SMAD2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SMAD family member 2|The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012] (NCBI Entrez Gene Database, 4087)
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Genes

394 genes differentially expressed following the SMAD2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TMCO2 transmembrane and coiled-coil domains 2 3.07061
NKAPL NFKB activating protein-like 3.07061
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 3.07061
CARD16 caspase recruitment domain family, member 16 3.07061
PI16 peptidase inhibitor 16 3.07061
MC4R melanocortin 4 receptor 3.07061
CELF6 CUGBP, Elav-like family member 6 3.07061
IL22RA1 interleukin 22 receptor, alpha 1 3.07061
TMEM176B transmembrane protein 176B 3.07061
TEX13A testis expressed 13A 3.07061
PDIA2 protein disulfide isomerase family A, member 2 3.07061
PCDHB7 protocadherin beta 7 3.07061
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 3.07061
INHBB inhibin, beta B 3.07061
VIT vitrin 3.07061
PCDHB11 protocadherin beta 11 3.07061
DMP1 dentin matrix acidic phosphoprotein 1 3.07061
PRB4 proline-rich protein BstNI subfamily 4 3.07061
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 3.07061
CD300LG CD300 molecule-like family member g 3.07061
KLF17 Kruppel-like factor 17 3.07061
KLHL35 kelch-like family member 35 3.07061
OR5P3 olfactory receptor, family 5, subfamily P, member 3 3.07061
TMPRSS11A transmembrane protease, serine 11A 3.07061
IFNA2 interferon, alpha 2 3.07061
TM4SF5 transmembrane 4 L six family member 5 3.07061
SSTR1 somatostatin receptor 1 3.07061
HORMAD1 HORMA domain containing 1 3.07061
MLN motilin 3.07061
HAS1 hyaluronan synthase 1 3.07061
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 3.07061
C1ORF146 chromosome 1 open reading frame 146 3.07061
UBA7 ubiquitin-like modifier activating enzyme 7 3.07061
RGPD3 RANBP2-like and GRIP domain containing 3 3.07061
NPIPA3 nuclear pore complex interacting protein family, member A3 3.07061
ICOS inducible T-cell co-stimulator 3.07061
OR51T1 olfactory receptor, family 51, subfamily T, member 1 3.07061
OXT oxytocin/neurophysin I prepropeptide 3.07061
ATOH8 atonal homolog 8 (Drosophila) 3.07061
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) 3.07061
PECAM1 platelet/endothelial cell adhesion molecule 1 3.07061
PGBDF plakoglobin binding and degradation factor 3.07061
NCF4 neutrophil cytosolic factor 4, 40kDa 3.07061
CRISP1 cysteine-rich secretory protein 1 3.07061
SIRPB1 signal-regulatory protein beta 1 3.07061
AADACL4 arylacetamide deacetylase-like 4 3.07061
MUC5B mucin 5B, oligomeric mucus/gel-forming 3.07061
CSTL1 cystatin-like 1 3.07061
ASB12 ankyrin repeat and SOCS box containing 12 3.07061
SLC30A4 solute carrier family 30 (zinc transporter), member 4 3.07061
NEU4 sialidase 4 3.07061
GPR22 G protein-coupled receptor 22 3.07061
BMP5 bone morphogenetic protein 5 3.07061
GOLGA7B golgin A7 family, member B 3.07061
LOC124905976 uncharacterized LOC124905976 3.07061
CCN5 cellular communication network factor 5 3.07061
GASK1B golgi associated kinase 1B 3.07061
LHFPL6 LHFPL tetraspan subfamily member 6 3.07061
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 3.07061
TMEM275 transmembrane protein 275 3.07061
SELE selectin E 3.07061
ARX aristaless related homeobox 3.07061
ZAR1 zygote arrest 1 3.07061
GPR31 G protein-coupled receptor 31 3.07061
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 3.07061
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 3.07061
CCDC198 coiled-coil domain containing 198 3.07061
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 3.07061
SPMIP7 sperm microtubule inner protein 7 3.07061
EPCIP exosomal polycystin 1 interacting protein 3.07061
TBC1D3I TBC1 domain family member 3I 3.07061
RNF228 ring finger protein 228 3.07061
NHERF4 NHERF family PDZ scaffold protein 4 3.07061
SERTM2 serine rich and transmembrane domain containing 2 3.07061
H2AC19 H2A clustered histone 19 3.07061
SHOC1 shortage in chiasmata 1 3.07061
SPDYE9 speedy/RINGO cell cycle regulator family member E9 3.07061
SPATA46 spermatogenesis associated 46 3.07061
RTL9 retrotransposon Gag like 9 3.07061
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 3.07061
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 3.07061
ASB4 ankyrin repeat and SOCS box containing 4 3.07061
IL1RN interleukin 1 receptor antagonist 3.07061
LRRC3C leucine rich repeat containing 3C 3.07061
SAA1 serum amyloid A1 3.07061
C7ORF57 chromosome 7 open reading frame 57 3.07061
PABPC3 poly(A) binding protein, cytoplasmic 3 3.07061
S100G S100 calcium binding protein G 3.07061
CCR4 chemokine (C-C motif) receptor 4 3.07061
KCNT1 potassium channel, sodium activated subfamily T, member 1 3.07061
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 3.07061
SH3TC1 SH3 domain and tetratricopeptide repeats 1 3.07061
AWAT1 acyl-CoA wax alcohol acyltransferase 1 3.07061
FMR1NB fragile X mental retardation 1 neighbor 3.07061
GDF9 growth differentiation factor 9 3.07061
SPATA25 spermatogenesis associated 25 3.07061
ATP4B ATPase, H+/K+ exchanging, beta polypeptide 3.07061
DYNLRB2 dynein, light chain, roadblock-type 2 3.07061
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 3.07061
GATA1 GATA binding protein 1 (globin transcription factor 1) 3.07061
GATA2 GATA binding protein 2 3.07061
GATA4 GATA binding protein 4 3.07061
CLEC6A C-type lectin domain family 6, member A 3.07061
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 3.07061
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 3.07061
DLK2 delta-like 2 homolog (Drosophila) 3.07061
TLR7 toll-like receptor 7 3.07061
NKX6-3 NK6 homeobox 3 3.07061
NOBOX NOBOX oogenesis homeobox 3.07061
EDN2 endothelin 2 3.07061
C18ORF63 chromosome 18 open reading frame 63 3.07061
ADGRA1 adhesion G protein-coupled receptor A1 3.07061
DEFB107B defensin, beta 107B 3.07061
NOX1 NADPH oxidase 1 3.07061
NR5A1 nuclear receptor subfamily 5, group A, member 1 3.07061
C2ORF66 chromosome 2 open reading frame 66 3.07061
PGR progesterone receptor 3.07061
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 3.07061
LRRC46 leucine rich repeat containing 46 3.07061
LY6G6D lymphocyte antigen 6 complex, locus G6D 3.07061
SMYD1 SET and MYND domain containing 1 3.07061
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 3.07061
GSC2 goosecoid homeobox 2 3.07061
LRRC25 leucine rich repeat containing 25 3.07061
PENK proenkephalin 3.07061
PCDHGB5 protocadherin gamma subfamily B, 5 3.07061
MOS v-mos Moloney murine sarcoma viral oncogene homolog 3.07061
CALHM1 calcium homeostasis modulator 1 3.07061
GSTA2 glutathione S-transferase alpha 2 3.07061
ISL2 ISL LIM homeobox 2 3.07061
TEX19 testis expressed 19 3.07061
SLC22A24 solute carrier family 22, member 24 3.07061
SAMD9 sterile alpha motif domain containing 9 3.07061
KLK15 kallikrein-related peptidase 15 3.07061
C20ORF144 chromosome 20 open reading frame 144 3.07061
LRRC15 leucine rich repeat containing 15 3.07061
MUC7 mucin 7, secreted 3.07061
SAMD5 sterile alpha motif domain containing 5 3.07061
URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase 3.07061
C22ORF42 chromosome 22 open reading frame 42 3.07061
SLC36A3 solute carrier family 36, member 3 3.07061
AICDA activation-induced cytidine deaminase 3.07061
ZC3H11D zinc finger CCCH-type containing 11D 3.07061
MAMLD1 mastermind-like domain containing 1 3.07061
MAB21L3 mab-21-like 3 (C. elegans) 3.07061
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 3.07061
MAGEE2 melanoma antigen family E2 3.07061
ZNF735 zinc finger protein 735 3.07061
LENEP lens epithelial protein 3.07061
FZD1 frizzled class receptor 1 3.07061
CPN2 carboxypeptidase N, polypeptide 2 3.07061
PARP15 poly (ADP-ribose) polymerase family, member 15 3.07061
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 3.07061
HRG histidine-rich glycoprotein 3.07061
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 3.07061
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 3.07061
CD34 CD34 molecule 3.07061
OR14A2 olfactory receptor, family 14, subfamily A, member 2 3.07061
ANKRD30A ankyrin repeat domain 30A 3.07061
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 3.07061
TEX26 testis expressed 26 3.07061
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 3.07061
AOC1 amine oxidase, copper containing 1 3.07061
LAMB3 laminin, beta 3 3.07061
CCDC87 coiled-coil domain containing 87 3.07061
SLC51B solute carrier family 51, beta subunit 3.07061
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 3.07061
SLITRK2 SLIT and NTRK-like family, member 2 3.07061
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 3.07061
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 3.07061
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 3.07061
GJB6 gap junction protein, beta 6, 30kDa 3.07061
PPP1R27 protein phosphatase 1, regulatory subunit 27 3.07061
ITPKA inositol-trisphosphate 3-kinase A 3.07061
RXRG retinoid X receptor, gamma 3.07061
TGM1 transglutaminase 1 2.9869
RAI2 retinoic acid induced 2 2.9869
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 2.9869
FBXO43 F-box protein 43 2.96535
WDR91 WD repeat domain 91 2.86407
DALRD3 DALR anticodon binding domain containing 3 2.82422
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 2.61248
TBC1D15 TBC1 domain family, member 15 2.608
CCNA2 cyclin A2 2.51859
MYO1B myosin IB 2.50713
KCNK2 potassium channel, two pore domain subfamily K, member 2 2.50713
PCGF5 polycomb group ring finger 5 2.50434
GALR1 galanin receptor 1 2.49911
NPSR1 neuropeptide S receptor 1 2.45805
KAT7 K(lysine) acetyltransferase 7 2.44742
PRKCA protein kinase C, alpha 2.44742
HEBP1 heme binding protein 1 2.43351
DUSP12 dual specificity phosphatase 12 2.4261
SF3A3 splicing factor 3a, subunit 3, 60kDa 2.39412
FNDC3A fibronectin type III domain containing 3A 2.37155
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 2.37056
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.37015
HSPB1 heat shock 27kDa protein 1 2.36899
DHRS13 dehydrogenase/reductase (SDR family) member 13 2.36384
TACR1 tachykinin receptor 1 2.34906
SH3GL3 SH3-domain GRB2-like 3 2.34906
PRTG protogenin 2.34839
MSH5 mutS homolog 5 2.33783
SLC6A16 solute carrier family 6, member 16 2.33493
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 2.32598
CDYL chromodomain protein, Y-like 2.32202
ATF6B activating transcription factor 6 beta 2.30894
FHIP1A FHF complex subunit HOOK interacting protein 1A 2.30681
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 2.30628
ADISSP adipose secreted signaling protein 2.28874
STARD5 StAR-related lipid transfer (START) domain containing 5 2.28221
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 2.28221
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 2.26701
ARC activity-regulated cytoskeleton-associated protein 2.26444
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 2.22645
RGS17 regulator of G-protein signaling 17 2.2249
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 2.20957
CLBA1 clathrin binding box of aftiphilin containing 1 2.20276
CCBE1 collagen and calcium binding EGF domains 1 2.19693
IL20RA interleukin 20 receptor, alpha 2.19001
C22ORF15 chromosome 22 open reading frame 15 2.18519
SLIT2 slit homolog 2 (Drosophila) 2.18519
TMEM132B transmembrane protein 132B 2.17145
CBX6 chromobox homolog 6 2.1701
USP3 ubiquitin specific peptidase 3 2.16884
ALKAL2 ALK and LTK ligand 2 2.16563
PACRGL PARK2 co-regulated-like 2.16563
TAC3 tachykinin 3 2.16563
ZBTB17 zinc finger and BTB domain containing 17 2.16563
NBPF20 neuroblastoma breakpoint family, member 20 2.14628
ZC2HC1A zinc finger, C2HC-type containing 1A 2.14078
TSBP1 testis expressed basic protein 1 2.13207
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10 2.13207
DENND1C DENN/MADD domain containing 1C 2.12382
PTPRG protein tyrosine phosphatase, receptor type, G 2.12018
GIN1 gypsy retrotransposon integrase 1 2.11729
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 2.11729
WTIP Wilms tumor 1 interacting protein 2.09509
DAGLB diacylglycerol lipase, beta 2.09509
ZNF649 zinc finger protein 649 2.08465
ENDOG endonuclease G 2.08465
ATL2 atlastin GTPase 2 2.05845
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.05831
TGFBR1 transforming growth factor, beta receptor 1 2.03044
PRKACB protein kinase, cAMP-dependent, catalytic, beta 2.01285
ZNF214 zinc finger protein 214 2.0109
RPP14 ribonuclease P/MRP 14kDa subunit 2.00836
EIF6 eukaryotic translation initiation factor 6 2.00836
PADI3 peptidyl arginine deiminase, type III 2.00836
RHOF ras homolog family member F (in filopodia) 2.00836
CDK7 cyclin-dependent kinase 7 2.00331
SHD Src homology 2 domain containing transforming protein D 2.00078

decreased expression

Symbol Name Standardized Value
CCR9 chemokine (C-C motif) receptor 9 -3.07061
SLITRK1 SLIT and NTRK-like family, member 1 -3.07061
PARN poly(A)-specific ribonuclease -3.07061
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 -3.07061
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) -3.07061
ING5 inhibitor of growth family, member 5 -3.07061
KCNK3 potassium channel, two pore domain subfamily K, member 3 -3.07061
AMIGO1 adhesion molecule with Ig-like domain 1 -3.07061
TMPRSS6 transmembrane protease, serine 6 -3.07061
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -3.07061
CD53 CD53 molecule -3.07061
IDO2 indoleamine 2,3-dioxygenase 2 -3.07061
BCL10 B-cell CLL/lymphoma 10 -3.07061
LOC105378220 macrophage receptor MARCO-like -3.07061
SAA2 serum amyloid A2 -3.07061
EMCN endomucin -3.07061
FAM161B family with sequence similarity 161, member B -3.07061
PCDHGA11 protocadherin gamma subfamily A, 11 -3.07061
PIWIL1 piwi-like RNA-mediated gene silencing 1 -3.07061
ATMIN ATM interactor -3.07061
CD160 CD160 molecule -3.07061
LEFTY2 left-right determination factor 2 -3.07061
CALD1 caldesmon 1 -3.07061
TAL2 T-cell acute lymphocytic leukemia 2 -3.07061
AMDHD1 amidohydrolase domain containing 1 -3.07061
GOLGA6L4 golgin A6 family-like 4 -3.07061
ACTA1 actin, alpha 1, skeletal muscle -3.07061
CA5A carbonic anhydrase VA, mitochondrial -3.07061
DND1 DND microRNA-mediated repression inhibitor 1 -3.07061
GPR179 G protein-coupled receptor 179 -3.07061
TEKTIP1 tektin bundle interacting protein 1 -3.07061
LGALS4 lectin, galactoside-binding, soluble, 4 -3.07061
HMGB3 high mobility group box 3 -3.07061
GSTT4 glutathione S-transferase theta 4 -3.07061
CPHXL cytoplasmic polyadenylated homeobox like -3.07061
IHO1 interactor of HORMAD1 1 -3.07061
HCRT hypocretin (orexin) neuropeptide precursor -3.07061
WSCD2 WSC domain containing 2 -3.07061
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 -3.07061
HNF4A hepatocyte nuclear factor 4, alpha -3.07061
COL19A1 collagen, type XIX, alpha 1 -3.07061
BCO1 beta-carotene oxygenase 1 -3.07061
SLC22A17 solute carrier family 22, member 17 -3.07061
CPA6 carboxypeptidase A6 -3.06623
INTS12 integrator complex subunit 12 -3.02842
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -2.98694
ST14 suppression of tumorigenicity 14 (colon carcinoma) -2.92854
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -2.89257
SMAP2 small ArfGAP2 -2.87828
THBS2 thrombospondin 2 -2.85201
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific -2.82119
ZBTB14 zinc finger and BTB domain containing 14 -2.82119
TTC39C tetratricopeptide repeat domain 39C -2.79654
DACT1 dishevelled-binding antagonist of beta-catenin 1 -2.76209
RAB27A RAB27A, member RAS oncogene family -2.7611
ABLIM1 actin binding LIM protein 1 -2.7067
LYPD3 LY6/PLAUR domain containing 3 -2.69785
STXBP4 syntaxin binding protein 4 -2.68485
MAP2K6 mitogen-activated protein kinase kinase 6 -2.65885
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) -2.6551
ARHGAP19 Rho GTPase activating protein 19 -2.64231
PAM peptidylglycine alpha-amidating monooxygenase -2.58515
PTPN9 protein tyrosine phosphatase, non-receptor type 9 -2.57385
DOCK1 dedicator of cytokinesis 1 -2.56556
SMAD2 SMAD family member 2 -2.55811
MAP1B microtubule-associated protein 1B -2.54298
PROKR1 prokineticin receptor 1 -2.54154
RUMY3 RUMY family member 3 -2.53708
BRICD5 BRICHOS domain containing 5 -2.53708
MRPL53 mitochondrial ribosomal protein L53 -2.53708
GPC6 glypican 6 -2.53417
MGAT4C MGAT4 family, member C -2.52913
INO80 INO80 complex subunit -2.52548
CYTH2 cytohesin 2 -2.51644
BOLL boule-like RNA-binding protein -2.50072
PUS3 pseudouridylate synthase 3 -2.47789
RAD23B RAD23 homolog B (S. cerevisiae) -2.46923
TFCP2 transcription factor CP2 -2.41509
RAB11FIP3 RAB11 family interacting protein 3 (class II) -2.37979
CCDC57 coiled-coil domain containing 57 -2.36808
NOL7 nucleolar protein 7, 27kDa -2.36808
GAL3ST3 galactose-3-O-sulfotransferase 3 -2.36264
YY1 YY1 transcription factor -2.34839
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 -2.34839
AGXT2 alanine--glyoxylate aminotransferase 2 -2.34839
OVGP1 oviductal glycoprotein 1, 120kDa -2.34839
CNTD1 cyclin N-terminal domain containing 1 -2.34839
CRACR2B calcium release activated channel regulator 2B -2.34069
RYR2 ryanodine receptor 2 (cardiac) -2.32202
IQSEC2 IQ motif and Sec7 domain 2 -2.30894
LEFTY1 left-right determination factor 1 -2.30232
TMSB10 thymosin beta 10 -2.29142
NPAP1 nuclear pore associated protein 1 -2.28221
TBX22 T-box 22 -2.28221
CCL25 chemokine (C-C motif) ligand 25 -2.28221
SNX30 sorting nexin family member 30 -2.28221
SPIN1 spindlin 1 -2.281
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) -2.27295
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.26404
CDC20 cell division cycle 20 -2.26156
GRAMD1C GRAM domain containing 1C -2.26156
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 -2.26021
MAPK9 mitogen-activated protein kinase 9 -2.23513
FKBP10 FK506 binding protein 10, 65 kDa -2.23301
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -2.21493
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -2.18133
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase -2.16647
OXLD1 oxidoreductase-like domain containing 1 -2.16563
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase -2.15466
TPCN1 two pore segment channel 1 -2.15136
SYCP2L synaptonemal complex protein 2-like -2.13821
SLC30A6 solute carrier family 30 (zinc transporter), member 6 -2.13821
PRDM14 PR domain containing 14 -2.13207
GPC4 glypican 4 -2.12611
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 -2.09509
H3C12 H3 clustered histone 12 -2.09509
HBS1L HBS1-like translational GTPase -2.0894
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa -2.08465
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -2.0811
CD276 CD276 molecule -2.0728
FUOM fucose mutarotase -2.07253
SNTG1 syntrophin, gamma 1 -2.07147
PLPPR5 phospholipid phosphatase related 5 -2.07147
CIAO2A cytosolic iron-sulfur assembly component 2A -2.06147
PPP1R21 protein phosphatase 1, regulatory subunit 21 -2.05845
TMC4 transmembrane channel-like 4 -2.05023
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 -2.04207
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -2.04171
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 -2.04171
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor -2.04171
FNBP1L formin binding protein 1-like -2.03886
HDAC2 histone deacetylase 2 -2.03751
PRKCI protein kinase C, iota -2.03689
ZCCHC17 zinc finger, CCHC domain containing 17 -2.02758
NSMCE3 NSE3 homolog, SMC5-SMC6 complex component -2.02168
USP31 ubiquitin specific peptidase 31 -2.01941
GADD45G growth arrest and DNA-damage-inducible, gamma -2.01285
WIPF2 WAS/WASL interacting protein family, member 2 -2.00836
CSDC2 cold shock domain containing C2, RNA binding -2.00836
KLHL10 kelch-like family member 10 -2.00836
PGLYRP1 peptidoglycan recognition protein 1 -2.00836
NUP214 nucleoporin 214kDa -2.00836