SNAI2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description snail family zinc finger 2|This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6591)
External Link http://www.ncbi.nlm.nih.gov/gene/6591
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Genes

21 interacting proteins for SNAI2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
APP amyloid beta (A4) precursor protein
CHD4 chromodomain helicase DNA binding protein 4
GSK3B glycogen synthase kinase 3 beta
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HNF4A hepatocyte nuclear factor 4, alpha
KDM1A lysine (K)-specific demethylase 1A
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PPP6R3 protein phosphatase 6, regulatory subunit 3
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TJP2 tight junction protein 2
TP53 tumor protein p53
UBC ubiquitin C