SK-ES-1 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: sarcoma (anaplastic osteosarcoma or Ewings sarcoma) (Cell Line Ontology, CLO_0009036)
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Genes

240 genes mutated in the SK-ES-1 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ACAD8 acyl-CoA dehydrogenase family, member 8
ACSL5 acyl-CoA synthetase long-chain family member 5
ACSM2B acyl-CoA synthetase medium-chain family member 2B
ACSM4 acyl-CoA synthetase medium-chain family member 4
ADNP activity-dependent neuroprotector homeobox
AGBL5 ATP/GTP binding protein-like 5
AHNAK2 AHNAK nucleoprotein 2
AMPD1 adenosine monophosphate deaminase 1
ANKAR ankyrin and armadillo repeat containing
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APOBR apolipoprotein B receptor
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGAP15 Rho GTPase activating protein 15
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL4P ADP-ribosylation factor-like 4 pseudogene
ATP11B ATPase, class VI, type 11B
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BCL9L B-cell CLL/lymphoma 9-like
C2CD5 C2 calcium-dependent domain containing 5
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCDC180 coiled-coil domain containing 180
CDH26 cadherin 26
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CENPT centromere protein T
CER1 cerberus 1, DAN family BMP antagonist
CHD5 chromodomain helicase DNA binding protein 5
CHKA choline kinase alpha
CHL1 cell adhesion molecule L1-like
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLK4 CDC-like kinase 4
CLRN3 clarin 3
CMYA5 cardiomyopathy associated 5
COLEC10 collectin sub-family member 10 (C-type lectin)
CSMD2 CUB and Sushi multiple domains 2
CUTC cutC copper transporter
CYBB cytochrome b-245, beta polypeptide
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DMTN dematin actin binding protein
DNAH5 dynein, axonemal, heavy chain 5
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DOCK5 dedicator of cytokinesis 5
DOPEY2 dopey family member 2
DQX1 DEAQ box RNA-dependent ATPase 1
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
EML4 echinoderm microtubule associated protein like 4
EPAS1 endothelial PAS domain protein 1
EPCAM epithelial cell adhesion molecule
ESAM endothelial cell adhesion molecule
ESYT1 extended synaptotagmin-like protein 1
FADS6 fatty acid desaturase 6
FAM149A family with sequence similarity 149, member A
FAM161A family with sequence similarity 161, member A
FAM63A family with sequence similarity 63, member A
FASTKD5 FAST kinase domains 5
FCAMR Fc receptor, IgA, IgM, high affinity
FGD3 FYVE, RhoGEF and PH domain containing 3
FHL2 four and a half LIM domains 2
FKBP15 FK506 binding protein 15, 133kDa
FKBP6 FK506 binding protein 6, 36kDa
FLAD1 flavin adenine dinucleotide synthetase 1
FNDC3B fibronectin type III domain containing 3B
GCLM glutamate-cysteine ligase, modifier subunit
GGT1 gamma-glutamyltransferase 1
GLG1 golgi glycoprotein 1
GOLGA1 golgin A1
GPR149 G protein-coupled receptor 149
GPRASP2 G protein-coupled receptor associated sorting protein 2
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRN granulin
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GUSB glucuronidase, beta
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HOMEZ homeobox and leucine zipper encoding
HSF1 heat shock transcription factor 1
HYDIN HYDIN, axonemal central pair apparatus protein
INPPL1 inositol polyphosphate phosphatase-like 1
IPO5 importin 5
IQGAP1 IQ motif containing GTPase activating protein 1
IRF6 interferon regulatory factor 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
ITSN2 intersectin 2
KATNAL1 katanin p60 subunit A-like 1
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCTD9P2 potassium channel tetramerization domain containing 9 pseudogene 2
KIAA0355 KIAA0355
KIAA1671 KIAA1671
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KRT8P11 keratin 8 pseudogene 11
KRTAP4-6 keratin associated protein 4-6
LAMA4 laminin, alpha 4
LAMB4 laminin, beta 4
LIG4 ligase IV, DNA, ATP-dependent
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LOC541473 FK506 binding protein 6, 36kDa pseudogene
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC34 leucine rich repeat containing 34
LRRC53 leucine rich repeat containing 53
LRRK2 leucine-rich repeat kinase 2
LTK leukocyte receptor tyrosine kinase
LYPD4 LY6/PLAUR domain containing 4
MATN4 matrilin 4
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MMP11 matrix metallopeptidase 11
MON2 MON2 homolog (S. cerevisiae)
MRPL37 mitochondrial ribosomal protein L37
MTNR1B melatonin receptor 1B
MTPAP mitochondrial poly(A) polymerase
MUC12 mucin 12, cell surface associated
MUC15 mucin 15, cell surface associated
MUC4 mucin 4, cell surface associated
MYLK myosin light chain kinase
MYO9B myosin IXB
MYOM2 myomesin 2
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NBEAL2 neurobeachin-like 2
NCAN neurocan
NEB nebulin
NEK10 NIMA-related kinase 10
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NKAIN4 Na+/K+ transporting ATPase interacting 4
NLN neurolysin (metallopeptidase M3 family)
NLRP11 NLR family, pyrin domain containing 11
NOL6 nucleolar protein 6 (RNA-associated)
NOX3 NADPH oxidase 3
NR2C1 nuclear receptor subfamily 2, group C, member 1
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17
NVL nuclear VCP-like
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OR2T27 olfactory receptor, family 2, subfamily T, member 27
OR4D5 olfactory receptor, family 4, subfamily D, member 5
OR52E8 olfactory receptor, family 52, subfamily E, member 8
OR52J3 olfactory receptor, family 52, subfamily J, member 3
OR6X1 olfactory receptor, family 6, subfamily X, member 1
OR8B8 olfactory receptor, family 8, subfamily B, member 8
OTUD7A OTU deubiquitinase 7A
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PARD3B par-3 family cell polarity regulator beta
PARP12 poly (ADP-ribose) polymerase family, member 12
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDZD2 PDZ domain containing 2
PEAR1 platelet endothelial aggregation receptor 1
PEX5 peroxisomal biogenesis factor 5
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCH1 phospholipase C, eta 1
PLEKHA7 pleckstrin homology domain containing, family A member 7
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PRC1 protein regulator of cytokinesis 1
PRDM11 PR domain containing 11
PRLR prolactin receptor
PRMT9 protein arginine methyltransferase 9
PROKR1 prokineticin receptor 1
PRUNE2 prune homolog 2 (Drosophila)
PSKH2 protein serine kinase H2
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PTGIS prostaglandin I2 (prostacyclin) synthase
PTHLH parathyroid hormone-like hormone
QPCTL glutaminyl-peptide cyclotransferase-like
RICTOR RPTOR independent companion of MTOR, complex 2
RIF1 replication timing regulatory factor 1
RIOK2 RIO kinase 2
RLN2 relaxin 2
RNF14 ring finger protein 14
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RORA RAR-related orphan receptor A
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RUNX2 runt-related transcription factor 2
SALL4 spalt-like transcription factor 4
SCARB2 scavenger receptor class B, member 2
SEC14L3 SEC14-like 3 (S. cerevisiae)
SFRP2 secreted frizzled-related protein 2
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC12A9 solute carrier family 12, member 9
SOX2 SRY (sex determining region Y)-box 2
SPTA1 spectrin, alpha, erythrocytic 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
STAB2 stabilin 2
STAG2 stromal antigen 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STIM2 stromal interaction molecule 2
STRA6 stimulated by retinoic acid 6
STRAP serine/threonine kinase receptor associated protein
STX18 syntaxin 18
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYT14 synaptotagmin XIV
TACR3 tachykinin receptor 3
TASP1 taspase, threonine aspartase, 1
TCF19 transcription factor 19
TDO2 tryptophan 2,3-dioxygenase
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TMEM39A transmembrane protein 39A
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53 tumor protein p53
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRHDE thyrotropin-releasing hormone degrading enzyme
TRIM40 tripartite motif containing 40
TRIM55 tripartite motif containing 55
TTC25 tetratricopeptide repeat domain 25
TTC27 tetratricopeptide repeat domain 27
TTC39A tetratricopeptide repeat domain 39A
TTN titin
TUFM Tu translation elongation factor, mitochondrial
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3
URGCP upregulator of cell proliferation
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
VEZT vezatin, adherens junctions transmembrane protein
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
VSTM2B V-set and transmembrane domain containing 2B
WDR48 WD repeat domain 48
WDR66 WD repeat domain 66
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WIPF1 WAS/WASL interacting protein family, member 1
XDH xanthine dehydrogenase
ZACN zinc activated ligand-gated ion channel
ZFPM2 zinc finger protein, FOG family member 2
ZNF157 zinc finger protein 157
ZNF433 zinc finger protein 433
ZNF534 zinc finger protein 534
ZNF596 zinc finger protein 596
ZNF7 zinc finger protein 7