| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | sirtuin 1|This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008] (NCBI Entrez Gene Database, 23411) |
| External Link | https://ncbi.nlm.nih.gov/gene/23411 |
| Similar Terms | |
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499 genes differentially expressed following the SIRT1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.0130744 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0115779 |
| CCNA2 | cyclin A2 | 0.0113649 |
| S100P | S100 calcium binding protein P | 0.0113644 |
| GATA6 | GATA binding protein 6 | 0.0109657 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.010919 |
| TAGLN | transgelin | 0.0106317 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0100157 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00997269 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00940093 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00933935 |
| AMOTL2 | angiomotin like 2 | 0.00925267 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00913445 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.009118 |
| DUSP5 | dual specificity phosphatase 5 | 0.00908118 |
| CTH | cystathionine gamma-lyase | 0.00903836 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0088552 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 0.00864303 |
| AEBP1 | AE binding protein 1 | 0.0086023 |
| RRBP1 | ribosome binding protein 1 | 0.00850375 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00841703 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00835777 |
| G0S2 | G0/G1 switch 2 | 0.00834149 |
| C7 | complement component 7 | 0.00827364 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00816483 |
| NEFH | neurofilament, heavy polypeptide | 0.00806653 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.00805183 |
| CDC20 | cell division cycle 20 | 0.00802596 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00785777 |
| NAV2 | neuron navigator 2 | 0.00777055 |
| IRS2 | insulin receptor substrate 2 | 0.00776675 |
| S100A11 | S100 calcium binding protein A11 | 0.00772048 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.00764505 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 0.00757998 |
| KRT7 | keratin 7, type II | 0.00756518 |
| CRYAB | crystallin, alpha B | 0.0075165 |
| CCN2 | cellular communication network factor 2 | 0.00750904 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00750887 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00749159 |
| CNTN1 | contactin 1 | 0.00742309 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00741632 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00739403 |
| AOC1 | amine oxidase, copper containing 1 | 0.00737966 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00734839 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.00730881 |
| IRS1 | insulin receptor substrate 1 | 0.00730058 |
| NOTCH2NL | notch 2 N-terminal like | 0.0072937 |
| GPX3 | glutathione peroxidase 3 | 0.00717691 |
| PROCR | protein C receptor, endothelial | 0.00715095 |
| TYMS | thymidylate synthetase | 0.00708003 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.00707578 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00700914 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00699535 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00698987 |
| THBS1 | thrombospondin 1 | 0.00694216 |
| TMEM176B | transmembrane protein 176B | 0.0069175 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.00691382 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.00690752 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.00689868 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00689118 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00687535 |
| FBN2 | fibrillin 2 | 0.00687132 |
| SCPEP1 | serine carboxypeptidase 1 | 0.00685638 |
| TNS3 | tensin 3 | 0.00685473 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00681746 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00680507 |
| LIPG | lipase, endothelial | 0.00677634 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) | 0.00676096 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.00666219 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00665604 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | 0.00661559 |
| COL16A1 | collagen, type XVI, alpha 1 | 0.00660376 |
| GALC | galactosylceramidase | 0.00654173 |
| RGS4 | regulator of G-protein signaling 4 | 0.00653522 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.00647225 |
| RIN2 | Ras and Rab interactor 2 | 0.00646975 |
| PTK2B | protein tyrosine kinase 2 beta | 0.00642162 |
| SMAD7 | SMAD family member 7 | 0.00641741 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00641364 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | 0.00637499 |
| CDK11A | cyclin-dependent kinase 11A | 0.00636931 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00635604 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.00634157 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00631433 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.00631425 |
| RND3 | Rho family GTPase 3 | 0.00630036 |
| TPM1 | tropomyosin 1 (alpha) | 0.00629899 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00627306 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00626952 |
| CST3 | cystatin C | 0.00626671 |
| SAFB2 | scaffold attachment factor B2 | 0.00626547 |
| ZNF160 | zinc finger protein 160 | 0.00624633 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.00623643 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00622621 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.00621636 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00621452 |
| CD320 | CD320 molecule | 0.00620777 |
| MT1H | metallothionein 1H | 0.00620754 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00616718 |
| VEGFA | vascular endothelial growth factor A | 0.00616468 |
| COL9A2 | collagen, type IX, alpha 2 | 0.00616142 |
| AXL | AXL receptor tyrosine kinase | 0.00615538 |
| MLPH | melanophilin | 0.00613829 |
| HK2 | hexokinase 2 | 0.00612817 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.00610617 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.00607787 |
| SLTM | SAFB-like, transcription modulator | 0.00607487 |
| FBXW12 | F-box and WD repeat domain containing 12 | 0.00606222 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00604584 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.00602321 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.00598901 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00597811 |
| CYBB | cytochrome b-245, beta polypeptide | 0.00597564 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00596683 |
| DMXL2 | Dmx-like 2 | 0.00596557 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00592152 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00589851 |
| THBS4 | thrombospondin 4 | 0.00588319 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 | 0.00587829 |
| RET | ret proto-oncogene | 0.00587688 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00587672 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00587526 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00585745 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00585691 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | 0.00578769 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00578643 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 0.00578256 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00577603 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.00575937 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00575522 |
| CTSD | cathepsin D | 0.00574609 |
| RAB8A | RAB8A, member RAS oncogene family | 0.00573676 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.00568178 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.00567488 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00566766 |
| SPATA20 | spermatogenesis associated 20 | 0.00565782 |
| S100A4 | S100 calcium binding protein A4 | 0.00565187 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00564889 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.00564234 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00563998 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0056164 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00560963 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00560842 |
| YTHDC1 | YTH domain containing 1 | 0.00560567 |
| C2CD5 | C2 calcium-dependent domain containing 5 | 0.00560065 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | 0.00558962 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00558875 |
| KRT18 | keratin 18, type I | 0.00558167 |
| ACTC1 | actin, alpha, cardiac muscle 1 | 0.00557623 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00556459 |
| MFGE8 | milk fat globule-EGF factor 8 protein | 0.00554214 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0055414 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00552809 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00552138 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00551227 |
| FBLN1 | fibulin 1 | 0.00551187 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00548542 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00548115 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00547619 |
| PLCB4 | phospholipase C, beta 4 | 0.00547118 |
| SQSTM1 | sequestosome 1 | 0.00546958 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00546418 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.00546384 |
| TYMP | thymidine phosphorylase | 0.00546164 |
| LAMB1 | laminin, beta 1 | 0.00545816 |
| CD81 | CD81 molecule | 0.0054535 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00544675 |
| ANK2 | ankyrin 2, neuronal | 0.00542801 |
| STK10 | serine/threonine kinase 10 | 0.00542149 |
| RGS16 | regulator of G-protein signaling 16 | 0.00541398 |
| AGR2 | anterior gradient 2 | 0.005413 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00540928 |
| JAG1 | jagged 1 | 0.00540006 |
| FSTL1 | follistatin-like 1 | 0.00539915 |
| LRRC8D | leucine rich repeat containing 8 family, member D | 0.00539574 |
| TFF2 | trefoil factor 2 | 0.00539428 |
| EML3 | echinoderm microtubule associated protein like 3 | 0.00539369 |
| PRRC2C | proline-rich coiled-coil 2C | 0.00538486 |
| CALCA | calcitonin-related polypeptide alpha | 0.00537986 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.00536907 |
| ADIRF | adipogenesis regulatory factor | 0.00536696 |
| LAMP1 | lysosomal-associated membrane protein 1 | 0.00536542 |
| PCP4 | Purkinje cell protein 4 | 0.00536482 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.00535863 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00534949 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.00534842 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.00533852 |
| ANXA5 | annexin A5 | 0.00533784 |
| STK26 | serine/threonine protein kinase 26 | 0.0053288 |
| NOTCH2 | notch 2 | 0.00531917 |
| GPX2 | glutathione peroxidase 2 | 0.00531302 |
| BMP2 | bone morphogenetic protein 2 | 0.00529991 |
| APOC1 | apolipoprotein C-I | 0.00527082 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0052664 |
| EPS8L2 | EPS8-like 2 | 0.00525687 |
| TPD52L2 | tumor protein D52-like 2 | 0.00525299 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00525297 |
| RBM26 | RNA binding motif protein 26 | 0.0052451 |
| MT1E | metallothionein 1E | 0.00524216 |
| KIF1A | kinesin family member 1A | 0.00523566 |
| TNNC1 | troponin C type 1 (slow) | 0.00523157 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.00522337 |
| ACTN4 | actinin, alpha 4 | 0.00522277 |
| DUSP1 | dual specificity phosphatase 1 | 0.0052219 |
| MAGEA3 | melanoma antigen family A3 | 0.00521201 |
| XIC | X chromosome inactivation center | 0.00520982 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | 0.0052096 |
| AOX1 | aldehyde oxidase 1 | 0.00520501 |
| MTMR11 | myotubularin related protein 11 | 0.00520258 |
| CTSZ | cathepsin Z | 0.00520225 |
| STK38 | serine/threonine kinase 38 | 0.00519194 |
| PRR11 | proline rich 11 | 0.00519098 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0051879 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00516733 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.00516426 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | 0.00515438 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.00514354 |
| FZD2 | frizzled class receptor 2 | 0.00512591 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00511524 |
| SIX1 | SIX homeobox 1 | 0.00511512 |
| PLIN1 | perilipin 1 | 0.00511139 |
| CA3 | carbonic anhydrase III | 0.00509226 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00508948 |
| TUBB6 | tubulin, beta 6 class V | 0.0050789 |
| TXLNA | taxilin alpha | 0.00507696 |
| GGT1 | gamma-glutamyltransferase 1 | 0.0050686 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | 0.00506725 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 0.00506316 |
| NCOA2 | nuclear receptor coactivator 2 | 0.00506312 |
| EPHA2 | EPH receptor A2 | 0.00504993 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00504914 |
| MINK1 | misshapen-like kinase 1 | 0.00504689 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00504681 |
| PLA1A | phospholipase A1 member A | 0.00503726 |
| MMP9 | matrix metallopeptidase 9 | 0.00503478 |
| CCNL2 | cyclin L2 | 0.00502888 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.00502128 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.00500352 |
| MYOF | myoferlin | 0.00499272 |
| ADAMTSL3 | ADAMTS-like 3 | 0.00497838 |
| CKM | creatine kinase, muscle | 0.00497319 |
| RBPMS | RNA binding protein with multiple splicing | 0.00496815 |
| RBM25 | RNA binding motif protein 25 | 0.00496708 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00496232 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00494546 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00493897 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00493685 |
| NAV3 | neuron navigator 3 | 0.0049247 |
| ARL14 | ADP-ribosylation factor-like 14 | 0.00491172 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RGCC | regulator of cell cycle | -0.0142566 |
| TUBB2A | tubulin, beta 2A class IIa | -0.0135296 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0121404 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0115656 |
| DNM1L | dynamin 1-like | -0.0106439 |
| DEFB1 | defensin, beta 1 | -0.0101649 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.0101164 |
| DAXX | death-domain associated protein | -0.0100386 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00996145 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00982678 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00965349 |
| CHN1 | chimerin 1 | -0.00963135 |
| ZNF395 | zinc finger protein 395 | -0.00958617 |
| CYBRD1 | cytochrome b reductase 1 | -0.00953262 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00945098 |
| S100A7 | S100 calcium binding protein A7 | -0.00943526 |
| GATA3 | GATA binding protein 3 | -0.00937512 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00933662 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00929472 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00917372 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.00889791 |
| RPS5 | ribosomal protein S5 | -0.00888768 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00882869 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00870539 |
| LTF | lactotransferrin | -0.00858345 |
| KRT5 | keratin 5, type II | -0.00853632 |
| SDC2 | syndecan 2 | -0.00852101 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00847025 |
| CLDN8 | claudin 8 | -0.00843897 |
| NRN1 | neuritin 1 | -0.00840768 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | -0.00823054 |
| NGRN | neugrin, neurite outgrowth associated | -0.00812409 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.008108 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00802989 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00776834 |
| ASRGL1 | asparaginase like 1 | -0.00775013 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.00774759 |
| MIPEP | mitochondrial intermediate peptidase | -0.00765517 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.0076001 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00759294 |
| SOSTDC1 | sclerostin domain containing 1 | -0.0075803 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00757961 |
| SELL | selectin L | -0.00755929 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00755317 |
| GPC3 | glypican 3 | -0.00751757 |
| KYNU | kynureninase | -0.00749864 |
| HAT1 | histone acetyltransferase 1 | -0.00749409 |
| DAZAP2 | DAZ associated protein 2 | -0.00748456 |
| FOXG1 | forkhead box G1 | -0.00745578 |
| PIP | prolactin-induced protein | -0.00738077 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00737791 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00736152 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00735563 |
| MSMO1 | methylsterol monooxygenase 1 | -0.00733739 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00730874 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0072941 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.00722947 |
| CEP68 | centrosomal protein 68kDa | -0.00716495 |
| CLCA2 | chloride channel accessory 2 | -0.00713423 |
| CD99 | CD99 molecule | -0.00712296 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0071103 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00710003 |
| GPM6B | glycoprotein M6B | -0.00704091 |
| GOLT1B | golgi transport 1B | -0.00703924 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00701318 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00697329 |
| CHI3L2 | chitinase 3-like 2 | -0.00690807 |
| MAL | mal, T-cell differentiation protein | -0.00690448 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00686789 |
| TYRP1 | tyrosinase-related protein 1 | -0.00684796 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00684292 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.00681942 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00673912 |
| GLUD2 | glutamate dehydrogenase 2 | -0.00670888 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -0.00668268 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.00667816 |
| XPO7 | exportin 7 | -0.00663866 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.00662307 |
| VSNL1 | visinin-like 1 | -0.00661642 |
| FKBP5 | FK506 binding protein 5 | -0.00660502 |
| LAGE3 | L antigen family, member 3 | -0.00660473 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00659436 |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein I | -0.00656353 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00655929 |
| FANCA | Fanconi anemia, complementation group A | -0.00646639 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.00646515 |
| EFNA1 | ephrin-A1 | -0.00644754 |
| STC1 | stanniocalcin 1 | -0.00643921 |
| IQCG | IQ motif containing G | -0.00643643 |
| FABP7 | fatty acid binding protein 7, brain | -0.00641948 |
| CSTA | cystatin A (stefin A) | -0.00636093 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.0063582 |
| SIRT3 | sirtuin 3 | -0.00634558 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00633459 |
| AK4 | adenylate kinase 4 | -0.00630432 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | -0.00628929 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00624568 |
| ESD | esterase D | -0.00622512 |
| BMERB1 | bMERB domain containing 1 | -0.00622342 |
| MMD | monocyte to macrophage differentiation-associated | -0.00618964 |
| ERGIC2 | ERGIC and golgi 2 | -0.00618923 |
| FABP1 | fatty acid binding protein 1, liver | -0.00616665 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | -0.00616075 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00615735 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -0.00614175 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00614154 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0061321 |
| MMP3 | matrix metallopeptidase 3 | -0.00612117 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00611 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00610721 |
| AHSG | alpha-2-HS-glycoprotein | -0.00608749 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | -0.00607433 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00605481 |
| CD93 | CD93 molecule | -0.00605395 |
| GLUL | glutamate-ammonia ligase | -0.00604927 |
| S100A14 | S100 calcium binding protein A14 | -0.00604256 |
| STOM | stomatin | -0.00603317 |
| MPZL2 | myelin protein zero-like 2 | -0.00602491 |
| TMEM231 | transmembrane protein 231 | -0.00601247 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00596892 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00595495 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00594332 |
| RNF144A | ring finger protein 144A | -0.00593151 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00592757 |
| ADD3 | adducin 3 (gamma) | -0.00591784 |
| CALCRL | calcitonin receptor-like | -0.00591586 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.00587643 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.00587169 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | -0.00587114 |
| CD52 | CD52 molecule | -0.00586199 |
| IDE | insulin-degrading enzyme | -0.00586139 |
| APOO | apolipoprotein O | -0.00586121 |
| NCOA4 | nuclear receptor coactivator 4 | -0.00584889 |
| DALRD3 | DALR anticodon binding domain containing 3 | -0.00583437 |
| MLF1 | myeloid leukemia factor 1 | -0.00583296 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.00581453 |
| TMEM204 | transmembrane protein 204 | -0.00579262 |
| BID | BH3 interacting domain death agonist | -0.00576363 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00574892 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.00574207 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | -0.00571999 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | -0.00571099 |
| STON1 | stonin 1 | -0.00569206 |
| EXOC5 | exocyst complex component 5 | -0.00566229 |
| APOB | apolipoprotein B | -0.00561437 |
| TCTA | T-cell leukemia translocation altered | -0.00561394 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0056139 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.00561254 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.00558826 |
| TNC | tenascin C | -0.00558619 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00557791 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00557581 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0055702 |
| HCRT | hypocretin (orexin) neuropeptide precursor | -0.00556521 |
| LOR | loricrin | -0.00556068 |
| SET | SET nuclear proto-oncogene | -0.00552725 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.00552408 |
| HIST3H2A | histone cluster 3, H2a | -0.00551646 |
| ERGIC3 | ERGIC and golgi 3 | -0.00551607 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00551587 |
| ACP6 | acid phosphatase 6, lysophosphatidic | -0.00549943 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | -0.00548887 |
| CRIP2 | cysteine-rich protein 2 | -0.00548121 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00547803 |
| ITGA6 | integrin, alpha 6 | -0.00546443 |
| SPRR1B | small proline-rich protein 1B | -0.00546356 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | -0.00542658 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.00539075 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00536876 |
| CLDN10 | claudin 10 | -0.00536729 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00534416 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | -0.00534079 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | -0.0053335 |
| COL1A2 | collagen, type I, alpha 2 | -0.00531723 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00531317 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | -0.00531027 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00530526 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial | -0.00529215 |
| DRG1 | developmentally regulated GTP binding protein 1 | -0.00528742 |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | -0.00525165 |
| IQCK | IQ motif containing K | -0.0052381 |
| DSP | desmoplakin | -0.0052352 |
| PLPBP | pyridoxal phosphate binding protein | -0.00523517 |
| AQP4 | aquaporin 4 | -0.00523296 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00522924 |
| IFT46 | intraflagellar transport 46 | -0.0052257 |
| DCTN4 | dynactin 4 (p62) | -0.00521076 |
| SLC25A12 | solute carrier family 25 (aspartate/glutamate carrier), member 12 | -0.00520907 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.00520884 |
| TMEM45A | transmembrane protein 45A | -0.00519681 |
| CLCA4 | chloride channel accessory 4 | -0.00518781 |
| SLA | Src-like-adaptor | -0.00518298 |
| SSR1 | signal sequence receptor, alpha | -0.00516774 |
| NDUFA8 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa | -0.00515739 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00515077 |
| IL1R1 | interleukin 1 receptor, type I | -0.00514774 |
| IFT52 | intraflagellar transport 52 | -0.00514594 |
| AREG | amphiregulin | -0.00514492 |
| MPHOSPH6 | M-phase phosphoprotein 6 | -0.00514372 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.00513343 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.00510623 |
| CHN2 | chimerin 2 | -0.00509581 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -0.00509477 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00508241 |
| RPL29 | ribosomal protein L29 | -0.00508211 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -0.00508108 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00507382 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | -0.00505678 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00505316 |
| RGS10 | regulator of G-protein signaling 10 | -0.00504861 |
| SAR1B | secretion associated, Ras related GTPase 1B | -0.00504661 |
| UFC1 | ubiquitin-fold modifier conjugating enzyme 1 | -0.00503945 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | -0.00503835 |
| MRPS7 | mitochondrial ribosomal protein S7 | -0.00503139 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.00503093 |
| SHROOM2 | shroom family member 2 | -0.00502368 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | -0.00501795 |
| HPF1 | histone PARylation factor 1 | -0.00499542 |
| CFH | complement factor H | -0.00497993 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.00497377 |
| BSPRY | B-box and SPRY domain containing | -0.00495552 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | -0.00494158 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00489813 |
| NDP | Norrie disease (pseudoglioma) | -0.00489677 |
| HOPX | HOP homeobox | -0.00489298 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00487907 |
| IFNGR1 | interferon gamma receptor 1 | -0.00486254 |
| CD34 | CD34 molecule | -0.00483995 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00483771 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00483047 |
| RPL14 | ribosomal protein L14 | -0.00482068 |
| MAGT1 | magnesium transporter 1 | -0.00481845 |
| ANGPT2 | angiopoietin 2 | -0.00481608 |
| PRKCH | protein kinase C, eta | -0.00481544 |
| TCTN3 | tectonic family member 3 | -0.00481436 |
| ILF2 | interleukin enhancer binding factor 2 | -0.0048068 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0048067 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.00480423 |
| FMO5 | flavin containing monooxygenase 5 | -0.00479854 |
| MRPL40 | mitochondrial ribosomal protein L40 | -0.00479299 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00478736 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00478454 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.00477584 |
| IRF6 | interferon regulatory factor 6 | -0.00477087 |
| S100A2 | S100 calcium binding protein A2 | -0.0047681 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00476414 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | -0.00475617 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00474936 |
| BTG3 | BTG family, member 3 | -0.00473658 |
| STAT5B | signal transducer and activator of transcription 5B | -0.00473584 |
