SLX4 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SLX4 structure-specific endonuclease subunit|This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.[provided by RefSeq, Jan 2011] (NCBI Entrez Gene Database, 84464)
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Genes

473 genes differentially expressed following the SLX4 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
INSYN2B inhibitory synaptic factor family member 2B 3.09377
CTXN2 cortexin 2 3.09377
IGFLR1 IGF-like family receptor 1 3.09377
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 3.09377
LSMEM2 leucine-rich single-pass membrane protein 2 3.09377
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 3.09377
ASPG asparaginase 3.09377
GSG1L GSG1-like 3.09377
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like 3.09377
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 3.09377
PTAFR platelet-activating factor receptor 3.09377
AK8 adenylate kinase 8 3.09377
TSSK6 testis-specific serine kinase 6 3.09377
BAALC brain and acute leukemia, cytoplasmic 3.09377
INHA inhibin, alpha 3.09377
OVGP1 oviductal glycoprotein 1, 120kDa 3.09377
KCTD19 potassium channel tetramerization domain containing 19 3.09377
FLNC filamin C, gamma 3.09377
HRK harakiri, BCL2 interacting protein 3.09377
CD200R1L CD200 receptor 1-like 3.09377
DDIT3 DNA-damage-inducible transcript 3 3.09377
HHAT hedgehog acyltransferase 3.09377
NUTM2G NUT family member 2G 3.09377
ATAD3C ATPase family, AAA domain containing 3C 3.09377
RAI1 retinoic acid induced 1 3.09377
EDAR ectodysplasin A receptor 3.09377
FLT3LG fms-related tyrosine kinase 3 ligand 3.09377
IL17C interleukin 17C 3.09377
OTOF otoferlin 3.09377
MAGEL2 melanoma antigen family L2 3.09377
GDF15 growth differentiation factor 15 3.09377
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 3.09377
LMO1 LIM domain only 1 (rhombotin 1) 2.96502
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.96502
PLIN1 perilipin 1 2.96502
C8ORF48 chromosome 8 open reading frame 48 2.96502
TBX15 T-box 15 2.96502
PGAM4 phosphoglycerate mutase family member 4 2.96502
LRRTM2 leucine rich repeat transmembrane neuronal 2 2.96502
TRIM17 tripartite motif containing 17 2.96502
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 2.96502
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 2.96502
IPCEF1 interaction protein for cytohesin exchange factors 1 2.96502
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 2.96502
TRPC3 transient receptor potential cation channel, subfamily C, member 3 2.96502
ERN2 endoplasmic reticulum to nucleus signaling 2 2.96502
NANOS1 nanos homolog 1 (Drosophila) 2.96502
MTTP microsomal triglyceride transfer protein 2.96502
PLK3 polo-like kinase 3 2.96502
TMEM200C transmembrane protein 200C 2.96502
FBXL17 F-box and leucine-rich repeat protein 17 2.96502
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 2.96502
SPON2 spondin 2, extracellular matrix protein 2.96502
DCLRE1B DNA cross-link repair 1B 2.96502
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 2.96502
ACRBP acrosin binding protein 2.96502
CCDC83 coiled-coil domain containing 83 2.96502
RNASE9 ribonuclease, RNase A family, 9 (non-active) 2.96502
MAP3K9 mitogen-activated protein kinase kinase kinase 9 2.96502
MAGED4 melanoma antigen family D4 2.96502
GPR183 G protein-coupled receptor 183 2.96502
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.96502
RCSD1 RCSD domain containing 1 2.96502
DDR2 discoidin domain receptor tyrosine kinase 2 2.96502
COL16A1 collagen, type XVI, alpha 1 2.96502
OPRL1 opiate receptor-like 1 2.96502
TAL2 T-cell acute lymphocytic leukemia 2 2.96502
C11ORF86 chromosome 11 open reading frame 86 2.96502
TCAF2 TRPM8 channel-associated factor 2 2.96502
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10 2.96502
TRPV2 transient receptor potential cation channel, subfamily V, member 2 2.96502
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 2.96502
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 2.96502
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.96502
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 2.96502
BKGD beta-keto-L-gulonate decarboxylase 2.96502
MGAM maltase-glucoamylase 2.96502
ZNF221 zinc finger protein 221 2.96502
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 2.96502
MUSTN1 musculoskeletal, embryonic nuclear protein 1 2.96502
TRIM34 tripartite motif containing 34 2.96502
ACSL6 acyl-CoA synthetase long-chain family member 6 2.96502
MYPN myopalladin 2.96502
GCSAM germinal center-associated, signaling and motility 2.96502
SMTNL2 smoothelin-like 2 2.96502
SMTNL1 smoothelin-like 1 2.96502
MAGIX MAGI family member, X-linked 2.96502
KL klotho 2.96502
VN1R1 vomeronasal 1 receptor 1 2.96502
FKBP6 FK506 binding protein 6, 36kDa 2.96502
ACKR5 atypical chemokine receptor 5 2.96502
LINC02560 long intergenic non-protein coding RNA 2560 2.96502
PRRT1B proline rich transmembrane protein 1B 2.96502
CIMAP1D CIMAP1 family member D 2.96502
OOSP4B oocyte secreted protein family member 4B 2.96502
C1ORF202 chromosome 1 open reading frame 202 2.96502
H4C11 H4 clustered histone 11 2.96502
ZNG1F Zn regulated GTPase metalloprotein activator 1F 2.96502
DEPP1 DEPP autophagy regulator 1 2.96502
SEPTIN4 septin 4 2.96502
FAM13C family with sequence similarity 13, member C 2.96502
LAT linker for activation of T cells 2.96502
TIMD4 T-cell immunoglobulin and mucin domain containing 4 2.96502
HID1 HID1 domain containing 2.96502
ZNF583 zinc finger protein 583 2.96502
GJA3 gap junction protein, alpha 3, 46kDa 2.96502
TMPRSS11F transmembrane protease, serine 11F 2.96502
SLFN11 schlafen family member 11 2.96502
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 2.96502
TXLNB taxilin beta 2.96502
NECAB2 N-terminal EF-hand calcium binding protein 2 2.96502
DNAJC5G DnaJ (Hsp40) homolog, subfamily C, member 5 gamma 2.96502
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 2.96502
FGD3 FYVE, RhoGEF and PH domain containing 3 2.96502
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 2.96502
PROKR1 prokineticin receptor 1 2.96502
AKAP3 A kinase (PRKA) anchor protein 3 2.96502
SYCP2 synaptonemal complex protein 2 2.96502
UTS2 urotensin 2 2.96502
CCDC121 coiled-coil domain containing 121 2.96502
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4 2.96502
CBLN1 cerebellin 1 precursor 2.96502
THPO thrombopoietin 2.96502
TSGA10IP testis specific, 10 interacting protein 2.96502
CCDC13 coiled-coil domain containing 13 2.96502
PCDHB12 protocadherin beta 12 2.96502
IL15RA interleukin 15 receptor, alpha 2.96502
LOC390937 Ets2 repressor factor-like 2.96502
ISM2 isthmin 2 2.96502
CES3 carboxylesterase 3 2.96502
ZNF492 zinc finger protein 492 2.96502
STAB1 stabilin 1 2.96502
CDHR5 cadherin-related family member 5 2.96502
TIGD3 tigger transposable element derived 3 2.96502
TMEM61 transmembrane protein 61 2.96502
GOLGA6D golgin A6 family, member D 2.96502
CALHM1 calcium homeostasis modulator 1 2.96502
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 2.96502
NIPAL4 NIPA-like domain containing 4 2.96502
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.96502
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 2.96502
HUS1B HUS1 checkpoint homolog b (S. pombe) 2.96502
DRD4 dopamine receptor D4 2.96502
HCK HCK proto-oncogene, Src family tyrosine kinase 2.96502
DCLK3 doublecortin-like kinase 3 2.96502
NOX1 NADPH oxidase 1 2.96502
ALAS2 5'-aminolevulinate synthase 2 2.96502
RPA4 replication protein A4, 30kDa 2.96502
NACAD NAC alpha domain containing 2.96502
CCDC154 coiled-coil domain containing 154 2.96502
FNDC5 fibronectin type III domain containing 5 2.96502
LRRC43 leucine rich repeat containing 43 2.96502
CH25H cholesterol 25-hydroxylase 2.96502
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 2.96502
CERKL ceramide kinase-like 2.96502
EBLN1 endogenous Bornavirus-like nucleoprotein 1 2.96502
PIH1D2 PIH1 domain containing 2 2.96502
SHISA8 shisa family member 8 2.96502
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 2.96502
VWA7 von Willebrand factor A domain containing 7 2.96502
LSMEM1 leucine-rich single-pass membrane protein 1 2.96502
CDH17 cadherin 17, LI cadherin (liver-intestine) 2.96502
CDH22 cadherin 22, type 2 2.96502
INSL3 insulin-like 3 (Leydig cell) 2.96502
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type 2.96502
EXD1 exonuclease 3'-5' domain containing 1 2.96502
ADAM18 ADAM metallopeptidase domain 18 2.96502
CNR1 cannabinoid receptor 1 (brain) 2.96502
BTG4 B-cell translocation gene 4 2.96502
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 2.96502
CCDC178 coiled-coil domain containing 178 2.96502
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 2.96502
TG thyroglobulin 2.96502
USP35 ubiquitin specific peptidase 35 2.96502
ISL1 ISL LIM homeobox 1 2.96502
TEX19 testis expressed 19 2.96502
ZCCHC18 zinc finger, CCHC domain containing 18 2.96502
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 2.96502
NTF4 neurotrophin 4 2.96502
SST somatostatin 2.96502
KLK7 kallikrein-related peptidase 7 2.96502
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 2.96502
SVOP SV2 related protein homolog (rat) 2.96502
BEAN1 brain expressed, associated with NEDD4, 1 2.96502
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2 2.96502
NEIL1 nei endonuclease VIII-like 1 (E. coli) 2.96502
SLC36A3 solute carrier family 36, member 3 2.96502
PYHIN1 pyrin and HIN domain family, member 1 2.96502
CD36 CD36 molecule (thrombospondin receptor) 2.96502
AZGP1 alpha-2-glycoprotein 1, zinc-binding 2.96502
ADM5 adrenomedullin 5 (putative) 2.96502
STMND1 stathmin domain containing 1 2.96502
AOC1 amine oxidase, copper containing 1 2.96502
MAEL maelstrom spermatogenic transposon silencer 2.96502
SGK2 serum/glucocorticoid regulated kinase 2 2.96502
NUTM2A NUT family member 2A 2.96502
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 2.96502
AMER3 APC membrane recruitment protein 3 2.96502
TESK1 testis-specific kinase 1 2.96502
POPDC2 popeye domain containing 2 2.96502
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9 2.96502
ROM1 retinal outer segment membrane protein 1 2.96502
TBC1D26 TBC1 domain family, member 26 2.96502
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 2.96502
IL17B interleukin 17B 2.96502
ZHX1 zinc fingers and homeoboxes 1 2.96502
NKX6-2 NK6 homeobox 2 2.96502
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.96502
SLX1B SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) 2.96502
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 2.96502
ADAM20 ADAM metallopeptidase domain 20 2.96502
POTEJ POTE ankyrin domain family, member J 2.96502
TMEM45B transmembrane protein 45B 2.96502
CSPG4 chondroitin sulfate proteoglycan 4 2.96502
CFAP221 cilia and flagella associated protein 221 2.96502
ADRA1B adrenoceptor alpha 1B 2.96502
GRM2 glutamate receptor, metabotropic 2 2.96502
NAP1L5 nucleosome assembly protein 1-like 5 2.96502
ARMCX6 armadillo repeat containing, X-linked 6 2.96502
ASIC2 acid sensing (proton gated) ion channel 2 2.7618
CUL9 cullin 9 2.75502
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 2.74728
PCOLCE2 procollagen C-endopeptidase enhancer 2 2.73456
PLXNA3 plexin A3 2.68417
EFCAB5 EF-hand calcium binding domain 5 2.68417
MAPRE3 microtubule-associated protein, RP/EB family, member 3 2.67987
ADAM28 ADAM metallopeptidase domain 28 2.67987
FES FES proto-oncogene, tyrosine kinase 2.67987
EXPH5 exophilin 5 2.67982
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 2.65341
DGKI diacylglycerol kinase, iota 2.65341
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 2.58029
DUSP18 dual specificity phosphatase 18 2.57979
CARHSP1 calcium regulated heat stable protein 1, 24kDa 2.52675
RRAS2 related RAS viral (r-ras) oncogene homolog 2 2.49222
BMP2 bone morphogenetic protein 2 2.45576
RAB6B RAB6B, member RAS oncogene family 2.44644
FAM53A family with sequence similarity 53, member A 2.4393
TMEM74B transmembrane protein 74B 2.4393
DNAI3 dynein axonemal intermediate chain 3 2.4393
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) 2.4393
MICU3 mitochondrial calcium uptake family, member 3 2.4393
AKAP17A A kinase (PRKA) anchor protein 17A 2.42219
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 2.39831
FAM111B family with sequence similarity 111, member B 2.39831
MINDY2 MINDY lysine 48 deubiquitinase 2 2.39271
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 2.37068
KAZN kazrin, periplakin interacting protein 2.34266
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 2.34045
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 2.32516
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.31398
TGFA transforming growth factor, alpha 2.30203
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 2.2968
RAI14 retinoic acid induced 14 2.29149
THAP2 THAP domain containing, apoptosis associated protein 2 2.283
THNSL2 threonine synthase-like 2 (S. cerevisiae) 2.27448
MRPS9 mitochondrial ribosomal protein S9 2.2476
FAM111A family with sequence similarity 111, member A 2.23007
TMEM38B transmembrane protein 38B 2.22289
ZNF830 zinc finger protein 830 2.20527
SMG7 SMG7 nonsense mediated mRNA decay factor 2.19448
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 2.18533
CEP70 centrosomal protein 70kDa 2.18512
C3ORF38 chromosome 3 open reading frame 38 2.17206
AAK1 AP2 associated kinase 1 2.17206
ELF1 E74-like factor 1 (ets domain transcription factor) 2.15659
ACADSB acyl-CoA dehydrogenase, short/branched chain 2.14926
NEK2 NIMA-related kinase 2 2.14847
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 2.13849
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 2.12689
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 2.11863
MFAP2 microfibrillar-associated protein 2 2.09375
ADARB1 adenosine deaminase, RNA-specific, B1 2.08849
SNX14 sorting nexin 14 2.08849
CNOT1 CCR4-NOT transcription complex, subunit 1 2.07853
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) 2.07368
RASEF RAS and EF-hand domain containing 2.04938
USP31 ubiquitin specific peptidase 31 2.04173
CNBD1 cyclic nucleotide binding domain containing 1 2.03047
WNK1 WNK lysine deficient protein kinase 1 2.02326
ELOA elongin A 2.01023
TSPAN13 tetraspanin 13 2.01023
RHOQ ras homolog family member Q 2.01023
TMEM64 transmembrane protein 64 2.01023
AHI1 Abelson helper integration site 1 2.00724

decreased expression

Symbol Name Standardized Value
ZNF200 zinc finger protein 200 -3.09377
RFC5 replication factor C (activator 1) 5, 36.5kDa -3.09377
RXRB retinoid X receptor, beta -3.09377
PNPO pyridoxamine 5'-phosphate oxidase -3.09377
CAMTA2 calmodulin binding transcription activator 2 -3.09377
CP ceruloplasmin (ferroxidase) -3.09377
CD37 CD37 molecule -3.09377
ANKRD24 ankyrin repeat domain 24 -3.09377
GPR39 G protein-coupled receptor 39 -3.09377
PILRB paired immunoglobin-like type 2 receptor beta -2.96502
LCA5L Leber congenital amaurosis 5-like -2.96502
GLB1L galactosidase, beta 1-like -2.96502
DNAI1 dynein, axonemal, intermediate chain 1 -2.96502
COL6A6 collagen, type VI, alpha 6 -2.96502
NEK5 NIMA-related kinase 5 -2.96502
BRI3 brain protein I3 -2.96502
PROZ protein Z, vitamin K-dependent plasma glycoprotein -2.96502
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 -2.96502
RAB3D RAB3D, member RAS oncogene family -2.96502
NRN1L neuritin 1-like -2.96502
ZNF687 zinc finger protein 687 -2.96502
MAPK13 mitogen-activated protein kinase 13 -2.96502
RBMS2 RNA binding motif, single stranded interacting protein 2 -2.96502
SSPN sarcospan -2.96502
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -2.96502
TGFB2 transforming growth factor, beta 2 -2.96502
RBM3 RNA binding motif (RNP1, RRM) protein 3 -2.96502
ZNF468 zinc finger protein 468 -2.96502
DCBLD1 discoidin, CUB and LCCL domain containing 1 -2.96502
PRODH proline dehydrogenase (oxidase) 1 -2.96502
TDRD5 tudor domain containing 5 -2.96502
FSCN3 fascin actin-bundling protein 3, testicular -2.96502
LMO2 LIM domain only 2 (rhombotin-like 1) -2.96502
CDH9 cadherin 9, type 2 (T1-cadherin) -2.96502
FGF20 fibroblast growth factor 20 -2.96502
SOX9 SRY (sex determining region Y)-box 9 -2.96502
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 -2.96502
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -2.96502
IZUMO1 izumo sperm-egg fusion 1 -2.96502
ISOC2 isochorismatase domain containing 2 -2.96502
TRIB3 tribbles pseudokinase 3 -2.96502
TGFBI transforming growth factor, beta-induced, 68kDa -2.96502
FAM20C family with sequence similarity 20, member C -2.96502
MAPK6 mitogen-activated protein kinase 6 -2.96502
ZDHHC1 zinc finger, DHHC-type containing 1 -2.96502
KLK10 kallikrein-related peptidase 10 -2.96502
MYO15A myosin XVA -2.96502
B9D2 B9 protein domain 2 -2.96502
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -2.96502
CLEC4A C-type lectin domain family 4, member A -2.96502
DCX doublecortin -2.96502
CCDC200 coiled-coil domain containing 200 -2.96502
RAMACL RNA guanine-7 methyltransferase activating subunit like -2.96502
CRIPTO3 cripto, EGF-CFC family member 3 -2.96502
ZNG1C Zn regulated GTPase metalloprotein activator 1C -2.96502
FAM151A family with sequence similarity 151, member A -2.96502
TMEM255B transmembrane protein 255B -2.96502
FAAH fatty acid amide hydrolase -2.96502
C2ORF72 chromosome 2 open reading frame 72 -2.96502
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 -2.96502
C12ORF60 chromosome 12 open reading frame 60 -2.96502
DAPK1 death-associated protein kinase 1 -2.96502
CDHR2 cadherin-related family member 2 -2.96502
HPD 4-hydroxyphenylpyruvate dioxygenase -2.96502
ARID1A AT rich interactive domain 1A (SWI-like) -2.96502
STX1A syntaxin 1A (brain) -2.96502
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3 -2.96502
C9ORF43 chromosome 9 open reading frame 43 -2.96502
ZNF543 zinc finger protein 543 -2.96502
MFF mitochondrial fission factor -2.95888
MBLAC2 metallo-beta-lactamase domain containing 2 -2.95597
CBARP CACN subunit beta associated regulatory protein -2.95597
CFLAR CASP8 and FADD-like apoptosis regulator -2.95597
KBTBD8 kelch repeat and BTB (POZ) domain containing 8 -2.94773
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -2.94639
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 -2.885
ZNF579 zinc finger protein 579 -2.885
BRD7 bromodomain containing 7 -2.85163
GTPBP6 GTP binding protein 6 (putative) -2.74472
RAB23 RAB23, member RAS oncogene family -2.71895
COX15 cytochrome c oxidase assembly homolog 15 (yeast) -2.66694
CHTOP chromatin target of PRMT1 -2.6661
CTPS1 CTP synthase 1 -2.65631
SFXN2 sideroflexin 2 -2.62858
OXLD1 oxidoreductase-like domain containing 1 -2.59444
CENPVL3 centromere protein V like 3 -2.59225
PGAM5 phosphoglycerate mutase family member 5 -2.55382
MACROH2A1 macroH2A.1 histone -2.52387
PABPC5 poly(A) binding protein, cytoplasmic 5 -2.51912
USP30 ubiquitin specific peptidase 30 -2.51912
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 -2.51912
DNAAF3 dynein, axonemal, assembly factor 3 -2.51912
PDE1A phosphodiesterase 1A, calmodulin-dependent -2.47786
RIOX2 ribosomal oxygenase 2 -2.47786
KRTDAP keratinocyte differentiation-associated protein -2.47786
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae) -2.47786
CLIC6 chloride intracellular channel 6 -2.45649
ZCCHC3 zinc finger, CCHC domain containing 3 -2.44158
TYW5 tRNA-yW synthesizing protein 5 -2.4393
MRPL11 mitochondrial ribosomal protein L11 -2.4393
INAVA innate immunity activator -2.4393
CLMP CXADR-like membrane protein -2.43903
GSDMB gasdermin B -2.42149
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.40958
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) -2.40882
XKR9 XK, Kell blood group complex subunit-related family, member 9 -2.40882
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.40882
PNKD paroxysmal nonkinesigenic dyskinesia -2.3937
MALL mal, T-cell differentiation protein-like -2.38837
ZNF485 zinc finger protein 485 -2.38837
ZNF587 zinc finger protein 587 -2.38668
TRIM25 tripartite motif containing 25 -2.38213
LINC02983 long intergenic non-protein coding RNA 2983 -2.31543
ZNF892 zinc finger protein 892 -2.31543
XKR6 XK, Kell blood group complex subunit-related family, member 6 -2.31398
RPS13 ribosomal protein S13 -2.31398
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa -2.2851
CEP120 centrosomal protein 120kDa -2.27988
FAM184A family with sequence similarity 184, member A -2.27988
STX1B syntaxin 1B -2.27929
FYCO1 FYVE and coiled-coil domain containing 1 -2.2437
MSRB3 methionine sulfoxide reductase B3 -2.21486
MRPS24 mitochondrial ribosomal protein S24 -2.20356
UNC45A unc-45 homolog A (C. elegans) -2.20299
TMEM230 transmembrane protein 230 -2.20299
EDC4 enhancer of mRNA decapping 4 -2.18092
NISCH nischarin -2.17581
IKZF1 IKAROS family zinc finger 1 (Ikaros) -2.17206
VCP valosin containing protein -2.16856
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.14634
C16ORF96 chromosome 16 open reading frame 96 -2.14459
PTPRR protein tyrosine phosphatase, receptor type, R -2.14459
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 -2.14067
TM7SF2 transmembrane 7 superfamily member 2 -2.13823
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -2.10651
CNBD2 cyclic nucleotide binding domain containing 2 -2.10642
MAPT microtubule-associated protein tau -2.10642
H2BC9 H2B clustered histone 9 -2.10642
FAM163B family with sequence similarity 163, member B -2.10642
CALM3 calmodulin 3 (phosphorylase kinase, delta) -2.10642
FABP7 fatty acid binding protein 7, brain -2.10642
ZNF764 zinc finger protein 764 -2.10642
SERTAD1 SERTA domain containing 1 -2.10642
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 -2.10642
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 -2.10642
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) -2.08911
KIAA1191 KIAA1191 -2.08849
CHD2 chromodomain helicase DNA binding protein 2 -2.07702
LRP1 low density lipoprotein receptor-related protein 1 -2.06896
KHDC4 KH domain containing 4, pre-mRNA splicing factor -2.06896
IRS4 insulin receptor substrate 4 -2.06228
CCDC136 coiled-coil domain containing 136 -2.0474
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -2.04448
ZSCAN22 zinc finger and SCAN domain containing 22 -2.04448
MFSD2B major facilitator superfamily domain containing 2B -2.04448
CA13 carbonic anhydrase XIII -2.04448
FRMPD4 FERM and PDZ domain containing 4 -2.04448
TIFA TRAF-interacting protein with forkhead-associated domain -2.04448
C12ORF42 chromosome 12 open reading frame 42 -2.04448
EXOSC3 exosome component 3 -2.02994
RPL34 ribosomal protein L34 -2.0193
PNKP polynucleotide kinase 3'-phosphatase -2.0193
VIRMA vir like m6A methyltransferase associated -2.0193
PLCB2 phospholipase C, beta 2 -2.01023
SIRPA signal-regulatory protein alpha -2.01023
FMO5 flavin containing monooxygenase 5 -2.01023
QRFPR pyroglutamylated RFamide peptide receptor -2.01023
WWOX WW domain containing oxidoreductase -2.01023
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -2.01023
GADD45G growth arrest and DNA-damage-inducible, gamma -2.01023
C10ORF143 chromosome 10 open reading frame 143 -2.01023
C19ORF44 chromosome 19 open reading frame 44 -2.01023
FBP1 fructose-1,6-bisphosphatase 1 -2.01023
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 -2.01023
ADPRH ADP-ribosylarginine hydrolase -2.01023
WBP2NL WBP2 N-terminal like -2.01023
NUCB2 nucleobindin 2 -2.01023
GREB1L growth regulation by estrogen in breast cancer-like -2.01023
SLITRK4 SLIT and NTRK-like family, member 4 -2.01023
TULP2 tubby like protein 2 -2.01023
ZNF174 zinc finger protein 174 -2.01023
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 -2.01023
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -2.01023
CCDC73 coiled-coil domain containing 73 -2.01023
SATL1 spermidine/spermine N1-acetyl transferase-like 1 -2.01023
HPSE heparanase -2.01023
PSMC3IP PSMC3 interacting protein -2.01023
NAT14 N-acetyltransferase 14 (GCN5-related, putative) -2.00392