SKCO1 Gene Set

Dataset Achilles Cell Line Gene Essentiality Profiles
Category disease or phenotype associations
Type cell line
Description disease: colorectal adenocarcinoma (colon primary) (Cell Line Ontology, CLO_0009035)
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Genes

858 gene knockdowns changing fitness of SKCO1 relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.

increased fitness

Symbol Name Standardized Value
BCL2 B-cell CLL/lymphoma 2 3.19303
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 3.19303
NMBR neuromedin B receptor 3.19224
CNOT4 CCR4-NOT transcription complex, subunit 4 3.18955
OXCT1 3-oxoacid CoA transferase 1 3.18549
ZNF154 zinc finger protein 154 3.18357
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 3.17055
TAS2R42 taste receptor, type 2, member 42 3.1625
SLIT2 slit homolog 2 (Drosophila) 3.03132
MKX mohawk homeobox 2.99868
TRIM13 tripartite motif containing 13 2.97769
TUFT1 tuftelin 1 2.96669
GUCA1A guanylate cyclase activator 1A (retina) 2.92533
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 2.87588
COG3 component of oligomeric golgi complex 3 2.82359
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.76799
SLAMF1 signaling lymphocytic activation molecule family member 1 2.65733
B3GAT2 beta-1,3-glucuronyltransferase 2 2.65013
USP17L1 ubiquitin specific peptidase 17-like family member 1 2.64752
STON1 stonin 1 2.61041
PXK PX domain containing serine/threonine kinase 2.58983
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 2.55819
IFT27 intraflagellar transport 27 2.5336
TCL1A T-cell leukemia/lymphoma 1A 2.48893
HCAR2 hydroxycarboxylic acid receptor 2 2.4223
SIN3A SIN3 transcription regulator family member A 2.37917
STRN striatin, calmodulin binding protein 2.36192
DHRS4 dehydrogenase/reductase (SDR family) member 4 2.33583
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 2.29408
CLIP1 CAP-GLY domain containing linker protein 1 2.28687
MLKL mixed lineage kinase domain-like 2.24318
CCL7 chemokine (C-C motif) ligand 7 2.24232
REXO2 RNA exonuclease 2 2.22144
C1QA complement component 1, q subcomponent, A chain 2.20565
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 2.16088
INTS3 integrator complex subunit 3 2.14387
STRADA STE20-related kinase adaptor alpha 2.13937
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 2.11044
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1 2.10761
CPQ carboxypeptidase Q 2.08407
PTP4A2 protein tyrosine phosphatase type IVA, member 2 2.07244
S1PR5 sphingosine-1-phosphate receptor 5 2.06702
PRSS35 protease, serine, 35 2.06349
TARBP1 TAR (HIV-1) RNA binding protein 1 2.06228
FBXO21 F-box protein 21 2.06187
ZNF100 zinc finger protein 100 2.0382
NTSR2 neurotensin receptor 2 2.03747
LY75 lymphocyte antigen 75 2.03688
DICER1 dicer 1, ribonuclease type III 2.02986
PTER phosphotriesterase related 2.01872
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 2.01599
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) 1.99598
HBE1 hemoglobin, epsilon 1 1.9908
ARID4A AT rich interactive domain 4A (RBP1-like) 1.98434
SOX10 SRY (sex determining region Y)-box 10 1.97781
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.96468
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 1.9634
NEFL neurofilament, light polypeptide 1.95005
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 1.94888
COX7B2 cytochrome c oxidase subunit VIIb2 1.94664
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 1.94231
CCNC cyclin C 1.93748
SYNRG synergin, gamma 1.92774
NLRP3 NLR family, pyrin domain containing 3 1.91914
MARCO macrophage receptor with collagenous structure 1.91416
ARL13B ADP-ribosylation factor-like 13B 1.89731
IL27RA interleukin 27 receptor, alpha 1.88861
NFIB nuclear factor I/B 1.88841
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene) 1.87671
PZP pregnancy-zone protein 1.87603
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 1.87545
OR2T5 olfactory receptor, family 2, subfamily T, member 5 1.8702
ARHGAP26 Rho GTPase activating protein 26 1.86364
CD163 CD163 molecule 1.85898
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 1.85876
ACAT2 acetyl-CoA acetyltransferase 2 1.85171
TASP1 taspase, threonine aspartase, 1 1.84485
CTSA cathepsin A 1.84427
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 1.83965
RPP25 ribonuclease P/MRP 25kDa subunit 1.8394
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 1.83548
PREPL prolyl endopeptidase-like 1.83521
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 1.82884
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.82836
PGLS 6-phosphogluconolactonase 1.81449
RNF212 ring finger protein 212 1.79298
GPR151 G protein-coupled receptor 151 1.76919
TAS2R9 taste receptor, type 2, member 9 1.76842
NRIP1 nuclear receptor interacting protein 1 1.75885
ACVR2B activin A receptor, type IIB 1.75756
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 1.75375
ETV1 ets variant 1 1.74801
KRT12 keratin 12, type I 1.7449
SLC10A5 solute carrier family 10, member 5 1.73958
CD300C CD300c molecule 1.7324
NAE1 NEDD8 activating enzyme E1 subunit 1 1.71684
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 1.69399
OR51F2 olfactory receptor, family 51, subfamily F, member 2 1.69075
ZNF566 zinc finger protein 566 1.68422
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 1.68301
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 1.68063
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 1.67832
PLSCR1 phospholipid scramblase 1 1.67793
NUP107 nucleoporin 107kDa 1.6732
FZD4 frizzled class receptor 4 1.67187
RGS17 regulator of G-protein signaling 17 1.65231
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 1.64871
MNX1 motor neuron and pancreas homeobox 1 1.64783
NID1 nidogen 1 1.64187
DPEP2 dipeptidase 2 1.63442
SCN1A sodium channel, voltage gated, type I alpha subunit 1.63307
SCYL3 SCY1-like 3 (S. cerevisiae) 1.63278
ATG4B autophagy related 4B, cysteine peptidase 1.62734
KNG1 kininogen 1 1.62371
NCAN neurocan 1.62289
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.62276
GPR142 G protein-coupled receptor 142 1.61904
PRG3 proteoglycan 3 1.6056
GIPR gastric inhibitory polypeptide receptor 1.60487
AMY2A amylase, alpha 2A (pancreatic) 1.60426
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 1.60377
MC5R melanocortin 5 receptor 1.60283
ZNF22 zinc finger protein 22 1.60273
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 1.5983
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 1.59702
BCOR BCL6 corepressor 1.59168
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 1.59084
STK35 serine/threonine kinase 35 1.58946
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 1.58891
AIF1L allograft inflammatory factor 1-like 1.57833
GYS1 glycogen synthase 1 (muscle) 1.57832
KLRC2 killer cell lectin-like receptor subfamily C, member 2 1.57729
TRPV5 transient receptor potential cation channel, subfamily V, member 5 1.57699
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 1.57614
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 1.57478
SLC25A27 solute carrier family 25, member 27 1.56846
RNASE6 ribonuclease, RNase A family, k6 1.56706
R3HDM2 R3H domain containing 2 1.56273
TRPS1 trichorhinophalangeal syndrome I 1.56179
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.5606
CD302 CD302 molecule 1.55991
TCF20 transcription factor 20 (AR1) 1.55098
STEAP3 STEAP family member 3, metalloreductase 1.54607
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 1.5439
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 1.54033
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 1.53668
RNF7 ring finger protein 7 1.5294
TRIM31 tripartite motif containing 31 1.52832
ADSSL1 adenylosuccinate synthase like 1 1.52556
S100A3 S100 calcium binding protein A3 1.51332
F2RL1 coagulation factor II (thrombin) receptor-like 1 1.51113
OR7E5P olfactory receptor, family 7, subfamily E, member 5 pseudogene 1.51048
TSC22D4 TSC22 domain family, member 4 1.50994
PTGER3 prostaglandin E receptor 3 (subtype EP3) 1.50779
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 1.50524
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 1.50092
FLNB filamin B, beta 1.49979
SSX8 synovial sarcoma, X breakpoint 8 1.49485
WHSC1 Wolf-Hirschhorn syndrome candidate 1 1.49355
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 1.49259
WTAP Wilms tumor 1 associated protein 1.49202
FGF17 fibroblast growth factor 17 1.49177
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 1.49077
DPRX divergent-paired related homeobox 1.49067
RNF39 ring finger protein 39 1.48254
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 1.48135
RALBP1 ralA binding protein 1 1.47655
USP17L3 ubiquitin specific peptidase 17-like family member 3 1.47149
SPATA8 spermatogenesis associated 8 1.47085
STK32C serine/threonine kinase 32C 1.46751
GTF2IRD1 GTF2I repeat domain containing 1 1.4619
VIM vimentin 1.46047
CDH13 cadherin 13 1.45737
ABCC13 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene 1.4566
LAMA3 laminin, alpha 3 1.45599
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 1.45455
RAB28 RAB28, member RAS oncogene family 1.4476
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 1.44728
CXORF23 chromosome X open reading frame 23 1.44238
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 1.44219
NONO non-POU domain containing, octamer-binding 1.44066
CENPN centromere protein N 1.43016
IDI1 isopentenyl-diphosphate delta isomerase 1 1.4272
ABHD10 abhydrolase domain containing 10 1.42705
TRIM26 tripartite motif containing 26 1.42702
MPL MPL proto-oncogene, thrombopoietin receptor 1.42694
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 1.42258
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 1.42196
DDHD2 DDHD domain containing 2 1.42002
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6 1.41685
FGD5 FYVE, RhoGEF and PH domain containing 5 1.4115
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 1.41115
ATP10A ATPase, class V, type 10A 1.40818
SQRDL sulfide quinone reductase-like (yeast) 1.39984
AGTR1 angiotensin II receptor, type 1 1.39796
PCDHB4 protocadherin beta 4 1.39504
ZNF16 zinc finger protein 16 1.38634
EZR ezrin 1.38549
SULT4A1 sulfotransferase family 4A, member 1 1.38201
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 1.38151
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1 1.37961
GFPT1 glutamine--fructose-6-phosphate transaminase 1 1.37815
TGIF2 TGFB-induced factor homeobox 2 1.37807
CLDN18 claudin 18 1.37774
MPPE1 metallophosphoesterase 1 1.37481
ENC1 ectodermal-neural cortex 1 (with BTB domain) 1.37443
DNAI1 dynein, axonemal, intermediate chain 1 1.37155
OR2T12 olfactory receptor, family 2, subfamily T, member 12 1.37078
ZBTB33 zinc finger and BTB domain containing 33 1.36942
SSH3 slingshot protein phosphatase 3 1.36151
ANXA7 annexin A7 1.35962
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 1.35783
TGIF1 TGFB-induced factor homeobox 1 1.35536
MON1B MON1 secretory trafficking family member B 1.35365
EPC1 enhancer of polycomb homolog 1 (Drosophila) 1.35271
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 1.35243
IFT54 intraflagellar transport 54 1.35121
RNMTL1 RNA methyltransferase like 1 1.34703
NUMB numb homolog (Drosophila) 1.34701
RB1 retinoblastoma 1 1.34574
ACOX3 acyl-CoA oxidase 3, pristanoyl 1.34202
GNS glucosamine (N-acetyl)-6-sulfatase 1.33987
CD79A CD79a molecule, immunoglobulin-associated alpha 1.33844
USP17L4 ubiquitin specific peptidase 17-like family member 4 1.33785
CALN1 calneuron 1 1.33767
TFB2M transcription factor B2, mitochondrial 1.33537
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 1.33312
ELAC1 elaC ribonuclease Z 1 1.32861
PHF6 PHD finger protein 6 1.32504
ADRA1B adrenoceptor alpha 1B 1.32323
CUL9 cullin 9 1.30815
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.30645
IL10RB interleukin 10 receptor, beta 1.30377
VILL villin-like 1.30262
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) 1.2988
TIPE2 TNF alpha induced protein 8 like 2 1.29858
COL14A1 collagen, type XIV, alpha 1 1.29834
MAP3K14 mitogen-activated protein kinase kinase kinase 14 1.29616
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 1.29444
AGTRAP angiotensin II receptor-associated protein 1.29086
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.29083
ACYP1 acylphosphatase 1, erythrocyte (common) type 1.29075
ZNF569 zinc finger protein 569 1.28964
CETN3 centrin, EF-hand protein, 3 1.28259
KRT19 keratin 19, type I 1.28231
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.28215
DMRT1 doublesex and mab-3 related transcription factor 1 1.2814
SRPR signal recognition particle receptor (docking protein) 1.28089
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 1.27725
HESX1 HESX homeobox 1 1.27714
BST2 bone marrow stromal cell antigen 2 1.27684
RBPJ recombination signal binding protein for immunoglobulin kappa J region 1.27656
KDM3A lysine (K)-specific demethylase 3A 1.27615
NPTN neuroplastin 1.27106
C8A complement component 8, alpha polypeptide 1.27062
TAS2R20 taste receptor, type 2, member 20 1.26892
ACTL8 actin-like 8 1.26459
CHGA chromogranin A 1.25613
GIMAP4 GTPase, IMAP family member 4 1.25512
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 1.25228
RNF167 ring finger protein 167 1.25167
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1.2463
MBD1 methyl-CpG binding domain protein 1 1.24345
CTRL chymotrypsin-like 1.24263
KLK1 kallikrein 1 1.24262
TAS2R14 taste receptor, type 2, member 14 1.23802
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 1.23587
RHD Rh blood group, D antigen 1.23498
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 1.22785
DOPEY1 dopey family member 1 1.22675
PLAGL2 pleiomorphic adenoma gene-like 2 1.22382
OR4K17 olfactory receptor, family 4, subfamily K, member 17 1.22298
TMED6 transmembrane emp24 protein transport domain containing 6 1.21703
LYPLA1 lysophospholipase I 1.21514
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 1.21377
RSPRY1 ring finger and SPRY domain containing 1 1.21359
OR1E1 olfactory receptor, family 1, subfamily E, member 1 1.21112
UBE2A ubiquitin-conjugating enzyme E2A 1.21066
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.20867
THRB thyroid hormone receptor, beta 1.20821
LRP12 low density lipoprotein receptor-related protein 12 1.20664
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 1.20525
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 1.20323
RNF19B ring finger protein 19B 1.2031
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.20305
CPA4 carboxypeptidase A4 1.20284
MSRA methionine sulfoxide reductase A 1.19441
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 1.19422
ATXN7 ataxin 7 1.19358
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 1.19296
GPR15 G protein-coupled receptor 15 1.19207
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 1.18977
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 1.18655
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 1.18632
UBQLN1 ubiquilin 1 1.18454
INTS12 integrator complex subunit 12 1.18286
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 1.18172
PLCZ1 phospholipase C, zeta 1 1.18106
DLX3 distal-less homeobox 3 1.17915
PRSS48 protease, serine, 48 1.1788
RNPEP arginyl aminopeptidase (aminopeptidase B) 1.1782
CD109 CD109 molecule 1.17789
ZNF680 zinc finger protein 680 1.17524
NEK5 NIMA-related kinase 5 1.17315
TYROBP TYRO protein tyrosine kinase binding protein 1.16852
SHFM1 split hand/foot malformation (ectrodactyly) type 1 1.16676
ARHGAP15 Rho GTPase activating protein 15 1.16531
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 1.16342
NGB neuroglobin 1.16164
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 1.15555
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.15531
CCNJ cyclin J 1.15482
ERCC2 excision repair cross-complementation group 2 1.15402
KCNIP4 Kv channel interacting protein 4 1.15218
TWF1 twinfilin actin binding protein 1 1.15116
ALG8 ALG8, alpha-1,3-glucosyltransferase 1.14684
HIST2H2BA histone cluster 2, H2ba (pseudogene) 1.14675
ZNF57 zinc finger protein 57 1.14662
OR5AU1 olfactory receptor, family 5, subfamily AU, member 1 1.14417
PSKH2 protein serine kinase H2 1.14244
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 1.13843
CXCR6 chemokine (C-X-C motif) receptor 6 1.13591
AXL AXL receptor tyrosine kinase 1.13456
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 1.12642
ZNF628 zinc finger protein 628 1.12616
ILK integrin-linked kinase 1.11541
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 1.11503
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) 1.11391
QDPR quinoid dihydropteridine reductase 1.11366
PCDHA10 protocadherin alpha 10 1.11034
THRAP3 thyroid hormone receptor associated protein 3 1.10518
ZNF611 zinc finger protein 611 1.10395
FGD1 FYVE, RhoGEF and PH domain containing 1 1.10036
RGS18 regulator of G-protein signaling 18 1.10011
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 1.09924
ACVR1 activin A receptor, type I 1.09904
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 1.09687
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 1.08944
NR1H4 nuclear receptor subfamily 1, group H, member 4 1.08875
IGF2R insulin-like growth factor 2 receptor 1.08745
SIX6 SIX homeobox 6 1.087
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 1.08554
RHCE Rh blood group, CcEe antigens 1.08395
SLC35F2 solute carrier family 35, member F2 1.08166
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 1.07892
SLC16A14 solute carrier family 16, member 14 1.07494
DNAH5 dynein, axonemal, heavy chain 5 1.07342
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 1.07295
H2BFM H2B histone family, member M 1.06634
FGG fibrinogen gamma chain 1.06406
NKIRAS2 NFKB inhibitor interacting Ras-like 2 1.06325
BCAP29 B-cell receptor-associated protein 29 1.05604
LSAMP limbic system-associated membrane protein 1.05472
UBE2E3 ubiquitin-conjugating enzyme E2E 3 1.05351
DHFR dihydrofolate reductase 1.05329
HDAC10 histone deacetylase 10 1.0462
ARF5 ADP-ribosylation factor 5 1.04595
SMAD5 SMAD family member 5 1.04561
AQP3 aquaporin 3 (Gill blood group) 1.04544
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 1.04329
ALX4 ALX homeobox 4 1.04085
SPINK1 serine peptidase inhibitor, Kazal type 1 1.03916
PRKG1 protein kinase, cGMP-dependent, type I 1.0379
RIN2 Ras and Rab interactor 2 1.03736
AP3M2 adaptor-related protein complex 3, mu 2 subunit 1.03686
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.03483
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 1.03355
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 1.03326
FRAS1 Fraser extracellular matrix complex subunit 1 1.03207
BAZ1B bromodomain adjacent to zinc finger domain, 1B 1.03185
PGAM1 phosphoglycerate mutase 1 (brain) 1.03085
NME5 NME/NM23 family member 5 1.02712
SEPT3 septin 3 1.02672
TRIM45 tripartite motif containing 45 1.02281
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.02215
OSTM1 osteopetrosis associated transmembrane protein 1 1.02044
TAS1R2 taste receptor, type 1, member 2 1.01438
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 1.01387
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 1.01355
TNIP1 TNFAIP3 interacting protein 1 1.01302
NFX1 nuclear transcription factor, X-box binding 1 1.00981
IL1RAP interleukin 1 receptor accessory protein 1.00964
SGPL1 sphingosine-1-phosphate lyase 1 1.00746
SSX1 synovial sarcoma, X breakpoint 1 1.00645
NIN ninein (GSK3B interacting protein) 1.00569
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.00448
GOLGA4 golgin A4 1.00173
ERCC8 excision repair cross-complementation group 8 1.00134
FOXD1 forkhead box D1 1.00084
STK32A serine/threonine kinase 32A 1.00026

decreased fitness

Symbol Name Standardized Value
RING1 ring finger protein 1 -3.57462
KIF17 kinesin family member 17 -3.48217
PRPF4B pre-mRNA processing factor 4B -3.30497
MAN2B1 mannosidase, alpha, class 2B, member 1 -3.14354
MEN1 multiple endocrine neoplasia I -3.1421
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -3.0886
KLK4 kallikrein-related peptidase 4 -3.05607
RAB22A RAB22A, member RAS oncogene family -3.00749
IGF1R insulin-like growth factor 1 receptor -2.9929
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -2.9614
CLCNKB chloride channel, voltage-sensitive Kb -2.93286
HYOU1 hypoxia up-regulated 1 -2.87462
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.78535
MCM5 minichromosome maintenance complex component 5 -2.77409
PCDHB10 protocadherin beta 10 -2.73735
GATA6 GATA binding protein 6 -2.72382
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -2.68339
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -2.67745
TWISTNB TWIST neighbor -2.64439
CAPSL calcyphosine-like -2.61004
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha -2.58705
WNT5A wingless-type MMTV integration site family, member 5A -2.57767
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -2.55508
PPP1R16B protein phosphatase 1, regulatory subunit 16B -2.5315
ZNF689 zinc finger protein 689 -2.52306
PA2G4 proliferation-associated 2G4, 38kDa -2.51758
RPP40 ribonuclease P/MRP 40kDa subunit -2.506
TLE3 transducin-like enhancer of split 3 -2.49584
COPE coatomer protein complex, subunit epsilon -2.48982
TRUB2 TruB pseudouridine (psi) synthase family member 2 -2.48663
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion -2.46946
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.46128
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.45299
CENPA centromere protein A -2.44615
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) -2.40748
DKC1 dyskeratosis congenita 1, dyskerin -2.40036
MCM2 minichromosome maintenance complex component 2 -2.35887
UBE2D3 ubiquitin-conjugating enzyme E2D 3 -2.35222
GAP43 growth associated protein 43 -2.34503
C19ORF48 chromosome 19 open reading frame 48 -2.33393
MED12 mediator complex subunit 12 -2.32312
RHBDD3 rhomboid domain containing 3 -2.30662
RPS15A ribosomal protein S15a -2.28666
CDK9 cyclin-dependent kinase 9 -2.27987
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.2659
TTK TTK protein kinase -2.24433
C1RL complement component 1, r subcomponent-like -2.22881
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -2.22464
POLR2F polymerase (RNA) II (DNA directed) polypeptide F -2.21987
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -2.21581
RPA2 replication protein A2, 32kDa -2.18548
KRAS Kirsten rat sarcoma viral oncogene homolog -2.17462
RABGGTA Rab geranylgeranyltransferase, alpha subunit -2.16596
PRDM11 PR domain containing 11 -2.16388
CSNK1A1 casein kinase 1, alpha 1 -2.16078
CENPF centromere protein F, 350/400kDa -2.15625
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae) -2.14982
NUB1 negative regulator of ubiquitin-like proteins 1 -2.14145
ALYREF Aly/REF export factor -2.14089
LIG1 ligase I, DNA, ATP-dependent -2.12861
KRT73 keratin 73, type II -2.12445
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -2.12231
NFRKB nuclear factor related to kappaB binding protein -2.11044
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 -2.10928
MEX3B mex-3 RNA binding family member B -2.10588
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -2.09331
STX4 syntaxin 4 -2.08971
CCND1 cyclin D1 -2.07925
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -2.07193
ADHFE1 alcohol dehydrogenase, iron containing, 1 -2.06597
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 -2.03711
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide -2.02652
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 -2.0147
HARS2 histidyl-tRNA synthetase 2, mitochondrial -1.99101
PDCD6IP programmed cell death 6 interacting protein -1.96335
NME1-NME2 NME1-NME2 readthrough -1.96089
SIN3B SIN3 transcription regulator family member B -1.94307
PDILT protein disulfide isomerase-like, testis expressed -1.93519
HMGB2 high mobility group box 2 -1.93323
HOXA13 homeobox A13 -1.9279
BIRC6 baculoviral IAP repeat containing 6 -1.91927
SAFB scaffold attachment factor B -1.91779
PRPF18 pre-mRNA processing factor 18 -1.91734
MOB3A MOB kinase activator 3A -1.91228
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -1.90236
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -1.90012
TPMT thiopurine S-methyltransferase -1.89556
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) -1.88379
HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 -1.87606
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -1.87268
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -1.86593
PIAS3 protein inhibitor of activated STAT, 3 -1.86424
FOXA1 forkhead box A1 -1.86109
ZFX zinc finger protein, X-linked -1.8558
ZNF473 zinc finger protein 473 -1.85461
APC adenomatous polyposis coli -1.85431
FGFR3 fibroblast growth factor receptor 3 -1.85175
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -1.84898
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein -1.84508
ADSL adenylosuccinate lyase -1.82283
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -1.81342
AKAP14 A kinase (PRKA) anchor protein 14 -1.80551
UBE2F ubiquitin-conjugating enzyme E2F (putative) -1.79884
FBXL19 F-box and leucine-rich repeat protein 19 -1.794
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) -1.78461
FOXB1 forkhead box B1 -1.77718
SRRM1 serine/arginine repetitive matrix 1 -1.772
CDK6 cyclin-dependent kinase 6 -1.76151
ADIPOR1 adiponectin receptor 1 -1.75528
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 -1.74541
STK17B serine/threonine kinase 17b -1.74061
IL9R interleukin 9 receptor -1.73994
MDM4 MDM4, p53 regulator -1.7386
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -1.7384
TEAD2 TEA domain family member 2 -1.73438
ACO2 aconitase 2, mitochondrial -1.72996
MYH9 myosin, heavy chain 9, non-muscle -1.71906
TM7SF2 transmembrane 7 superfamily member 2 -1.71881
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -1.71779
PMPCA peptidase (mitochondrial processing) alpha -1.71778
RGS19 regulator of G-protein signaling 19 -1.71042
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) -1.70377
NQO1 NAD(P)H dehydrogenase, quinone 1 -1.70198
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -1.69872
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.69543
ADPRHL1 ADP-ribosylhydrolase like 1 -1.68811
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa -1.68381
UQCRC2 ubiquinol-cytochrome c reductase core protein II -1.68229
LIPM lipase, family member M -1.67378
TRA2A transformer 2 alpha homolog (Drosophila) -1.67301
NEIL2 nei endonuclease VIII-like 2 (E. coli) -1.66803
RWDD2A RWD domain containing 2A -1.66636
HNRNPK heterogeneous nuclear ribonucleoprotein K -1.66308
TPR translocated promoter region, nuclear basket protein -1.65977
MOS v-mos Moloney murine sarcoma viral oncogene homolog -1.65826
TMED2 transmembrane emp24 domain trafficking protein 2 -1.65447
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) -1.64025
PLK3 polo-like kinase 3 -1.63834
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma -1.63801
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa -1.63305
TSG101 tumor susceptibility 101 -1.62504
HECTD2 HECT domain containing E3 ubiquitin protein ligase 2 -1.62228
ZNF781 zinc finger protein 781 -1.62113
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -1.61904
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -1.61539
HOXC13 homeobox C13 -1.61434
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -1.61142
GRAP2 GRB2-related adaptor protein 2 -1.60593
RBM10 RNA binding motif protein 10 -1.6029
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 -1.60008
AXIN2 axin 2 -1.5989
OLFML2B olfactomedin-like 2B -1.59727
AFG3L1P AFG3-like AAA ATPase 1, pseudogene -1.59687
ZNF721 zinc finger protein 721 -1.59655
MUL1 mitochondrial E3 ubiquitin protein ligase 1 -1.59484
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase -1.59114
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -1.58801
TAS2R1 taste receptor, type 2, member 1 -1.58788
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa -1.58757
KDM4C lysine (K)-specific demethylase 4C -1.58463
CSNK2B casein kinase 2, beta polypeptide -1.58354
ZNF436 zinc finger protein 436 -1.57406
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -1.56565
PER2 period circadian clock 2 -1.55526
AKT1 v-akt murine thymoma viral oncogene homolog 1 -1.55092
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) -1.54377
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 -1.54173
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) -1.53846
ECE1 endothelin converting enzyme 1 -1.53762
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -1.53616
TRAPPC8 trafficking protein particle complex 8 -1.53195
WNT10B wingless-type MMTV integration site family, member 10B -1.52829
HIATL1 hippocampus abundant transcript-like 1 -1.52717
GARS glycyl-tRNA synthetase -1.52269
HIST3H3 histone cluster 3, H3 -1.52249
SYT15 synaptotagmin XV -1.52152
MAP3K11 mitogen-activated protein kinase kinase kinase 11 -1.52089
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -1.51918
PAX9 paired box 9 -1.51902
NXF1 nuclear RNA export factor 1 -1.50193
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -1.49744
RPS18 ribosomal protein S18 -1.4959
GTF2A1 general transcription factor IIA, 1, 19/37kDa -1.49143
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -1.49076
GCKR glucokinase (hexokinase 4) regulator -1.48479
SSTR1 somatostatin receptor 1 -1.4846
SLC30A7 solute carrier family 30 (zinc transporter), member 7 -1.48108
MAT2B methionine adenosyltransferase II, beta -1.47932
SMS spermine synthase -1.47674
MED19 mediator complex subunit 19 -1.47538
HOXC5 homeobox C5 -1.47369
PIM1 Pim-1 proto-oncogene, serine/threonine kinase -1.47327
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -1.47219
IL31RA interleukin 31 receptor A -1.47063
PCDHGA2 protocadherin gamma subfamily A, 2 -1.46798
FER fer (fps/fes related) tyrosine kinase -1.46469
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -1.46459
CKM creatine kinase, muscle -1.46418
NCOA3 nuclear receptor coactivator 3 -1.46349
PHF5A PHD finger protein 5A -1.46307
REPIN1 replication initiator 1 -1.46128
IQGAP1 IQ motif containing GTPase activating protein 1 -1.4597
ZNF174 zinc finger protein 174 -1.45654
FABP1 fatty acid binding protein 1, liver -1.45387
LRRK2 leucine-rich repeat kinase 2 -1.45216
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -1.44782
GDF2 growth differentiation factor 2 -1.44391
LRPPRC leucine-rich pentatricopeptide repeat containing -1.4415
RBM47 RNA binding motif protein 47 -1.44127
CAPZB capping protein (actin filament) muscle Z-line, beta -1.43619
BCCIP BRCA2 and CDKN1A interacting protein -1.4299
NOD2 nucleotide-binding oligomerization domain containing 2 -1.42586
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 -1.41778
ZNF81 zinc finger protein 81 -1.41679
CTNNBL1 catenin, beta like 1 -1.41435
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -1.412
SLU7 SLU7 splicing factor homolog (S. cerevisiae) -1.41132
CHEK1 checkpoint kinase 1 -1.41054
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -1.40325
MYC v-myc avian myelocytomatosis viral oncogene homolog -1.39585
TPTE transmembrane phosphatase with tensin homology -1.39293
GPN3 GPN-loop GTPase 3 -1.38911
POU2F2 POU class 2 homeobox 2 -1.38853
GLS glutaminase -1.38234
POC1A POC1 centriolar protein A -1.37999
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa -1.3798
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa -1.37911
ZNF462 zinc finger protein 462 -1.3763
RAB6B RAB6B, member RAS oncogene family -1.37299
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -1.37143
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 -1.3693
ARID3A AT rich interactive domain 3A (BRIGHT-like) -1.36701
DPYS dihydropyrimidinase -1.3635
KLF6 Kruppel-like factor 6 -1.36304
LRFN1 leucine rich repeat and fibronectin type III domain containing 1 -1.36144
CUL3 cullin 3 -1.36132
POR P450 (cytochrome) oxidoreductase -1.35675
FBXW11 F-box and WD repeat domain containing 11 -1.35421
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae) -1.35121
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -1.34871
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.34843
ARPC4-TTLL3 ARPC4-TTLL3 readthrough -1.33934
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) -1.3378
SSB Sjogren syndrome antigen B (autoantigen La) -1.33109
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 -1.33099
RAN RAN, member RAS oncogene family -1.3265
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 -1.32376
MAPK1 mitogen-activated protein kinase 1 -1.32112
HAND2 heart and neural crest derivatives expressed 2 -1.31896
L3MBTL4 l(3)mbt-like 4 (Drosophila) -1.31415
MED20 mediator complex subunit 20 -1.31251
PRPF3 pre-mRNA processing factor 3 -1.3125
SAMD4B sterile alpha motif domain containing 4B -1.31232
AMDHD2 amidohydrolase domain containing 2 -1.3072
UBR1 ubiquitin protein ligase E3 component n-recognin 1 -1.30538
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa -1.30523
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 -1.30029
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -1.29914
APOM apolipoprotein M -1.29371
EPB41L1 erythrocyte membrane protein band 4.1-like 1 -1.29233
EXOSC9 exosome component 9 -1.29041
AKAP9 A kinase (PRKA) anchor protein 9 -1.28929
NUP214 nucleoporin 214kDa -1.28868
CCNI cyclin I -1.28824
TADA3 transcriptional adaptor 3 -1.28652
OIP5 Opa interacting protein 5 -1.27938
ZIK1 zinc finger protein interacting with K protein 1 -1.27771
BCL2L1 BCL2-like 1 -1.27676
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit -1.27608
RBMX RNA binding motif protein, X-linked -1.27492
TACC3 transforming, acidic coiled-coil containing protein 3 -1.27134
CARD9 caspase recruitment domain family, member 9 -1.26913
VARS valyl-tRNA synthetase -1.2675
CX3CR1 chemokine (C-X3-C motif) receptor 1 -1.26746
LARS leucyl-tRNA synthetase -1.26498
RREB1 ras responsive element binding protein 1 -1.25758
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 -1.25686
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -1.25638
RNPS1 RNA binding protein S1, serine-rich domain -1.25261
SF3B1 splicing factor 3b, subunit 1, 155kDa -1.25208
NCBP2 nuclear cap binding protein subunit 2, 20kDa -1.25051
TAS2R60 taste receptor, type 2, member 60 -1.24935
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -1.24794
ARNT aryl hydrocarbon receptor nuclear translocator -1.2471
EIF3F eukaryotic translation initiation factor 3, subunit F -1.24597
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) -1.24489
RNF40 ring finger protein 40, E3 ubiquitin protein ligase -1.24482
HIST3H2A histone cluster 3, H2a -1.23689
BRAF B-Raf proto-oncogene, serine/threonine kinase -1.23618
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -1.23587
TNPO2 transportin 2 -1.23579
MCHR2 melanin-concentrating hormone receptor 2 -1.23371
HIST1H3A histone cluster 1, H3a -1.23282
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -1.23175
KDM2A lysine (K)-specific demethylase 2A -1.22942
TSSK3 testis-specific serine kinase 3 -1.22606
NRTN neurturin -1.22602
USO1 USO1 vesicle transport factor -1.2259
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 -1.22338
GRHL2 grainyhead-like 2 (Drosophila) -1.21957
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -1.21234
ZNF787 zinc finger protein 787 -1.21082
SMC2 structural maintenance of chromosomes 2 -1.21004
SPPL2A signal peptide peptidase like 2A -1.20736
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -1.20688
UQCRC1 ubiquinol-cytochrome c reductase core protein I -1.2067
IL7R interleukin 7 receptor -1.20586
LHX8 LIM homeobox 8 -1.20194
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 -1.20141
TRRAP transformation/transcription domain-associated protein -1.20137
ZNF236 zinc finger protein 236 -1.20129
RPS3 ribosomal protein S3 -1.20089
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 -1.19872
KDM1A lysine (K)-specific demethylase 1A -1.19606
RAB1B RAB1B, member RAS oncogene family -1.19459
YBX1 Y box binding protein 1 -1.19439
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -1.19085
TXNL4A thioredoxin-like 4A -1.18906
CCDC71 coiled-coil domain containing 71 -1.18812
RHOT1 ras homolog family member T1 -1.18692
SKI SKI proto-oncogene -1.18585
TUBD1 tubulin, delta 1 -1.18555
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -1.1852
TARDBP TAR DNA binding protein -1.18456
NUP153 nucleoporin 153kDa -1.18179
LIMD1 LIM domains containing 1 -1.18035
PREB prolactin regulatory element binding -1.17602
SFSWAP splicing factor, suppressor of white-apricot family -1.17416
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -1.17254
ZC3H18 zinc finger CCCH-type containing 18 -1.17217
EIF3G eukaryotic translation initiation factor 3, subunit G -1.17053
ZNF93 zinc finger protein 93 -1.17016
MED4 mediator complex subunit 4 -1.16924
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -1.16706
CD59 CD59 molecule, complement regulatory protein -1.16594
JMJD7-PLA2G4B JMJD7-PLA2G4B readthrough -1.16553
PAN2 PAN2 poly(A) specific ribonuclease subunit -1.16453
RBMXL1 RNA binding motif protein, X-linked-like 1 -1.16332
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa -1.16307
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -1.16143
RPS15 ribosomal protein S15 -1.16
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 -1.15849
CAB39 calcium binding protein 39 -1.15692
HPGDS hematopoietic prostaglandin D synthase -1.15597
EPS15 epidermal growth factor receptor pathway substrate 15 -1.15538
MYEF2 myelin expression factor 2 -1.15346
C10ORF10 chromosome 10 open reading frame 10 -1.15321
FXYD7 FXYD domain containing ion transport regulator 7 -1.15267
RHOV ras homolog family member V -1.15223
IMPG2 interphotoreceptor matrix proteoglycan 2 -1.15049
EVX1 even-skipped homeobox 1 -1.14955
RNMT RNA (guanine-7-) methyltransferase -1.14655
ZNF200 zinc finger protein 200 -1.14581
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa -1.14447
RPP38 ribonuclease P/MRP 38kDa subunit -1.14331
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) -1.14286
FAF2 Fas associated factor family member 2 -1.14251
ZFR zinc finger RNA binding protein -1.14145
HIST1H2BJ histone cluster 1, H2bj -1.14033
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -1.13572
GATA4 GATA binding protein 4 -1.13519
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 -1.13361
ARG1 arginase 1 -1.13279
DCP1B decapping mRNA 1B -1.13259
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -1.13141
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) -1.13138
EFNA3 ephrin-A3 -1.1311
CYC1 cytochrome c-1 -1.12676
CCNA2 cyclin A2 -1.12443
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) -1.12422
WDR33 WD repeat domain 33 -1.12392
TUBG1 tubulin, gamma 1 -1.1232
SMC1A structural maintenance of chromosomes 1A -1.12257
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -1.12053
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -1.11864
APOA2 apolipoprotein A-II -1.11739
CDK13 cyclin-dependent kinase 13 -1.11699
ZNF432 zinc finger protein 432 -1.11635
LOC100653162 -1.11578
NPEPPS aminopeptidase puromycin sensitive -1.11413
ZNF579 zinc finger protein 579 -1.11264
LRP1B low density lipoprotein receptor-related protein 1B -1.11002
HNF1B HNF1 homeobox B -1.10961
WBP11 WW domain binding protein 11 -1.10831
CARS cysteinyl-tRNA synthetase -1.10802
CAMK4 calcium/calmodulin-dependent protein kinase IV -1.10729
PRPF8 pre-mRNA processing factor 8 -1.10728
TLR4 toll-like receptor 4 -1.10674
GRIK3 glutamate receptor, ionotropic, kainate 3 -1.10637
AGAP5 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 -1.10584
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) -1.10154
RAB40B RAB40B, member RAS oncogene family -1.09992
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -1.09855
SSRP1 structure specific recognition protein 1 -1.09657
CAPN9 calpain 9 -1.09613
UBL4A ubiquitin-like 4A -1.09583
PSIP1 PC4 and SFRS1 interacting protein 1 -1.09081
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa -1.08385
MIB2 mindbomb E3 ubiquitin protein ligase 2 -1.08366
DNASE1L2 deoxyribonuclease I-like 2 -1.08125
LRP11 low density lipoprotein receptor-related protein 11 -1.0794
ICOS inducible T-cell co-stimulator -1.07908
TUSC1 tumor suppressor candidate 1 -1.07895
SLCO1B7 solute carrier organic anion transporter family, member 1B7 (non-functional) -1.07765
FAM207A family with sequence similarity 207, member A -1.07678
RBM17 RNA binding motif protein 17 -1.07655
WFDC5 WAP four-disulfide core domain 5 -1.07363
GRB10 growth factor receptor-bound protein 10 -1.06971
SEPHS1 selenophosphate synthetase 1 -1.0696
FPR3 formyl peptide receptor 3 -1.06442
BMP2 bone morphogenetic protein 2 -1.06282
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -1.06253
M6PR mannose-6-phosphate receptor (cation dependent) -1.06188
ZMIZ1 zinc finger, MIZ-type containing 1 -1.06178
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -1.06175
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1 -1.05966
TSC22D3 TSC22 domain family, member 3 -1.05719
HDAC1 histone deacetylase 1 -1.0554
GSR glutathione reductase -1.05383
RAX retina and anterior neural fold homeobox -1.05344
RNF25 ring finger protein 25 -1.05176
PC pyruvate carboxylase -1.04896
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -1.04788
SRRM2 serine/arginine repetitive matrix 2 -1.04603
FURIN furin (paired basic amino acid cleaving enzyme) -1.04585
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide -1.04572
CPB1 carboxypeptidase B1 (tissue) -1.04516
FAM13A family with sequence similarity 13, member A -1.04451
CDC37 cell division cycle 37 -1.04447
TTF2 transcription termination factor, RNA polymerase II -1.04393
RPS3A ribosomal protein S3A -1.04268
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -1.03977
CALML4 calmodulin-like 4 -1.03854
MET MET proto-oncogene, receptor tyrosine kinase -1.03811
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 -1.03578
SDK1 sidekick cell adhesion molecule 1 -1.03536
TRIM54 tripartite motif containing 54 -1.03513
GCH1 GTP cyclohydrolase 1 -1.03363
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -1.03273
HCK HCK proto-oncogene, Src family tyrosine kinase -1.03134
CNKSR2 connector enhancer of kinase suppressor of Ras 2 -1.03094
TOP2A topoisomerase (DNA) II alpha 170kDa -1.02959
HOXA9 homeobox A9 -1.02805
IL17RC interleukin 17 receptor C -1.02569
TSHZ2 teashirt zinc finger homeobox 2 -1.02452
ZNF143 zinc finger protein 143 -1.02414
MTOR mechanistic target of rapamycin (serine/threonine kinase) -1.02132
CCNG1 cyclin G1 -1.02111
CAMKV CaM kinase-like vesicle-associated -1.0204
PFN1 profilin 1 -1.01869
RFC4 replication factor C (activator 1) 4, 37kDa -1.01813
RPS17 ribosomal protein S17 -1.01672
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 -1.01485
DMAP1 DNA methyltransferase 1 associated protein 1 -1.0129
RPL6 ribosomal protein L6 -1.01275
KCTD7 potassium channel tetramerization domain containing 7 -1.01264
THADA thyroid adenoma associated -1.01176
RAB3A RAB3A, member RAS oncogene family -1.01113
PRSS36 protease, serine, 36 -1.01106
SIRT2 sirtuin 2 -1.00956
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 -1.00955
LIPH lipase, member H -1.00891
ZNF207 zinc finger protein 207 -1.00614
MYB v-myb avian myeloblastosis viral oncogene homolog -1.00542
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 -1.00491
OVCA2 ovarian tumor suppressor candidate 2 -1.0046
SYNJ2 synaptojanin 2 -1.0033
ZNF358 zinc finger protein 358 -1.00328