SLC1A2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description solute carrier family 1 (glial high affinity glutamate transporter), member 2|This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010] (NCBI Entrez Gene Database, 6506)
External Link http://www.ncbi.nlm.nih.gov/gene/6506
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Genes

70 interacting proteins for SLC1A2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTN2 actinin, alpha 2
AJUBA ajuba LIM protein
AKAP9 A kinase (PRKA) anchor protein 9
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
BCL3 B-cell CLL/lymphoma 3
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CHUK conserved helix-loop-helix ubiquitous kinase
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DLG4 discs, large homolog 4 (Drosophila)
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
E2F4 E2F transcription factor 4, p107/p130-binding
ELK1 ELK1, member of ETS oncogene family
EP300 E1A binding protein p300
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC3 excision repair cross-complementation group 3
ESR1 estrogen receptor 1
ESX1 ESX homeobox 1
GRB2 growth factor receptor-bound protein 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GTF2B general transcription factor IIB
HDAC3 histone deacetylase 3
HIST3H3 histone cluster 3, H3
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
JUN jun proto-oncogene
KAT5 K(lysine) acetyltransferase 5
KLF2 Kruppel-like factor 2
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPT microtubule-associated protein tau
MBD1 methyl-CpG binding domain protein 1
MBD2 methyl-CpG binding domain protein 2
MBD3 methyl-CpG binding domain protein 3
MECP2 methyl CpG binding protein 2
MED1 mediator complex subunit 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NCOA3 nuclear receptor coactivator 3
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NEFL neurofilament, light polypeptide
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
ORC2 origin recognition complex, subunit 2
PIAS2 protein inhibitor of activated STAT, 2
PML promyelocytic leukemia
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
RB1 retinoblastoma 1
RBL2 retinoblastoma-like 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SP1 Sp1 transcription factor
SRF serum response factor (c-fos serum response element-binding transcription factor)
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
UBE2D1 ubiquitin-conjugating enzyme E2D 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZBTB17 zinc finger and BTB domain containing 17
ZBTB33 zinc finger and BTB domain containing 33