SIKE1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description suppressor of IKBKE 1|SIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 80143)
External Link http://www.ncbi.nlm.nih.gov/gene/80143
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Genes

89 interacting proteins for SIKE1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ANKLE2 ankyrin repeat and LEM domain containing 2
APC adenomatous polyposis coli
CCSER2 coiled-coil serine-rich protein 2
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CDC37 cell division cycle 37
CENPJ centromere protein J
CEP170B centrosomal protein 170B
CEP192 centrosomal protein 192kDa
CNTROB centrobin, centrosomal BRCA2 interacting protein
COL4A5 collagen, type IV, alpha 5
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTNBP2 cortactin binding protein 2
CTTNBP2NL CTTNBP2 N-terminal like
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DYNLL1 dynein, light chain, LC8-type 1
DYNLL2 dynein, light chain, LC8-type 2
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EMD emerin
FGFR1OP2 FGFR1 oncogene partner 2
FKBP15 FK506 binding protein 15, 133kDa
FMNL1 formin-like 1
FRYL FRY-like
GFOD1 glucose-fructose oxidoreductase domain containing 1
GOLGA2 golgin A2
HDAC6 histone deacetylase 6
IGBP1 immunoglobulin (CD79A) binding protein 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
KIAA1522 KIAA1522
KIAA1671 KIAA1671
MAP1B microtubule-associated protein 1B
MAP1S microtubule-associated protein 1S
MOB4 MOB family member 4, phocein
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NRF1 nuclear respiratory factor 1
OFD1 oral-facial-digital syndrome 1
PARVG parvin, gamma
PBK PDZ binding kinase
PDCD10 programmed cell death 10
PFDN2 prefoldin subunit 2
PFDN5 prefoldin subunit 5
PFDN6 prefoldin subunit 6
PGAM5 phosphoglycerate mutase family member 5
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPME1 protein phosphatase methylesterase 1
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PROSER2 proline and serine rich 2
PRR14L proline rich 14-like
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RUVBL2 RuvB-like AAA ATPase 2
SACK1B scaffolding CK1 anchoring protein B
SGOL1 shugoshin-like 1 (S. pombe)
SLMAP sarcolemma associated protein
STK24 serine/threonine kinase 24
STK25 serine/threonine kinase 25
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
STRIP1 striatin interacting protein 1
STRIP2 striatin interacting protein 2
STRN striatin, calmodulin binding protein
STRN3 striatin, calmodulin binding protein 3
STRN4 striatin, calmodulin binding protein 4
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK1 TAO kinase 1
TBK1 TANK-binding kinase 1
TCP1 t-complex 1
TRAF3IP3 TRAF3 interacting protein 3
UBC ubiquitin C
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VBP1 von Hippel-Lindau binding protein 1