SIRT2 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description sirtuin 2|This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010] (NCBI Entrez Gene Database, 22933)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GCM_SIRT2
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Genes

43 co-expressed genes for SIRT2 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ANKFY1 ankyrin repeat and FYVE domain containing 1
C1ORF198 chromosome 1 open reading frame 198
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDHD2 DDHD domain containing 2
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EFCAB14 EF-hand calcium binding domain 14
EPT1 ethanolaminephosphotransferase 1
FAM219A family with sequence similarity 219, member A
FBXW11 F-box and WD repeat domain containing 11
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GLTP glycolipid transfer protein
GOLGA7 golgin A7
GORASP1 golgi reassembly stacking protein 1, 65kDa
IL6ST interleukin 6 signal transducer
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KIF3B kinesin family member 3B
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
METTL7A methyltransferase like 7A
MFN2 mitofusin 2
MRVI1 murine retrovirus integration site 1 homolog
MTUS1 microtubule associated tumor suppressor 1
MYO10 myosin X
MYO9A myosin IXA
PDE4DIP phosphodiesterase 4D interacting protein
PEAK1 pseudopodium-enriched atypical kinase 1
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
RTN4 reticulon 4
SCAMP5 secretory carrier membrane protein 5
SCD5 stearoyl-CoA desaturase 5
SEC14L2 SEC14-like 2 (S. cerevisiae)
SIRT2 sirtuin 2
SNX27 sorting nexin family member 27
TMEM30A transmembrane protein 30A
TNK2 tyrosine kinase, non-receptor, 2
TNS2 tensin 2
UBL3 ubiquitin-like 3
WSB1 WD repeat and SOCS box containing 1
ZNF710 zinc finger protein 710