SIRT2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description sirtuin 2|This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010] (NCBI Entrez Gene Database, 22933)
External Link https://ncbi.nlm.nih.gov/gene/22933
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Genes

500 genes differentially expressed following the SIRT2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.0155247
CXCL8 chemokine (C-X-C motif) ligand 8 0.0152911
ANXA1 annexin A1 0.0136712
IFI27 interferon, alpha-inducible protein 27 0.012488
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0119535
CSTA cystatin A (stefin A) 0.0113455
MAL mal, T-cell differentiation protein 0.0110238
SGCE sarcoglycan, epsilon 0.0107093
S100A9 S100 calcium binding protein A9 0.0101771
RGCC regulator of cell cycle 0.0101253
LCN2 lipocalin 2 0.0101035
G0S2 G0/G1 switch 2 0.0100702
CCND1 cyclin D1 0.010031
S100A2 S100 calcium binding protein A2 0.00996738
CPE carboxypeptidase E 0.00964085
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00947066
TFRC transferrin receptor 0.00943749
ASPH aspartate beta-hydroxylase 0.00929574
HSPA1A heat shock 70kDa protein 1A 0.00928754
DEFB1 defensin, beta 1 0.00918427
ADIRF adipogenesis regulatory factor 0.00915374
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00899946
HSPB8 heat shock 22kDa protein 8 0.00893498
ISG15 ISG15 ubiquitin-like modifier 0.0088776
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00887261
MX1 MX dynamin-like GTPase 1 0.00879728
RNASET2 ribonuclease T2 0.0087624
CRYAB crystallin, alpha B 0.00869595
IFI44 interferon-induced protein 44 0.00866824
CCL20 chemokine (C-C motif) ligand 20 0.00862263
TM4SF1 transmembrane 4 L six family member 1 0.00857002
CFD complement factor D (adipsin) 0.00855681
TRIM22 tripartite motif containing 22 0.0084526
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00835725
TRAM1 translocation associated membrane protein 1 0.00824785
STC1 stanniocalcin 1 0.00808324
SMS spermine synthase 0.00805825
C6ORF48 chromosome 6 open reading frame 48 0.00804312
CAV2 caveolin 2 0.00802094
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00799885
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00796986
EAPP E2F-associated phosphoprotein 0.00796734
HIGD1A HIG1 hypoxia inducible domain family, member 1A 0.00790744
DDIT3 DNA-damage-inducible transcript 3 0.00789693
SLPI secretory leukocyte peptidase inhibitor 0.00782019
HIST1H2AC histone cluster 1, H2ac 0.00771519
IFI44L interferon-induced protein 44-like 0.0076761
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00767172
EVI2A ecotropic viral integration site 2A 0.00755615
RIPK2 receptor-interacting serine-threonine kinase 2 0.00755302
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0075068
SKAP2 src kinase associated phosphoprotein 2 0.00750137
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00746681
IFI6 interferon, alpha-inducible protein 6 0.00744915
CSRP2 cysteine and glycine-rich protein 2 0.00743945
EMP1 epithelial membrane protein 1 0.00742751
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00742605
LYPD1 LY6/PLAUR domain containing 1 0.00734835
HSPA8 heat shock 70kDa protein 8 0.00731852
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.00730632
CEMIP cell migration inducing protein, hyaluronan binding 0.00727024
BTF3P11 basic transcription factor 3 pseudogene 11 0.00722451
CAB39 calcium binding protein 39 0.00722057
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00714198
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00713217
TSPAN8 tetraspanin 8 0.00708767
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00708504
SST somatostatin 0.0070577
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00704076
BAG2 BCL2-associated athanogene 2 0.00703195
C2CD2 C2 calcium-dependent domain containing 2 0.00689884
CXCL2 chemokine (C-X-C motif) ligand 2 0.00686508
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.0068419
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00680853
NIBAN1 niban apoptosis regulator 1 0.00679493
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00679489
DAZAP2 DAZ associated protein 2 0.00676051
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00672982
SNAI2 snail family zinc finger 2 0.00672756
STON1 stonin 1 0.00671841
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.00668547
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00666566
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.00661788
LTBP1 latent transforming growth factor beta binding protein 1 0.00655079
ATF3 activating transcription factor 3 0.00654742
CDC42 cell division cycle 42 0.00653371
GTF2B general transcription factor IIB 0.0065291
HDAC9 histone deacetylase 9 0.00652868
RABGGTB Rab geranylgeranyltransferase, beta subunit 0.0064948
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00649424
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00641779
WDR61 WD repeat domain 61 0.00640841
SPRR2B small proline-rich protein 2B 0.00640351
GSTM3 glutathione S-transferase mu 3 (brain) 0.00637173
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.00636807
MPO myeloperoxidase 0.00635751
DCTN4 dynactin 4 (p62) 0.00635117
RGS10 regulator of G-protein signaling 10 0.00632705
UBE2B ubiquitin-conjugating enzyme E2B 0.00631618
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.00631579
AKR1C2 aldo-keto reductase family 1, member C2 0.00631021
GPC3 glypican 3 0.00630249
JPT1 Jupiter microtubule associated homolog 1 0.0062892
COL15A1 collagen, type XV, alpha 1 0.0062624
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.006255
YPEL5 yippee-like 5 (Drosophila) 0.00624107
FZD6 frizzled class receptor 6 0.00623794
LY96 lymphocyte antigen 96 0.00622263
TUBA4A tubulin, alpha 4a 0.00622254
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00621859
CLIC5 chloride intracellular channel 5 0.00621192
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00620429
SP110 SP110 nuclear body protein 0.00618268
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.00616472
SLC38A1 solute carrier family 38, member 1 0.0061597
LAMA3 laminin, alpha 3 0.00613962
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00613709
PRR4 proline rich 4 (lacrimal) 0.00613256
INHBB inhibin, beta B 0.00612676
CCNG1 cyclin G1 0.0061201
HSPH1 heat shock 105kDa/110kDa protein 1 0.00609854
STK17A serine/threonine kinase 17a 0.00605076
IL1R1 interleukin 1 receptor, type I 0.00604662
ICAM1 intercellular adhesion molecule 1 0.00599783
FRS2 fibroblast growth factor receptor substrate 2 0.00598886
EPS8 epidermal growth factor receptor pathway substrate 8 0.005983
LPAR6 lysophosphatidic acid receptor 6 0.00594365
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00594261
ARHGAP15 Rho GTPase activating protein 15 0.00591614
STK39 serine threonine kinase 39 0.0059125
CLEC3B C-type lectin domain family 3, member B 0.00590468
SLC38A2 solute carrier family 38, member 2 0.00590305
SKP1 S-phase kinase-associated protein 1 0.00588377
MALL mal, T-cell differentiation protein-like 0.00587373
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00586612
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00584853
IL6ST interleukin 6 signal transducer 0.00584505
IGFBP6 insulin-like growth factor binding protein 6 0.00581166
RAB1A RAB1A, member RAS oncogene family 0.00578877
SEPP1 selenoprotein P, plasma, 1 0.00577585
HSPE1 heat shock 10kDa protein 1 0.00573708
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.0057336
RSL1D1 ribosomal L1 domain containing 1 0.00573154
CLEC2B C-type lectin domain family 2, member B 0.00572664
PLAU plasminogen activator, urokinase 0.00571567
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.00571472
SP100 SP100 nuclear antigen 0.00570984
ISG20 interferon stimulated exonuclease gene 20kDa 0.00570439
CNTN1 contactin 1 0.00569799
PDCD10 programmed cell death 10 0.00568939
RSL24D1 ribosomal L24 domain containing 1 0.00568471
CAV1 caveolin 1, caveolae protein, 22kDa 0.00568035
OSMR oncostatin M receptor 0.00567393
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00567094
CCK cholecystokinin 0.00566336
UPP1 uridine phosphorylase 1 0.00565268
BID BH3 interacting domain death agonist 0.00564764
WTAP Wilms tumor 1 associated protein 0.00563869
STC2 stanniocalcin 2 0.00561712
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.00561622
EMP2 epithelial membrane protein 2 0.00560956
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00560952
MRPL18 mitochondrial ribosomal protein L18 0.00560084
DOK5 docking protein 5 0.00559551
NRN1 neuritin 1 0.00559076
DMAC2L distal membrane arm assembly component 2 like 0.00558472
BCAS2 breast carcinoma amplified sequence 2 0.00557966
FGF13 fibroblast growth factor 13 0.00557522
MARCHF5 membrane associated ring-CH-type finger 5 0.00555994
SLC35E3 solute carrier family 35, member E3 0.0055576
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00554446
AKR1C1 aldo-keto reductase family 1, member C1 0.00552775
PLSCR1 phospholipid scramblase 1 0.00550603
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00548865
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00547984
RPS27L ribosomal protein S27-like 0.00546419
PEG10 paternally expressed 10 0.00545663
SLC35G2 solute carrier family 35, member G2 0.0054554
THBS2 thrombospondin 2 0.00543836
SPRR1A small proline-rich protein 1A 0.00543295
MMD monocyte to macrophage differentiation-associated 0.0054326
CFB complement factor B 0.0054321
ZNF395 zinc finger protein 395 0.00542837
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00542311
GMDS GDP-mannose 4,6-dehydratase 0.00541359
BTG3 BTG family, member 3 0.00540102
NMD3 NMD3 ribosome export adaptor 0.00537838
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.00534676
TMEM47 transmembrane protein 47 0.00533507
IL1R2 interleukin 1 receptor, type II 0.00533126
RALB v-ral simian leukemia viral oncogene homolog B 0.00532881
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.00532723
FOLR1 folate receptor 1 (adult) 0.00532289
MDFIC MyoD family inhibitor domain containing 0.00531701
EXOC5 exocyst complex component 5 0.00530681
IDI1 isopentenyl-diphosphate delta isomerase 1 0.00530625
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 0.0053015
ELOC elongin C 0.00529364
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00529121
PPA1 pyrophosphatase (inorganic) 1 0.00528705
HMGA1 high mobility group AT-hook 1 0.00528687
MYO1C myosin IC 0.00528677
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00528655
MECOM MDS1 and EVI1 complex locus 0.00527606
EIF5 eukaryotic translation initiation factor 5 0.00527228
SPRR3 small proline-rich protein 3 0.00526678
IER5 immediate early response 5 0.0052637
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00525947
TFPI2 tissue factor pathway inhibitor 2 0.00525467
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00524777
NFU1 NFU1 iron-sulfur cluster scaffold 0.00524264
BCL10 B-cell CLL/lymphoma 10 0.00523781
ARHGAP29 Rho GTPase activating protein 29 0.00523556
ESD esterase D 0.00522878
DPP4 dipeptidyl-peptidase 4 0.00522867
IRF1 interferon regulatory factor 1 0.00521035
MCUR1 mitochondrial calcium uniporter regulator 1 0.00520414
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00518947
CLU clusterin 0.00517758
PPL periplakin 0.0051648
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.0051553
PLLP plasmolipin 0.00515304
ZFAND1 zinc finger, AN1-type domain 1 0.00515226
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.00514696
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 0.00514359
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.0051328
YIPF5 Yip1 domain family, member 5 0.00511968
CLTB clathrin, light chain B 0.00511891
CD99 CD99 molecule 0.00511628
CEL carboxyl ester lipase 0.00511537
ANXA4 annexin A4 0.00511503
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.00510856
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.00509948
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.00509712
GJA1 gap junction protein, alpha 1, 43kDa 0.00509593
C1QBP complement component 1, q subcomponent binding protein 0.00509294
SNAP25 synaptosomal-associated protein, 25kDa 0.00509135
CCNC cyclin C 0.00508822
VSNL1 visinin-like 1 0.00508652
KLK10 kallikrein-related peptidase 10 0.00508207
EIF1B eukaryotic translation initiation factor 1B 0.00506681
PEX2 peroxisomal biogenesis factor 2 0.00506191
SERINC1 serine incorporator 1 0.00505853
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.00505603
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.00505353
NEU1 sialidase 1 (lysosomal sialidase) 0.00505002
SLC16A4 solute carrier family 16, member 4 0.00504491
CSNK2B casein kinase 2, beta polypeptide 0.00503398
CFH complement factor H 0.00502553
PLIN3 perilipin 3 0.00502399

decreased expression

Symbol Name Standardized Value
TUBB6 tubulin, beta 6 class V -0.0163289
MAP7 microtubule-associated protein 7 -0.0126268
CDC25B cell division cycle 25B -0.0105918
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00991555
RRBP1 ribosome binding protein 1 -0.009603
PTCH1 patched 1 -0.00934208
DAPK1 death-associated protein kinase 1 -0.00909428
APMAP adipocyte plasma membrane associated protein -0.0089067
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00885961
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00882743
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00876147
KLRK1 killer cell lectin-like receptor subfamily K, member 1 -0.00842078
FBP1 fructose-1,6-bisphosphatase 1 -0.0084125
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00830225
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00803861
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00785973
CCL5 chemokine (C-C motif) ligand 5 -0.00785432
SIDT2 SID1 transmembrane family, member 2 -0.00760374
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.00752081
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00749868
GATA3 GATA binding protein 3 -0.00745232
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -0.00744441
ESR1 estrogen receptor 1 -0.00740157
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -0.00729809
TFF3 trefoil factor 3 (intestinal) -0.00719648
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 -0.00718587
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -0.00716901
SFRP1 secreted frizzled-related protein 1 -0.00713693
NKG7 natural killer cell granule protein 7 -0.00713558
MLPH melanophilin -0.00705204
XIC X chromosome inactivation center -0.00702383
F12 coagulation factor XII (Hageman factor) -0.00695449
P4HB prolyl 4-hydroxylase, beta polypeptide -0.00694494
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 -0.00693121
SLCO1B3 solute carrier organic anion transporter family, member 1B3 -0.0068851
GUSB glucuronidase, beta -0.00676858
SPP1 secreted phosphoprotein 1 -0.00674443
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 -0.00667963
HDAC6 histone deacetylase 6 -0.00653309
SCGB1D2 secretoglobin, family 1D, member 2 -0.00652348
DACH1 dachshund family transcription factor 1 -0.00651254
LIG1 ligase I, DNA, ATP-dependent -0.0064958
NES nestin -0.00648747
HYOU1 hypoxia up-regulated 1 -0.0064368
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.00642216
SOX11 SRY (sex determining region Y)-box 11 -0.00639754
FBXO11 F-box protein 11 -0.00637275
HMG20B high mobility group 20B -0.00635285
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -0.00634054
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.00632226
CD8A CD8a molecule -0.00627322
RXRA retinoid X receptor, alpha -0.00625417
ECHDC2 enoyl CoA hydratase domain containing 2 -0.00622723
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00619547
BCHE butyrylcholinesterase -0.00615654
SCGB2A2 secretoglobin, family 2A, member 2 -0.00615213
TFF1 trefoil factor 1 -0.00607431
ICMT isoprenylcysteine carboxyl methyltransferase -0.00605505
NUSAP1 nucleolar and spindle associated protein 1 -0.00603781
ASPN asporin -0.00598685
FANCL Fanconi anemia, complementation group L -0.00597394
C9 complement component 9 -0.00596734
TRAF5 TNF receptor-associated factor 5 -0.00595178
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 -0.00592916
ELP1 elongator acetyltransferase complex subunit 1 -0.00592675
TLE4 transducin-like enhancer of split 4 -0.00589287
CPB1 carboxypeptidase B1 (tissue) -0.00586976
TMSB15A thymosin beta 15a -0.0058563
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 -0.00584198
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.00584043
EFNB2 ephrin-B2 -0.00583963
RAD23B RAD23 homolog B (S. cerevisiae) -0.00581558
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00577903
ANKRD10 ankyrin repeat domain 10 -0.00576267
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -0.00573862
PNPLA6 patatin-like phospholipase domain containing 6 -0.0057247
RALGDS ral guanine nucleotide dissociation stimulator -0.00571691
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00571459
FCGBP Fc fragment of IgG binding protein -0.0057128
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) -0.00570555
OLFM4 olfactomedin 4 -0.00569894
DEFA5 defensin, alpha 5, Paneth cell-specific -0.00568115
NTS neurotensin -0.00567915
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 -0.00566028
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.005653
EPHB2 EPH receptor B2 -0.00565106
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 -0.00564819
FGFR3 fibroblast growth factor receptor 3 -0.00564096
ANXA6 annexin A6 -0.00563847
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00562386
ACADVL acyl-CoA dehydrogenase, very long chain -0.00559057
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -0.00558442
INSM1 insulinoma-associated 1 -0.00557903
GYS2 glycogen synthase 2 (liver) -0.00557247
KLRF1 killer cell lectin-like receptor subfamily F, member 1 -0.00555945
LECT2 leukocyte cell-derived chemotaxin 2 -0.00554742
CD9 CD9 molecule -0.00554638
GANAB glucosidase, alpha; neutral AB -0.00554451
NUCB1 nucleobindin 1 -0.00554123
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00552742
PBX1 pre-B-cell leukemia homeobox 1 -0.00548177
MSN moesin -0.00547835
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 -0.00543829
KLRD1 killer cell lectin-like receptor subfamily D, member 1 -0.00541478
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00540832
SEC16A SEC16 homolog A (S. cerevisiae) -0.00540711
SPEN spen family transcriptional repressor -0.00540649
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -0.00537401
TTC38 tetratricopeptide repeat domain 38 -0.00535074
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -0.00534459
AKT1 v-akt murine thymoma viral oncogene homolog 1 -0.00533696
MFAP2 microfibrillar-associated protein 2 -0.00531686
TRAPPC3 trafficking protein particle complex 3 -0.00531375
EML3 echinoderm microtubule associated protein like 3 -0.00530562
GNLY granulysin -0.00529764
PRF1 perforin 1 (pore forming protein) -0.0052627
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.00525743
BASP1 brain abundant, membrane attached signal protein 1 -0.00524458
ADH6 alcohol dehydrogenase 6 (class V) -0.00524113
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00522674
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00521181
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00521055
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00519683
LMNB2 lamin B2 -0.00517811
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.00516515
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00516266
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00516186
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.00514991
MAGEA4 melanoma antigen family A4 -0.00514727
NFASC neurofascin -0.00512733
CHIC2 cysteine-rich hydrophobic domain 2 -0.00511972
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.00511408
TGM2 transglutaminase 2 -0.00511256
CCR1 chemokine (C-C motif) receptor 1 -0.00509756
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -0.00509411
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -0.00508385
MLEC malectin -0.00508183
TBC1D4 TBC1 domain family, member 4 -0.00507563
CSAD cysteine sulfinic acid decarboxylase -0.00506525
WEE1 WEE1 G2 checkpoint kinase -0.00503405
MTA1 metastasis associated 1 -0.00501041
IGFBP1 insulin-like growth factor binding protein 1 -0.00500563
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00500558
DMPK dystrophia myotonica-protein kinase -0.00500402
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.00500275
FOXM1 forkhead box M1 -0.0049908
OBSL1 obscurin-like 1 -0.00497703
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 -0.00495598
LONP2 lon peptidase 2, peroxisomal -0.00495231
C8ORF4 chromosome 8 open reading frame 4 -0.00494787
ANGPTL3 angiopoietin-like 3 -0.004947
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -0.00494666
WT1 Wilms tumor 1 -0.00493254
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -0.00491803
FOXE1 forkhead box E1 -0.00491618
C2CD5 C2 calcium-dependent domain containing 5 -0.0049133
NOVA1 neuro-oncological ventral antigen 1 -0.00491124
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.00490614
ENO2 enolase 2 (gamma, neuronal) -0.00490606
PON3 paraoxonase 3 -0.00490199
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -0.00488152
GSAP gamma-secretase activating protein -0.00486356
MMP9 matrix metallopeptidase 9 -0.0048616
PTK7 protein tyrosine kinase 7 (inactive) -0.00482861
NR1I2 nuclear receptor subfamily 1, group I, member 2 -0.00482852
CBR4 carbonyl reductase 4 -0.00482817
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 -0.00482736
BCOR BCL6 corepressor -0.0048265
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -0.00482272
NOP53 NOP53 ribosome biogenesis factor -0.00481159
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.0047994
IL2RB interleukin 2 receptor, beta -0.00479467
CST7 cystatin F (leukocystatin) -0.0047942
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00478767
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -0.00478001
PHF1 PHD finger protein 1 -0.00477813
RPA1 replication protein A1, 70kDa -0.00477768
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00476784
MTMR11 myotubularin related protein 11 -0.00476719
IGFBP4 insulin-like growth factor binding protein 4 -0.00475854
ATG4B autophagy related 4B, cysteine peptidase -0.00475708
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00475136
TRIM44 tripartite motif containing 44 -0.00474696
APOF apolipoprotein F -0.00472261
KLRC3 killer cell lectin-like receptor subfamily C, member 3 -0.00471522
MTTP microsomal triglyceride transfer protein -0.004713
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.0047054
KIF20A kinesin family member 20A -0.00470421
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 -0.00470329
ZBTB38 zinc finger and BTB domain containing 38 -0.00469338
ATF5 activating transcription factor 5 -0.00469097
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.00468443
E2F2 E2F transcription factor 2 -0.00468284
MAGED1 melanoma antigen family D1 -0.00467641
EPHX2 epoxide hydrolase 2, cytoplasmic -0.00467199
RBM6 RNA binding motif protein 6 -0.00466998
LONP1 lon peptidase 1, mitochondrial -0.00466924
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00466739
FEN1 flap structure-specific endonuclease 1 -0.00465892
TRRAP transformation/transcription domain-associated protein -0.00465553
NANOG Nanog homeobox -0.00465015
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -0.00463765
PRAME preferentially expressed antigen in melanoma -0.00463609
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic -0.0046329
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -0.00461942
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -0.00460945
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00459812
DPYSL3 dihydropyrimidinase-like 3 -0.00459366
DIO1 deiodinase, iodothyronine, type I -0.00458614
MCOLN1 mucolipin 1 -0.00458313
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 -0.00458181
GPR18 G protein-coupled receptor 18 -0.00458067
ACTN1 actinin, alpha 1 -0.00457943
GRAMD1C GRAM domain containing 1C -0.00456788
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -0.00456575
AGR2 anterior gradient 2 -0.00455152
CFHR4 complement factor H-related 4 -0.00455141
POU2AF1 POU class 2 associating factor 1 -0.00453567
REG3A regenerating islet-derived 3 alpha -0.00453538
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 -0.00453104
KANK2 KN motif and ankyrin repeat domains 2 -0.00452464
KHK ketohexokinase (fructokinase) -0.00452362
PDHX pyruvate dehydrogenase complex, component X -0.00452073
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00451546
GOLM1 golgi membrane protein 1 -0.0045109
SLC38A4 solute carrier family 38, member 4 -0.00450958
FMO3 flavin containing monooxygenase 3 -0.00450295
PLAT plasminogen activator, tissue -0.00449381
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00449083
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 -0.00448926
ZBTB20 zinc finger and BTB domain containing 20 -0.00446532
GCLC glutamate-cysteine ligase, catalytic subunit -0.00445441
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -0.00445114
ZNF518A zinc finger protein 518A -0.00444749
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -0.00444312
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00443835
PTPRD protein tyrosine phosphatase, receptor type, D -0.00443461
DLK1 delta-like 1 homolog (Drosophila) -0.00442955
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -0.00442885
RAB38 RAB38, member RAS oncogene family -0.00442793
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -0.00442556
RETREG3 reticulophagy regulator family member 3 -0.00441521
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00441138
CRHBP corticotropin releasing hormone binding protein -0.00440974
EPCAM epithelial cell adhesion molecule -0.00440704
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.00440537
PCCB propionyl CoA carboxylase, beta polypeptide -0.00439494
NCOR1 nuclear receptor corepressor 1 -0.00439311
CHD4 chromodomain helicase DNA binding protein 4 -0.00438093
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -0.00437366