SMO Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description smoothened, frizzled class receptor|The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010] (NCBI Entrez Gene Database, 6608)
External Link http://www.ncbi.nlm.nih.gov/gene/6608
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Genes

84 interacting proteins for SMO from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ADRBK1 adrenergic, beta, receptor kinase 1
ADRBK2 adrenergic, beta, receptor kinase 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARHGAP35 Rho GTPase activating protein 35
ARID1A AT rich interactive domain 1A (SWI-like)
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATF7 activating transcription factor 7
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL6 B-cell CLL/lymphoma 6
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CSMD1 CUB and Sushi multiple domains 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHH desert hedgehog
DNAH9 dynein, axonemal, heavy chain 9
DROSHA drosha, ribonuclease type III
E2F3 E2F transcription factor 3
EBF1 early B-cell factor 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
ELF1 E74-like factor 1 (ets domain transcription factor)
EPHB6 EPH receptor B6
ERCC5 excision repair cross-complementation group 5
GLI1 GLI family zinc finger 1
GLI3 GLI family zinc finger 3
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNG2 guanine nucleotide binding protein (G protein), gamma 2
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC9 histone deacetylase 9
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HNF1A HNF1 homeobox A
HSF4 heat shock transcription factor 4
IDI2 isopentenyl-diphosphate delta isomerase 2
IHH indian hedgehog
ILK integrin-linked kinase
KDM2A lysine (K)-specific demethylase 2A
KIF13B kinesin family member 13B
KMT2B lysine (K)-specific methyltransferase 2B
LPAR2 lysophosphatidic acid receptor 2
LPAR4 lysophosphatidic acid receptor 4
LSM1 LSM1, U6 small nuclear RNA associated
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MED23 mediator complex subunit 23
MTMR6 myotubularin related protein 6
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOR2 nuclear receptor corepressor 2
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NKRF NFKB repressing factor
OLA1 Obg-like ATPase 1
OSBPL1A oxysterol binding protein-like 1A
PANX3 pannexin 3
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDH9 protocadherin 9
POU2F3 POU class 2 homeobox 3
PPAP2B phosphatidic acid phosphatase type 2B
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PTCH1 patched 1
PTCH2 patched 2
SAE1 SUMO1 activating enzyme subunit 1
SENP7 SUMO1/sentrin specific peptidase 7
SHH sonic hedgehog
SIN3A SIN3 transcription regulator family member A
SPEN spen family transcriptional repressor
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SUFU suppressor of fused homolog (Drosophila)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRAF3IP3 TRAF3 interacting protein 3
TRIB3 tribbles pseudokinase 3
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)
WDR35 WD repeat domain 35
WNK4 WNK lysine deficient protein kinase 4
WNT16 wingless-type MMTV integration site family, member 16
YY1 YY1 transcription factor
ZMYND8 zinc finger, MYND-type containing 8
ZNF443 zinc finger protein 443