SIN3A Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description SIN3 transcription regulator family member A|The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 25942)
External Link https://ncbi.nlm.nih.gov/gene/25942
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Genes

500 genes differentially expressed following the SIN3A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
LTF lactotransferrin 0.020021
ANO10 anoctamin 10 0.0197846
DSP desmoplakin 0.0189483
S100A7 S100 calcium binding protein A7 0.0187649
S100A9 S100 calcium binding protein A9 0.018697
CSTA cystatin A (stefin A) 0.0182677
KRT14 keratin 14, type I 0.017705
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.017047
TUBB2A tubulin, beta 2A class IIa 0.0162136
CA2 carbonic anhydrase II 0.0161031
KRT5 keratin 5, type II 0.0159574
PUF60 poly-U binding splicing factor 60KDa 0.0158721
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.0154951
JMJD6 jumonji domain containing 6 0.0147956
S100A8 S100 calcium binding protein A8 0.0145454
NDRG1 N-myc downstream regulated 1 0.0143678
ARG1 arginase 1 0.0138599
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0135894
KRT16 keratin 16, type I 0.0135635
KRT6B keratin 6B, type II 0.0135081
PMEL premelanosome protein 0.0134907
PI3 peptidase inhibitor 3, skin-derived 0.0131802
FAM162A family with sequence similarity 162, member A 0.013154
KRT6A keratin 6A, type II 0.0131457
MMP9 matrix metallopeptidase 9 0.0130741
SPINK5 serine peptidase inhibitor, Kazal type 5 0.0130716
PITX3 paired-like homeodomain 3 0.0130399
CARMIL1 capping protein regulator and myosin 1 linker 1 0.0128427
AMDHD2 amidohydrolase domain containing 2 0.0128238
PERP PERP, TP53 apoptosis effector 0.0127026
LOR loricrin 0.0126534
PEG10 paternally expressed 10 0.0124481
SPRR1B small proline-rich protein 1B 0.0122916
CALML5 calmodulin-like 5 0.0122011
S100A2 S100 calcium binding protein A2 0.0121487
DCT dopachrome tautomerase 0.0121087
TYRP1 tyrosinase-related protein 1 0.0119717
DEFB1 defensin, beta 1 0.0118443
PAX5 paired box 5 0.0117401
SIRT3 sirtuin 3 0.0115976
CLTB clathrin, light chain B 0.0115746
CST7 cystatin F (leukocystatin) 0.0115701
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.0115691
AUTS2 autism susceptibility candidate 2 0.01149
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.0114361
KRT81 keratin 81, type II 0.011419
TYR tyrosinase 0.011232
DEFA4 defensin, alpha 4, corticostatin 0.0112038
CAMP cathelicidin antimicrobial peptide 0.0111835
HBD hemoglobin, delta 0.0107136
FTH1 ferritin, heavy polypeptide 1 0.0107016
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.0106216
LYPD3 LY6/PLAUR domain containing 3 0.010593
TCL1A T-cell leukemia/lymphoma 1A 0.0104795
FXYD2 FXYD domain containing ion transport regulator 2 0.0104457
BTG3 BTG family, member 3 0.0102997
CALML3 calmodulin-like 3 0.0102046
FOXG1 forkhead box G1 0.0101766
TMEM45A transmembrane protein 45A 0.0101012
KRT17 keratin 17, type I 0.0100762
SPRR1A small proline-rich protein 1A 0.010037
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00993691
POU2AF1 POU class 2 associating factor 1 0.00992749
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.00989028
LITAF lipopolysaccharide-induced TNF factor 0.00987376
KRT1 keratin 1, type II 0.00987257
QPCT glutaminyl-peptide cyclotransferase 0.0098639
MAL mal, T-cell differentiation protein 0.00980558
BPI bactericidal/permeability-increasing protein 0.00978668
TUBA4A tubulin, alpha 4a 0.00977007
H1-0 H1.0 linker histone 0.00975202
CD19 CD19 molecule 0.00972256
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.00969607
CD9 CD9 molecule 0.00967794
ELANE elastase, neutrophil expressed 0.00962297
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.00948894
CD8A CD8a molecule 0.00935927
SEC13 SEC13 homolog (S. cerevisiae) 0.00928642
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.0092825
CST6 cystatin E/M 0.00926313
DSG1 desmoglein 1 0.00925026
CTSG cathepsin G 0.00913553
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00906433
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.0090296
ALDOA aldolase A, fructose-bisphosphate 0.00901394
CD79A CD79a molecule, immunoglobulin-associated alpha 0.00899714
PGLYRP1 peptidoglycan recognition protein 1 0.00899398
FGFR1 fibroblast growth factor receptor 1 0.0089929
CRISP3 cysteine-rich secretory protein 3 0.00897398
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.00896727
CIAO3 cytosolic iron-sulfur assembly component 3 0.00893828
EREG epiregulin 0.00891901
S100P S100 calcium binding protein P 0.00881377
CLCA2 chloride channel accessory 2 0.00880824
MAST3 microtubule associated serine/threonine kinase 3 0.00870008
DLK1 delta-like 1 homolog (Drosophila) 0.00867038
KRT10 keratin 10, type I 0.00866712
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 0.0086641
ENO1 enolase 1, (alpha) 0.0086388
RHCG Rh family, C glycoprotein 0.008605
CCN3 cellular communication network factor 3 0.0085876
ALAS2 5'-aminolevulinate synthase 2 0.00851202
CXCL13 chemokine (C-X-C motif) ligand 13 0.00846035
TTC3 tetratricopeptide repeat domain 3 0.0084529
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.00845155
CD59 CD59 molecule, complement regulatory protein 0.00842641
CLDN8 claudin 8 0.00830763
MGAM maltase-glucoamylase 0.00830736
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.00826627
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00826215
CDSN corneodesmosin 0.00825984
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00823762
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.00821456
PGK1 phosphoglycerate kinase 1 0.00820443
MPC1 mitochondrial pyruvate carrier 1 0.00820292
RUNX3 runt-related transcription factor 3 0.00814934
HSPH1 heat shock 105kDa/110kDa protein 1 0.00814396
KRT2 keratin 2, type II 0.00813466
MMP8 matrix metallopeptidase 8 0.00812773
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.00808267
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.008078
ACOT7 acyl-CoA thioesterase 7 0.00803934
MALT1 MALT1 paracaspase 0.00794823
AZU1 azurocidin 1 0.00793497
FGFR3 fibroblast growth factor receptor 3 0.00792303
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.00790178
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.00789577
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.00789374
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00786583
NVL nuclear VCP-like 0.00786508
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.00784842
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00782892
CORO1C coronin, actin binding protein, 1C 0.00780545
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 0.00779698
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.00774645
RCAN1 regulator of calcineurin 1 0.0077284
CD177 CD177 molecule 0.00768043
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.00762541
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00761939
NPC2 Niemann-Pick disease, type C2 0.00761094
DAD1 defender against cell death 1 0.00757714
ABHD5 abhydrolase domain containing 5 0.00756145
VCAM1 vascular cell adhesion molecule 1 0.00753084
SST somatostatin 0.00752446
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.00751693
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 0.00749863
SIX2 SIX homeobox 2 0.00746353
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00745307
HMOX1 heme oxygenase 1 0.00743624
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.0074307
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 0.00741948
PRTN3 proteinase 3 0.0073648
GPM6B glycoprotein M6B 0.00735708
CYB5A cytochrome b5 type A (microsomal) 0.00733749
CKAP4 cytoskeleton-associated protein 4 0.00732516
RNF167 ring finger protein 167 0.00731895
TRIM29 tripartite motif containing 29 0.00731859
LSP1 lymphocyte-specific protein 1 0.00726796
BCL2A1 BCL2-related protein A1 0.00726228
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 0.00724997
GPR137B G protein-coupled receptor 137B 0.00724494
PRSS8 protease, serine, 8 0.00723513
NADSYN1 NAD synthetase 1 0.00722313
ZNF91 zinc finger protein 91 0.00721879
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 0.00720815
DSC1 desmocollin 1 0.00720466
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00718574
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.00717339
KYNU kynureninase 0.00716919
RPP40 ribonuclease P/MRP 40kDa subunit 0.00715158
KLF6 Kruppel-like factor 6 0.00712662
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00711831
EAF2 ELL associated factor 2 0.0071049
TATDN2 TatD DNase domain containing 2 0.00708678
SLPI secretory leukocyte peptidase inhibitor 0.00706865
FKBP11 FK506 binding protein 11, 19 kDa 0.00706768
KDM4C lysine (K)-specific demethylase 4C 0.00704532
ZG16 zymogen granule protein 16 0.00702847
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00702
DUSP2 dual specificity phosphatase 2 0.00697904
DUSP14 dual specificity phosphatase 14 0.00696106
GRN granulin 0.00695237
MYO5A myosin VA (heavy chain 12, myoxin) 0.00693843
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 0.0069379
CCR7 chemokine (C-C motif) receptor 7 0.00693696
CDHR1 cadherin-related family member 1 0.00693573
AFP alpha-fetoprotein 0.00692444
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 0.00692054
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00691666
IL1R2 interleukin 1 receptor, type II 0.00691422
AVPI1 arginine vasopressin-induced 1 0.00691374
RAB32 RAB32, member RAS oncogene family 0.00690723
PABPC3 poly(A) binding protein, cytoplasmic 3 0.00689697
MCOLN1 mucolipin 1 0.00688207
SEPP1 selenoprotein P, plasma, 1 0.00687469
MAP7 microtubule-associated protein 7 0.00684555
GPNMB glycoprotein (transmembrane) nmb 0.00684195
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00680422
GOLT1B golgi transport 1B 0.00679563
CDA cytidine deaminase 0.00679105
LGALS2 lectin, galactoside-binding, soluble, 2 0.00675934
WDR1 WD repeat domain 1 0.00675536
TUFT1 tuftelin 1 0.00673514
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00673427
MLANA melan-A 0.00672344
KCMF1 potassium channel modulatory factor 1 0.0066823
GPI glucose-6-phosphate isomerase 0.00666769
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00666531
ANPEP alanyl (membrane) aminopeptidase 0.00665907
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 0.00665134
LY6D lymphocyte antigen 6 complex, locus D 0.00664882
PLAGL1 pleiomorphic adenoma gene-like 1 0.00664791
RGS20 regulator of G-protein signaling 20 0.00663314
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.00662424
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.00661997
STK17A serine/threonine kinase 17a 0.00661651
SFN stratifin 0.006603
IL7R interleukin 7 receptor 0.0065925
PDCD10 programmed cell death 10 0.00657919
HACD2 3-hydroxyacyl-CoA dehydratase 2 0.00657664
ARL8B ADP-ribosylation factor-like 8B 0.00656458
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.00656079
LCE2B late cornified envelope 2B 0.00654447
PFKP phosphofructokinase, platelet 0.00652543
PDPK1 3-phosphoinositide dependent protein kinase 1 0.00652002
TPM4 tropomyosin 4 0.00649886
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00649806
SOSTDC1 sclerostin domain containing 1 0.00648891
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.00647508
IVL involucrin 0.00647082
CA12 carbonic anhydrase XII 0.00646797
IBSP integrin-binding sialoprotein 0.00646448
CXCR3 chemokine (C-X-C motif) receptor 3 0.00646238
GDI2 GDP dissociation inhibitor 2 0.00644248
PRAME preferentially expressed antigen in melanoma 0.00643395
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.00642948
COG7 component of oligomeric golgi complex 7 0.00642
RRAGC Ras-related GTP binding C 0.00641612
SLC45A2 solute carrier family 45, member 2 0.00639799
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 0.00639247
PLIN3 perilipin 3 0.00638127
KLK7 kallikrein-related peptidase 7 0.00637393
MPO myeloperoxidase 0.00637349
SDHAF1 succinate dehydrogenase complex assembly factor 1 0.00636858
RETN resistin 0.0063581
ATOX1 antioxidant 1 copper chaperone 0.0063449
ASPH aspartate beta-hydroxylase 0.00634423
ODC1 ornithine decarboxylase 1 0.00634201
LEFTY1 left-right determination factor 1 0.00633047
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00628289

decreased expression

Symbol Name Standardized Value
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0263493
MGP matrix Gla protein -0.0254568
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0212189
IFI27 interferon, alpha-inducible protein 27 -0.0196764
AGR2 anterior gradient 2 -0.0187137
ISG15 ISG15 ubiquitin-like modifier -0.0180705
ADGRF5 adhesion G protein-coupled receptor F5 -0.0179442
CFI complement factor I -0.0178494
ARHGAP29 Rho GTPase activating protein 29 -0.0176167
IFI44L interferon-induced protein 44-like -0.0166191
SPARCL1 SPARC-like 1 (hevin) -0.0163846
VWF von Willebrand factor -0.0160614
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.0156461
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.015618
CD93 CD93 molecule -0.0155516
IFITM1 interferon induced transmembrane protein 1 -0.0153884
MX1 MX dynamin-like GTPase 1 -0.0153685
SFRP4 secreted frizzled-related protein 4 -0.0153015
NPY1R neuropeptide Y receptor Y1 -0.0150651
RGS5 regulator of G-protein signaling 5 -0.0150639
IFI44 interferon-induced protein 44 -0.0149111
IGF1 insulin-like growth factor 1 (somatomedin C) -0.0148223
IFI6 interferon, alpha-inducible protein 6 -0.0147992
AQP1 aquaporin 1 (Colton blood group) -0.0147217
ZFPM2 zinc finger protein, FOG family member 2 -0.0145378
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0145109
ANXA1 annexin A1 -0.014359
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.0141001
CHRDL1 chordin-like 1 -0.0140541
TMEM100 transmembrane protein 100 -0.013884
MYH11 myosin, heavy chain 11, smooth muscle -0.013799
BST2 bone marrow stromal cell antigen 2 -0.0137573
GIMAP6 GTPase, IMAP family member 6 -0.0136958
AKAP12 A kinase (PRKA) anchor protein 12 -0.0135935
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.0135134
IRS1 insulin receptor substrate 1 -0.0134943
PLN phospholamban -0.0134641
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.0131941
COL3A1 collagen, type III, alpha 1 -0.013166
PTGIS prostaglandin I2 (prostacyclin) synthase -0.013155
FILIP1L filamin A interacting protein 1-like -0.013057
CFH complement factor H -0.0129074
RSAD2 radical S-adenosyl methionine domain containing 2 -0.0128732
TMEM176B transmembrane protein 176B -0.0128559
CD163 CD163 molecule -0.0128494
FRZB frizzled-related protein -0.0128033
PDLIM3 PDZ and LIM domain 3 -0.0127172
ASPN asporin -0.0126531
CES1 carboxylesterase 1 -0.0125683
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.012505
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.0124948
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.0124912
CAV1 caveolin 1, caveolae protein, 22kDa -0.0123336
MXRA5 matrix-remodelling associated 5 -0.0123329
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0123084
GOLGA8H golgin A8 family, member H -0.0122603
ARID4A AT rich interactive domain 4A (RBP1-like) -0.0122462
MSLN mesothelin -0.0121555
PDGFC platelet derived growth factor C -0.0121444
OLFM1 olfactomedin 1 -0.0120681
CHN2 chimerin 2 -0.0119105
ZBTB20 zinc finger and BTB domain containing 20 -0.0118498
ESR1 estrogen receptor 1 -0.0118195
FHL1 four and a half LIM domains 1 -0.011814
TSPAN8 tetraspanin 8 -0.0117873
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.0117647
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.0116601
GATA6 GATA binding protein 6 -0.0115798
CFB complement factor B -0.0115768
C8ORF4 chromosome 8 open reading frame 4 -0.0115461
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -0.0115063
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.0114902
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.0114449
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.0114148
GUSB glucuronidase, beta -0.0114146
CCNA2 cyclin A2 -0.0113424
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -0.0113272
STON1 stonin 1 -0.0113189
MT1E metallothionein 1E -0.0112176
PLAT plasminogen activator, tissue -0.0112062
CD302 CD302 molecule -0.0111895
NLGN4X neuroligin 4, X-linked -0.0111541
CLEC2B C-type lectin domain family 2, member B -0.0110842
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0110738
LGALS1 lectin, galactoside-binding, soluble, 1 -0.011069
TRIM14 tripartite motif containing 14 -0.0110596
IFI16 interferon, gamma-inducible protein 16 -0.0110371
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.0109578
GIMAP4 GTPase, IMAP family member 4 -0.0109129
TMSB15A thymosin beta 15a -0.0108921
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.0108762
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.0108306
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.0108038
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -0.0107871
XIC X chromosome inactivation center -0.0107648
MTUS1 microtubule associated tumor suppressor 1 -0.0107469
DPYD dihydropyrimidine dehydrogenase -0.0107453
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.0106836
EDNRA endothelin receptor type A -0.0106831
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.01067
SORD sorbitol dehydrogenase -0.0106469
MYO5C myosin VC -0.0106321
DYNLL1 dynein, light chain, LC8-type 1 -0.0105685
RHOBTB3 Rho-related BTB domain containing 3 -0.0105612
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0105479
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0103917
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.0103447
FSTL1 follistatin-like 1 -0.0102443
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.0101823
PBX1 pre-B-cell leukemia homeobox 1 -0.0101747
ENPEP glutamyl aminopeptidase (aminopeptidase A) -0.010147
ACTA2 actin, alpha 2, smooth muscle, aorta -0.0101391
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled -0.0101283
IRF9 interferon regulatory factor 9 -0.0101268
SAMD4A sterile alpha motif domain containing 4A -0.0100527
XAF1 XIAP associated factor 1 -0.0100352
ASS1 argininosuccinate synthase 1 -0.0100119
BGN biglycan -0.00993547
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.00990185
GRK5 G protein-coupled receptor kinase 5 -0.0099007
CDH5 cadherin 5, type 2 (vascular endothelium) -0.00989344
APOLD1 apolipoprotein L domain containing 1 -0.00988005
HSPB8 heat shock 22kDa protein 8 -0.00986762
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.009862
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00976972
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00975128
MYOF myoferlin -0.00973024
LIPG lipase, endothelial -0.00972352
C7 complement component 7 -0.00972286
CPVL carboxypeptidase, vitellogenic-like -0.00970463
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00966876
THBS4 thrombospondin 4 -0.00966781
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.0096432
GALC galactosylceramidase -0.00964229
PODXL podocalyxin-like -0.00963473
NID2 nidogen 2 (osteonidogen) -0.00960421
IFITM3 interferon induced transmembrane protein 3 -0.00959978
TRIM22 tripartite motif containing 22 -0.00959575
SYNM synemin, intermediate filament protein -0.00957798
APLNR apelin receptor -0.00955811
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00953991
MECOM MDS1 and EVI1 complex locus -0.00950752
DCN decorin -0.0094285
SLCO1B3 solute carrier organic anion transporter family, member 1B3 -0.00942726
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00939483
MYLK myosin light chain kinase -0.009367
KRT19 keratin 19, type I -0.00932873
HOXC6 homeobox C6 -0.00931126
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00931022
MX2 MX dynamin-like GTPase 2 -0.00929555
NT5E 5'-nucleotidase, ecto (CD73) -0.00927782
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00924365
TSPAN13 tetraspanin 13 -0.00922959
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00920006
GBP1 guanylate binding protein 1, interferon-inducible -0.00919452
MYBPC1 myosin binding protein C, slow type -0.00918132
MYRF myelin regulatory factor -0.00917082
NEFH neurofilament, heavy polypeptide -0.00914326
KLHL41 kelch-like family member 41 -0.00914047
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00910973
DAPK1 death-associated protein kinase 1 -0.00909718
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00909316
TNNT1 troponin T type 1 (skeletal, slow) -0.0090614
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -0.00903855
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 -0.00902564
CDC20 cell division cycle 20 -0.0090162
VCAN versican -0.00901135
TSPAN7 tetraspanin 7 -0.00899089
NDNF neuron-derived neurotrophic factor -0.00898551
HIP1 huntingtin interacting protein 1 -0.00897706
ADIRF adipogenesis regulatory factor -0.00896409
C2CD5 C2 calcium-dependent domain containing 5 -0.00894601
CCN2 cellular communication network factor 2 -0.00890544
KANK2 KN motif and ankyrin repeat domains 2 -0.00889707
DUT deoxyuridine triphosphatase -0.00887383
MGLL monoglyceride lipase -0.00886123
NUP85 nucleoporin 85kDa -0.00885789
FLT1 fms-related tyrosine kinase 1 -0.00884392
DUSP5 dual specificity phosphatase 5 -0.00881876
TNNC1 troponin C type 1 (slow) -0.00879941
LDB2 LIM domain binding 2 -0.00875458
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00875215
HOPX HOP homeobox -0.00873364
RHOBTB1 Rho-related BTB domain containing 1 -0.00872652
LUM lumican -0.00871431
TAGLN transgelin -0.00869542
GUSBP3 glucuronidase, beta pseudogene 3 -0.00867817
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.0086741
PDLIM5 PDZ and LIM domain 5 -0.00866448
HOXB6 homeobox B6 -0.00866026
COL14A1 collagen, type XIV, alpha 1 -0.00865702
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00860011
PCDH17 protocadherin 17 -0.00859184
TENM1 teneurin transmembrane protein 1 -0.00856606
ZNF22 zinc finger protein 22 -0.00851785
IL33 interleukin 33 -0.00851346
MMP7 matrix metallopeptidase 7 -0.00849963
ABLIM1 actin binding LIM protein 1 -0.00846239
C1R complement component 1, r subcomponent -0.00844767
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00844194
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -0.0084249
COL15A1 collagen, type XV, alpha 1 -0.00840883
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -0.00840198
AHR aryl hydrocarbon receptor -0.00838873
CLIC5 chloride intracellular channel 5 -0.00836917
SAMHD1 SAM domain and HD domain 1 -0.00834496
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00831106
MSMB microseminoprotein, beta- -0.00830252
NELL1 NEL-like 1 (chicken) -0.00826724
TCF12 transcription factor 12 -0.0082579
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -0.00824518
RTP4 receptor (chemosensory) transporter protein 4 -0.00819615
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00818389
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.00815459
LHFP lipoma HMGIC fusion partner -0.00813124
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.00809268
ANOS1 anosmin 1 -0.00808846
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -0.00808069
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.00804377
RUFY3 RUN and FYVE domain containing 3 -0.00803192
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -0.00802739
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 -0.00800485
MERTK MER proto-oncogene, tyrosine kinase -0.00799491
DCHS1 dachsous cadherin-related 1 -0.00798891
CALCRL calcitonin receptor-like -0.00795619
COL1A2 collagen, type I, alpha 2 -0.00795388
PDGFRL platelet-derived growth factor receptor-like -0.00795007
SLC35E2B solute carrier family 35, member E2B -0.00792363
MET MET proto-oncogene, receptor tyrosine kinase -0.00792065
SMPX small muscle protein, X-linked -0.0078795
ACTG2 actin, gamma 2, smooth muscle, enteric -0.0078745
CTSK cathepsin K -0.00786342
C3 complement component 3 -0.00785754
PLXDC1 plexin domain containing 1 -0.00784377
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00783703
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -0.00782656
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.00782636
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00781223
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.00778151
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.0077593
AMOTL2 angiomotin like 2 -0.00775557
BTG2 BTG family, member 2 -0.00774171
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -0.00772717
PCTP phosphatidylcholine transfer protein -0.00771762
COL10A1 collagen, type X, alpha 1 -0.00769512
MYOT myotilin -0.00768832
MTMR11 myotubularin related protein 11 -0.00768785
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.00767163
ANXA6 annexin A6 -0.00767064
PLSCR1 phospholipid scramblase 1 -0.00766433