SMARCC2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2|The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6601)
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Genes

279 genes differentially expressed following the SMARCC2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
IRX5 iroquois homeobox 5 2.66486
PLCH2 phospholipase C, eta 2 2.66486
CEP295NL CEP295 N-terminal like 2.66486
GDNF glial cell derived neurotrophic factor 2.66486
GYPB glycophorin B (MNS blood group) 2.66486
PLXNB3 plexin B3 2.66486
TAL2 T-cell acute lymphocytic leukemia 2 2.66486
UBE2U ubiquitin-conjugating enzyme E2U (putative) 2.66486
C3ORF22 chromosome 3 open reading frame 22 2.66486
PAX5 paired box 5 2.66486
DSG3 desmoglein 3 2.66486
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 2.66486
NPAP1 nuclear pore associated protein 1 2.66486
IZUMO3 IZUMO family member 3 2.66486
ZFP57 ZFP57 zinc finger protein 2.66486
PRSS41 protease, serine, 41 2.66486
ECEL1 endothelin converting enzyme-like 1 2.66486
SGPP2 sphingosine-1-phosphate phosphatase 2 2.66486
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 2.66486
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.66486
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.66486
NPIPA8 nuclear pore complex interacting protein family, member A8 2.66486
MUC20 mucin 20, cell surface associated 2.66486
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.66486
TSHZ1 teashirt zinc finger homeobox 1 2.66486
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 2.66486
PRDM1 PR domain containing 1, with ZNF domain 2.66486
FGF9 fibroblast growth factor 9 2.66486
WFDC11 WAP four-disulfide core domain 11 2.66486
TMEM121 transmembrane protein 121 2.66486
S100A1 S100 calcium binding protein A1 2.66486
USP50 ubiquitin specific peptidase 50 2.66486
OR1L6 olfactory receptor, family 1, subfamily L, member 6 2.66486
TMEM71 transmembrane protein 71 2.66486
RGPD3 RANBP2-like and GRIP domain containing 3 2.66486
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 2.66486
NEUROG3 neurogenin 3 2.66486
ZBTB38 zinc finger and BTB domain containing 38 2.66486
C8ORF74 chromosome 8 open reading frame 74 2.66486
SLC22A14 solute carrier family 22, member 14 2.66486
ZNF99 zinc finger protein 99 2.66486
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 2.66486
FAM237B family with sequence similarity 237 member B 2.66486
CERT1 ceramide transporter 1 2.66486
RAG2 recombination activating gene 2 2.66486
YPEL1 yippee-like 1 (Drosophila) 2.66486
VN1R1 vomeronasal 1 receptor 1 2.66486
ELOVL3 ELOVL fatty acid elongase 3 2.66486
STMN4 stathmin-like 4 2.66486
SAXO3 stabilizer of axonemal microtubules 3 2.66486
TMEM271 transmembrane protein 271 2.66486
RTL5 retrotransposon Gag like 5 2.66486
OR9H1 olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene) 2.66486
SPATA31G1 SPATA31 subfamily G member 1 2.66486
THSD8 thrombospondin type 1 domain containing 8 2.66486
LOC124903233 uncharacterized LOC124903233 2.66486
MUCL3 mucin like 3 2.66486
CFAP107 cilia and flagella associated protein 107 2.66486
TENT5D terminal nucleotidyltransferase 5D 2.66486
WDR97 WD repeat domain 97 2.66486
SPATA31C2 SPATA31 subfamily C, member 2 2.66486
FMO2 flavin containing monooxygenase 2 (non-functional) 2.66486
CREB3L3 cAMP responsive element binding protein 3-like 3 2.66486
PRRT1 proline-rich transmembrane protein 1 2.66486
KLRF1 killer cell lectin-like receptor subfamily F, member 1 2.66486
TLR7 toll-like receptor 7 2.66486
SCRT1 scratch family zinc finger 1 2.66486
CBLN3 cerebellin 3 precursor 2.66486
VSX2 visual system homeobox 2 2.66486
IRF4 interferon regulatory factor 4 2.66486
PRR11 proline rich 11 2.66486
PRR4 proline rich 4 (lacrimal) 2.66486
DOK7 docking protein 7 2.66486
SELL selectin L 2.66486
FAM228A family with sequence similarity 228, member A 2.66486
HNF1B HNF1 homeobox B 2.66486
PXDC1 PX domain containing 1 2.66486
STARD6 StAR-related lipid transfer (START) domain containing 6 2.66486
S100G S100 calcium binding protein G 2.66486
GJD2 gap junction protein, delta 2, 36kDa 2.66486
LRTM3 leucine rich repeat transmembrane protein 3 2.66486
NLRP1 NLR family, pyrin domain containing 1 2.66486
SPATA32 spermatogenesis associated 32 2.66486
OR56A1 olfactory receptor, family 56, subfamily A, member 1 2.66486
OR56A4 olfactory receptor, family 56, subfamily A, member 4 2.66486
POF1B premature ovarian failure, 1B 2.66486
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.66486
THTPA thiamine triphosphatase 2.66486
CXCR5 chemokine (C-X-C motif) receptor 5 2.66486
CYSLTR1 cysteinyl leukotriene receptor 1 2.66486
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 2.66486
RSAD2 radical S-adenosyl methionine domain containing 2 2.66486
NACA2 nascent polypeptide-associated complex alpha subunit 2 2.66486
PCDHGB5 protocadherin gamma subfamily B, 5 2.66486
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 2.66486
CMTM2 CKLF-like MARVEL transmembrane domain containing 2 2.66486
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2.66486
TBPL2 TATA box binding protein like 2 2.66486
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1 2.66486
NGB neuroglobin 2.66486
MBOAT4 membrane bound O-acyltransferase domain containing 4 2.66486
FBXO39 F-box protein 39 2.66486
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 2.66486
POU2AF1 POU class 2 associating factor 1 2.66486
PCDHGA4 protocadherin gamma subfamily A, 4 2.66486
RGS8 regulator of G-protein signaling 8 2.66486
CALY calcyon neuron-specific vesicular protein 2.66486
POU4F1 POU class 4 homeobox 1 2.66486
ADAM18 ADAM metallopeptidase domain 18 2.66486
PPP1R27 protein phosphatase 1, regulatory subunit 27 2.66486
SFTA2 surfactant associated 2 2.66486
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 2.66486
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.66486
NT5C1B 5'-nucleotidase, cytosolic IB 2.66486
NT5C1A 5'-nucleotidase, cytosolic IA 2.66486
NT5DC4 5'-nucleotidase domain containing 4 2.66486
LMOD2 leiomodin 2 (cardiac) 2.66486
HOPX HOP homeobox 2.66486
LRRK2 leucine-rich repeat kinase 2 2.66486
FBXO47 F-box protein 47 2.66486
PRPH peripherin 2.66486
LRRC15 leucine rich repeat containing 15 2.66486
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 2.66486
TF transferrin 2.66486
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 2.66486
TOPAZ1 testis and ovary specific PAZ domain containing 1 2.66486
SUN3 Sad1 and UNC84 domain containing 3 2.66486
EPX eosinophil peroxidase 2.66486
AMER2 APC membrane recruitment protein 2 2.66486
LAMP3 lysosomal-associated membrane protein 3 2.66486
TMEM86B transmembrane protein 86B 2.66486
WFDC10A WAP four-disulfide core domain 10A 2.66486
CHRM4 cholinergic receptor, muscarinic 4 2.66486
POTEI POTE ankyrin domain family, member I 2.66486
GH2 growth hormone 2 2.66486
VTCN1 V-set domain containing T cell activation inhibitor 1 2.66486
PRAP1 proline-rich acidic protein 1 2.66486
RTN4RL1 reticulon 4 receptor-like 1 2.66486
MSLN mesothelin 2.66486
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 2.66486
SPRN shadow of prion protein homolog (zebrafish) 2.66486
ADAM20 ADAM metallopeptidase domain 20 2.66486
TEX38 testis expressed 38 2.66486
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) 2.66486
A1CF APOBEC1 complementation factor 2.66486
TMEM156 transmembrane protein 156 2.66486
RNF148 ring finger protein 148 2.66486
DMBT1 deleted in malignant brain tumors 1 2.66486
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 2.66486
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 2.62494
CUBN cubilin (intrinsic factor-cobalamin receptor) 2.62494
LECT2 leukocyte cell-derived chemotaxin 2 2.62494
SGCZ sarcoglycan, zeta 2.62494
CCDC152 coiled-coil domain containing 152 2.62494
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 2.62494
CORO2B coronin, actin binding protein, 2B 2.61142
TBC1D15 TBC1 domain family, member 15 2.5352
FZD7 frizzled class receptor 7 2.48527
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 2.44931
ATP10B ATPase, class V, type 10B 2.44931
ERICH6 glutamate-rich 6 2.44931
GFUS GDP-L-fucose synthase 2.42833
TECTA tectorin alpha 2.41642
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 2.37432
CFAP157 cilia and flagella associated protein 157 2.35311
KRT86 keratin 86, type II 2.34029
C11ORF86 chromosome 11 open reading frame 86 2.33783
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 2.33783
UNC13C unc-13 homolog C (C. elegans) 2.33783
LRRC56 leucine rich repeat containing 56 2.33783
SPX spexin hormone 2.32716
LRRC63 leucine rich repeat containing 63 2.32716
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 2.30533
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 2.28702
C20ORF204 chromosome 20 open reading frame 204 2.23535
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 2.23535
TIMM23B translocase of inner mitochondrial membrane 23 homolog B (yeast) 2.20358
RCCD1 RCC1 domain containing 1 2.19915
ZNF615 zinc finger protein 615 2.19202
CDKL5 cyclin-dependent kinase-like 5 2.1909
AFF2 AF4/FMR2 family, member 2 2.15783
MEAK7 MTOR associated protein, eak-7 homolog 2.15185
ADGRB2 adhesion G protein-coupled receptor B2 2.14715
PPP1R21 protein phosphatase 1, regulatory subunit 21 2.14705
ASTN1 astrotactin 1 2.0917
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 2.08631
ZSCAN21 zinc finger and SCAN domain containing 21 2.08631
GNG4 guanine nucleotide binding protein (G protein), gamma 4 2.06616
TBX19 T-box 19 2.06616
ZNF563 zinc finger protein 563 2.06225
GPR160 G protein-coupled receptor 160 2.05442
FABP7 fatty acid binding protein 7, brain 2.04596
NCOR2 nuclear receptor corepressor 2 2.04278
CHL1 cell adhesion molecule L1-like 2.02125
TMEM62 transmembrane protein 62 2.01306

decreased expression

Symbol Name Standardized Value
KASH5 KASH domain containing 5 -2.66486
TIGD6 tigger transposable element derived 6 -2.66486
EIF5 eukaryotic translation initiation factor 5 -2.66486
MCC mutated in colorectal cancers -2.66486
MMP28 matrix metallopeptidase 28 -2.66486
SMAD9 SMAD family member 9 -2.66486
TFG TRK-fused gene -2.66486
ZNF536 zinc finger protein 536 -2.66486
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D -2.66486
SLC26A7 solute carrier family 26 (anion exchanger), member 7 -2.66486
COX5B cytochrome c oxidase subunit Vb -2.66486
AP5M1 adaptor-related protein complex 5, mu 1 subunit -2.66486
GPR35 G protein-coupled receptor 35 -2.62494
MYL7 myosin, light chain 7, regulatory -2.62494
NXPE1 neurexophilin and PC-esterase domain family, member 1 -2.62494
FAM181B family with sequence similarity 181, member B -2.62494
PCDHGA9 protocadherin gamma subfamily A, 9 -2.62494
BTBD19 BTB (POZ) domain containing 19 -2.62494
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) -2.62494
RHCG Rh family, C glycoprotein -2.62494
NPIPA7 nuclear pore complex interacting protein family, member A7 -2.62494
GPR37L1 G protein-coupled receptor 37 like 1 -2.62494
OR52A1 olfactory receptor, family 52, subfamily A, member 1 -2.62494
TRIM73 tripartite motif containing 73 -2.62494
GPR87 G protein-coupled receptor 87 -2.62494
GFRA3 GDNF family receptor alpha 3 -2.62494
CD48 CD48 molecule -2.62494
EIF4A1 eukaryotic translation initiation factor 4A1 -2.62494
TMIE transmembrane inner ear -2.62494
ZNF774 zinc finger protein 774 -2.62494
OPRK1 opioid receptor, kappa 1 -2.62494
RGSL1 regulator of G-protein signaling like 1 -2.62494
ADAM2 ADAM metallopeptidase domain 2 -2.62494
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 -2.62494
C17ORF114 chromosome 17 open reading frame 114 -2.62494
CFAP126 cilia and flagella associated protein 126 -2.62494
CCDC27 coiled-coil domain containing 27 -2.62494
INSL6 insulin-like 6 -2.62494
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) -2.62494
ERICH6B glutamate-rich 6B -2.62494
MEIS2 Meis homeobox 2 -2.62494
NRSN1 neurensin 1 -2.61833
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 -2.61833
RASL11A RAS-like, family 11, member A -2.58748
SACK1A scaffolding CK1 anchoring protein A -2.58748
KCNIP2 Kv channel interacting protein 2 -2.58748
RPL36A ribosomal protein L36a -2.5484
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 -2.49723
VAMP5 vesicle-associated membrane protein 5 -2.47529
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 -2.45178
RPL27 ribosomal protein L27 -2.42833
FAM111A family with sequence similarity 111, member A -2.41972
CHST10 carbohydrate sulfotransferase 10 -2.41642
PEG10 paternally expressed 10 -2.36774
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -2.36774
CLTB clathrin, light chain B -2.34029
MBTPS2 membrane-bound transcription factor peptidase, site 2 -2.24185
GTF2B general transcription factor IIB -2.22571
LDHA lactate dehydrogenase A -2.22508
ESRP1 epithelial splicing regulatory protein 1 -2.22257
DENND4B DENN/MADD domain containing 4B -2.22043
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 -2.22043
CDC20 cell division cycle 20 -2.21016
NEURL2 neuralized E3 ubiquitin protein ligase 2 -2.19202
TP73 tumor protein p73 -2.17983
BTBD18 BTB (POZ) domain containing 18 -2.17983
TCF24 transcription factor 24 -2.17983
LRRC39 leucine rich repeat containing 39 -2.15185
ZNF878 zinc finger protein 878 -2.15185
CLTA clathrin, light chain A -2.14698
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -2.12561
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -2.11518
SLIRP SRA stem-loop interacting RNA binding protein -2.0833
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.0833
HTATSF1 HIV-1 Tat specific factor 1 -2.08184
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -2.06501
TRPV2 transient receptor potential cation channel, subfamily V, member 2 -2.06501
NLRC5 NLR family, CARD domain containing 5 -2.05866
LRRC41 leucine rich repeat containing 41 -2.05442
MRPL41 mitochondrial ribosomal protein L41 -2.0434
LIPT2 lipoyl(octanoyl) transferase 2 (putative) -2.02714
ANPEP alanyl (membrane) aminopeptidase -2.02714
ZNF320 zinc finger protein 320 -2.02125
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -2.00883