| Dataset | CORUM Protein Complexes |
| Category | structural or functional annotations |
| Type | protein complex |
| Description | A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins. (Gene Ontology, GO_0016580) |
| External Link | http://mips.helmholtz-muenchen.de/genre/proj/corum/complexdetails.html?id=54 |
| Similar Terms | |
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7 proteins in the SIN3 complex protein complex from the CORUM Protein Complexes dataset.
