| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | SMAD family member 3|The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009] (NCBI Entrez Gene Database, 4088) |
| External Link | https://ncbi.nlm.nih.gov/gene/4088 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the SMAD3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| APOD | apolipoprotein D | 0.00812119 |
| XIC | X chromosome inactivation center | 0.00801915 |
| MMP12 | matrix metallopeptidase 12 | 0.0078289 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00763095 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00730209 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00719233 |
| DENND2D | DENN/MADD domain containing 2D | 0.0071296 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00712594 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00696312 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00690233 |
| IL2RG | interleukin 2 receptor, gamma | 0.00686251 |
| MAGEA3 | melanoma antigen family A3 | 0.00666534 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00666412 |
| LCN2 | lipocalin 2 | 0.00664351 |
| NRN1 | neuritin 1 | 0.00650622 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00638106 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | 0.0063323 |
| PLTP | phospholipid transfer protein | 0.00626217 |
| ATF3 | activating transcription factor 3 | 0.00622296 |
| MAGEA12 | melanoma antigen family A12 | 0.00612118 |
| SERINC5 | serine incorporator 5 | 0.00610441 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.00608931 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00596818 |
| ARG1 | arginase 1 | 0.00596157 |
| RGCC | regulator of cell cycle | 0.00592321 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00590653 |
| EPCAM | epithelial cell adhesion molecule | 0.00589323 |
| LY75 | lymphocyte antigen 75 | 0.00582594 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.0058208 |
| TMEM176B | transmembrane protein 176B | 0.00580375 |
| TMEM176A | transmembrane protein 176A | 0.00575378 |
| TOX3 | TOX high mobility group box family member 3 | 0.00571714 |
| IPO13 | importin 13 | 0.00571007 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00567735 |
| PROM1 | prominin 1 | 0.00562914 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00562483 |
| CCNF | cyclin F | 0.00560434 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00557067 |
| MMP8 | matrix metallopeptidase 8 | 0.00555244 |
| COL1A2 | collagen, type I, alpha 2 | 0.00549992 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00541798 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0054074 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.0054033 |
| FCGBP | Fc fragment of IgG binding protein | 0.00539845 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.00538806 |
| A2M | alpha-2-macroglobulin | 0.00537535 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.0053601 |
| CENPU | centromere protein U | 0.00535403 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | 0.00534054 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 | 0.00528278 |
| PDHX | pyruvate dehydrogenase complex, component X | 0.00527075 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.00525876 |
| EFNB2 | ephrin-B2 | 0.00522951 |
| DMD | dystrophin | 0.00517338 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00515753 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00513081 |
| STK39 | serine threonine kinase 39 | 0.00511288 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00511041 |
| CD84 | CD84 molecule | 0.00510771 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00509055 |
| CALML4 | calmodulin-like 4 | 0.00502766 |
| EGR1 | early growth response 1 | 0.00501271 |
| PRTN3 | proteinase 3 | 0.00500542 |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.00496434 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00495458 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) | 0.0049274 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00491905 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00490327 |
| ZG16 | zymogen granule protein 16 | 0.00489785 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00489489 |
| MUC4 | mucin 4, cell surface associated | 0.00488192 |
| TNC | tenascin C | 0.00487635 |
| FGL2 | fibrinogen-like 2 | 0.00487344 |
| CLDN8 | claudin 8 | 0.00485882 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00483527 |
| RAB25 | RAB25, member RAS oncogene family | 0.00480074 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00479947 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00479694 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00478664 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.00478422 |
| CHPT1 | choline phosphotransferase 1 | 0.00477188 |
| CTSG | cathepsin G | 0.00475899 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00474308 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.00473444 |
| NOX1 | NADPH oxidase 1 | 0.00470009 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 0.00469367 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.00469188 |
| COG7 | component of oligomeric golgi complex 7 | 0.00468699 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.00468413 |
| FOXC1 | forkhead box C1 | 0.00465968 |
| SSX1 | synovial sarcoma, X breakpoint 1 | 0.00465267 |
| ADCY1 | adenylate cyclase 1 (brain) | 0.00464572 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0046425 |
| BSPRY | B-box and SPRY domain containing | 0.00463435 |
| FZD5 | frizzled class receptor 5 | 0.00461202 |
| NCALD | neurocalcin delta | 0.00460585 |
| BPI | bactericidal/permeability-increasing protein | 0.00459563 |
| PURA | purine-rich element binding protein A | 0.00458498 |
| DCT | dopachrome tautomerase | 0.00457949 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00457001 |
| CTSS | cathepsin S | 0.00455961 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0045516 |
| CTSK | cathepsin K | 0.00454698 |
| CD200 | CD200 molecule | 0.00454359 |
| COBL | cordon-bleu WH2 repeat protein | 0.00453942 |
| TMEM168 | transmembrane protein 168 | 0.00453599 |
| SATB2 | SATB homeobox 2 | 0.00451432 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00451281 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00447685 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00446876 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | 0.00446287 |
| MAGEB2 | melanoma antigen family B2 | 0.00444544 |
| DHDDS | dehydrodolichyl diphosphate synthase | 0.00442859 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.00440595 |
| KLF6 | Kruppel-like factor 6 | 0.0044051 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | 0.00438758 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.0043858 |
| CFAP298 | cilia and flagella associated protein 298 | 0.00438503 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.00436861 |
| MED22 | mediator complex subunit 22 | 0.0043205 |
| AZU1 | azurocidin 1 | 0.0043202 |
| GPM6B | glycoprotein M6B | 0.00431788 |
| C4ORF19 | chromosome 4 open reading frame 19 | 0.0043038 |
| JUN | jun proto-oncogene | 0.00429354 |
| COL21A1 | collagen, type XXI, alpha 1 | 0.00429038 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.00427764 |
| IQCG | IQ motif containing G | 0.00427661 |
| TXNIP | thioredoxin interacting protein | 0.00425926 |
| CD177 | CD177 molecule | 0.00425206 |
| NOTCH3 | notch 3 | 0.00425147 |
| IRS2 | insulin receptor substrate 2 | 0.00425001 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00423025 |
| APIP | APAF1 interacting protein | 0.00421082 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00420934 |
| GRB14 | growth factor receptor-bound protein 14 | 0.00420676 |
| ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | 0.00420291 |
| TFF1 | trefoil factor 1 | 0.00420157 |
| CLCA1 | chloride channel accessory 1 | 0.0041989 |
| ELANE | elastase, neutrophil expressed | 0.00418883 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00417536 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0041701 |
| ESRP2 | epithelial splicing regulatory protein 2 | 0.00416339 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.00416223 |
| STC1 | stanniocalcin 1 | 0.00415996 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.00414836 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0041384 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 0.00413736 |
| EHF | ets homologous factor | 0.00413678 |
| MCOLN1 | mucolipin 1 | 0.00413106 |
| PEG10 | paternally expressed 10 | 0.00412147 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.00411442 |
| CERT1 | ceramide transporter 1 | 0.00411196 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0041106 |
| MYO1D | myosin ID | 0.00410584 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.00408267 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | 0.00408135 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00408082 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.00408062 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00407197 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | 0.00405908 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | 0.00405317 |
| RTN3 | reticulon 3 | 0.00405098 |
| TMEM231 | transmembrane protein 231 | 0.00404923 |
| INSM1 | insulinoma-associated 1 | 0.00404067 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | 0.00403676 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00401397 |
| FOXG1 | forkhead box G1 | 0.00400451 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.00399379 |
| LAMA4 | laminin, alpha 4 | 0.00396934 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00396336 |
| PER2 | period circadian clock 2 | 0.00395554 |
| STAG3 | stromal antigen 3 | 0.00395162 |
| AOC1 | amine oxidase, copper containing 1 | 0.0039472 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.00394685 |
| STXBP2 | syntaxin binding protein 2 | 0.00393478 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | 0.00392665 |
| ZBBX | zinc finger, B-box domain containing | 0.00391786 |
| TOX | thymocyte selection-associated high mobility group box | 0.00390611 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00390204 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00389468 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00388079 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | 0.00387861 |
| KIAA0226L | KIAA0226-like | 0.00386719 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | 0.00385661 |
| TBC1D31 | TBC1 domain family, member 31 | 0.0038524 |
| GTPBP8 | GTP-binding protein 8 (putative) | 0.0038489 |
| DCAF16 | DDB1 and CUL4 associated factor 16 | 0.00384134 |
| PRSS21 | protease, serine, 21 (testisin) | 0.00383875 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein | 0.00382624 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.00382566 |
| SH2D1A | SH2 domain containing 1A | 0.00382214 |
| FAM46C | family with sequence similarity 46, member C | 0.00381564 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00379925 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00379404 |
| RCAN1 | regulator of calcineurin 1 | 0.00378979 |
| FABP1 | fatty acid binding protein 1, liver | 0.00378622 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | 0.00378283 |
| SLIT1 | slit homolog 1 (Drosophila) | 0.00376634 |
| SPAG1 | sperm associated antigen 1 | 0.00376325 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.00375661 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.00375262 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.00374469 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | 0.00374362 |
| COG5 | component of oligomeric golgi complex 5 | 0.00372979 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00371558 |
| PTGFR | prostaglandin F receptor (FP) | 0.00371248 |
| ICA1 | islet cell autoantigen 1, 69kDa | 0.003703 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 | 0.00370197 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.00369982 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | 0.00369919 |
| FTO | fat mass and obesity associated | 0.00369766 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.0036942 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.00368746 |
| VIL1 | villin 1 | 0.00368484 |
| HAL | histidine ammonia-lyase | 0.00368102 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00366912 |
| KIF14 | kinesin family member 14 | 0.00366429 |
| CCDC86 | coiled-coil domain containing 86 | 0.00365925 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | 0.00364709 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00364385 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00364003 |
| PLPP3 | phospholipid phosphatase 3 | 0.00362444 |
| ASRGL1 | asparaginase like 1 | 0.00360935 |
| CAPN9 | calpain 9 | 0.00360889 |
| SHTN1 | shootin 1 | 0.00360325 |
| MUC16 | mucin 16, cell surface associated | 0.00359211 |
| SLAMF8 | SLAM family member 8 | 0.00358628 |
| TRIB3 | tribbles pseudokinase 3 | 0.00358349 |
| FOXJ1 | forkhead box J1 | 0.00357294 |
| ELAVL4 | ELAV like neuron-specific RNA binding protein 4 | 0.00356708 |
| PCGF1 | polycomb group ring finger 1 | 0.00356316 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.00355784 |
| CD1A | CD1a molecule | 0.00355634 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00355252 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.00354649 |
| PGLYRP1 | peptidoglycan recognition protein 1 | 0.00354265 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00354219 |
| MSX1 | msh homeobox 1 | 0.00354163 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.00354093 |
| RNF130 | ring finger protein 130 | 0.00353893 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00353453 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.00352713 |
| RAD21 | RAD21 homolog (S. pombe) | 0.00352612 |
| CDC16 | cell division cycle 16 | 0.00352578 |
| TEX2 | testis expressed 2 | 0.00351617 |
| AIM2 | absent in melanoma 2 | 0.00350941 |
| CAMP | cathelicidin antimicrobial peptide | 0.00349113 |
| CCL17 | chemokine (C-C motif) ligand 17 | 0.00348646 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00348604 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | -0.0185867 |
| HOPX | HOP homeobox | -0.0135796 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0114205 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.010775 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0105173 |
| ABLIM1 | actin binding LIM protein 1 | -0.00989614 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00965573 |
| CLU | clusterin | -0.00960414 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00959115 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00959033 |
| CD44 | CD44 molecule (Indian blood group) | -0.00922666 |
| ADIRF | adipogenesis regulatory factor | -0.00887855 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00857782 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00852729 |
| NELL2 | NEL-like 2 (chicken) | -0.00845448 |
| CLIC3 | chloride intracellular channel 3 | -0.0083522 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00830267 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00823197 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00813837 |
| TUBB6 | tubulin, beta 6 class V | -0.00797275 |
| TBX3 | T-box 3 | -0.0079727 |
| MXRA7 | matrix-remodelling associated 7 | -0.00788219 |
| TPD52L2 | tumor protein D52-like 2 | -0.00777237 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00765698 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00755547 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | -0.00734847 |
| FHL1 | four and a half LIM domains 1 | -0.00730674 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00729632 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00728864 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00725296 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00724398 |
| KRT7 | keratin 7, type II | -0.00719059 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00717278 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00716418 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00715788 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00711083 |
| CD9 | CD9 molecule | -0.00706266 |
| SYNM | synemin, intermediate filament protein | -0.00697593 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00693209 |
| CFI | complement factor I | -0.00683499 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00677486 |
| KRT13 | keratin 13, type I | -0.00675065 |
| MIR22HG | MIR22 host gene | -0.00668419 |
| GPX3 | glutathione peroxidase 3 | -0.0066446 |
| PDGFC | platelet derived growth factor C | -0.00660454 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00659018 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00653126 |
| FBXO21 | F-box protein 21 | -0.00652071 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00646494 |
| CRYAB | crystallin, alpha B | -0.00644583 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.00643144 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00642072 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | -0.00640569 |
| TAGLN | transgelin | -0.00635184 |
| EPHA2 | EPH receptor A2 | -0.00632239 |
| STK10 | serine/threonine kinase 10 | -0.00631613 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00629298 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00626289 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -0.00622392 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00621802 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00621379 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00617954 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00617596 |
| KRT19 | keratin 19, type I | -0.00614749 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0061008 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.00609045 |
| CERK | ceramide kinase | -0.00606212 |
| CDC20 | cell division cycle 20 | -0.00606133 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00605717 |
| S100A2 | S100 calcium binding protein A2 | -0.00604568 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00604344 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00600411 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -0.00599273 |
| PKP1 | plakophilin 1 | -0.00596832 |
| RTN2 | reticulon 2 | -0.00593488 |
| HBB | hemoglobin, beta | -0.00593223 |
| ITGAV | integrin, alpha V | -0.00592715 |
| LBH | limb bud and heart development | -0.00592418 |
| MT1E | metallothionein 1E | -0.00592353 |
| CCN2 | cellular communication network factor 2 | -0.00587831 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00584278 |
| FBN2 | fibrillin 2 | -0.00583203 |
| RIN2 | Ras and Rab interactor 2 | -0.00582348 |
| PCP4 | Purkinje cell protein 4 | -0.00582144 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00581693 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00581521 |
| MMP7 | matrix metallopeptidase 7 | -0.00581013 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00577706 |
| WASF1 | WAS protein family, member 1 | -0.00574939 |
| SORD | sorbitol dehydrogenase | -0.00573515 |
| BTG2 | BTG family, member 2 | -0.00569568 |
| XYLT1 | xylosyltransferase I | -0.00567986 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00563445 |
| RHOBTB1 | Rho-related BTB domain containing 1 | -0.00563152 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00561279 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00561105 |
| GATA6 | GATA binding protein 6 | -0.00560683 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00560328 |
| CSK | c-src tyrosine kinase | -0.00559766 |
| IL1RN | interleukin 1 receptor antagonist | -0.00559349 |
| KLHL41 | kelch-like family member 41 | -0.00559152 |
| MYOT | myotilin | -0.0055897 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00557448 |
| ZNF532 | zinc finger protein 532 | -0.00555091 |
| LXN | latexin | -0.00554961 |
| CUX2 | cut-like homeobox 2 | -0.00553858 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.00553287 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00552522 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0055083 |
| MB | myoglobin | -0.00550037 |
| MSN | moesin | -0.0054909 |
| EMP3 | epithelial membrane protein 3 | -0.00547024 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00545824 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) | -0.0054562 |
| BMP2 | bone morphogenetic protein 2 | -0.00543568 |
| TGFB1 | transforming growth factor, beta 1 | -0.00542504 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00540045 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00537761 |
| JCAD | junctional cadherin 5 associated | -0.00537578 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00537511 |
| PRKD2 | protein kinase D2 | -0.00534948 |
| AXL | AXL receptor tyrosine kinase | -0.00533499 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00532901 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -0.00530602 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00529634 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00528651 |
| ANOS1 | anosmin 1 | -0.005278 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.00527696 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00526411 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00522997 |
| ECM1 | extracellular matrix protein 1 | -0.00522595 |
| SDC4 | syndecan 4 | -0.00522033 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0052075 |
| DUSP7 | dual specificity phosphatase 7 | -0.00520749 |
| KRT18 | keratin 18, type I | -0.00520624 |
| CALCRL | calcitonin receptor-like | -0.00520544 |
| GGT1 | gamma-glutamyltransferase 1 | -0.00520449 |
| ANXA5 | annexin A5 | -0.00519385 |
| CADM1 | cell adhesion molecule 1 | -0.00519238 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00518667 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -0.00518459 |
| SFN | stratifin | -0.00518132 |
| TNNC1 | troponin C type 1 (slow) | -0.00517626 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00515124 |
| MT1G | metallothionein 1G | -0.00512627 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00509165 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.00509041 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00508508 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00508295 |
| COLEC12 | collectin sub-family member 12 | -0.00506223 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.00506169 |
| OGN | osteoglycin | -0.00502503 |
| MT1F | metallothionein 1F | -0.0050002 |
| DACH1 | dachshund family transcription factor 1 | -0.00499261 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00498416 |
| CKM | creatine kinase, muscle | -0.00498232 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.00498188 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00497834 |
| MT1M | metallothionein 1M | -0.00496649 |
| AOX1 | aldehyde oxidase 1 | -0.00495856 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00495319 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00495145 |
| OBSL1 | obscurin-like 1 | -0.00494917 |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa | -0.0049487 |
| ZNF512B | zinc finger protein 512B | -0.0049391 |
| SPART | spartin | -0.00493716 |
| CDC25B | cell division cycle 25B | -0.00493686 |
| ANXA2 | annexin A2 | -0.00492072 |
| ACAA2 | acetyl-CoA acyltransferase 2 | -0.00491233 |
| PDZD2 | PDZ domain containing 2 | -0.00491051 |
| LAMA5 | laminin, alpha 5 | -0.00491036 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00489139 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00486331 |
| MYBPC1 | myosin binding protein C, slow type | -0.00482174 |
| MARCKSL1 | MARCKS-like 1 | -0.00480973 |
| CD320 | CD320 molecule | -0.00479157 |
| KRT8 | keratin 8, type II | -0.00478403 |
| PRKCI | protein kinase C, iota | -0.00478157 |
| NTS | neurotensin | -0.0047813 |
| GOLGA8A | golgin A8 family, member A | -0.00477772 |
| ABHD6 | abhydrolase domain containing 6 | -0.00477558 |
| LAT2 | linker for activation of T cells family, member 2 | -0.00477098 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | -0.00474995 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | -0.00474555 |
| IL32 | interleukin 32 | -0.00474267 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00472592 |
| KRT6A | keratin 6A, type II | -0.00472443 |
| PXDN | peroxidasin | -0.00472414 |
| ARMT1 | acidic residue methyltransferase 1 | -0.00472116 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00469889 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.0046958 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00468706 |
| S100A10 | S100 calcium binding protein A10 | -0.00468628 |
| PLIN2 | perilipin 2 | -0.00468426 |
| GSPT2 | G1 to S phase transition 2 | -0.00468046 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | -0.00467916 |
| ALB | albumin | -0.00466584 |
| WIF1 | WNT inhibitory factor 1 | -0.0046584 |
| CERS4 | ceramide synthase 4 | -0.00464784 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.00462622 |
| SYNPO | synaptopodin | -0.00461305 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00460904 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00460192 |
| PLXNB2 | plexin B2 | -0.00459644 |
| TMEM204 | transmembrane protein 204 | -0.00458935 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00457605 |
| TEK | TEK tyrosine kinase, endothelial | -0.00457211 |
| TRIM16 | tripartite motif containing 16 | -0.00455477 |
| UPP1 | uridine phosphorylase 1 | -0.00454402 |
| C9ORF3 | chromosome 9 open reading frame 3 | -0.00454306 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00453057 |
| DSG3 | desmoglein 3 | -0.00452481 |
| VEGFC | vascular endothelial growth factor C | -0.0045178 |
| GNAS | GNAS complex locus | -0.0045024 |
| MAGED2 | melanoma antigen family D2 | -0.00449658 |
| FLNB | filamin B, beta | -0.00449475 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00448766 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | -0.00447561 |
| SMPX | small muscle protein, X-linked | -0.00446636 |
| ACADL | acyl-CoA dehydrogenase, long chain | -0.0044561 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | -0.00444825 |
| KRT16 | keratin 16, type I | -0.00444632 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | -0.00444501 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00443802 |
| THBS1 | thrombospondin 1 | -0.00443469 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.004432 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | -0.00442367 |
| CD93 | CD93 molecule | -0.00441322 |
| TSPO | translocator protein (18kDa) | -0.00440858 |
| NOX4 | NADPH oxidase 4 | -0.00440319 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | -0.00439652 |
| C7 | complement component 7 | -0.00439218 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.00438934 |
| DUSP5 | dual specificity phosphatase 5 | -0.00437612 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | -0.0043654 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00436437 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.00435767 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00435428 |
| IRF9 | interferon regulatory factor 9 | -0.00434564 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.00433301 |
| PENK | proenkephalin | -0.00432991 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00432811 |
| IGF1R | insulin-like growth factor 1 receptor | -0.00432772 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00432302 |
| KRT5 | keratin 5, type II | -0.00429073 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00428445 |
| TPM2 | tropomyosin 2 (beta) | -0.00428419 |
| MT1H | metallothionein 1H | -0.00428337 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00428121 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00428024 |
