| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | S-phase kinase-associated protein 1|This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6500) |
| External Link | https://ncbi.nlm.nih.gov/gene/6500 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the SKP1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0149119 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0134178 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.0133475 |
| KRT19 | keratin 19, type I | 0.0130428 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.0128784 |
| ARG2 | arginase 2 | 0.0121993 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0114423 |
| MAGEA3 | melanoma antigen family A3 | 0.0113947 |
| S100A8 | S100 calcium binding protein A8 | 0.0113503 |
| PXDN | peroxidasin | 0.0112821 |
| PERP | PERP, TP53 apoptosis effector | 0.0110693 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.01097 |
| GNAS | GNAS complex locus | 0.0103946 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0102793 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0101199 |
| ANXA3 | annexin A3 | 0.0101128 |
| GLS | glutaminase | 0.0100841 |
| RAB25 | RAB25, member RAS oncogene family | 0.0100082 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00989731 |
| TSPYL5 | TSPY-like 5 | 0.00988229 |
| MYO1B | myosin IB | 0.00987227 |
| SYNGR3 | synaptogyrin 3 | 0.00974577 |
| FHL1 | four and a half LIM domains 1 | 0.00966729 |
| CD200 | CD200 molecule | 0.00966632 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00947266 |
| SQLE | squalene epoxidase | 0.0093981 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.00927726 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | 0.00917789 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00913918 |
| CLIC3 | chloride intracellular channel 3 | 0.00893292 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00867766 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00850152 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00847333 |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.00844453 |
| DBN1 | drebrin 1 | 0.0083868 |
| REEP1 | receptor accessory protein 1 | 0.00838279 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00836731 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00835485 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00834868 |
| NPY | neuropeptide Y | 0.00831338 |
| CENPE | centromere protein E, 312kDa | 0.00826393 |
| CST6 | cystatin E/M | 0.00821162 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00818886 |
| LTF | lactotransferrin | 0.00818517 |
| FILIP1L | filamin A interacting protein 1-like | 0.00811015 |
| EPCAM | epithelial cell adhesion molecule | 0.00808381 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00806172 |
| ATP5MG | ATP synthase membrane subunit g | 0.00801457 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00796238 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00792403 |
| MLXIP | MLX interacting protein | 0.00786725 |
| STK38 | serine/threonine kinase 38 | 0.00783619 |
| STK32B | serine/threonine kinase 32B | 0.00781272 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00776927 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.00771669 |
| MYO6 | myosin VI | 0.00769095 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00764164 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00763523 |
| ITGA6 | integrin, alpha 6 | 0.00759761 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.00758377 |
| LRRC15 | leucine rich repeat containing 15 | 0.00753766 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00753155 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00747162 |
| CAST | calpastatin | 0.00740405 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00735586 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00727476 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.00725697 |
| REXO2 | RNA exonuclease 2 | 0.00719631 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.0071906 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00717932 |
| MYBPC1 | myosin binding protein C, slow type | 0.0071757 |
| MAGEA12 | melanoma antigen family A12 | 0.00716982 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00713756 |
| SPPL2B | signal peptide peptidase like 2B | 0.00708848 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00707706 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.00704933 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | 0.00703636 |
| GATA3 | GATA binding protein 3 | 0.0070302 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00686738 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.0068593 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00683721 |
| FHOD3 | formin homology 2 domain containing 3 | 0.00681899 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.00676381 |
| ECT2 | epithelial cell transforming 2 | 0.00676147 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.00675026 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00673195 |
| TCAF1 | TRPM8 channel-associated factor 1 | 0.0067193 |
| CA2 | carbonic anhydrase II | 0.00671817 |
| PRRX1 | paired related homeobox 1 | 0.0066769 |
| LAT2 | linker for activation of T cells family, member 2 | 0.0066589 |
| CHI3L2 | chitinase 3-like 2 | 0.00665551 |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa | 0.00665359 |
| SCEL | sciellin | 0.00663193 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.0066247 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 | 0.00662171 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.006604 |
| XIC | X chromosome inactivation center | 0.0065994 |
| RND3 | Rho family GTPase 3 | 0.00657981 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00657504 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00657468 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0065604 |
| PRSS8 | protease, serine, 8 | 0.00653296 |
| CTSH | cathepsin H | 0.00650424 |
| STX3 | syntaxin 3 | 0.00649592 |
| MOB4 | MOB family member 4, phocein | 0.00648938 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00643724 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00642263 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00639013 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.006369 |
| CAV2 | caveolin 2 | 0.00636624 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.00633911 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00631696 |
| YBX1 | Y box binding protein 1 | 0.00628252 |
| TTN | titin | 0.00628181 |
| DES | desmin | 0.00627901 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.0062711 |
| VGF | VGF nerve growth factor inducible | 0.00625287 |
| NOX4 | NADPH oxidase 4 | 0.00623677 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | 0.00623005 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00622973 |
| GPSM2 | G-protein signaling modulator 2 | 0.00621185 |
| RRM2 | ribonucleotide reductase M2 | 0.00617802 |
| STAG3 | stromal antigen 3 | 0.00616954 |
| SFTPD | surfactant protein D | 0.00616722 |
| FDX1 | ferredoxin 1 | 0.00614341 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00614205 |
| TMEM243 | transmembrane protein 243, mitochondrial | 0.00613087 |
| NDNF | neuron-derived neurotrophic factor | 0.00612268 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00610764 |
| KRT7 | keratin 7, type II | 0.00610372 |
| MANSC1 | MANSC domain containing 1 | 0.00610247 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | 0.00609412 |
| DENND1B | DENN/MADD domain containing 1B | 0.00609324 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00608715 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00607598 |
| EMP2 | epithelial membrane protein 2 | 0.00603384 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.0060155 |
| MMP7 | matrix metallopeptidase 7 | 0.00599447 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | 0.00598157 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00598073 |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 | 0.00597652 |
| NEK7 | NIMA-related kinase 7 | 0.00596391 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00595937 |
| MFAP5 | microfibrillar associated protein 5 | 0.00594149 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0059283 |
| PROM1 | prominin 1 | 0.00591376 |
| PAM | peptidylglycine alpha-amidating monooxygenase | 0.00589113 |
| DCHS1 | dachsous cadherin-related 1 | 0.00588815 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.00588375 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.00588369 |
| PPL | periplakin | 0.00587617 |
| KRCC1 | lysine-rich coiled-coil 1 | 0.00587443 |
| NOP10 | NOP10 ribonucleoprotein | 0.00586768 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00586529 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00585933 |
| S100A14 | S100 calcium binding protein A14 | 0.0058311 |
| GSPT2 | G1 to S phase transition 2 | 0.005827 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00582552 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.00582103 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | 0.00581351 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00580179 |
| LAMC2 | laminin, gamma 2 | 0.00579939 |
| IL27RA | interleukin 27 receptor, alpha | 0.00577629 |
| STK39 | serine threonine kinase 39 | 0.00577472 |
| BICD2 | bicaudal D homolog 2 (Drosophila) | 0.00575847 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00575769 |
| CD46 | CD46 molecule, complement regulatory protein | 0.00574959 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | 0.00574075 |
| LDLR | low density lipoprotein receptor | 0.00570971 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.00570743 |
| RUFY2 | RUN and FYVE domain containing 2 | 0.00570528 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00569867 |
| TGFA | transforming growth factor, alpha | 0.00568683 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | 0.00567309 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.00566697 |
| CLDN4 | claudin 4 | 0.00564202 |
| PAX5 | paired box 5 | 0.00564062 |
| IL32 | interleukin 32 | 0.0056399 |
| CLIC1 | chloride intracellular channel 1 | 0.0056311 |
| ITSN2 | intersectin 2 | 0.00562756 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00561673 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.00561121 |
| SMAGP | small cell adhesion glycoprotein | 0.00560871 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00560109 |
| KIF13B | kinesin family member 13B | 0.00559546 |
| MLF1 | myeloid leukemia factor 1 | 0.00559434 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 0.00556164 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.00551603 |
| PSG5 | pregnancy specific beta-1-glycoprotein 5 | 0.00551527 |
| POU4F1 | POU class 4 homeobox 1 | 0.00550342 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 0.00549798 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | 0.00549179 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00548991 |
| TNS1 | tensin 1 | 0.00547888 |
| CLDN1 | claudin 1 | 0.00547595 |
| LARP4 | La ribonucleoprotein domain family, member 4 | 0.00546865 |
| ISL1 | ISL LIM homeobox 1 | 0.0054681 |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) | 0.00545825 |
| ETNK1 | ethanolamine kinase 1 | 0.00545814 |
| USP15 | ubiquitin specific peptidase 15 | 0.00545786 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00545566 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.00545225 |
| TPTE | transmembrane phosphatase with tensin homology | 0.00542549 |
| SOCS2 | suppressor of cytokine signaling 2 | 0.00541859 |
| GSPT1 | G1 to S phase transition 1 | 0.00541693 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 0.00541202 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.00539492 |
| VLDLR | very low density lipoprotein receptor | 0.00538578 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.00537542 |
| MYD88 | myeloid differentiation primary response 88 | 0.0053733 |
| TRIB3 | tribbles pseudokinase 3 | 0.00535335 |
| FAM50A | family with sequence similarity 50, member A | 0.00534656 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | 0.0053446 |
| HLA-B | major histocompatibility complex, class I, B | 0.0053418 |
| NINL | ninein-like | 0.00534142 |
| FMO5 | flavin containing monooxygenase 5 | 0.00533333 |
| RUBCN | rubicon autophagy regulator | 0.00533277 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0053302 |
| VANGL1 | VANGL planar cell polarity protein 1 | 0.00532789 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00532114 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00531719 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00531321 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | 0.00530862 |
| CKM | creatine kinase, muscle | 0.00530215 |
| KRT15 | keratin 15, type I | 0.005297 |
| PLBD1 | phospholipase B domain containing 1 | 0.00529315 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.00528781 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.00528245 |
| RNASET2 | ribonuclease T2 | 0.0052635 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.00525931 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00525285 |
| CCDC90B | coiled-coil domain containing 90B | 0.00524928 |
| SIRT3 | sirtuin 3 | 0.00524717 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00524332 |
| MSX1 | msh homeobox 1 | 0.00523338 |
| SPRR1B | small proline-rich protein 1B | 0.00523098 |
| MFN1 | mitofusin 1 | 0.00522562 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | 0.00522383 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.00520959 |
| MYO1D | myosin ID | 0.00519574 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00518701 |
| PRC1 | protein regulator of cytokinesis 1 | 0.00517099 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00516909 |
| DLAT | dihydrolipoamide S-acetyltransferase | 0.00514362 |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) | 0.00514103 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.00514011 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 0.0051391 |
| MFSD6 | major facilitator superfamily domain containing 6 | 0.005134 |
| MALL | mal, T-cell differentiation protein-like | 0.00513389 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SKP1 | S-phase kinase-associated protein 1 | -0.0400615 |
| CLU | clusterin | -0.0150337 |
| GPM6B | glycoprotein M6B | -0.0135514 |
| CP | ceruloplasmin (ferroxidase) | -0.0134241 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0129537 |
| RGCC | regulator of cell cycle | -0.0129415 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0121358 |
| PLP1 | proteolipid protein 1 | -0.0117202 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0116528 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.0115677 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0114412 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0112173 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0109223 |
| WT1 | Wilms tumor 1 | -0.0108692 |
| TUBB2A | tubulin, beta 2A class IIa | -0.0107589 |
| CFD | complement factor D (adipsin) | -0.0105059 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.0104977 |
| KLF9 | Kruppel-like factor 9 | -0.0104783 |
| OLFML2A | olfactomedin-like 2A | -0.0104426 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0101042 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00980889 |
| BBX | bobby sox homolog (Drosophila) | -0.00970348 |
| AOC1 | amine oxidase, copper containing 1 | -0.00964678 |
| GPX2 | glutathione peroxidase 2 | -0.00945141 |
| FAM107A | family with sequence similarity 107, member A | -0.00932057 |
| VWF | von Willebrand factor | -0.00931815 |
| NREP | neuronal regeneration related protein | -0.00916901 |
| MCAM | melanoma cell adhesion molecule | -0.00916214 |
| MT1X | metallothionein 1X | -0.0091619 |
| CFH | complement factor H | -0.00912826 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00910544 |
| FAM13B | family with sequence similarity 13, member B | -0.00904021 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.00900526 |
| PTN | pleiotrophin | -0.00896866 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.00896226 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00887352 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00882995 |
| IFI44L | interferon-induced protein 44-like | -0.00869744 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00867255 |
| SQSTM1 | sequestosome 1 | -0.00866116 |
| HNMT | histamine N-methyltransferase | -0.00860727 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.00859859 |
| PIR | pirin (iron-binding nuclear protein) | -0.00858164 |
| PEG3 | paternally expressed 3 | -0.00848536 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00847838 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00847452 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00844059 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00839978 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.00839528 |
| CAMLG | calcium modulating ligand | -0.00837023 |
| C8ORF33 | chromosome 8 open reading frame 33 | -0.00831748 |
| STAB1 | stabilin 1 | -0.0082743 |
| MARCKSL1 | MARCKS-like 1 | -0.00824884 |
| GPM6A | glycoprotein M6A | -0.00824277 |
| CD81 | CD81 molecule | -0.00816876 |
| IL7R | interleukin 7 receptor | -0.00815878 |
| LRRC17 | leucine rich repeat containing 17 | -0.00811652 |
| DIRAS2 | DIRAS family, GTP-binding RAS-like 2 | -0.00809477 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00804545 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00800411 |
| IRS2 | insulin receptor substrate 2 | -0.00792124 |
| MT1H | metallothionein 1H | -0.00782773 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.00778877 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00777895 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00774912 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.00773791 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.00773309 |
| ASPA | aspartoacylase | -0.00770895 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00762674 |
| PLIN1 | perilipin 1 | -0.00760629 |
| C5ORF15 | chromosome 5 open reading frame 15 | -0.00755412 |
| DUSP2 | dual specificity phosphatase 2 | -0.00754231 |
| LHFP | lipoma HMGIC fusion partner | -0.00752031 |
| GPX3 | glutathione peroxidase 3 | -0.00747905 |
| MT2A | metallothionein 2A | -0.0074517 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00745089 |
| CNTN1 | contactin 1 | -0.00741218 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00741077 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | -0.00736523 |
| SFPQ | splicing factor proline/glutamine-rich | -0.00732424 |
| SAP18 | Sin3A-associated protein, 18kDa | -0.00731434 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00723784 |
| CST7 | cystatin F (leukocystatin) | -0.00722349 |
| KAZN | kazrin, periplakin interacting protein | -0.00720549 |
| SEPTIN4 | septin 4 | -0.0072013 |
| PLTP | phospholipid transfer protein | -0.00719537 |
| NTS | neurotensin | -0.00715349 |
| MT1E | metallothionein 1E | -0.00714181 |
| HINT1 | histidine triad nucleotide binding protein 1 | -0.00713883 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | -0.00713516 |
| F8 | coagulation factor VIII, procoagulant component | -0.00713493 |
| ARL4A | ADP-ribosylation factor-like 4A | -0.00710695 |
| OSBPL1A | oxysterol binding protein-like 1A | -0.00710091 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.0070877 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00708219 |
| CDC42SE1 | CDC42 small effector 1 | -0.00708076 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.0070677 |
| SRSF5 | serine/arginine-rich splicing factor 5 | -0.00706288 |
| NRIP3 | nuclear receptor interacting protein 3 | -0.0070606 |
| CANX | calnexin | -0.00706038 |
| CIDEC | cell death-inducing DFFA-like effector c | -0.00704121 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | -0.00704074 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.0070221 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00701029 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00700983 |
| PMP22 | peripheral myelin protein 22 | -0.00696731 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0069591 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00691398 |
| SCG5 | secretogranin V | -0.00689079 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00686308 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00684606 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) | -0.00683073 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00680933 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.00680087 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00679419 |
| SLC16A6 | solute carrier family 16, member 6 | -0.00677779 |
| RASIP1 | Ras interacting protein 1 | -0.00671883 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00670679 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00668426 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00668053 |
| ING3 | inhibitor of growth family, member 3 | -0.0066755 |
| PFN2 | profilin 2 | -0.00665608 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -0.00665426 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00664394 |
| HAL | histidine ammonia-lyase | -0.0066434 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.00663313 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00662405 |
| CDC45 | cell division cycle 45 | -0.00661419 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | -0.00659615 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.0065816 |
| MT1F | metallothionein 1F | -0.00655163 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00654979 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.00653216 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00651898 |
| MGLL | monoglyceride lipase | -0.00651217 |
| SMAD5 | SMAD family member 5 | -0.00650658 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.00648677 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00646505 |
| CD69 | CD69 molecule | -0.00642968 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.00640012 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00639138 |
| PHF20 | PHD finger protein 20 | -0.00638129 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | -0.0063529 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | -0.00634923 |
| DNASE1L3 | deoxyribonuclease I-like 3 | -0.0063405 |
| CHEK2 | checkpoint kinase 2 | -0.00633741 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | -0.00632861 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | -0.00631601 |
| SPIN1 | spindlin 1 | -0.00629817 |
| MT1G | metallothionein 1G | -0.00629585 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00629497 |
| PAX6 | paired box 6 | -0.00627982 |
| JAG1 | jagged 1 | -0.00626271 |
| KYNU | kynureninase | -0.00625075 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00624657 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.00622688 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.00622474 |
| TUBB4A | tubulin, beta 4A class IVa | -0.00620888 |
| PRDX2 | peroxiredoxin 2 | -0.00620426 |
| TPD52 | tumor protein D52 | -0.00619433 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.0061879 |
| GPR183 | G protein-coupled receptor 183 | -0.00618039 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.00617445 |
| NES | nestin | -0.00617237 |
| SMS | spermine synthase | -0.00617084 |
| ETNPPL | ethanolamine-phosphate phospho-lyase | -0.00616074 |
| FAM172A | family with sequence similarity 172, member A | -0.00616032 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | -0.00615576 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00611297 |
| CTSW | cathepsin W | -0.00610393 |
| CIRBP | cold inducible RNA binding protein | -0.00610016 |
| SUSD6 | sushi domain containing 6 | -0.00609496 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00608352 |
| APOD | apolipoprotein D | -0.00605075 |
| MAOB | monoamine oxidase B | -0.00605046 |
| TMEM14A | transmembrane protein 14A | -0.00602708 |
| HELLS | helicase, lymphoid-specific | -0.00602694 |
| MOAP1 | modulator of apoptosis 1 | -0.00601698 |
| BRD8 | bromodomain containing 8 | -0.00599958 |
| MT1HL1 | metallothionein 1H-like 1 | -0.0059745 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00596157 |
| GPR137B | G protein-coupled receptor 137B | -0.00594113 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00593283 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00592777 |
| PBLD | phenazine biosynthesis-like protein domain containing | -0.00590641 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.00589715 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.00589247 |
| HSD17B4 | hydroxysteroid (17-beta) dehydrogenase 4 | -0.00587791 |
| CDC42 | cell division cycle 42 | -0.00587574 |
| GLUD1 | glutamate dehydrogenase 1 | -0.00587245 |
| SELENOW | selenoprotein W | -0.00587166 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00586087 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.0058589 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | -0.0058539 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.005826 |
| GFAP | glial fibrillary acidic protein | -0.00582276 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.00582151 |
| NFIB | nuclear factor I/B | -0.00581834 |
| FAM53C | family with sequence similarity 53, member C | -0.00580197 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00580184 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00579912 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0057716 |
| FGL1 | fibrinogen-like 1 | -0.00575791 |
| FTO | fat mass and obesity associated | -0.00573359 |
| CERT1 | ceramide transporter 1 | -0.0057329 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00573229 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00571116 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.00569754 |
| ABHD17A | abhydrolase domain containing 17A | -0.00568343 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -0.00567266 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.00566384 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | -0.00565991 |
| AK4 | adenylate kinase 4 | -0.00565738 |
| CLK4 | CDC-like kinase 4 | -0.0056543 |
| RAB14 | RAB14, member RAS oncogene family | -0.00563519 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.00562813 |
| CHN2 | chimerin 2 | -0.0056212 |
| TUBB6 | tubulin, beta 6 class V | -0.00561211 |
| KRT17 | keratin 17, type I | -0.00559911 |
| SF3A3 | splicing factor 3a, subunit 3, 60kDa | -0.00559246 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0055864 |
| S100B | S100 calcium binding protein B | -0.00558029 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00557607 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00557274 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | -0.00556643 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00555865 |
| CRTAM | cytotoxic and regulatory T cell molecule | -0.00555847 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0055561 |
| DOCK4 | dedicator of cytokinesis 4 | -0.00555247 |
| RAP2A | RAP2A, member of RAS oncogene family | -0.00553341 |
| PDGFD | platelet derived growth factor D | -0.00552914 |
| CD9 | CD9 molecule | -0.00552643 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | -0.00552366 |
| RGS1 | regulator of G-protein signaling 1 | -0.00552215 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00551922 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00550516 |
| TBX2 | T-box 2 | -0.00550332 |
| PHGDH | phosphoglycerate dehydrogenase | -0.00548257 |
| CD83 | CD83 molecule | -0.00547169 |
| DMXL1 | Dmx-like 1 | -0.00546723 |
| LSP1 | lymphocyte-specific protein 1 | -0.00546453 |
| FOXG1 | forkhead box G1 | -0.0054599 |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | -0.00545475 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00544909 |
| EDNRB | endothelin receptor type B | -0.00544781 |
| FANCA | Fanconi anemia, complementation group A | -0.00543432 |
| TRAF1 | TNF receptor-associated factor 1 | -0.00542892 |
| TFAM | transcription factor A, mitochondrial | -0.00541156 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00541016 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -0.00540852 |
