SK-MEL-28 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

87 genes mutated in the SK-MEL-28 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
APC adenomatous polyposis coli
APOBEC3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGAP31 Rho GTPase activating protein 31
ARID1A AT rich interactive domain 1A (SWI-like)
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
ATP5J2-PTCD1 ATP5J2-PTCD1 readthrough
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BLM Bloom syndrome, RecQ helicase-like
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1ORF27 chromosome 1 open reading frame 27
C5ORF42 chromosome 5 open reading frame 42
CANX calnexin
CARF calcium responsive transcription factor
CCDC36 coiled-coil domain containing 36
CD63 CD63 molecule
CERS1 ceramide synthase 1
CHKA choline kinase alpha
CLEC2B C-type lectin domain family 2, member B
COL11A1 collagen, type XI, alpha 1
COL19A1 collagen, type XIX, alpha 1
DNM2 dynamin 2
DST dystonin
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EP400 E1A binding protein p400
FAM173A family with sequence similarity 173, member A
FAT1 FAT atypical cadherin 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GGT7 gamma-glutamyltransferase 7
GMPR2 guanosine monophosphate reductase 2
GOLGB1 golgin B1
GPC6 glypican 6
GRIPAP1 GRIP1 associated protein 1
HDAC1 histone deacetylase 1
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
IFT140 intraflagellar transport 140
IL17RA interleukin 17 receptor A
ILF3 interleukin enhancer binding factor 3, 90kDa
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
JAK2 Janus kinase 2
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAGEC1 melanoma antigen family C1
MAN1B1 mannosidase, alpha, class 1B, member 1
MED25 mediator complex subunit 25
MFSD3 major facilitator superfamily domain containing 3
MRPL4 mitochondrial ribosomal protein L4
MTM1 myotubularin 1
NFXL1 nuclear transcription factor, X-box binding-like 1
ODF2 outer dense fiber of sperm tails 2
PHRF1 PHD and ring finger domains 1
PIGG phosphatidylinositol glycan anchor biosynthesis, class G
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
PLXNB3 plexin B3
PPAP2B phosphatidic acid phosphatase type 2B
PROS1 protein S (alpha)
PTEN phosphatase and tensin homolog
QSOX2 quiescin Q6 sulfhydryl oxidase 2
REPS1 RALBP1 associated Eps domain containing 1
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
SACS sacsin molecular chaperone
SCAF1 SR-related CTD-associated factor 1
SEC24D SEC24 family member D
SEPT10 septin 10
SH3PXD2A SH3 and PX domains 2A
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNRK SNF related kinase
SOGA1 suppressor of glucose, autophagy associated 1
SYCP2 synaptonemal complex protein 2
SYNE1 spectrin repeat containing, nuclear envelope 1
TK2 thymidine kinase 2, mitochondrial
TP53 tumor protein p53
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UBN1 ubinuclein 1
USP19 ubiquitin specific peptidase 19
USP54 ubiquitin specific peptidase 54
VASP vasodilator-stimulated phosphoprotein
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZEB2 zinc finger E-box binding homeobox 2
ZNF613 zinc finger protein 613
ZNHIT6 zinc finger, HIT-type containing 6
ZSCAN21 zinc finger and SCAN domain containing 21
ZSWIM8 zinc finger, SWIM-type containing 8