| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | signal-regulatory protein alpha|The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 140885) |
| External Link | https://ncbi.nlm.nih.gov/gene/140885 |
| Similar Terms | |
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499 genes differentially expressed following the SIRPA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0254865 |
| CA2 | carbonic anhydrase II | 0.0135403 |
| HBB | hemoglobin, beta | 0.0100973 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00933413 |
| AK4 | adenylate kinase 4 | 0.00901558 |
| IFI44 | interferon-induced protein 44 | 0.00845393 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00844473 |
| LYPLA1 | lysophospholipase I | 0.00839791 |
| MRPL19 | mitochondrial ribosomal protein L19 | 0.00832871 |
| ARG1 | arginase 1 | 0.00825025 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0081314 |
| WDR61 | WD repeat domain 61 | 0.0080954 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00808268 |
| RPA3 | replication protein A3, 14kDa | 0.00788031 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0077441 |
| MYO1C | myosin IC | 0.00772579 |
| MBD1 | methyl-CpG binding domain protein 1 | 0.00770288 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00763742 |
| TYRP1 | tyrosinase-related protein 1 | 0.00756342 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00755499 |
| EVI2A | ecotropic viral integration site 2A | 0.00740574 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00740447 |
| MAL | mal, T-cell differentiation protein | 0.0073978 |
| IFI44L | interferon-induced protein 44-like | 0.00739003 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00734831 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.00733117 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00725276 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00719353 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00719147 |
| ATF3 | activating transcription factor 3 | 0.0071791 |
| ANO10 | anoctamin 10 | 0.00716676 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00700114 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 0.0069935 |
| PEX2 | peroxisomal biogenesis factor 2 | 0.00699295 |
| SKP1 | S-phase kinase-associated protein 1 | 0.00686158 |
| BTG3 | BTG family, member 3 | 0.00685525 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.00684378 |
| HAL | histidine ammonia-lyase | 0.00682964 |
| TMEM14A | transmembrane protein 14A | 0.00679393 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00677278 |
| NSG1 | neuron specific gene family member 1 | 0.00671853 |
| THY1 | Thy-1 cell surface antigen | 0.00668637 |
| KIFAP3 | kinesin-associated protein 3 | 0.00667504 |
| AKIP1 | A kinase (PRKA) interacting protein 1 | 0.0066518 |
| SYNGR3 | synaptogyrin 3 | 0.0066025 |
| TMEM38B | transmembrane protein 38B | 0.00659956 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00659025 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.00655341 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00654598 |
| ATG5 | autophagy related 5 | 0.0065409 |
| SST | somatostatin | 0.00652165 |
| MAGT1 | magnesium transporter 1 | 0.00651229 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 0.00650973 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.00650392 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00649855 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00649035 |
| SLN | sarcolipin | 0.00647116 |
| CD9 | CD9 molecule | 0.00646651 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00645535 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00642027 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00630168 |
| S100A9 | S100 calcium binding protein A9 | 0.00629927 |
| EGR3 | early growth response 3 | 0.0062961 |
| S100A2 | S100 calcium binding protein A2 | 0.00629101 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00624257 |
| MRPL17 | mitochondrial ribosomal protein L17 | 0.00622659 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | 0.0061991 |
| THBS1 | thrombospondin 1 | 0.00619651 |
| TMEM50B | transmembrane protein 50B | 0.00612761 |
| MYBPC1 | myosin binding protein C, slow type | 0.00611973 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.00611873 |
| IL10RB | interleukin 10 receptor, beta | 0.00611476 |
| RPL39L | ribosomal protein L39-like | 0.00610752 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.0060889 |
| KRT1 | keratin 1, type II | 0.00606531 |
| CCK | cholecystokinin | 0.0060593 |
| HAX1 | HCLS1 associated protein X-1 | 0.00600937 |
| IFI35 | interferon-induced protein 35 | 0.0060035 |
| LSM1 | LSM1, U6 small nuclear RNA associated | 0.00599407 |
| S100A7 | S100 calcium binding protein A7 | 0.00597065 |
| TSPAN6 | tetraspanin 6 | 0.00594109 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00593514 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00591082 |
| COPS4 | COP9 signalosome subunit 4 | 0.00589708 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00587609 |
| CALML5 | calmodulin-like 5 | 0.00585129 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00585123 |
| VAMP5 | vesicle-associated membrane protein 5 | 0.00581426 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00578706 |
| TRIM5 | tripartite motif containing 5 | 0.00577499 |
| SELENOW | selenoprotein W | 0.0057686 |
| NSL1 | NSL1, MIS12 kinetochore complex component | 0.0057667 |
| PRDX4 | peroxiredoxin 4 | 0.00576537 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.0057651 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00574903 |
| PPID | peptidylprolyl isomerase D | 0.00574324 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00573475 |
| FOXG1 | forkhead box G1 | 0.00573176 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 0.00573137 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00572975 |
| C11ORF58 | chromosome 11 open reading frame 58 | 0.00570233 |
| PSPH | phosphoserine phosphatase | 0.0056976 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.005688 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00566605 |
| CD86 | CD86 molecule | 0.00566213 |
| DCK | deoxycytidine kinase | 0.00564946 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 0.00564308 |
| FGGY | FGGY carbohydrate kinase domain containing | 0.0056176 |
| TMEM14B | transmembrane protein 14B | 0.00561557 |
| ZNF200 | zinc finger protein 200 | 0.00558633 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00556878 |
| CCNA2 | cyclin A2 | 0.00556262 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00554534 |
| CLDND1 | claudin domain containing 1 | 0.00553905 |
| PRSS21 | protease, serine, 21 (testisin) | 0.00551685 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00548734 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00546411 |
| COMMD8 | COMM domain containing 8 | 0.00545781 |
| DAZAP2 | DAZ associated protein 2 | 0.0054506 |
| CST7 | cystatin F (leukocystatin) | 0.0054433 |
| ELP3 | elongator acetyltransferase complex subunit 3 | 0.00544246 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00544152 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00543229 |
| SDF2 | stromal cell-derived factor 2 | 0.00542685 |
| MED7 | mediator complex subunit 7 | 0.00542042 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00542028 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0054159 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00540098 |
| GLO1 | glyoxalase I | 0.00539991 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00536471 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00536067 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00535645 |
| ENO1 | enolase 1, (alpha) | 0.00535414 |
| PGK1 | phosphoglycerate kinase 1 | 0.00535004 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 0.00530627 |
| GPR65 | G protein-coupled receptor 65 | 0.00530415 |
| ATOX1 | antioxidant 1 copper chaperone | 0.00528468 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.00524806 |
| PAH | phenylalanine hydroxylase | 0.00524778 |
| PLP1 | proteolipid protein 1 | 0.00523822 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00523561 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.00523492 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | 0.00522031 |
| GPR137B | G protein-coupled receptor 137B | 0.00521918 |
| MRS2 | MRS2 magnesium transporter | 0.00521135 |
| RPS5 | ribosomal protein S5 | 0.00521074 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | 0.00520271 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00520237 |
| IL1R2 | interleukin 1 receptor, type II | 0.00517638 |
| GUCY2C | guanylate cyclase 2C | 0.0051741 |
| TRIM21 | tripartite motif containing 21 | 0.00516713 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A | 0.00516604 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.00516322 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | 0.00516122 |
| TPM4 | tropomyosin 4 | 0.00513685 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00513471 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial | 0.00513223 |
| TP53TG1 | TP53 target 1 (non-protein coding) | 0.00512976 |
| TXNDC9 | thioredoxin domain containing 9 | 0.0051223 |
| ASF1A | anti-silencing function 1A histone chaperone | 0.00511886 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00511766 |
| CCND2 | cyclin D2 | 0.00509648 |
| DEFB1 | defensin, beta 1 | 0.00509503 |
| ATP5G3 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) | 0.00509147 |
| MAT2B | methionine adenosyltransferase II, beta | 0.00508252 |
| ERGIC2 | ERGIC and golgi 2 | 0.00505244 |
| CCNE2 | cyclin E2 | 0.0050469 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0050367 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00503365 |
| RCAN1 | regulator of calcineurin 1 | 0.00503234 |
| CEL | carboxyl ester lipase | 0.00502915 |
| POLB | polymerase (DNA directed), beta | 0.00502671 |
| HIKESHI | heat shock protein nuclear import factor hikeshi | 0.00502349 |
| GRAMD1C | GRAM domain containing 1C | 0.00501811 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 0.00501323 |
| CLEC2D | C-type lectin domain family 2, member D | 0.00501193 |
| GOLGA7 | golgin A7 | 0.00501082 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00501073 |
| NEK7 | NIMA-related kinase 7 | 0.00499791 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00497571 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 | 0.00495857 |
| LRRC17 | leucine rich repeat containing 17 | 0.00495742 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 | 0.00494784 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | 0.00494512 |
| DCTPP1 | dCTP pyrophosphatase 1 | 0.00493837 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.00491007 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.00490307 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00488898 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0048832 |
| ABI2 | abl-interactor 2 | 0.00488286 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | 0.00487828 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00487725 |
| MED28 | mediator complex subunit 28 | 0.0048753 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.00487449 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.00485944 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 0.00485697 |
| MMP9 | matrix metallopeptidase 9 | 0.0048545 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.00485115 |
| GUK1 | guanylate kinase 1 | 0.00484703 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.00484107 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00482678 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00482477 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.0048216 |
| NUP37 | nucleoporin 37kDa | 0.00481423 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 | 0.00481028 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.00480323 |
| TOX | thymocyte selection-associated high mobility group box | 0.00479948 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00477907 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00477677 |
| PENK | proenkephalin | 0.00477333 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 | 0.00477069 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00476863 |
| AK5 | adenylate kinase 5 | 0.00476748 |
| CHMP5 | charged multivesicular body protein 5 | 0.00476268 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00475945 |
| TSNAX | translin-associated factor X | 0.00475845 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00475817 |
| MREG | melanoregulin | 0.00475434 |
| ACP6 | acid phosphatase 6, lysophosphatidic | 0.00474122 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | 0.00474105 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00473508 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | 0.00472152 |
| MED6 | mediator complex subunit 6 | 0.00471466 |
| ANXA3 | annexin A3 | 0.00470473 |
| ZNF267 | zinc finger protein 267 | 0.00470376 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00470104 |
| PRKCH | protein kinase C, eta | 0.00469927 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00469859 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00469484 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein | 0.00469463 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.004693 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.00468413 |
| PCTP | phosphatidylcholine transfer protein | 0.00468399 |
| PHTF2 | putative homeodomain transcription factor 2 | 0.0046762 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00466169 |
| TSLIG2 | tRNA splicing ligase complex subunit 2 | 0.00465355 |
| ZNHIT3 | zinc finger, HIT-type containing 3 | 0.00464482 |
| COLEC11 | collectin sub-family member 11 | 0.00463794 |
| EREG | epiregulin | 0.00463444 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | 0.00463336 |
| POPDC3 | popeye domain containing 3 | 0.00463013 |
| MLF1 | myeloid leukemia factor 1 | 0.00462492 |
| TRAF1 | TNF receptor-associated factor 1 | 0.0046241 |
| WIF1 | WNT inhibitory factor 1 | 0.00461484 |
| COMMD10 | COMM domain containing 10 | 0.00460399 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.00459988 |
| FADD | Fas (TNFRSF6)-associated via death domain | 0.00459171 |
| RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) | 0.00458965 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.00458765 |
| SLFN12 | schlafen family member 12 | 0.00458524 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -0.0187728 |
| MAP7 | microtubule-associated protein 7 | -0.0143115 |
| TFF1 | trefoil factor 1 | -0.0118844 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0118547 |
| PROM1 | prominin 1 | -0.0113893 |
| PCDH9 | protocadherin 9 | -0.0110942 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.0108834 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0107121 |
| NID2 | nidogen 2 (osteonidogen) | -0.0104918 |
| LAMB1 | laminin, beta 1 | -0.0103784 |
| PMP22 | peripheral myelin protein 22 | -0.0103396 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00956204 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00946967 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00946194 |
| DCN | decorin | -0.00937864 |
| LUM | lumican | -0.00936191 |
| KRT19 | keratin 19, type I | -0.00921035 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0091725 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.0089538 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00890712 |
| GOLGA8H | golgin A8 family, member H | -0.00885189 |
| FASN | fatty acid synthase | -0.00862575 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.0086055 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00856166 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00852823 |
| GOLGA8A | golgin A8 family, member A | -0.00840756 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -0.00831306 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | -0.00830809 |
| CTBP2 | C-terminal binding protein 2 | -0.00827607 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00824962 |
| STC1 | stanniocalcin 1 | -0.00820355 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00817776 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00816623 |
| OLFM4 | olfactomedin 4 | -0.00803472 |
| PCP4 | Purkinje cell protein 4 | -0.0080192 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00796647 |
| RBPMS | RNA binding protein with multiple splicing | -0.00782392 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00776192 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00775855 |
| MXRA5 | matrix-remodelling associated 5 | -0.00774628 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.0077069 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00768006 |
| MGP | matrix Gla protein | -0.00767968 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00767551 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00762947 |
| PLXNC1 | plexin C1 | -0.0075969 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00758594 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.00755815 |
| MMP1 | matrix metallopeptidase 1 | -0.00755733 |
| RGS5 | regulator of G-protein signaling 5 | -0.00751685 |
| AEBP1 | AE binding protein 1 | -0.00751391 |
| MGLL | monoglyceride lipase | -0.00749168 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00748665 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00746416 |
| REEP1 | receptor accessory protein 1 | -0.00745943 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | -0.00745484 |
| G0S2 | G0/G1 switch 2 | -0.00742837 |
| APOD | apolipoprotein D | -0.0072958 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00729382 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00725845 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00719456 |
| ASPN | asporin | -0.00717808 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.00712813 |
| CUX1 | cut-like homeobox 1 | -0.00712305 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00709622 |
| EFHD2 | EF-hand domain family, member D2 | -0.00702814 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00683809 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.00683755 |
| TGM2 | transglutaminase 2 | -0.00678538 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00678479 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0066875 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00667746 |
| FHL1 | four and a half LIM domains 1 | -0.0066329 |
| REG1A | regenerating islet-derived 1 alpha | -0.00661394 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00659329 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00659014 |
| GAS1 | growth arrest-specific 1 | -0.00657164 |
| TLE5 | TLE family member 5, transcriptional modulator | -0.00655604 |
| GPX3 | glutathione peroxidase 3 | -0.00648629 |
| TLN1 | talin 1 | -0.00647373 |
| POSTN | periostin, osteoblast specific factor | -0.00645487 |
| BRD2 | bromodomain containing 2 | -0.00642039 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00639486 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.0063838 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.0063633 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00632757 |
| UBE2S | ubiquitin-conjugating enzyme E2S | -0.00632287 |
| INSR | insulin receptor | -0.0062879 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00628475 |
| TLE2 | transducin-like enhancer of split 2 | -0.00627734 |
| LYZ | lysozyme | -0.00627619 |
| SNX1 | sorting nexin 1 | -0.00626314 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00623724 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00623275 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.00623258 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00614901 |
| ANGPTL2 | angiopoietin-like 2 | -0.00612445 |
| CHGB | chromogranin B | -0.00609438 |
| IGF2R | insulin-like growth factor 2 receptor | -0.00604559 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00603785 |
| PEG10 | paternally expressed 10 | -0.00602997 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00602984 |
| AOC3 | amine oxidase, copper containing 3 | -0.00602164 |
| RTN1 | reticulon 1 | -0.00598488 |
| NAPA | N-ethylmaleimide-sensitive factor attachment protein, alpha | -0.00597829 |
| TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) | -0.00595189 |
| CHRDL1 | chordin-like 1 | -0.0059467 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00593641 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -0.00593138 |
| DGKZ | diacylglycerol kinase, zeta | -0.00592329 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00592161 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -0.00591972 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00590769 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00590753 |
| IRS2 | insulin receptor substrate 2 | -0.00590102 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00587435 |
| DPP4 | dipeptidyl-peptidase 4 | -0.00586136 |
| KIAA0930 | KIAA0930 | -0.00585225 |
| CES1 | carboxylesterase 1 | -0.00584628 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00582374 |
| TXLNA | taxilin alpha | -0.00582253 |
| PLXNB2 | plexin B2 | -0.00582146 |
| ELAC2 | elaC ribonuclease Z 2 | -0.00581852 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.00581823 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00580406 |
| PLCB4 | phospholipase C, beta 4 | -0.00580149 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | -0.0057705 |
| PLIN1 | perilipin 1 | -0.00575599 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 | -0.00571798 |
| AGR2 | anterior gradient 2 | -0.0056999 |
| REG3A | regenerating islet-derived 3 alpha | -0.00569701 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00568195 |
| CDC34 | cell division cycle 34 | -0.00565714 |
| CFD | complement factor D (adipsin) | -0.00564105 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00562185 |
| PNMA8A | PNMA family member 8A | -0.00560254 |
| TSPO | translocator protein (18kDa) | -0.00559786 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00558977 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00558761 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.00556306 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | -0.00555408 |
| PTCH1 | patched 1 | -0.00554959 |
| SETBP1 | SET binding protein 1 | -0.00553401 |
| JMJD1C | jumonji domain containing 1C | -0.00552597 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.00551985 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.00551847 |
| XYLT1 | xylosyltransferase I | -0.0054775 |
| SRRT | serrate, RNA effector molecule | -0.00547744 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.00547132 |
| KRT18 | keratin 18, type I | -0.00546837 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.00545572 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0054551 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0054429 |
| ZIC1 | Zic family member 1 | -0.00544048 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.00544026 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00541925 |
| NOTCH2NL | notch 2 N-terminal like | -0.00541492 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00541306 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.00541178 |
| SVIL | supervillin | -0.00538703 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | -0.00536742 |
| TPCN1 | two pore segment channel 1 | -0.00536098 |
| DUOX2 | dual oxidase 2 | -0.00532967 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00532886 |
| PLXND1 | plexin D1 | -0.00531514 |
| PAM | peptidylglycine alpha-amidating monooxygenase | -0.0053127 |
| COL1A1 | collagen, type I, alpha 1 | -0.00530171 |
| VLDLR | very low density lipoprotein receptor | -0.0052834 |
| LXN | latexin | -0.00527361 |
| PDE8B | phosphodiesterase 8B | -0.00526587 |
| PROS1 | protein S (alpha) | -0.00526556 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.00526048 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.00525389 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.00525114 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.00524368 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00523621 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 | -0.00520951 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00520905 |
| HIP1R | huntingtin interacting protein 1 related | -0.00519659 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00518685 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00518138 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.0051744 |
| MYO5C | myosin VC | -0.00516782 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00516671 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0051595 |
| SPATA20 | spermatogenesis associated 20 | -0.00513922 |
| CRHBP | corticotropin releasing hormone binding protein | -0.00511953 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0051111 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0051021 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | -0.00510137 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -0.00507788 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0050778 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0050766 |
| SMAD7 | SMAD family member 7 | -0.00507618 |
| STK26 | serine/threonine protein kinase 26 | -0.00506895 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00506875 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.00505531 |
| INSM1 | insulinoma-associated 1 | -0.00505407 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0050532 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0050529 |
| MED13 | mediator complex subunit 13 | -0.00504661 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0050264 |
| LIPG | lipase, endothelial | -0.00502425 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.00502277 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.00501758 |
| MAOA | monoamine oxidase A | -0.00499988 |
| RABAC1 | Rab acceptor 1 (prenylated) | -0.00499107 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 | -0.00497182 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00496127 |
| HIRA | histone cell cycle regulator | -0.00495717 |
| MCOLN1 | mucolipin 1 | -0.00495559 |
| SUN2 | Sad1 and UNC84 domain containing 2 | -0.00495103 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0049468 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | -0.00493872 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -0.00493352 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | -0.00493262 |
| MFAP5 | microfibrillar associated protein 5 | -0.00493096 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00492961 |
| RAP1GAP | RAP1 GTPase activating protein | -0.00492533 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0049178 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | -0.00490475 |
| PLCL2 | phospholipase C-like 2 | -0.00489317 |
| ADCY9 | adenylate cyclase 9 | -0.00488846 |
| RRBP1 | ribosome binding protein 1 | -0.00488025 |
| MLXIP | MLX interacting protein | -0.0048796 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.00483968 |
| PTBP1 | polypyrimidine tract binding protein 1 | -0.00482987 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00482976 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00482934 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -0.00482927 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | -0.00480868 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.00480116 |
| SMTN | smoothelin | -0.00478833 |
| FAM46C | family with sequence similarity 46, member C | -0.00478686 |
| FAM50A | family with sequence similarity 50, member A | -0.00478109 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00478106 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00477692 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.00476832 |
| EIF6 | eukaryotic translation initiation factor 6 | -0.00476238 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | -0.00476207 |
| GSE1 | Gse1 coiled-coil protein | -0.00476064 |
| RASA4 | RAS p21 protein activator 4 | -0.00475165 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00474538 |
| GATA2 | GATA binding protein 2 | -0.0047398 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00473882 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00473699 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.00473688 |
| ASS1 | argininosuccinate synthase 1 | -0.00473259 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00472713 |
