| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | spermine synthase|This gene encodes a protein belonging to the spermidine/spermin synthase family. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene are associated with X-linked Snyder-Robinson mental retardation syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012] (NCBI Entrez Gene Database, 6611) |
| External Link | https://ncbi.nlm.nih.gov/gene/6611 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the SMS gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHP1 | calcineurin-like EF-hand protein 1 | 0.0330624 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0249275 |
| RB1 | retinoblastoma 1 | 0.0243553 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0199904 |
| NVL | nuclear VCP-like | 0.0173114 |
| KLK10 | kallikrein-related peptidase 10 | 0.0169138 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0166168 |
| LCN2 | lipocalin 2 | 0.0164467 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0160747 |
| MAL | mal, T-cell differentiation protein | 0.015787 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0154371 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0154107 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.0153468 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.015279 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.015222 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0151606 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0151494 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.014995 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0149417 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.0147389 |
| AVPI1 | arginine vasopressin-induced 1 | 0.0146652 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0143215 |
| POPDC3 | popeye domain containing 3 | 0.0141706 |
| HIST1H2BD | histone cluster 1, H2bd | 0.013996 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0137382 |
| MX1 | MX dynamin-like GTPase 1 | 0.0137325 |
| PRPF4 | pre-mRNA processing factor 4 | 0.0129818 |
| ECM1 | extracellular matrix protein 1 | 0.0129424 |
| ARG1 | arginase 1 | 0.0129253 |
| IL6ST | interleukin 6 signal transducer | 0.0129207 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0128344 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0125928 |
| DEFB1 | defensin, beta 1 | 0.0125655 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.0125583 |
| XIC | X chromosome inactivation center | 0.0124885 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0124814 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0124771 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.012469 |
| S100P | S100 calcium binding protein P | 0.0124186 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.0123455 |
| PLK2 | polo-like kinase 2 | 0.0122795 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.012244 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.0120067 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0120029 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.011935 |
| HAL | histidine ammonia-lyase | 0.0118062 |
| CLTB | clathrin, light chain B | 0.0117333 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0117071 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0116792 |
| FST | follistatin | 0.0115977 |
| MYO1B | myosin IB | 0.0114572 |
| TRIM16 | tripartite motif containing 16 | 0.0114251 |
| JUP | junction plakoglobin | 0.0112725 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.0110781 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0110615 |
| EMP2 | epithelial membrane protein 2 | 0.0109178 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0109036 |
| HIST1H2AC | histone cluster 1, H2ac | 0.0108878 |
| LBH | limb bud and heart development | 0.010805 |
| JUNB | jun B proto-oncogene | 0.0107727 |
| BLNK | B-cell linker | 0.0107113 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0107095 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.0107067 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.0106793 |
| EFNA1 | ephrin-A1 | 0.0106088 |
| PTGES | prostaglandin E synthase | 0.0105756 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0105499 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0105494 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.0103622 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0102379 |
| SCEL | sciellin | 0.0102283 |
| CA2 | carbonic anhydrase II | 0.0102224 |
| FAS | Fas cell surface death receptor | 0.0101867 |
| SIK1 | salt-inducible kinase 1 | 0.0101431 |
| TECR | trans-2,3-enoyl-CoA reductase | 0.0101353 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.010106 |
| DNTT | DNA nucleotidylexotransferase | 0.0100531 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.0099423 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00992241 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00989053 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00977647 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00972724 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00970538 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00960012 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.00953375 |
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble | 0.00952175 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.00951512 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00947401 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00945727 |
| CAV2 | caveolin 2 | 0.00944727 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00944235 |
| LAMB1 | laminin, beta 1 | 0.00943618 |
| HMOX1 | heme oxygenase 1 | 0.00943521 |
| SCAND1 | SCAN domain containing 1 | 0.00940192 |
| H1-0 | H1.0 linker histone | 0.00936096 |
| SP110 | SP110 nuclear body protein | 0.00931852 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0092801 |
| MICB | MHC class I polypeptide-related sequence B | 0.00922219 |
| KRT14 | keratin 14, type I | 0.00921992 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00921778 |
| RNF167 | ring finger protein 167 | 0.0092122 |
| MEF2C | myocyte enhancer factor 2C | 0.00918347 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.0091446 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00913648 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.0091168 |
| PPL | periplakin | 0.00906745 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.00894791 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00894498 |
| BPI | bactericidal/permeability-increasing protein | 0.00889559 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00888974 |
| GPX3 | glutathione peroxidase 3 | 0.00887035 |
| CH25H | cholesterol 25-hydroxylase | 0.00885349 |
| NUTF2 | nuclear transport factor 2 | 0.00876392 |
| ADI1 | acireductone dioxygenase 1 | 0.00874698 |
| RHOF | ras homolog family member F (in filopodia) | 0.00873397 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00873116 |
| LAMA3 | laminin, alpha 3 | 0.00871164 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00868326 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.00868068 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.00865057 |
| OSER1 | oxidative stress responsive serine-rich 1 | 0.00864978 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.00864416 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00861422 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.00859926 |
| CLGN | calmegin | 0.00858146 |
| CYP2C18 | cytochrome P450, family 2, subfamily C, polypeptide 18 | 0.0085607 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00855886 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00854766 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.0085359 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00853563 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00849407 |
| PRDX6 | peroxiredoxin 6 | 0.00848615 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00845504 |
| EPX | eosinophil peroxidase | 0.00843659 |
| TNNC1 | troponin C type 1 (slow) | 0.00843322 |
| ERI2 | ERI1 exoribonuclease family member 2 | 0.00840629 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00838691 |
| PEG10 | paternally expressed 10 | 0.00834204 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 0.00834201 |
| CCN2 | cellular communication network factor 2 | 0.00833026 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00831546 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 0.00830256 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00829956 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 0.0082882 |
| RHCG | Rh family, C glycoprotein | 0.00827795 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.00827517 |
| MGMT | O-6-methylguanine-DNA methyltransferase | 0.00824461 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 0.00823091 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00820992 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) | 0.00819696 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00818635 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00817349 |
| MT1X | metallothionein 1X | 0.00814734 |
| TMC5 | transmembrane channel-like 5 | 0.00814116 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0081394 |
| ATF4 | activating transcription factor 4 | 0.00812353 |
| CALML3 | calmodulin-like 3 | 0.00808939 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.00808028 |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 | 0.00807861 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0080715 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00804744 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00802828 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.00801978 |
| UBAP2 | ubiquitin associated protein 2 | 0.00801208 |
| MED6 | mediator complex subunit 6 | 0.00801164 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0079911 |
| IL1R2 | interleukin 1 receptor, type II | 0.0079837 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00797154 |
| SLC25A46 | solute carrier family 25, member 46 | 0.00790301 |
| MPC1 | mitochondrial pyruvate carrier 1 | 0.00789833 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00789591 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.00788493 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.00786817 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00784658 |
| MALL | mal, T-cell differentiation protein-like | 0.00784575 |
| OSR2 | odd-skipped related transciption factor 2 | 0.00782583 |
| CLDN1 | claudin 1 | 0.00782365 |
| IL2RG | interleukin 2 receptor, gamma | 0.0077715 |
| PPID | peptidylprolyl isomerase D | 0.00777024 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | 0.00776164 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00776058 |
| SORT1 | sortilin 1 | 0.00775833 |
| AMOTL2 | angiomotin like 2 | 0.00775793 |
| AK1 | adenylate kinase 1 | 0.00775256 |
| FRMD4B | FERM domain containing 4B | 0.00774595 |
| KLHL21 | kelch-like family member 21 | 0.00774493 |
| KLK7 | kallikrein-related peptidase 7 | 0.00772837 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | 0.00772151 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00772103 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) | 0.00771708 |
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 | 0.00770183 |
| SVIL | supervillin | 0.00770073 |
| KRT5 | keratin 5, type II | 0.00769557 |
| LCMT1 | leucine carboxyl methyltransferase 1 | 0.00768967 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0076881 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0076858 |
| CD69 | CD69 molecule | 0.00763899 |
| SP140L | SP140 nuclear body protein-like | 0.00760267 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00757814 |
| RETN | resistin | 0.00755798 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00754581 |
| ARL4D | ADP-ribosylation factor-like 4D | 0.00754128 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00753383 |
| IRF7 | interferon regulatory factor 7 | 0.00752728 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 0.00750623 |
| FSCN1 | fascin actin-bundling protein 1 | 0.00749778 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.00748818 |
| CPNE1 | copine I | 0.00744948 |
| ODC1 | ornithine decarboxylase 1 | 0.00741868 |
| NIBAN1 | niban apoptosis regulator 1 | 0.007409 |
| YBX3 | Y box binding protein 3 | 0.00740698 |
| TGM1 | transglutaminase 1 | 0.00739821 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00739516 |
| MT1G | metallothionein 1G | 0.00739084 |
| ZNF394 | zinc finger protein 394 | 0.00738381 |
| RIOK3 | RIO kinase 3 | 0.00738229 |
| RPL36 | ribosomal protein L36 | 0.00737584 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00736053 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.0073596 |
| ICOS | inducible T-cell co-stimulator | 0.00735745 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00734813 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.00734728 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 | 0.0073422 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00734088 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | 0.00732927 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00730515 |
| MALT1 | MALT1 paracaspase | 0.00730274 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) | 0.00727594 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00726546 |
| C9ORF3 | chromosome 9 open reading frame 3 | 0.00726033 |
| SARS1 | seryl-tRNA synthetase 1 | 0.00725521 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0072547 |
| IL18 | interleukin 18 | 0.00724843 |
| SSR4 | signal sequence receptor, delta | 0.00723891 |
| CDA | cytidine deaminase | 0.00723663 |
| ATXN3 | ataxin 3 | 0.0072353 |
| FAM46C | family with sequence similarity 46, member C | 0.00723272 |
| ACP3 | acid phosphatase 3 | 0.00722894 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00722819 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | 0.00722744 |
| SERINC5 | serine incorporator 5 | 0.00718394 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00717377 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.00716969 |
| KLK11 | kallikrein-related peptidase 11 | 0.00716834 |
| VPREB1 | pre-B lymphocyte 1 | 0.0071639 |
| ESD | esterase D | 0.00714987 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00714314 |
| SGCE | sarcoglycan, epsilon | 0.0071423 |
| TUBA4A | tubulin, alpha 4a | 0.00712902 |
| CRCT1 | cysteine-rich C-terminal 1 | 0.00710087 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0283567 |
| POSTN | periostin, osteoblast specific factor | -0.0248451 |
| TLCD3A | TLC domain containing 3A | -0.0228107 |
| PCNA | proliferating cell nuclear antigen | -0.0205719 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0201111 |
| HNMT | histamine N-methyltransferase | -0.017927 |
| MGP | matrix Gla protein | -0.0179071 |
| BEX1 | brain expressed, X-linked 1 | -0.0174031 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.016439 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0163054 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0159924 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0159325 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0157908 |
| TLR4 | toll-like receptor 4 | -0.0157889 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0157694 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0157361 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0157117 |
| TYMS | thymidylate synthetase | -0.0156472 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0148012 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0146715 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.0146408 |
| CTSZ | cathepsin Z | -0.0140019 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.0139026 |
| KRT18 | keratin 18, type I | -0.0137118 |
| TMEM176B | transmembrane protein 176B | -0.0133734 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0133656 |
| HOPX | HOP homeobox | -0.013352 |
| PCP4 | Purkinje cell protein 4 | -0.0133172 |
| IL17RB | interleukin 17 receptor B | -0.0132857 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0132388 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.013235 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.0130858 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0130338 |
| TNC | tenascin C | -0.0130105 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.0128295 |
| CPE | carboxypeptidase E | -0.0127592 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.0127344 |
| FHL1 | four and a half LIM domains 1 | -0.0125338 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0125308 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.0124214 |
| COL3A1 | collagen, type III, alpha 1 | -0.0123891 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0122851 |
| PCLAF | PCNA clamp associated factor | -0.0121515 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.0121243 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0119872 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | -0.0117637 |
| TCTA | T-cell leukemia translocation altered | -0.0116478 |
| ASPH | aspartate beta-hydroxylase | -0.0116352 |
| TNS3 | tensin 3 | -0.0116056 |
| APOD | apolipoprotein D | -0.0115781 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.0115084 |
| PDGFD | platelet derived growth factor D | -0.0115066 |
| NES | nestin | -0.0115055 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.0114898 |
| MTMR11 | myotubularin related protein 11 | -0.0114369 |
| DIXDC1 | DIX domain containing 1 | -0.011391 |
| COLEC12 | collectin sub-family member 12 | -0.011316 |
| XYLT1 | xylosyltransferase I | -0.0111554 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0111468 |
| CD14 | CD14 molecule | -0.0111075 |
| ADCY2 | adenylate cyclase 2 (brain) | -0.0110861 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.0110617 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.0110433 |
| MFAP5 | microfibrillar associated protein 5 | -0.0110348 |
| MELK | maternal embryonic leucine zipper kinase | -0.0110118 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0109953 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.0108934 |
| EFHD2 | EF-hand domain family, member D2 | -0.0108879 |
| TAOK3 | TAO kinase 3 | -0.0108542 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.0107602 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.0107385 |
| SNX10 | sorting nexin 10 | -0.0107089 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0106786 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.010669 |
| ZWINT | ZW10 interacting kinetochore protein | -0.0106395 |
| METTL7A | methyltransferase like 7A | -0.0106384 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -0.0106262 |
| IRF8 | interferon regulatory factor 8 | -0.010606 |
| DMXL2 | Dmx-like 2 | -0.0105673 |
| CPQ | carboxypeptidase Q | -0.0105535 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0105531 |
| CBX5 | chromobox homolog 5 | -0.0105478 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0105322 |
| FABP7 | fatty acid binding protein 7, brain | -0.0105295 |
| KRT7 | keratin 7, type II | -0.0104942 |
| TRIM44 | tripartite motif containing 44 | -0.0104684 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.0104487 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | -0.0104424 |
| CD163 | CD163 molecule | -0.0104109 |
| GAL | galanin/GMAP prepropeptide | -0.0103894 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.0103654 |
| CCR1 | chemokine (C-C motif) receptor 1 | -0.0103483 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.0102764 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.0102741 |
| NPTN | neuroplastin | -0.0102698 |
| OLFM1 | olfactomedin 1 | -0.0102358 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.010231 |
| RRM2 | ribonucleotide reductase M2 | -0.0102259 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.0102037 |
| STON1 | stonin 1 | -0.0101756 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0101653 |
| INSM1 | insulinoma-associated 1 | -0.0101437 |
| QKI | QKI, KH domain containing, RNA binding | -0.0101301 |
| CHGB | chromogranin B | -0.0101013 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -0.0100511 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | -0.0100092 |
| FGL2 | fibrinogen-like 2 | -0.00999084 |
| ANXA5 | annexin A5 | -0.00998401 |
| LXN | latexin | -0.00997279 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | -0.00997169 |
| NAP1L3 | nucleosome assembly protein 1-like 3 | -0.00995267 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00994201 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.00989769 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00988974 |
| PDGFC | platelet derived growth factor C | -0.00987716 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta | -0.00985077 |
| SETD6 | SET domain containing 6 | -0.00983214 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00982953 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00979254 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00968796 |
| PTPRA | protein tyrosine phosphatase, receptor type, A | -0.00967905 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00966339 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.0096618 |
| REG3A | regenerating islet-derived 3 alpha | -0.00963706 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.00961659 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00961545 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00958955 |
| COL1A2 | collagen, type I, alpha 2 | -0.00958891 |
| MEIS1 | Meis homeobox 1 | -0.00958036 |
| H2AZ1 | H2A.Z variant histone 1 | -0.0095561 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00953504 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | -0.00951787 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00950822 |
| PMP22 | peripheral myelin protein 22 | -0.00949082 |
| LYZ | lysozyme | -0.00948253 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00945793 |
| SQLE | squalene epoxidase | -0.00944092 |
| PRDX4 | peroxiredoxin 4 | -0.0094229 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00940012 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00938218 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00936339 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00933643 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00932122 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00930446 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00928282 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.00924991 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00922584 |
| TLE4 | transducin-like enhancer of split 4 | -0.00915942 |
| VIM | vimentin | -0.00914773 |
| TOX3 | TOX high mobility group box family member 3 | -0.00913596 |
| CFD | complement factor D (adipsin) | -0.00910696 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00907675 |
| TCF4 | transcription factor 4 | -0.00901387 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00898349 |
| PLPP3 | phospholipid phosphatase 3 | -0.0089825 |
| SATB2 | SATB homeobox 2 | -0.00897889 |
| CP | ceruloplasmin (ferroxidase) | -0.0089617 |
| TFEC | transcription factor EC | -0.00893757 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.00892422 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00891639 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.00890381 |
| NLGN1 | neuroligin 1 | -0.00890122 |
| HDHD5 | haloacid dehalogenase like hydrolase domain containing 5 | -0.0088995 |
| EMC2 | ER membrane protein complex subunit 2 | -0.00878736 |
| RAP1GAP | RAP1 GTPase activating protein | -0.00878347 |
| AMPH | amphiphysin | -0.00877459 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00875895 |
| ASRGL1 | asparaginase like 1 | -0.00875163 |
| CLIP3 | CAP-GLY domain containing linker protein 3 | -0.00870348 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00869272 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00865202 |
| DUT | deoxyuridine triphosphatase | -0.00864717 |
| ITGAV | integrin, alpha V | -0.00862284 |
| PLBD1 | phospholipase B domain containing 1 | -0.00860369 |
| PHKA2 | phosphorylase kinase, alpha 2 (liver) | -0.00859421 |
| LOXL1 | lysyl oxidase-like 1 | -0.00858338 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.00857155 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 | -0.00854849 |
| PAX6 | paired box 6 | -0.00854345 |
| PEG3 | paternally expressed 3 | -0.0085165 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00851073 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00849071 |
| ANK2 | ankyrin 2, neuronal | -0.00846847 |
| CHRDL1 | chordin-like 1 | -0.00845998 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00844681 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00843829 |
| LMNB1 | lamin B1 | -0.00842784 |
| GATA2 | GATA binding protein 2 | -0.00841593 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | -0.00841481 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00840783 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.00837263 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00834371 |
| MB | myoglobin | -0.00834368 |
| SNX5 | sorting nexin 5 | -0.00832259 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00831166 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | -0.0083062 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.00829988 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00828987 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.00826908 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | -0.00819622 |
| FBXO21 | F-box protein 21 | -0.00818769 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00817676 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.00816761 |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) | -0.00815991 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00815482 |
| FRY | furry homolog (Drosophila) | -0.00810266 |
| GOLGA8H | golgin A8 family, member H | -0.008082 |
| TRIM9 | tripartite motif containing 9 | -0.0080613 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00805572 |
| KRT19 | keratin 19, type I | -0.00805404 |
| MXRA5 | matrix-remodelling associated 5 | -0.0080519 |
| WSB2 | WD repeat and SOCS box containing 2 | -0.00804904 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa | -0.00804535 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00803418 |
| ELN | elastin | -0.00799932 |
| MCM6 | minichromosome maintenance complex component 6 | -0.00798481 |
| PLIN1 | perilipin 1 | -0.00797902 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.00796864 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00795028 |
| CBS | cystathionine-beta-synthase | -0.00794431 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.00794248 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00793938 |
| SDC2 | syndecan 2 | -0.0079348 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00793215 |
| RIN2 | Ras and Rab interactor 2 | -0.00791999 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.00791622 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.00791028 |
| TYMP | thymidine phosphorylase | -0.00788972 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | -0.00786714 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.00785519 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | -0.00784012 |
| CBR4 | carbonyl reductase 4 | -0.00782302 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00782224 |
| RGS5 | regulator of G-protein signaling 5 | -0.00780087 |
| SALL2 | spalt-like transcription factor 2 | -0.00778815 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00778639 |
| THYN1 | thymocyte nuclear protein 1 | -0.00777672 |
| ELAPOR1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | -0.00776902 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00776455 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00775678 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00775149 |
| REG1A | regenerating islet-derived 1 alpha | -0.00773808 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.00773446 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.00772768 |
| MCM5 | minichromosome maintenance complex component 5 | -0.00770876 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00769512 |
| MEG3 | maternally expressed 3 (non-protein coding) | -0.00769042 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.00768438 |
| MMP9 | matrix metallopeptidase 9 | -0.00767614 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 | -0.00765627 |
