
FAR2 fatty acyl CoA reductase 2 -0.00775189
FBLN5 fibulin 5 -0.00774869
NEBL nebulette -0.00774577
PRMT1 protein arginine methyltransferase 1 -0.00763144
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00752512
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00752416
ANO10 anoctamin 10 -0.00751022
GPI glucose-6-phosphate isomerase -0.00746738
TM9SF3 transmembrane 9 superfamily member 3 -0.00740138
C1QA complement component 1, q subcomponent, A chain -0.00739725
STAB1 stabilin 1 -0.00736914
MYH11 myosin, heavy chain 11, smooth muscle -0.00734996
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00733378
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00733359
TSPAN8 tetraspanin 8 -0.00727789
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00725465
EFNB2 ephrin-B2 -0.00717288
VWF von Willebrand factor -0.0071616
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.00713486
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.0071089
LTF lactotransferrin -0.00705003
RNASE6 ribonuclease, RNase A family, k6 -0.00704983
GIMAP4 GTPase, IMAP family member 4 -0.00701081
TCF7 transcription factor 7 (T-cell specific, HMG-box) -0.00696743
CHGB chromogranin B -0.00692712
MOXD1 monooxygenase, DBH-like 1 -0.00686165
HBB hemoglobin, beta -0.00686061
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0068437
TRIM14 tripartite motif containing 14 -0.00681881
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -0.00681573
CH25H cholesterol 25-hydroxylase -0.00679602
DDIT4 DNA-damage-inducible transcript 4 -0.00675119
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -0.00674596
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 -0.00674204
WFDC1 WAP four-disulfide core domain 1 -0.00672582
ATP10B ATPase, class V, type 10B -0.00670541
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00665502
IFITM1 interferon induced transmembrane protein 1 -0.00651355
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -0.0065133
AQP1 aquaporin 1 (Colton blood group) -0.00651171
TLE4 transducin-like enhancer of split 4 -0.00649573
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.00649299
COL4A6 collagen, type IV, alpha 6 -0.00644205
AGTR1 angiotensin II receptor, type 1 -0.0063894
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -0.00638413
CD36 CD36 molecule (thrombospondin receptor) -0.00637167
PER2 period circadian clock 2 -0.00636763
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -0.00635667
C8ORF33 chromosome 8 open reading frame 33 -0.00634549
DHRS11 dehydrogenase/reductase (SDR family) member 11 -0.00634312
TENT5A terminal nucleotidyltransferase 5A -0.00633995
TGFBI transforming growth factor, beta-induced, 68kDa -0.00632803
MAGEA3 melanoma antigen family A3 -0.00631766
CLC Charcot-Leyden crystal galectin -0.00627799
KLF5 Kruppel-like factor 5 (intestinal) -0.00627059
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.0062366
LCK LCK proto-oncogene, Src family tyrosine kinase -0.00623549
C7 complement component 7 -0.00623328
H2AX H2A.X variant histone -0.00621095
CD52 CD52 molecule -0.00618807
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.006181
RETREG3 reticulophagy regulator family member 3 -0.00617803
ADCY3 adenylate cyclase 3 -0.00616805
MYLK myosin light chain kinase -0.00614669
DES desmin -0.00613109
DCXR dicarbonyl/L-xylulose reductase -0.00611076
WIF1 WNT inhibitory factor 1 -0.0061012
CYBRD1 cytochrome b reductase 1 -0.00609044
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00608014
FAM171A1 family with sequence similarity 171, member A1 -0.00607943
PCDH9 protocadherin 9 -0.00607502
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00607008
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00606257
CHPT1 choline phosphotransferase 1 -0.00603644
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00602632
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00602002
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -0.00599552
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00599453
ELANE elastase, neutrophil expressed -0.00599239
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.00597583
IL7R interleukin 7 receptor -0.00596253
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.0059574
CES1 carboxylesterase 1 -0.00594547
GIMAP6 GTPase, IMAP family member 6 -0.00593799
NFASC neurofascin -0.00593017
DCLK1 doublecortin-like kinase 1 -0.00592779
SRPX sushi-repeat containing protein, X-linked -0.00592689
DEXI Dexi homolog (mouse) -0.00592123
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00592078
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00591555
AQP3 aquaporin 3 (Gill blood group) -0.00591356
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00590997
RGS1 regulator of G-protein signaling 1 -0.00589166
DPYSL3 dihydropyrimidinase-like 3 -0.00588903
MMP12 matrix metallopeptidase 12 -0.00588366
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -0.00587943
TSPYL5 TSPY-like 5 -0.00585191
ANG angiogenin, ribonuclease, RNase A family, 5 -0.00584476
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00582468
TBX3 T-box 3 -0.00582232
SIDT2 SID1 transmembrane family, member 2 -0.00581657
PLVAP plasmalemma vesicle associated protein -0.0058114
HBD hemoglobin, delta -0.0058099
IL13RA2 interleukin 13 receptor, alpha 2 -0.00579193
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00578783
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.0057832
SFTPA2 surfactant protein A2 -0.00578283
EGR2 early growth response 2 -0.00577419
TUBA1A tubulin, alpha 1a -0.00574974
KLF9 Kruppel-like factor 9 -0.0057461
KRT20 keratin 20, type I -0.00572883
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -0.00572318
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00571944
SPRY2 sprouty homolog 2 (Drosophila) -0.00571603
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -0.00570959
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00570745
FGF13 fibroblast growth factor 13 -0.00567754
SPARCL1 SPARC-like 1 (hevin) -0.00567185
ACTG2 actin, gamma 2, smooth muscle, enteric -0.0056718
PRPF19 pre-mRNA processing factor 19 -0.00567177
SPAG16 sperm associated antigen 16 -0.00566105
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.0056365
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor -0.00563229
PIGT phosphatidylinositol glycan anchor biosynthesis, class T -0.00562527
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00562241
EDNRB endothelin receptor type B -0.00558496
AGR2 anterior gradient 2 -0.00557785
LARS1 leucyl-tRNA synthetase 1 -0.00556139
JAM3 junctional adhesion molecule 3 -0.00554914
NES nestin -0.00554819
CHI3L2 chitinase 3-like 2 -0.00554813
CBR3 carbonyl reductase 3 -0.00554173
PDLIM5 PDZ and LIM domain 5 -0.00553957
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -0.00552896
FTO fat mass and obesity associated -0.00552646
C1R complement component 1, r subcomponent -0.00552367
OTULINL OTU deubiquitinase with linear linkage specificity like -0.00550934
ACP5 acid phosphatase 5, tartrate resistant -0.005475
S100P S100 calcium binding protein P -0.00545852
AHNAK2 AHNAK nucleoprotein 2 -0.00545665
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -0.00544263
UQCRC1 ubiquinol-cytochrome c reductase core protein I -0.00544127
IL33 interleukin 33 -0.00543528
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.00541766
FABP7 fatty acid binding protein 7, brain -0.00540055
CFH complement factor H -0.00537791
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.00536887
ANXA6 annexin A6 -0.00536533
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -0.00535879
SYNM synemin, intermediate filament protein -0.00534951
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -0.0053465
ACE2 angiotensin I converting enzyme 2 -0.00533931
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.005339
CALCA calcitonin-related polypeptide alpha -0.00531921
SOX9 SRY (sex determining region Y)-box 9 -0.00531699
CD8A CD8a molecule -0.00530265
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0052975
SLCO2B1 solute carrier organic anion transporter family, member 2B1 -0.00529567
NRN1 neuritin 1 -0.00528956
CERS6 ceramide synthase 6 -0.00528502
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00528487
NBR1 neighbor of BRCA1 gene 1 -0.00528229
ZNF274 zinc finger protein 274 -0.0052756
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00527395
GRWD1 glutamate-rich WD repeat containing 1 -0.00525344
SLC44A4 solute carrier family 44, member 4 -0.00524909
PRTN3 proteinase 3 -0.00522289
DIAPH2 diaphanous-related formin 2 -0.00521745
C21ORF33 chromosome 21 open reading frame 33 -0.00520876
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -0.00520752
MAGED1 melanoma antigen family D1 -0.00520553
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -0.00519476
NELL2 NEL-like 2 (chicken) -0.0051878
PARN poly(A)-specific ribonuclease -0.00518336
STAC SH3 and cysteine rich domain -0.00518071
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -0.00517848
FOXG1 forkhead box G1 -0.00517235
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00516867
SEPP1 selenoprotein P, plasma, 1 -0.00516733
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) -0.00516435
SCRG1 stimulator of chondrogenesis 1 -0.00515226
DHCR7 7-dehydrocholesterol reductase -0.00513916
NEFH neurofilament, heavy polypeptide -0.00513852
COG7 component of oligomeric golgi complex 7 -0.00513847
FXYD3 FXYD domain containing ion transport regulator 3 -0.00511098
JAG1 jagged 1 -0.00510219
LAGE3 L antigen family, member 3 -0.00508735
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -0.00508509
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00507314
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 -0.00506166
CADM1 cell adhesion molecule 1 -0.00505996
MEPCE methylphosphate capping enzyme -0.00503667
HEPH hephaestin -0.00503071
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -0.00502764
SELE selectin E -0.0050239
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.00501144
SORBS2 sorbin and SH3 domain containing 2 -0.00499942
BABAM2 BRISC and BRCA1 A complex member 2 -0.00499588
NR1I2 nuclear receptor subfamily 1, group I, member 2 -0.00498836
TOB2 transducer of ERBB2, 2 -0.00498745
GIMAP5 GTPase, IMAP family member 5 -0.0049675