SMURF1 Gene Set

Dataset Hub Proteins Protein-Protein Interactions
Category physical interactions
Type hub protein
Description SMAD specific E3 ubiquitin protein ligase 1|This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 57154)
External Link http://www.ncbi.nlm.nih.gov/gene/57154
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Genes

119 interacting proteins for hub protein SMURF1 from the curated Hub Proteins Protein-Protein Interactions dataset.

Symbol Name
ACVR1B activin A receptor, type IB
ANAPC5 anaphase promoting complex subunit 5
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGAP15 Rho GTPase activating protein 15
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARL14 ADP-ribosylation factor-like 14
ARL4D ADP-ribosylation factor-like 4D
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
AVEN apoptosis, caspase activation inhibitor
CDC40 cell division cycle 40
CDK14 cyclin-dependent kinase 14
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CSNK2A2 casein kinase 2, alpha prime polypeptide
CUL5 cullin 5
CXXC1 CXXC finger protein 1
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DUSP13 dual specificity phosphatase 13
DVL2 dishevelled segment polarity protein 2
ECSIT ECSIT signalling integrator
ELP3 elongator acetyltransferase complex subunit 3
ETV6 ets variant 6
FBXO24 F-box protein 24
FBXO3 F-box protein 3
FBXO30 F-box protein 30
FCHO1 FCH domain only 1
FKBP1A FK506 binding protein 1A, 12kDa
GAR1 GAR1 ribonucleoprotein
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GRIPAP1 GRIP1 associated protein 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
ING2 inhibitor of growth family, member 2
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRAK2 interleukin-1 receptor-associated kinase 2
LHX9 LIM homeobox 9
LIMS1 LIM and senescent cell antigen-like domains 1
LONRF3 LON peptidase N-terminal domain and ring finger 3
MAP2K3 mitogen-activated protein kinase kinase 3
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K7 mitogen-activated protein kinase kinase kinase 7
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit
NDFIP2 Nedd4 family interacting protein 2
OCLN occludin
OSBPL3 oxysterol binding protein-like 3
OXSR1 oxidative stress responsive 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK1IP1 PAK1 interacting protein 1
PDLIM7 PDZ and LIM domain 7 (enigma)
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PRKCZ protein kinase C, zeta
PWP1 PWP1 homolog (S. cerevisiae)
RAPSN receptor-associated protein of the synapse
RASD2 RASD family, member 2
RGL3 ral guanine nucleotide dissociation stimulator-like 3
RHOA ras homolog family member A
RHOBTB1 Rho-related BTB domain containing 1
RHPN2 rhophilin, Rho GTPase binding protein 2
RIPK2 receptor-interacting serine-threonine kinase 2
RIT1 Ras-like without CAAX 1
RLIM ring finger protein, LIM domain interacting
RNF11 ring finger protein 11
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
RNF14 ring finger protein 14
RNF141 ring finger protein 141
RPS27A ribosomal protein S27a
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RTKN rhotekin
RUNX3 runt-related transcription factor 3
SASH3 SAM and SH3 domain containing 3
SF3A1 splicing factor 3a, subunit 1, 120kDa
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD5 SMAD family member 5
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SQSTM1 sequestosome 1
SRSF4 serine/arginine-rich splicing factor 4
SRSF5 serine/arginine-rich splicing factor 5
STAT1 signal transducer and activator of transcription 1, 91kDa
STK35 serine/threonine kinase 35
STRAP serine/threonine kinase receptor associated protein
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TBL2 transducin (beta)-like 2
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNNT1 troponin T type 1 (skeletal, slow)
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF4 TNF receptor-associated factor 4
TRAF5 TNF receptor-associated factor 5
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIB3 tribbles pseudokinase 3
TRIM25 tripartite motif containing 25
TRIM35 tripartite motif containing 35
TSSK4 testis-specific serine kinase 4
TTC17 tetratricopeptide repeat domain 17
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBTF upstream binding transcription factor, RNA polymerase I
UBXN1 UBX domain protein 1
UHMK1 U2AF homology motif (UHM) kinase 1
ULK4 unc-51 like kinase 4
UNKL unkempt family zinc finger-like
USP45 ubiquitin specific peptidase 45
WDR61 WD repeat domain 61
WEE1 WEE1 G2 checkpoint kinase
XPO1 exportin 1
ZBTB8A zinc finger and BTB domain containing 8A
ZBTB8B zinc finger and BTB domain containing 8B