SLC22A18 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description solute carrier family 22, member 18|This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Two alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Oct 2010] (NCBI Entrez Gene Database, 5002)
External Link https://ncbi.nlm.nih.gov/gene/5002
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Genes

498 genes differentially expressed following the SLC22A18 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ATF3 activating transcription factor 3 0.0169611
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.0124437
TM4SF1 transmembrane 4 L six family member 1 0.0120928
CD200 CD200 molecule 0.0115814
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.0112289
CCL20 chemokine (C-C motif) ligand 20 0.0107863
GCH1 GTP cyclohydrolase 1 0.0106069
TRIM22 tripartite motif containing 22 0.0105094
MAGEA3 melanoma antigen family A3 0.0103481
LXN latexin 0.00959396
SST somatostatin 0.00959197
MBD1 methyl-CpG binding domain protein 1 0.00957276
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00955717
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00937748
CPE carboxypeptidase E 0.00932938
CEMIP cell migration inducing protein, hyaluronan binding 0.00928574
ISG20 interferon stimulated exonuclease gene 20kDa 0.00915603
RALB v-ral simian leukemia viral oncogene homolog B 0.00902766
CXCL8 chemokine (C-X-C motif) ligand 8 0.00886326
FGF13 fibroblast growth factor 13 0.00885754
AK4 adenylate kinase 4 0.00880274
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00879435
MAL mal, T-cell differentiation protein 0.00877757
GM2A GM2 ganglioside activator 0.0086762
PTK2 protein tyrosine kinase 2 0.00851998
S100A9 S100 calcium binding protein A9 0.00851003
S100A10 S100 calcium binding protein A10 0.00844361
SELL selectin L 0.00839356
APOA1 apolipoprotein A-I 0.00836274
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.00825753
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00811807
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00801769
CCNG1 cyclin G1 0.00800093
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.00784812
CNOT4 CCR4-NOT transcription complex, subunit 4 0.0078345
ANXA3 annexin A3 0.00780672
PEG3 paternally expressed 3 0.00773411
TPM4 tropomyosin 4 0.00772612
MT1F metallothionein 1F 0.00765167
CHMP2B charged multivesicular body protein 2B 0.00759492
GOLT1B golgi transport 1B 0.00757497
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00753675
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00749369
ERAP2 endoplasmic reticulum aminopeptidase 2 0.0074503
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00744719
MRPL18 mitochondrial ribosomal protein L18 0.00743796
FN1 fibronectin 1 0.00740192
ATP5F1C ATP synthase F1 subunit gamma 0.00738474
EDN3 endothelin 3 0.00735643
APOB apolipoprotein B 0.0073508
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00732633
MT1M metallothionein 1M 0.00730315
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 0.00728493
MAP2K5 mitogen-activated protein kinase kinase 5 0.0072731
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00726252
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00725474
GNAS GNAS complex locus 0.00723288
SKAP2 src kinase associated phosphoprotein 2 0.00721469
CTSS cathepsin S 0.00721415
ARMCX1 armadillo repeat containing, X-linked 1 0.00715766
MPO myeloperoxidase 0.00715592
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.00714902
PFKP phosphofructokinase, platelet 0.0071466
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.00713743
YPEL5 yippee-like 5 (Drosophila) 0.00712193
ADAMDEC1 ADAM-like, decysin 1 0.00711888
CSTA cystatin A (stefin A) 0.00711106
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00708756
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00708524
TFRC transferrin receptor 0.00706165
EMX2 empty spiracles homeobox 2 0.00704395
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00694762
IPW imprinted in Prader-Willi syndrome (non-protein coding) 0.00679963
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 0.00679069
BEX4 brain expressed, X-linked 4 0.00678746
C3ORF14 chromosome 3 open reading frame 14 0.00678563
TP53I3 tumor protein p53 inducible protein 3 0.00677649
DMAC2L distal membrane arm assembly component 2 like 0.00674041
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.00670696
FABP7 fatty acid binding protein 7, brain 0.00667622
PLSCR1 phospholipid scramblase 1 0.00667575
CNIH1 cornichon family AMPA receptor auxiliary protein 1 0.00666234
STX7 syntaxin 7 0.00665427
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00664719
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.00664515
H1-2 H1.2 linker histone, cluster member 0.00662192
TNIP1 TNFAIP3 interacting protein 1 0.00659247
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.00658254
CREM cAMP responsive element modulator 0.00657526
ADD3 adducin 3 (gamma) 0.00653192
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 0.00652783
PLP1 proteolipid protein 1 0.00651944
ITM2A integral membrane protein 2A 0.00650997
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) 0.00650173
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.00647179
ANXA1 annexin A1 0.00646896
LGALS13 lectin, galactoside-binding, soluble, 13 0.00646211
DARS1 aspartyl-tRNA synthetase 1 0.00645407
DEFA5 defensin, alpha 5, Paneth cell-specific 0.00644285
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.00642184
TRH thyrotropin-releasing hormone 0.0064198
RPS27L ribosomal protein S27-like 0.00641612
MT2A metallothionein 2A 0.00640904
MMP9 matrix metallopeptidase 9 0.00640575
CD69 CD69 molecule 0.00640567
BTF3P11 basic transcription factor 3 pseudogene 11 0.00639382
BDH2 3-hydroxybutyrate dehydrogenase, type 2 0.00638508
LPAR6 lysophosphatidic acid receptor 6 0.0063835
SLC35G2 solute carrier family 35, member G2 0.00637429
IFT20 intraflagellar transport 20 0.0063481
BCL2A1 BCL2-related protein A1 0.00634432
DOK5 docking protein 5 0.00633845
ADSL adenylosuccinate lyase 0.00633749
RBKS ribokinase 0.00632924
THBS1 thrombospondin 1 0.00631409
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.00629833
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.00629575
PRAME preferentially expressed antigen in melanoma 0.00629151
CCK cholecystokinin 0.00627025
IFT52 intraflagellar transport 52 0.00623874
MICA MHC class I polypeptide-related sequence A 0.0062348
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 0.00622698
RPP40 ribonuclease P/MRP 40kDa subunit 0.00620173
REG1A regenerating islet-derived 1 alpha 0.00620009
MRPS33 mitochondrial ribosomal protein S33 0.00619489
SOD2 superoxide dismutase 2, mitochondrial 0.00612213
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.00609865
PXDN peroxidasin 0.00606538
KYNU kynureninase 0.0060547
C6ORF48 chromosome 6 open reading frame 48 0.00602225
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.0060082
STXBP6 syntaxin binding protein 6 (amisyn) 0.0060057
GMFB glia maturation factor, beta 0.00600117
GBP2 guanylate binding protein 2, interferon-inducible 0.00597636
VAMP5 vesicle-associated membrane protein 5 0.00597462
BTG3 BTG family, member 3 0.00596851
CD83 CD83 molecule 0.00594911
CD59 CD59 molecule, complement regulatory protein 0.00594766
SRPX2 sushi-repeat containing protein, X-linked 2 0.00594706
IFNGR1 interferon gamma receptor 1 0.00592865
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.00592656
BEX1 brain expressed, X-linked 1 0.00589592
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 0.00589308
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.00589073
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.00588676
GDI2 GDP dissociation inhibitor 2 0.00587807
SNAP23 synaptosomal-associated protein, 23kDa 0.00586701
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00586419
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00585118
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00583989
CAST calpastatin 0.00583616
SPINK4 serine peptidase inhibitor, Kazal type 4 0.00580883
MYO1C myosin IC 0.0058036
ERGIC3 ERGIC and golgi 3 0.00580085
MEOX2 mesenchyme homeobox 2 0.00578821
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00578235
SRPRB signal recognition particle receptor, B subunit 0.00577332
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.0057716
DDIT3 DNA-damage-inducible transcript 3 0.0057518
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.00574603
RIPK2 receptor-interacting serine-threonine kinase 2 0.00574256
RIPOR2 RHO family interacting cell polarization regulator 2 0.00574195
REEP5 receptor accessory protein 5 0.00573346
RNASET2 ribonuclease T2 0.00573133
ATOX1 antioxidant 1 copper chaperone 0.00568341
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.00568324
GSTO1 glutathione S-transferase omega 1 0.00567816
TOGARAM1 TOG array regulator of axonemal microtubules 1 0.00567382
KLF4 Kruppel-like factor 4 (gut) 0.00566957
SEC23A Sec23 homolog A (S. cerevisiae) 0.00566665
CD48 CD48 molecule 0.00563179
MT1G metallothionein 1G 0.005612
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 0.00561175
CYB5R4 cytochrome b5 reductase 4 0.00558818
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.00558694
SSPN sarcospan 0.00557692
EVI2A ecotropic viral integration site 2A 0.00557578
MRPL39 mitochondrial ribosomal protein L39 0.00556525
CXCL11 chemokine (C-X-C motif) ligand 11 0.00555201
FBXL12 F-box and leucine-rich repeat protein 12 0.00554933
PTPRG protein tyrosine phosphatase, receptor type, G 0.0055489
LHFPL2 lipoma HMGIC fusion partner-like 2 0.00553764
BIRC3 baculoviral IAP repeat containing 3 0.00553349
CLINT1 clathrin interactor 1 0.00549905
TPK1 thiamin pyrophosphokinase 1 0.00549844
FKBP14 FK506 binding protein 14, 22 kDa 0.00549568
ANO10 anoctamin 10 0.00548399
RARS1 arginyl-tRNA synthetase 1 0.00547796
TMEM126B transmembrane protein 126B 0.00546217
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00546019
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 0.0054479
LYZ lysozyme 0.00544333
NCOA4 nuclear receptor coactivator 4 0.0054381
ITM2C integral membrane protein 2C 0.00543743
PNO1 partner of NOB1 homolog (S. cerevisiae) 0.00541842
SNX3 sorting nexin 3 0.00541467
ZG16 zymogen granule protein 16 0.00541355
ARF3 ADP-ribosylation factor 3 0.00540754
MDH1 malate dehydrogenase 1, NAD (soluble) 0.00540095
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.00538125
C1ORF54 chromosome 1 open reading frame 54 0.00538099
TCEAL2 transcription elongation factor A (SII)-like 2 0.00537619
TCL1A T-cell leukemia/lymphoma 1A 0.00536335
TSLIG2 tRNA splicing ligase complex subunit 2 0.0053599
TGIF1 TGFB-induced factor homeobox 1 0.00535408
TSPAN6 tetraspanin 6 0.00533568
MRPL40 mitochondrial ribosomal protein L40 0.00533314
SNUPN snurportin 1 0.00531659
MTIF2 mitochondrial translational initiation factor 2 0.00531265
PRKD3 protein kinase D3 0.00530857
STX12 syntaxin 12 0.00530606
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 0.00530488
TMEM230 transmembrane protein 230 0.00530448
RAP1B RAP1B, member of RAS oncogene family 0.00529187
IFI16 interferon, gamma-inducible protein 16 0.00528688
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0052859
WDR61 WD repeat domain 61 0.00526683
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.0052535
RBM7 RNA binding motif protein 7 0.00524858
SLC16A4 solute carrier family 16, member 4 0.00524392
MTUS1 microtubule associated tumor suppressor 1 0.00523033
CLCA1 chloride channel accessory 1 0.00523004
RMDN3 regulator of microtubule dynamics 3 0.00522379
C5ORF30 chromosome 5 open reading frame 30 0.00521608
MAGEA12 melanoma antigen family A12 0.00520595
KRT81 keratin 81, type II 0.00520152
TMEM242 transmembrane protein 242 0.00519711
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00518529
CNN3 calponin 3, acidic 0.00518339
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00517429
SCG5 secretogranin V 0.00517304
PLIN2 perilipin 2 0.00515494
HSPA8 heat shock 70kDa protein 8 0.0051529
NDN necdin, melanoma antigen (MAGE) family member 0.00514214
HEXA hexosaminidase A (alpha polypeptide) 0.00513629
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.0051335
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 0.00511047
WARS1 tryptophanyl-tRNA synthetase 1 0.00508419
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa 0.00508129
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.00507932
LZTS3 leucine zipper, putative tumor suppressor family member 3 0.00507833
COG5 component of oligomeric golgi complex 5 0.00506614
UGP2 UDP-glucose pyrophosphorylase 2 0.00506025
ZBED8 zinc finger, BED-type containing 8 0.00505751
OLFML3 olfactomedin-like 3 0.00505098
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 0.00505063
RND1 Rho family GTPase 1 0.00504908
CXCL10 chemokine (C-X-C motif) ligand 10 0.00504773
CRIPT cysteine-rich PDZ-binding protein 0.00504431

decreased expression

Symbol Name Standardized Value
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0179264
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.0126735
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0124539
TM9SF3 transmembrane 9 superfamily member 3 -0.0124032
PTCH1 patched 1 -0.0121353
SIRT3 sirtuin 3 -0.0115204
PBX3 pre-B-cell leukemia homeobox 3 -0.0109575
BGN biglycan -0.0104918
RXRA retinoid X receptor, alpha -0.0101065
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.010087
SLIT2 slit homolog 2 (Drosophila) -0.0100803
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00994421
MCOLN1 mucolipin 1 -0.00983121
HIP1 huntingtin interacting protein 1 -0.00932809
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.00924951
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00910279
A2M alpha-2-macroglobulin -0.00901675
LY6E lymphocyte antigen 6 complex, locus E -0.00894419
TPD52 tumor protein D52 -0.00887708
AQP3 aquaporin 3 (Gill blood group) -0.00884875
KRT14 keratin 14, type I -0.00873012
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.00867966
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00860359
RAPSN receptor-associated protein of the synapse -0.00856748
GPSM2 G-protein signaling modulator 2 -0.00853855
C1R complement component 1, r subcomponent -0.00846257
MYH11 myosin, heavy chain 11, smooth muscle -0.0083878
HELLS helicase, lymphoid-specific -0.00829246
GLOD4 glyoxalase domain containing 4 -0.00827841
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00815465
LIMCH1 LIM and calponin homology domains 1 -0.00805015
EXPH5 exophilin 5 -0.00804123
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00803655
CIT citron rho-interacting serine/threonine kinase -0.00800476
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00793432
NXN nucleoredoxin -0.00780167
NSD2 nuclear receptor binding SET domain protein 2 -0.00779678
ADCY9 adenylate cyclase 9 -0.00777575
KAZN kazrin, periplakin interacting protein -0.0077748
ZBTB18 zinc finger and BTB domain containing 18 -0.00775654
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00774858
NDNF neuron-derived neurotrophic factor -0.00762161
COL6A2 collagen, type VI, alpha 2 -0.00754634
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00754375
SLC16A6 solute carrier family 16, member 6 -0.00752898
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.00748995
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -0.00748168
SDC1 syndecan 1 -0.00746641
GRB14 growth factor receptor-bound protein 14 -0.00744895
RCAN2 regulator of calcineurin 2 -0.00743097
LTBP2 latent transforming growth factor beta binding protein 2 -0.00736373
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.00733741
SPARCL1 SPARC-like 1 (hevin) -0.00728442
NVL nuclear VCP-like -0.00726593
TTC39A tetratricopeptide repeat domain 39A -0.00726182
SCGB1D2 secretoglobin, family 1D, member 2 -0.00725794
RAB40B RAB40B, member RAS oncogene family -0.007249
KLF5 Kruppel-like factor 5 (intestinal) -0.00722512
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00720674
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha -0.00719903
GATAD2A GATA zinc finger domain containing 2A -0.00719855
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00719493
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00714674
PPL periplakin -0.00712342
LMNB2 lamin B2 -0.00711115
ACTN4 actinin, alpha 4 -0.0071026
DACH1 dachshund family transcription factor 1 -0.00708178
ANGPTL2 angiopoietin-like 2 -0.00705157
TMSB15A thymosin beta 15a -0.00704669
TPSAB1 tryptase alpha/beta 1 -0.0070442
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.0069816
KIF14 kinesin family member 14 -0.00696716
GSE1 Gse1 coiled-coil protein -0.00695924
CTBP2 C-terminal binding protein 2 -0.00694043
CD14 CD14 molecule -0.00692877
ARID1A AT rich interactive domain 1A (SWI-like) -0.00690724
PCDH9 protocadherin 9 -0.00689016
CUEDC1 CUE domain containing 1 -0.00687346
TECR trans-2,3-enoyl-CoA reductase -0.00684739
JAG2 jagged 2 -0.00684445
PEG10 paternally expressed 10 -0.00683988
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.0068013
PRPF4 pre-mRNA processing factor 4 -0.00678027
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00677184
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00675747
SNX11 sorting nexin 11 -0.00674904
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00674699
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -0.00672677
NFIB nuclear factor I/B -0.00671804
TP63 tumor protein p63 -0.00667609
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -0.00665564
TNS3 tensin 3 -0.00664586
SP2 Sp2 transcription factor -0.0066442
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -0.00664301
RRBP1 ribosome binding protein 1 -0.00664218
RAD21 RAD21 homolog (S. pombe) -0.00662044
C1QB complement component 1, q subcomponent, B chain -0.00658448
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.00658419
PWWP3A PWWP domain containing 3A, DNA repair factor -0.00657343
CTSZ cathepsin Z -0.00656465
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.0065553
SCRIB scribbled planar cell polarity protein -0.00652666
BAHCC1 BAH domain and coiled-coil containing 1 -0.00651336
CBX1 chromobox homolog 1 -0.00650818
NAV2 neuron navigator 2 -0.00649404
PRDX2 peroxiredoxin 2 -0.00648553
TAGLN transgelin -0.0064504
RRM1 ribonucleotide reductase M1 -0.00643587
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00643163
CD163 CD163 molecule -0.00641179
RAB14 RAB14, member RAS oncogene family -0.00639355
ESRP2 epithelial splicing regulatory protein 2 -0.00638845
DGS2 DiGeorge syndrome/velocardiofacial syndrome complex 2 -0.00638571
ADGRF5 adhesion G protein-coupled receptor F5 -0.00638083
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -0.00635353
BRD2 bromodomain containing 2 -0.00635016
MGP matrix Gla protein -0.00634406
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -0.00634004
PIP prolactin-induced protein -0.00633675
KANK2 KN motif and ankyrin repeat domains 2 -0.00631923
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00629366
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00629041
SCGB2A2 secretoglobin, family 2A, member 2 -0.00628537
BAD BCL2-associated agonist of cell death -0.00628175
HOXC6 homeobox C6 -0.00628066
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.0062793
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -0.00626817
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.00626453
NBPF10 neuroblastoma breakpoint family, member 10 -0.0062522
KLF13 Kruppel-like factor 13 -0.00623386
PUF60 poly-U binding splicing factor 60KDa -0.00620349
KIAA0232 KIAA0232 -0.00620015
TMPRSS4 transmembrane protease, serine 4 -0.00618983
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00615917
TXLNA taxilin alpha -0.00615119
IRAK1 interleukin-1 receptor-associated kinase 1 -0.00614221
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor -0.00611629
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -0.00610864
HOPX HOP homeobox -0.00610012
TRPS1 trichorhinophalangeal syndrome I -0.00609686
PLAAT3 phospholipase A and acyltransferase 3 -0.00608682
MTCL1 microtubule crosslinking factor 1 -0.00607761
TNK2 tyrosine kinase, non-receptor, 2 -0.00606646
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00606365
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.00603195
PFKL phosphofructokinase, liver -0.00602607
FBLN1 fibulin 1 -0.00602168
SPIN1 spindlin 1 -0.00601322
KLK11 kallikrein-related peptidase 11 -0.00599974
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00597815
CPT1A carnitine palmitoyltransferase 1A (liver) -0.00596312
GTSE1 G-2 and S-phase expressed 1 -0.005944
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00593099
CENPF centromere protein F, 350/400kDa -0.00591878
FUS FUS RNA binding protein -0.00591762
CSF1R colony stimulating factor 1 receptor -0.00590694
ENAH enabled homolog (Drosophila) -0.00590428
PRPF3 pre-mRNA processing factor 3 -0.00588238
COL3A1 collagen, type III, alpha 1 -0.00587243
PRPF8 pre-mRNA processing factor 8 -0.00586063
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.0058568
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -0.00585467
MYLK myosin light chain kinase -0.00583915
EML3 echinoderm microtubule associated protein like 3 -0.00583526
KRT16 keratin 16, type I -0.00582252
UBE2S ubiquitin-conjugating enzyme E2S -0.00582115
NCOA2 nuclear receptor coactivator 2 -0.00582102
IL7R interleukin 7 receptor -0.00581986
FEN1 flap structure-specific endonuclease 1 -0.00580788
FBP1 fructose-1,6-bisphosphatase 1 -0.00579912
MCM7 minichromosome maintenance complex component 7 -0.00579151
NCOR2 nuclear receptor corepressor 2 -0.00578521
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00578518
NOTCH1 notch 1 -0.00577827
CCR1 chemokine (C-C motif) receptor 1 -0.00577777
MICU2 mitochondrial calcium uptake 2 -0.00577131
TNS1 tensin 1 -0.00576074
JCHAIN joining chain of multimeric IgA and IgM -0.00573132
PNPLA6 patatin-like phospholipase domain containing 6 -0.0057072
DLG5 discs, large homolog 5 (Drosophila) -0.00570579
MED13 mediator complex subunit 13 -0.00569109
LMNB1 lamin B1 -0.00568917
ECPAS Ecm29 proteasome adaptor and scaffold -0.00568383
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00568169
FAM120A family with sequence similarity 120A -0.00567377
AEBP1 AE binding protein 1 -0.00567281
HMGB1 high mobility group box 1 -0.00566692
SNX7 sorting nexin 7 -0.00564858
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00563775
TMEM45A transmembrane protein 45A -0.00562987
DGCR8 DGCR8 microprocessor complex subunit -0.00562874
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.00561792
SRRT serrate, RNA effector molecule -0.00561022
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -0.00560148
SRRM2 serine/arginine repetitive matrix 2 -0.00559946
CLIC3 chloride intracellular channel 3 -0.00559255
ANXA6 annexin A6 -0.00558277
COL6A1 collagen, type VI, alpha 1 -0.00558033
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00557826
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -0.00557468
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00556692
INSR insulin receptor -0.0055651
TIMELESS timeless circadian clock -0.00555089
DUSP7 dual specificity phosphatase 7 -0.00554214
ACADVL acyl-CoA dehydrogenase, very long chain -0.00553993
FBLN2 fibulin 2 -0.00553777
MACROD1 MACRO domain containing 1 -0.00553279
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.00551521
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00550691
PUM1 pumilio RNA-binding family member 1 -0.00550594
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -0.00549629
FAM110B family with sequence similarity 110, member B -0.00548313
STEAP3 STEAP family member 3, metalloreductase -0.00548093
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00547551
SPRR1B small proline-rich protein 1B -0.00547435
KRT1 keratin 1, type II -0.00546681
DVL1 dishevelled segment polarity protein 1 -0.00546036
USP47 ubiquitin specific peptidase 47 -0.00545897
CDC25B cell division cycle 25B -0.00545296
CEP55 centrosomal protein 55kDa -0.0054509
APOD apolipoprotein D -0.00543769
ATAD2 ATPase family, AAA domain containing 2 -0.00543526
COQ8A coenzyme Q8A -0.00543402
GPC1 glypican 1 -0.0054332
ARAF A-Raf proto-oncogene, serine/threonine kinase -0.00542892
ANKRD10 ankyrin repeat domain 10 -0.00542055
RALGDS ral guanine nucleotide dissociation stimulator -0.00541693
CCL13 chemokine (C-C motif) ligand 13 -0.0053973
ATMIN ATM interactor -0.00539549
SEPTIN10 septin 10 -0.00538878
JUND jun D proto-oncogene -0.0053884
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) -0.0053869
AUTS2 autism susceptibility candidate 2 -0.00538628
PTK7 protein tyrosine kinase 7 (inactive) -0.00538595
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -0.00538133
METRN meteorin, glial cell differentiation regulator -0.00537395
PKN1 protein kinase N1 -0.00537225
F13A1 coagulation factor XIII, A1 polypeptide -0.00537038
SFTPB surfactant protein B -0.0053694
RAB8A RAB8A, member RAS oncogene family -0.00536355
IGFBP4 insulin-like growth factor binding protein 4 -0.00535795
PHF1 PHD finger protein 1 -0.00535119
CFD complement factor D (adipsin) -0.00533025
GPX4 glutathione peroxidase 4 -0.00532897
ENG endoglin -0.00532497
KIF20A kinesin family member 20A -0.00532253
PRKCZ protein kinase C, zeta -0.0053154
SPON2 spondin 2, extracellular matrix protein -0.00531404
CD320 CD320 molecule -0.00531272