SIRT1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description sirtuin 1|This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008] (NCBI Entrez Gene Database, 23411)
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Genes

403 genes differentially expressed following the SIRT1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
POU2F3 POU class 2 homeobox 3 4.03908
CERKL ceramide kinase-like 4.03908
AQP7 aquaporin 7 4.03908
C8ORF48 chromosome 8 open reading frame 48 4.03908
MSANTD1 Myb/SANT-like DNA-binding domain containing 1 4.03908
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 4.03908
BPIFC BPI fold containing family C 4.03908
PSORS1C2 psoriasis susceptibility 1 candidate 2 4.03908
ZNF575 zinc finger protein 575 4.03908
A1CF APOBEC1 complementation factor 4.03908
SMTNL1 smoothelin-like 1 4.03908
SFRP5 secreted frizzled-related protein 5 4.03908
CEP295NL CEP295 N-terminal like 4.03908
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 4.03908
C1QL2 complement component 1, q subcomponent-like 2 4.03908
GCSAML germinal center-associated, signaling and motility-like 4.03908
PPP1R3D protein phosphatase 1, regulatory subunit 3D 4.03908
MEIKIN meiotic kinetochore factor 4.03908
C17ORF113 chromosome 17 open reading frame 113 4.03908
CD22 CD22 molecule 4.03908
CLDN9 claudin 9 4.03908
GPR78 G protein-coupled receptor 78 4.03908
CATSPERZ catsper channel auxiliary subunit zeta 4.03908
OR4N2 olfactory receptor, family 4, subfamily N, member 2 4.03908
ZC2HC1B zinc finger, C2HC-type containing 1B 4.03908
SLC25A34 solute carrier family 25, member 34 4.03908
HLX H2.0-like homeobox 4.03908
FER1L6 fer-1-like family member 6 4.03908
KCTD19 potassium channel tetramerization domain containing 19 4.00254
CNTNAP4 contactin associated protein-like 4 3.90128
OR2A25 olfactory receptor, family 2, subfamily A, member 25 3.90128
TXLNB taxilin beta 3.90128
ELAVL4 ELAV like neuron-specific RNA binding protein 4 3.90128
PLIN4 perilipin 4 3.90128
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 3.90128
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 3.90128
SLC46A2 solute carrier family 46, member 2 3.90128
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 3.90128
COL20A1 collagen, type XX, alpha 1 3.90128
NPPB natriuretic peptide B 3.90128
GPR52 G protein-coupled receptor 52 3.90128
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 3.90128
TMEM176A transmembrane protein 176A 3.90128
IL5RA interleukin 5 receptor, alpha 3.90128
TMEM191B transmembrane protein 191B 3.90128
GDNF glial cell derived neurotrophic factor 3.90128
CX3CR1 chemokine (C-X3-C motif) receptor 1 3.90128
C8ORF74 chromosome 8 open reading frame 74 3.90128
DLL4 delta-like 4 (Drosophila) 3.90128
RIMBP3C RIMS binding protein 3C 3.90128
LONRF3 LON peptidase N-terminal domain and ring finger 3 3.90128
IL2RA interleukin 2 receptor, alpha 3.90128
GALR3 galanin receptor 3 3.90128
THSD1 thrombospondin, type I, domain containing 1 3.90128
TTLL8 tubulin tyrosine ligase-like family member 8 3.90128
MOGAT2 monoacylglycerol O-acyltransferase 2 3.90128
PRODH proline dehydrogenase (oxidase) 1 3.90128
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 3.90128
ARHGAP36 Rho GTPase activating protein 36 3.90128
SLC10A5 solute carrier family 10, member 5 3.90128
ASB14 ankyrin repeat and SOCS box containing 14 3.90128
DIRAS3 DIRAS family, GTP-binding RAS-like 3 3.90128
NUGGC nuclear GTPase, germinal center associated 3.90128
ANKRD34A ankyrin repeat domain 34A 3.90128
OTUD6A OTU deubiquitinase 6A 3.90128
THRSP thyroid hormone responsive 3.90128
SP6 Sp6 transcription factor 3.90128
SPMIP9 sperm microtubule inner protein 9 3.90128
SPATS1 spermatogenesis associated, serine-rich 1 3.90128
CES4A carboxylesterase 4A 3.90128
YPEL4 yippee-like 4 (Drosophila) 3.90128
ROPN1B rhophilin associated tail protein 1B 3.90128
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 3.90128
SPI1 Spi-1 proto-oncogene 3.90128
DUSP8 dual specificity phosphatase 8 3.90128
FRG2C FSHD region gene 2 family, member C 3.90128
MLN motilin 3.90128
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H 3.90128
TMPRSS6 transmembrane protease, serine 6 3.90128
ERVW-1 endogenous retrovirus group W, member 1 3.90128
SLURP2 secreted LY6/PLAUR domain containing 2 3.90128
PRR20G proline rich 20G 3.90128
WASH8P WAS protein family homolog 8, pseudogene 3.90128
LINC02268 long intergenic non-protein coding RNA 2268 3.90128
ANKRD42-DT ANKRD42 divergent transcript 3.90128
ZNF593OS ZNF593 opposite strand 3.90128
TUBB8B tubulin beta 8B 3.90128
H2BW1 H2B.W histone 1 3.90128
DEFB131B defensin beta 131B 3.90128
CABCOCO1 ciliary associated calcium binding coiled-coil 1 3.90128
CALHM5 calcium homeostasis modulator family member 5 3.90128
RTL9 retrotransposon Gag like 9 3.90128
IQCF1 IQ motif containing F1 3.90128
PROZ protein Z, vitamin K-dependent plasma glycoprotein 3.90128
NPIPB9 nuclear pore complex interacting protein family, member B9 3.90128
TMEM235 transmembrane protein 235 3.90128
UROC1 urocanate hydratase 1 3.90128
PTP4A1 protein tyrosine phosphatase type IVA, member 1 3.90128
OR9H1 olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene) 3.90128
CD48 CD48 molecule 3.90128
MAG myelin associated glycoprotein 3.90128
TRIM60 tripartite motif containing 60 3.90128
CLDN2 claudin 2 3.90128
NKX2-2 NK2 homeobox 2 3.90128
OR5H2 olfactory receptor, family 5, subfamily H, member 2 3.90128
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 3.90128
HAPLN2 hyaluronan and proteoglycan link protein 2 3.90128
MYPN myopalladin 3.90128
LY6K lymphocyte antigen 6 complex, locus K 3.90128
MAGIX MAGI family member, X-linked 3.90128
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1 3.90128
GATA6 GATA binding protein 6 3.90128
FRK fyn-related Src family tyrosine kinase 3.90128
RBM44 RNA binding motif protein 44 3.90128
CELA2A chymotrypsin-like elastase family, member 2A 3.90128
RASAL3 RAS protein activator like 3 3.90128
LEF1 lymphoid enhancer-binding factor 1 3.90128
TLR1 toll-like receptor 1 3.90128
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 3.90128
OR4D2 olfactory receptor, family 4, subfamily D, member 2 3.90128
CT55 cancer/testis antigen 55 3.90128
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 3.90128
AQP8 aquaporin 8 3.90128
FADS6 fatty acid desaturase 6 3.90128
DEFB107B defensin, beta 107B 3.90128
PRR33 proline rich 33 3.90128
CLRN1 clarin 1 3.90128
HHIPL2 HHIP-like 2 3.90128
STMND1 stathmin domain containing 1 3.90128
OR56B1 olfactory receptor, family 56, subfamily B, member 1 3.90128
OPTC opticin 3.90128
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 3.90128
TTC24 tetratricopeptide repeat domain 24 3.90128
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 3.90128
PSORS1C1 psoriasis susceptibility 1 candidate 1 3.90128
PFN4 profilin family, member 4 3.90128
SPEF1 sperm flagellar 1 3.90128
FCN3 ficolin (collagen/fibrinogen domain containing) 3 3.90128
ZMYND10 zinc finger, MYND-type containing 10 3.90128
HSF4 heat shock transcription factor 4 3.90128
DAW1 dynein assembly factor with WDR repeat domains 1 3.90128
CTSS cathepsin S 3.90128
CD27 CD27 molecule 3.90128
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 3.90128
PRND prion protein 2 (dublet) 3.90128
MOS v-mos Moloney murine sarcoma viral oncogene homolog 3.90128
DBX2 developing brain homeobox 2 3.90128
TBC1D28 TBC1 domain family, member 28 3.90128
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 3.90128
LYZ lysozyme 3.90128
KCNK3 potassium channel, two pore domain subfamily K, member 3 3.90128
SNTN sentan, cilia apical structure protein 3.90128
ANKRD61 ankyrin repeat domain 61 3.90128
IL10RA interleukin 10 receptor, alpha 3.90128
RANBP3L RAN binding protein 3-like 3.90128
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 3.90128
CD33 CD33 molecule 3.90128
NFE2 nuclear factor, erythroid 2 3.90128
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 3.90128
UPK1B uroplakin 1B 3.90128
C2CD4B C2 calcium-dependent domain containing 4B 3.90128
AMIGO3 adhesion molecule with Ig-like domain 3 3.90128
URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase 3.90128
HRCT1 histidine rich carboxyl terminus 1 3.90128
RORC RAR-related orphan receptor C 3.90128
BTBD16 BTB (POZ) domain containing 16 3.90128
LRRK2 leucine-rich repeat kinase 2 3.90128
GSDMA gasdermin A 3.90128
IRX3 iroquois homeobox 3 3.90128
ASCL3 achaete-scute family bHLH transcription factor 3 3.90128
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 3.90128
ST18 suppression of tumorigenicity 18, zinc finger 3.90128
ADAM8 ADAM metallopeptidase domain 8 3.90128
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 3.90128
TGM4 transglutaminase 4 3.90128
CALHM1 calcium homeostasis modulator 1 3.90128
TNP2 transition protein 2 (during histone to protamine replacement) 3.90128
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 3.90128
IL22RA1 interleukin 22 receptor, alpha 1 3.90128
GPRC5A G protein-coupled receptor, class C, group 5, member A 3.90128
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 3.90128
AHSG alpha-2-HS-glycoprotein 3.90128
AZU1 azurocidin 1 3.90128
NGB neuroglobin 3.90128
TEX26 testis expressed 26 3.90128
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 3.71973
ZNF837 zinc finger protein 837 3.71973
TEX46 testis expressed 46 3.71973
SPATA12 spermatogenesis associated 12 3.71973
PRRT1 proline-rich transmembrane protein 1 3.71973
PYCR1 pyrroline-5-carboxylate reductase 1 3.69322
NPIPA2 nuclear pore complex interacting protein family, member A2 3.49948
ACAD9 acyl-CoA dehydrogenase family, member 9 3.43907
CDR2 cerebellar degeneration-related protein 2, 62kDa 3.1066
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 3.02181
DCTN4 dynactin 4 (p62) 2.98671
CCNB1 cyclin B1 2.96467
LHFPL5 lipoma HMGIC fusion partner-like 5 2.93103
TRAM1 translocation associated membrane protein 1 2.83823
EIF5A eukaryotic translation initiation factor 5A 2.75493
CDK1 cyclin-dependent kinase 1 2.7391
DBF4B DBF4 zinc finger B 2.70218
ANAPC7 anaphase promoting complex subunit 7 2.67521
MX1 MX dynamin-like GTPase 1 2.63898
UBE2R2 ubiquitin-conjugating enzyme E2R 2 2.63649
DESI2 desumoylating isopeptidase 2 2.61748
MRPL9 mitochondrial ribosomal protein L9 2.59061
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4 2.57768
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) 2.56941
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 2.56718
ZNF155 zinc finger protein 155 2.55332
PAQR9 progestin and adipoQ receptor family member IX 2.55332
ZNF471 zinc finger protein 471 2.55332
CD1D CD1d molecule 2.55332
ANXA8 annexin A8 2.55332
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 2.53233
DIPK1B divergent protein kinase domain 1B 2.52868
DRG1 developmentally regulated GTP binding protein 1 2.52836
IFNGR1 interferon gamma receptor 1 2.52281
ARL2 ADP-ribosylation factor-like 2 2.52023
MTG2 mitochondrial ribosome-associated GTPase 2 2.45633
MYDGF myeloid-derived growth factor 2.44272
DRC8 dynein regulatory complex subunit 8 2.43855
FBXL15 F-box and leucine-rich repeat protein 15 2.43531
PCDHA12 protocadherin alpha 12 2.41469
ZNF202 zinc finger protein 202 2.4122
CALR3 calreticulin 3 2.41214
CCDC92B coiled-coil domain containing 92B 2.38973
HEATR9 HEAT repeat containing 9 2.38973
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 2.35628
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 2.35591
CHKA choline kinase alpha 2.34408
TMEM216 transmembrane protein 216 2.34188
MLXIPL MLX interacting protein-like 2.32873
HMOX2 heme oxygenase 2 2.32441
EXD3 exonuclease 3'-5' domain containing 3 2.32377
SFN stratifin 2.30931
TBRG4 transforming growth factor beta regulator 4 2.30575
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 2.30283
ZFYVE19 zinc finger, FYVE domain containing 19 2.29351
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) 2.2918
CCDC117 coiled-coil domain containing 117 2.28251
CD163L1 CD163 molecule-like 1 2.28251
ZFR2 zinc finger RNA binding protein 2 2.24389
PDCD11 programmed cell death 11 2.23957
RP1 retinitis pigmentosa 1 (autosomal dominant) 2.23041
JOSD2 Josephin domain containing 2 2.23041
MEPCE methylphosphate capping enzyme 2.22438
SDC2 syndecan 2 2.18114
MIEF1 mitochondrial elongation factor 1 2.14524
FXYD5 FXYD domain containing ion transport regulator 5 2.13684
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 2.13074
MAST2 microtubule associated serine/threonine kinase 2 2.11313
SLC44A2 solute carrier family 44 (choline transporter), member 2 2.1123
BACE2 beta-site APP-cleaving enzyme 2 2.11109
GLS2 glutaminase 2 (liver, mitochondrial) 2.09914
MPDZ multiple PDZ domain protein 2.08072
AHCY adenosylhomocysteinase 2.08072
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain 2.07764
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa 2.06636
BRD3OS BRD3 opposite strand 2.04861
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 2.0418
TCAF1 TRPM8 channel-associated factor 1 2.03279
UBA1 ubiquitin-like modifier activating enzyme 1 2.00108
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 2.00108

decreased expression

Symbol Name Standardized Value
STAG3 stromal antigen 3 -4.03908
FHIP2B FHF complex subunit HOOK interacting protein 2B -4.03908
LYSMD1 LysM, putative peptidoglycan-binding, domain containing 1 -4.03908
FAM209B family with sequence similarity 209, member B -4.03908
HAP1 huntingtin-associated protein 1 -4.03908
CD79B CD79b molecule, immunoglobulin-associated beta -4.03908
MEIS1 Meis homeobox 1 -4.03908
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 -4.03908
ODAD1 outer dynein arm docking complex subunit 1 -3.90128
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -3.90128
RPL3L ribosomal protein L3-like -3.90128
CD101 CD101 molecule -3.90128
MGAM maltase-glucoamylase -3.90128
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -3.90128
CRYGB crystallin, gamma B -3.90128
NR4A2 nuclear receptor subfamily 4, group A, member 2 -3.90128
CNTN6 contactin 6 -3.90128
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -3.90128
CD34 CD34 molecule -3.90128
CNTFR ciliary neurotrophic factor receptor -3.90128
OR52A1 olfactory receptor, family 52, subfamily A, member 1 -3.90128
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 -3.90128
FAM161B family with sequence similarity 161, member B -3.90128
LOC122526780 uncharacterized LOC122526780 -3.90128
PATL2 protein associated with topoisomerase II homolog 2 (yeast) -3.90128
CFAP157 cilia and flagella associated protein 157 -3.90128
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma -3.90128
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled -3.90128
SYT1 synaptotagmin I -3.90128
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -3.90128
KLK4 kallikrein-related peptidase 4 -3.90128
TEKT5 tektin 5 -3.90128
NIBAN3 niban apoptosis regulator 3 -3.90128
DRD3 dopamine receptor D3 -3.90128
IRGM immunity-related GTPase family, M -3.90128
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -3.71973
SZT2 seizure threshold 2 homolog (mouse) -3.71399
GSAP gamma-secretase activating protein -3.59334
NPIPB5 nuclear pore complex interacting protein family, member B5 -3.59025
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 -3.52193
SIRT1 sirtuin 1 -3.43907
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -3.34332
PYGM phosphorylase, glycogen, muscle -3.31833
SLC22A31 solute carrier family 22, member 31 -3.31833
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 -3.31833
GYPE glycophorin E (MNS blood group) -3.31833
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 -3.31833
MT1E metallothionein 1E -3.20083
CMYA5 cardiomyopathy associated 5 -3.19509
IPO7 importin 7 -3.14649
EXOC2 exocyst complex component 2 -3.1303
ADCY7 adenylate cyclase 7 -3.13024
KIAA0586 KIAA0586 -3.00287
STAMBP STAM binding protein -3.00287
AKT3 v-akt murine thymoma viral oncogene homolog 3 -3.00287
GRID2 glutamate receptor, ionotropic, delta 2 -2.99739
MBOAT1 membrane bound O-acyltransferase domain containing 1 -2.98671
L1TD1 LINE-1 type transposase domain containing 1 -2.98309
EPHA6 EPH receptor A6 -2.93314
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 -2.89577
CRYAB crystallin, alpha B -2.88901
PTGES3L prostaglandin E synthase 3 (cytosolic)-like -2.88901
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -2.8458
MINDY2 MINDY lysine 48 deubiquitinase 2 -2.81242
TMEM132B transmembrane protein 132B -2.80181
PBX3 pre-B-cell leukemia homeobox 3 -2.79942
FAT3 FAT atypical cadherin 3 -2.79013
MYOM1 myomesin 1 -2.75653
DPPA4 developmental pluripotency associated 4 -2.67934
OTUD7A OTU deubiquitinase 7A -2.67521
TMEM175 transmembrane protein 175 -2.6678
FAM89A family with sequence similarity 89, member A -2.6678
RARB retinoic acid receptor, beta -2.6678
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 -2.6588
FAM193B family with sequence similarity 193, member B -2.65817
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -2.64267
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -2.62379
G0S2 G0/G1 switch 2 -2.588
CUBN cubilin (intrinsic factor-cobalamin receptor) -2.588
WDSUB1 WD repeat, sterile alpha motif and U-box domain containing 1 -2.58189
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -2.56575
NRBF2 nuclear receptor binding factor 2 -2.55332
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -2.55332
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) -2.55332
POC5 POC5 centriolar protein -2.55332
CASP6 caspase 6, apoptosis-related cysteine peptidase -2.55234
ADGRL3 adhesion G protein-coupled receptor L3 -2.53657
CFAP90 cilia and flagella associated protein 90 -2.53468
GNA12 guanine nucleotide binding protein (G protein) alpha 12 -2.52868
HAPLN1 hyaluronan and proteoglycan link protein 1 -2.49874
RNF220 ring finger protein 220 -2.49601
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B -2.47752
BEST2 bestrophin 2 -2.47752
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -2.44643
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -2.44345
NALF1 NALCN channel auxiliary factor 1 -2.42726
LSM1 LSM1, U6 small nuclear RNA associated -2.41707
NANOG Nanog homeobox -2.41214
LENG8 leukocyte receptor cluster (LRC) member 8 -2.38973
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -2.38973
NRG3 neuregulin 3 -2.37598
DDT D-dopachrome tautomerase -2.36774
ADHFE1 alcohol dehydrogenase, iron containing, 1 -2.3539
TRIM2 tripartite motif containing 2 -2.35107
USP54 ubiquitin specific peptidase 54 -2.33816
VCAN versican -2.32034
CHRM2 cholinergic receptor, muscarinic 2 -2.28783
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) -2.28018
AIF1 allograft inflammatory factor 1 -2.25761
RBMS2 RNA binding motif, single stranded interacting protein 2 -2.25681
MXRA7 matrix-remodelling associated 7 -2.24389
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 -2.19802
ELN elastin -2.19356
MCM3 minichromosome maintenance complex component 3 -2.17916
DTNA dystrobrevin, alpha -2.17476
WDR12 WD repeat domain 12 -2.13684
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -2.11998
TNRC18 trinucleotide repeat containing 18 -2.11399
ZNF688 zinc finger protein 688 -2.11399
NGF nerve growth factor (beta polypeptide) -2.11399
IQGAP2 IQ motif containing GTPase activating protein 2 -2.11313
HSDL2 hydroxysteroid dehydrogenase like 2 -2.10753
GALE UDP-galactose-4-epimerase -2.10667
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -2.10647
COL5A1 collagen, type V, alpha 1 -2.10311
PTBP2 polypyrimidine tract binding protein 2 -2.09451
IL20RA interleukin 20 receptor, alpha -2.07764
MINDY4 MINDY lysine 48 deubiquitinase 4 -2.06636
NUBPL nucleotide binding protein-like -2.06636
AGMO alkylglycerol monooxygenase -2.04861
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae) -2.04318
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14 -2.04318
CLEC2D C-type lectin domain family 2, member D -2.039
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -2.01769
TMEM70 transmembrane protein 70 -2.01061
MTRFR mitochondrial translation release factor in rescue -2.01061
BAZ2A bromodomain adjacent to zinc finger domain, 2A -2.01061
TLCD4 TLC domain containing 4 -2.00251