SMG1 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description SMG1 phosphatidylinositol 3-kinase-related kinase|This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternatively spliced transcript variants have been described, but their full-length nature has yet to be determined. [provided by RefSeq, Mar 2013] (NCBI Entrez Gene Database, 23049)
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2 substrates of the kinase SMG1 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
TP53 tumor protein p53
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)