SIN3A Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SIN3 transcription regulator family member A|The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 25942)
Similar Terms
Downloads & Tools

Genes

352 genes differentially expressed following the SIN3A gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CHADL chondroadherin-like 2.59345
SLC15A5 solute carrier family 15, member 5 2.59345
FETUB fetuin B 2.59345
OLIG3 oligodendrocyte transcription factor 3 2.59345
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 2.59345
SCNN1G sodium channel, non voltage gated 1 gamma subunit 2.59345
GPR21 G protein-coupled receptor 21 2.59345
ANKRD34A ankyrin repeat domain 34A 2.59345
OTUD6A OTU deubiquitinase 6A 2.59345
BIRC3 baculoviral IAP repeat containing 3 2.59345
POSTN periostin, osteoblast specific factor 2.59345
PQBP1 polyglutamine binding protein 1 2.59345
PAX3 paired box 3 2.59345
FBXL8 F-box and leucine-rich repeat protein 8 2.59345
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 2.59345
ENTHD1 ENTH domain containing 1 2.59345
KLRK1 killer cell lectin-like receptor subfamily K, member 1 2.59345
CELF3 CUGBP, Elav-like family member 3 2.59345
CD1C CD1c molecule 2.59345
CELA3A chymotrypsin-like elastase family, member 3A 2.59345
HES7 hes family bHLH transcription factor 7 2.59345
NCF2 neutrophil cytosolic factor 2 2.59345
OR10A4 olfactory receptor, family 10, subfamily A, member 4 2.59345
TRPV3 transient receptor potential cation channel, subfamily V, member 3 2.59345
RAPSN receptor-associated protein of the synapse 2.59345
SNPH syntaphilin 2.59345
AVP arginine vasopressin 2.59345
OVCH1 ovochymase 1 2.59345
CSNK2A3 casein kinase 2, alpha 3 polypeptide 2.59345
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 2.59345
RTP1 receptor (chemosensory) transporter protein 1 2.59345
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 2.59345
CFAP54 cilia and flagella associated 54 2.59345
TMEM132C transmembrane protein 132C 2.59345
BOLA2 bolA family member 2 2.59345
SNAI2 snail family zinc finger 2 2.59345
ADH6 alcohol dehydrogenase 6 (class V) 2.59345
PTK6 protein tyrosine kinase 6 2.59345
TPM2 tropomyosin 2 (beta) 2.59345
PSCA prostate stem cell antigen 2.59345
CPB2 carboxypeptidase B2 (plasma) 2.59345
ACVRL1 activin A receptor type II-like 1 2.59345
MEIKIN meiotic kinetochore factor 2.59345
C8ORF74 chromosome 8 open reading frame 74 2.59345
STX3 syntaxin 3 2.59345
DLL4 delta-like 4 (Drosophila) 2.59345
GNRHR gonadotropin-releasing hormone receptor 2.59345
LBX2 ladybird homeobox 2 2.59345
ANXA2R annexin A2 receptor 2.59345
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.59345
CIMIP2A ciliary microtubule inner protein 2A 2.59345
ADGRG3 adhesion G protein-coupled receptor G3 2.59345
OR51E1 olfactory receptor, family 51, subfamily E, member 1 2.59345
FMO2 flavin containing monooxygenase 2 (non-functional) 2.59345
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H 2.59345
MIOX myo-inositol oxygenase 2.59345
TTR transthyretin 2.59345
DOK2 docking protein 2, 56kDa 2.59345
RASD1 RAS, dexamethasone-induced 1 2.59345
MAGIX MAGI family member, X-linked 2.59345
OR7D2 olfactory receptor, family 7, subfamily D, member 2 2.59345
HBG2 hemoglobin, gamma G 2.59345
GBP1 guanylate binding protein 1, interferon-inducible 2.59345
MAP3K4-AS1 MAP3K4 antisense RNA 1 2.59345
LOC124903233 uncharacterized LOC124903233 2.59345
PEAK3 PEAK family member 3 2.59345
IQCN IQ motif containing N 2.59345
FLACC1 flagellum associated containing coiled-coil domains 1 2.59345
RTL9 retrotransposon Gag like 9 2.59345
CBLIF cobalamin binding intrinsic factor 2.59345
MATCAP2 microtubule associated tyrosine carboxypeptidase 2 2.59345
TENT4A terminal nucleotidyltransferase 4A 2.59345
PHF24 PHD finger protein 24 2.59345
PARVG parvin, gamma 2.59345
PRDM6 PR domain containing 6 2.59345
CNTN5 contactin 5 2.59345
ACMSD aminocarboxymuconate semialdehyde decarboxylase 2.59345
LTBP2 latent transforming growth factor beta binding protein 2 2.59345
PCDHB10 protocadherin beta 10 2.59345
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 2.59345
PRB2 proline-rich protein BstNI subfamily 2 2.59345
POMC proopiomelanocortin 2.59345
KLHL31 kelch-like family member 31 2.59345
ACTL10 actin-like 10 2.59345
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 2.59345
SPDYE6 speedy/RINGO cell cycle regulator family member E6 2.59345
CRLF2 cytokine receptor-like factor 2 2.59345
CD48 CD48 molecule 2.59345
LRRN4CL LRRN4 C-terminal like 2.59345
ACE2 angiotensin I converting enzyme 2 2.59345
WNT9B wingless-type MMTV integration site family, member 9B 2.59345
SAMD11 sterile alpha motif domain containing 11 2.59345
RASAL3 RAS protein activator like 3 2.59345
SLAMF6 SLAM family member 6 2.59345
AWAT1 acyl-CoA wax alcohol acyltransferase 1 2.59345
ZNF575 zinc finger protein 575 2.59345
NAAA N-acylethanolamine acid amidase 2.59345
NPNT nephronectin 2.59345
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.59345
RBP4 retinol binding protein 4, plasma 2.59345
DMTN dematin actin binding protein 2.59345
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 2.59345
BTNL8 butyrophilin-like 8 2.59345
CPSF4L cleavage and polyadenylation specific factor 4-like 2.59345
KLF4 Kruppel-like factor 4 (gut) 2.59345
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.59345
PEBP4 phosphatidylethanolamine-binding protein 4 2.59345
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 2.59345
CCNDBP1 cyclin D-type binding-protein 1 2.59345
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 2.59345
C6ORF163 chromosome 6 open reading frame 163 2.59345
KCNK7 potassium channel, two pore domain subfamily K, member 7 2.59345
HPD 4-hydroxyphenylpyruvate dioxygenase 2.59345
MAGEB17 melanoma antigen family B17 2.59345
SPRN shadow of prion protein homolog (zebrafish) 2.59345
CIDEA cell death-inducing DFFA-like effector a 2.59345
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 2.59345
KRT10 keratin 10, type I 2.59345
MBOAT4 membrane bound O-acyltransferase domain containing 4 2.59345
UBE2D1 ubiquitin-conjugating enzyme E2D 1 2.59345
EBF2 early B-cell factor 2 2.59345
EBF4 early B-cell factor 4 2.59345
TMSB4X thymosin beta 4, X-linked 2.59345
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 2.59345
DEFB135 defensin, beta 135 2.59345
KLHL10 kelch-like family member 10 2.59345
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 2.59345
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.59345
HLA-DMB major histocompatibility complex, class II, DM beta 2.59345
PCDH20 protocadherin 20 2.59345
LRRN4 leucine rich repeat neuronal 4 2.59345
DRC1 dynein regulatory complex subunit 1 2.59345
STRC stereocilin 2.59345
LOXHD1 lipoxygenase homology domains 1 2.59345
C8B complement component 8, beta polypeptide 2.59345
EPHA10 EPH receptor A10 2.59345
PCDHGA7 protocadherin gamma subfamily A, 7 2.59345
CRHR2 corticotropin releasing hormone receptor 2 2.59345
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 2.59345
COX7B2 cytochrome c oxidase subunit VIIb2 2.59345
C17ORF99 chromosome 17 open reading frame 99 2.59345
IL1B interleukin 1, beta 2.59345
DHH desert hedgehog 2.59345
KLK5 kallikrein-related peptidase 5 2.59345
RSF1 remodeling and spacing factor 1 2.59345
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 2.59345
CD177 CD177 molecule 2.59345
ECM1 extracellular matrix protein 1 2.59345
ROM1 retinal outer segment membrane protein 1 2.59345
TRPM5 transient receptor potential cation channel, subfamily M, member 5 2.59345
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 2.59345
ITPKA inositol-trisphosphate 3-kinase A 2.59345
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 2.59345
TRPM1 transient receptor potential cation channel, subfamily M, member 1 2.59345
MT1M metallothionein 1M 2.59345
AZU1 azurocidin 1 2.59345
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 2.59345
ANGPTL6 angiopoietin-like 6 2.59345
NGDN neuroguidin, EIF4E binding protein 2.59345
GPRC5D G protein-coupled receptor, class C, group 5, member D 2.59345
CLPSL1 colipase-like 1 2.59345
IFITM10 interferon induced transmembrane protein 10 2.59345
TSKS testis-specific serine kinase substrate 2.59345
ABHD1 abhydrolase domain containing 1 2.59345
TMIGD3 transmembrane and immunoglobulin domain containing 3 2.59345
MRGPRX3 MAS-related GPR, member X3 2.59345
AGBL4 ATP/GTP binding protein-like 4 2.59345
CLCNKA chloride channel, voltage-sensitive Ka 2.59345
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 2.59345
C1ORF105 chromosome 1 open reading frame 105 2.59345
POU3F3 POU class 3 homeobox 3 2.59345
ZC3H11B zinc finger CCCH-type containing 11B pseudogene 2.59345
C5ORF46 chromosome 5 open reading frame 46 2.59345
EPO erythropoietin 2.59345
COL12A1 collagen, type XII, alpha 1 2.59345
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.59345
DEFB134 defensin, beta 134 2.59345
TRAPPC9 trafficking protein particle complex 9 2.58426
ACTB actin, beta 2.58426
EFTUD2 elongation factor Tu GTP binding domain containing 2 2.58426
EIF5A2 eukaryotic translation initiation factor 5A2 2.55842
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.54916
DUSP19 dual specificity phosphatase 19 2.5394
ADGRD2 adhesion G protein-coupled receptor D2 2.47544
NTMT2 N-terminal Xaa-Pro-Lys N-methyltransferase 2 2.47544
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 2.47544
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.47544
GBA1 glucosylceramidase beta 1 2.47544
PDE11A phosphodiesterase 11A 2.47544
GYG2 glycogenin 2 2.47431
MYZAP myocardial zonula adherens protein 2.4726
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 2.4726
ZC2HC1A zinc finger, C2HC-type containing 1A 2.39624
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 2.38965
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4 2.38384
GLRX3 glutaredoxin 3 2.36986
PLA2G15 phospholipase A2, group XV 2.33973
SAMM50 SAMM50 sorting and assembly machinery component 2.33622
NOTCH4 notch 4 2.33509
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like 2.31246
SCCPDH saccharopine dehydrogenase (putative) 2.29756
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22 2.28876
RPL23A ribosomal protein L23a 2.26388
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 2.26388
ASTN2 astrotactin 2 2.25903
KDF1 keratinocyte differentiation factor 1 2.24871
ICE2 interactor of little elongation complex ELL subunit 2 2.24634
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 2.24267
SRP54 signal recognition particle 54kDa 2.22253
CCDC122 coiled-coil domain containing 122 2.22253
TIGD7 tigger transposable element derived 7 2.18127
ZMAT1 zinc finger, matrin-type 1 2.17587
TMEM147 transmembrane protein 147 2.17504
RALBP1 ralA binding protein 1 2.15755
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 2.15132
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 2.15132
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 2.12865
SLC25A46 solute carrier family 25, member 46 2.0989
MCAM melanoma cell adhesion molecule 2.09436
PARD6G par-6 family cell polarity regulator gamma 2.09391
MTBP MDM2 binding protein 2.08381
MBTD1 mbt domain containing 1 2.08204
MZT1 mitotic spindle organizing protein 1 2.07892
RPS15 ribosomal protein S15 2.07892
STARD13 StAR-related lipid transfer (START) domain containing 13 2.07525
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) 2.07151
ATXN2 ataxin 2 2.07083
N4BP2 NEDD4 binding protein 2 2.02334
VAMP3 vesicle-associated membrane protein 3 2.01553
MAP2K3 mitogen-activated protein kinase kinase 3 2.01369
IFI27L2 interferon, alpha-inducible protein 27-like 2 2.01004

decreased expression

Symbol Name Standardized Value
TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like -2.59345
PLEKHN1 pleckstrin homology domain containing, family N member 1 -2.59345
PTPRD protein tyrosine phosphatase, receptor type, D -2.59345
KLF11 Kruppel-like factor 11 -2.59345
CALB2 calbindin 2 -2.59345
C19ORF73 chromosome 19 open reading frame 73 -2.59345
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -2.59345
TNXB tenascin XB -2.59345
UGCG UDP-glucose ceramide glucosyltransferase -2.59345
ACOXL acyl-CoA oxidase-like -2.59345
FADS1 fatty acid desaturase 1 -2.59345
CHRM2 cholinergic receptor, muscarinic 2 -2.59345
ZFYVE19 zinc finger, FYVE domain containing 19 -2.59345
NINL ninein-like -2.59345
RNPEP arginyl aminopeptidase (aminopeptidase B) -2.59345
NPIPB2 nuclear pore complex interacting protein family member B2 -2.59345
PCNX2 pecanex 2 -2.59345
UNC5C unc-5 homolog C (C. elegans) -2.59345
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -2.59345
CGAS cyclic GMP-AMP synthase -2.59345
CFAP418 cilia and flagella associated protein 418 -2.59345
H1-1 H1.1 linker histone, cluster member -2.59345
PKD2L2 polycystic kidney disease 2-like 2 -2.59345
TEAD4 TEA domain family member 4 -2.59345
NPIPB6 nuclear pore complex interacting protein family, member B6 -2.59345
INPP5J inositol polyphosphate-5-phosphatase J -2.58426
H3C11 H3 clustered histone 11 -2.58426
IKZF3 IKAROS family zinc finger 3 (Aiolos) -2.47431
UPP2 uridine phosphorylase 2 -2.47431
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -2.47431
KIF12 kinesin family member 12 -2.47431
CXCL17 chemokine (C-X-C motif) ligand 17 -2.47431
LRMDA leucine rich melanocyte differentiation associated -2.47431
STYK1 serine/threonine/tyrosine kinase 1 -2.47431
RASD2 RASD family, member 2 -2.47431
TP53TG5 TP53 target 5 -2.47431
LOX lysyl oxidase -2.47431
LAMA4 laminin, alpha 4 -2.47431
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 -2.47431
TCL1B T-cell leukemia/lymphoma 1B -2.47431
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 -2.47431
SUSD2 sushi domain containing 2 -2.47431
CATSPERT catsper channel auxiliary subunit tau -2.47431
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 -2.47431
CD164L2 CD164 sialomucin-like 2 -2.47431
PRSS36 protease, serine, 36 -2.47431
CA7 carbonic anhydrase VII -2.47431
LYG1 lysozyme G-like 1 -2.47431
RAD21L1 RAD21-like 1 (S. pombe) -2.47431
INSM1 insulinoma-associated 1 -2.47431
FGR FGR proto-oncogene, Src family tyrosine kinase -2.47431
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A -2.47431
NRIP2 nuclear receptor interacting protein 2 -2.47431
SEC14L6 SEC14-like 6 (S. cerevisiae) -2.47431
ANKRD65 ankyrin repeat domain 65 -2.47431
CAMK2B calcium/calmodulin-dependent protein kinase II beta -2.47431
SNX31 sorting nexin 31 -2.47431
TIGD3 tigger transposable element derived 3 -2.47431
LAMB3 laminin, beta 3 -2.47431
GOLGA8H golgin A8 family, member H -2.47431
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 -2.47431
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 -2.47431
LRRC26 leucine rich repeat containing 26 -2.47431
FCN3 ficolin (collagen/fibrinogen domain containing) 3 -2.47431
TTBK1 tau tubulin kinase 1 -2.47431
CREG1 cellular repressor of E1A-stimulated genes 1 -2.46457
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) -2.45618
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 -2.44791
CAPN7 calpain 7 -2.42774
ARHGAP23 Rho GTPase activating protein 23 -2.42324
PDE3A phosphodiesterase 3A, cGMP-inhibited -2.41962
RASIP1 Ras interacting protein 1 -2.4186
GNG2 guanine nucleotide binding protein (G protein), gamma 2 -2.40616
BICD1 bicaudal D homolog 1 (Drosophila) -2.40616
SPAST spastin -2.40374
OAZ2 ornithine decarboxylase antizyme 2 -2.40374
NUP62 nucleoporin 62kDa -2.38384
ASF1A anti-silencing function 1A histone chaperone -2.33509
PAQR3 progestin and adipoQ receptor family member III -2.31338
SLC16A13 solute carrier family 16, member 13 -2.29086
CRAT carnitine O-acetyltransferase -2.29086
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 -2.29086
LRRC17 leucine rich repeat containing 17 -2.29086
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 -2.29003
STAT4 signal transducer and activator of transcription 4 -2.29003
ZNF550 zinc finger protein 550 -2.29003
RAD51C RAD51 paralog C -2.26975
ATRX alpha thalassemia/mental retardation syndrome X-linked -2.26388
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) -2.24873
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -2.24871
WDTC1 WD and tetratricopeptide repeats 1 -2.24267
ZNF205 zinc finger protein 205 -2.23675
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 -2.20686
TESK1 testis-specific kinase 1 -2.20007
DAPK1 death-associated protein kinase 1 -2.20007
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) -2.20007
SOD2 superoxide dismutase 2, mitochondrial -2.1894
CFD complement factor D (adipsin) -2.18637
PSME4 proteasome (prosome, macropain) activator subunit 4 -2.15617
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 -2.15262
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A -2.15132
CLNS1A chloride channel, nucleotide-sensitive, 1A -2.13297
EFNA1 ephrin-A1 -2.1297
NR2C2AP nuclear receptor 2C2-associated protein -2.12732
LRRC4C leucine rich repeat containing 4C -2.12488
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae) -2.12488
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -2.11847
DCP1A decapping mRNA 1A -2.09391
ZNF827 zinc finger protein 827 -2.09182
MTMR6 myotubularin related protein 6 -2.07892
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 -2.07796
MSH2 mutS homolog 2 -2.07638
U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4 -2.07308
NINJ2 ninjurin 2 -2.04626
NENF neudesin neurotrophic factor -2.04601
KDM5A lysine (K)-specific demethylase 5A -2.0322
TMEM178A transmembrane protein 178A -2.02334
BRAT1 BRCA1-associated ATM activator 1 -2.01369
SAMHD1 SAM domain and HD domain 1 -2.01004
LMBRD2 LMBR1 domain containing 2 -2.0096
CSRNP3 cysteine-serine-rich nuclear protein 3 -2.00032