SMARCA4 Gene Set

Dataset ENCODE Transcription Factor Targets
Category genomics
Type transcription factor
Description SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4|The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012] (NCBI Entrez Gene Database, 6597)
External Link http://www.ncbi.nlm.nih.gov/gene/6597
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Genes

57 target genes of the SMARCA4 transcription factor in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.

Symbol Name
ACTR3C ARP3 actin-related protein 3 homolog C (yeast)
ADGRF3 adhesion G protein-coupled receptor F3
ADTRP androgen-dependent TFPI-regulating protein
AMACR alpha-methylacyl-CoA racemase
ANXA2R annexin A2 receptor
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BHLHE40 basic helix-loop-helix family, member e40
BLVRB biliverdin reductase B
C22ORF29 chromosome 22 open reading frame 29
CAT catalase
CD59 CD59 molecule, complement regulatory protein
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
DUSP1 dual specificity phosphatase 1
EPS15 epidermal growth factor receptor pathway substrate 15
EPT1 ethanolaminephosphotransferase 1
FAM83A family with sequence similarity 83, member A
FKBPL FK506 binding protein like
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GP1BB glycoprotein Ib (platelet), beta polypeptide
HDAC6 histone deacetylase 6
HMGB1 high mobility group box 1
KLF1 Kruppel-like factor 1 (erythroid)
KMT2E lysine (K)-specific methyltransferase 2E
LOC153684 uncharacterized LOC153684
LOC648691
LOC648987 uncharacterized LOC648987
LRRC61 leucine rich repeat containing 61
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAD2L1BP MAD2L1 binding protein
MDC1 mediator of DNA-damage checkpoint 1
MIR130B microRNA 130b
MIR196A1 microRNA 196a-1
MIR301B microRNA 301b
MIR4276 microRNA 4276
MIR4766 microRNA 4766
MIR648 microRNA 648
MOB1B MOB kinase activator 1B
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
OSMR oncostatin M receptor
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
POU6F1 POU class 6 homeobox 1
PPBPP2 pro-platelet basic protein pseudogene 2
PPOX protoporphyrinogen oxidase
PRAME preferentially expressed antigen in melanoma
SDE2 SDE2 telomere maintenance homolog (S. pombe)
SDF2L1 stromal cell-derived factor 2-like 1
SLC18B1 solute carrier family 18, subfamily B, member 1
SQRDL sulfide quinone reductase-like (yeast)
TEPP testis, prostate and placenta expressed
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFR2 transferrin receptor 2
THAP7 THAP domain containing 7
THAP7-AS1 THAP7 antisense RNA 1
TUBB1 tubulin, beta 1 class VI
UBE2L3 ubiquitin-conjugating enzyme E2L 3
ZNF280A zinc finger protein 280A