SNAP29 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description synaptosomal-associated protein, 29kDa|This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9342)
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Genes

347 genes differentially expressed following the SNAP29 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
OR2A1 olfactory receptor, family 2, subfamily A, member 1 3.05201
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 3.05201
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 3.05201
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 3.05201
PCDHB4 protocadherin beta 4 3.05201
SOX18 SRY (sex determining region Y)-box 18 3.05201
OSGIN1 oxidative stress induced growth inhibitor 1 3.05201
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like 3.05201
ECEL1 endothelin converting enzyme-like 1 3.05201
PCDHGB3 protocadherin gamma subfamily B, 3 3.05201
CCNB3 cyclin B3 3.05201
TMEM171 transmembrane protein 171 3.05201
ENTHD1 ENTH domain containing 1 3.05201
IZUMO3 IZUMO family member 3 3.05201
NKX3-1 NK3 homeobox 1 3.05201
SLC22A14 solute carrier family 22, member 14 3.05201
P2RY8 purinergic receptor P2Y, G-protein coupled, 8 3.05201
LTC4S leukotriene C4 synthase 3.05201
ZNF582 zinc finger protein 582 3.05201
GJA5 gap junction protein, alpha 5, 40kDa 3.05201
TMPRSS11A transmembrane protease, serine 11A 3.05201
CAMK1 calcium/calmodulin-dependent protein kinase I 3.05201
ZACN zinc activated ligand-gated ion channel 3.05201
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 3.05201
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 3.05201
OSBPL7 oxysterol binding protein-like 7 3.05201
PTH2 parathyroid hormone 2 3.05201
IFI6 interferon, alpha-inducible protein 6 3.05201
S100A9 S100 calcium binding protein A9 3.05201
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative) 3.05201
SLC44A4 solute carrier family 44, member 4 3.05201
AVP arginine vasopressin 3.05201
LGALS9 lectin, galactoside-binding, soluble, 9 3.05201
GALR3 galanin receptor 3 3.05201
RPEL1 ribulose-5-phosphate-3-epimerase-like 1 3.05201
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 3.05201
PRR22 proline rich 22 3.05201
PANO1 proapoptotic nucleolar protein 1 3.05201
SOWAHB sosondowah ankyrin repeat domain family member B 3.05201
CRIP2 cysteine-rich protein 2 3.05201
PLCH2 phospholipase C, eta 2 3.05201
GDNF glial cell derived neurotrophic factor 3.05201
FLI1 Fli-1 proto-oncogene, ETS transcription factor 3.05201
CA1 carbonic anhydrase I 3.05201
CXCL2 chemokine (C-X-C motif) ligand 2 3.05201
C1ORF146 chromosome 1 open reading frame 146 3.05201
C9ORF152 chromosome 9 open reading frame 152 3.05201
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 3.05201
CD68 CD68 molecule 3.05201
CRH corticotropin releasing hormone 3.05201
TTLL2 tubulin tyrosine ligase-like family member 2 3.05201
PCDHGA11 protocadherin gamma subfamily A, 11 3.05201
RS1 retinoschisin 1 3.05201
SPMAP2L sperm microtubule associated protein 2 like 3.05201
SPATS1 spermatogenesis associated, serine-rich 1 3.05201
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 3.05201
CD300LF CD300 molecule-like family member f 3.05201
RIPK4 receptor-interacting serine-threonine kinase 4 3.05201
ALX1 ALX homeobox 1 3.05201
CXCL13 chemokine (C-X-C motif) ligand 13 3.05201
ACTA2 actin, alpha 2, smooth muscle, aorta 3.05201
RHCG Rh family, C glycoprotein 3.05201
FIMP1 fertilization-influencing membrane protein 1 3.05201
FMO2 flavin containing monooxygenase 2 (non-functional) 3.05201
MYZAP myocardial zonula adherens protein 3.05201
H3-5 H3.5 histone 3.05201
ALPG alkaline phosphatase, germ cell 3.05201
SPMIP1 sperm microtubule inner protein 1 3.05201
ZC3H11C zinc finger CCCH-type containing 11C 3.05201
SMIM47 small integral membrane protein 47 3.05201
STRIT1 small transmembrane regulator of ion transport 1 3.05201
LRRC8C-DT LRRC8C divergent transcript 3.05201
C17ORF114 chromosome 17 open reading frame 114 3.05201
LINC02798 long intergenic non-protein coding RNA 2798 3.05201
MINDY4B MINDY family member 4B 3.05201
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 3.05201
MARCHF10 membrane associated ring-CH-type finger 10 3.05201
MINAR1 membrane integral NOTCH2 associated receptor 1 3.05201
SMPX small muscle protein, X-linked 3.05201
RASD1 RAS, dexamethasone-induced 1 3.05201
FLT3LG fms-related tyrosine kinase 3 ligand 3.05201
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 3.05201
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 3.05201
GOLGA6L4 golgin A6 family-like 4 3.05201
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 3.05201
CCR6 chemokine (C-C motif) receptor 6 3.05201
AMBP alpha-1-microglobulin/bikunin precursor 3.05201
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 3.05201
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 3.05201
TUBA3D tubulin, alpha 3d 3.05201
TLE6 transducin-like enhancer of split 6 3.05201
OVOL3 ovo-like zinc finger 3 3.05201
RNF113B ring finger protein 113B 3.05201
ZNF446 zinc finger protein 446 3.05201
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 3.05201
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 3.05201
TBX10 T-box 10 3.05201
GDF6 growth differentiation factor 6 3.05201
PTH parathyroid hormone 3.05201
ALG10B ALG10B, alpha-1,2-glucosyltransferase 3.05201
C7ORF57 chromosome 7 open reading frame 57 3.05201
CCR3 chemokine (C-C motif) receptor 3 3.05201
MYOG myogenin (myogenic factor 4) 3.05201
ZAN zonadhesin (gene/pseudogene) 3.05201
PCDHA4 protocadherin alpha 4 3.05201
MR1 major histocompatibility complex, class I-related 3.05201
KLHL41 kelch-like family member 41 3.05201
WFDC1 WAP four-disulfide core domain 1 3.05201
GOLGA6B golgin A6 family, member B 3.05201
OAZ3 ornithine decarboxylase antizyme 3 3.05201
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 3.05201
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 3.05201
WDR3 WD repeat domain 3 3.05201
DRD5 dopamine receptor D5 3.05201
C17ORF99 chromosome 17 open reading frame 99 3.05201
IL1A interleukin 1, alpha 3.05201
COL17A1 collagen, type XVII, alpha 1 3.05201
ZNF547 zinc finger protein 547 3.05201
PDE2A phosphodiesterase 2A, cGMP-stimulated 3.05201
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 3.05201
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 3.05201
DNAH10 dynein, axonemal, heavy chain 10 3.05201
CLDN34 claudin 34 3.05201
HCRT hypocretin (orexin) neuropeptide precursor 3.05201
TNR tenascin R 3.05201
SLCO2A1 solute carrier organic anion transporter family, member 2A1 3.05201
F2RL2 coagulation factor II (thrombin) receptor-like 2 3.05201
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2 3.05201
ETNPPL ethanolamine-phosphate phospho-lyase 3.05201
HHATL hedgehog acyltransferase-like 3.05201
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 3.05201
FBXO47 F-box protein 47 3.05201
ZNF843 zinc finger protein 843 3.05201
SLC38A8 solute carrier family 38, member 8 3.05201
CLUL1 clusterin-like 1 (retinal) 3.05201
INSL6 insulin-like 6 3.05201
TSPAN19 tetraspanin 19 3.05201
SLC35F6 solute carrier family 35, member F6 3.05201
TMEM253 transmembrane protein 253 3.05201
PLA2G2C phospholipase A2, group IIC 3.05201
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 3.05201
AOC2 amine oxidase, copper containing 2 (retina-specific) 3.05201
HPGDS hematopoietic prostaglandin D synthase 3.05201
C22ORF31 chromosome 22 open reading frame 31 3.05201
PRTN3 proteinase 3 3.05201
TMEM31 transmembrane protein 31 3.05201
RELN reelin 3.05201
MSR1 macrophage scavenger receptor 1 3.05201
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2 3.05201
TG thyroglobulin 3.05201
ZGLP1 zinc finger, GATA-like protein 1 3.05201
VWF von Willebrand factor 3.05201
PYGO1 pygopus family PHD finger 1 3.05201
DLX1 distal-less homeobox 1 3.05201
PRSS38 protease, serine, 38 3.05201
IP6K3 inositol hexakisphosphate kinase 3 3.05201
OTOP2 otopetrin 2 3.05201
OPRK1 opioid receptor, kappa 1 3.05201
SHOX2 short stature homeobox 2 3.05201
BTBD19 BTB (POZ) domain containing 19 3.05201
TMPRSS13 transmembrane protease, serine 13 3.05201
LY6G5C lymphocyte antigen 6 complex, locus G5C 3.05201
SYTL5 synaptotagmin-like 5 3.05201
SLC51B solute carrier family 51, beta subunit 3.05201
APOL6 apolipoprotein L, 6 3.05201
GGN gametogenetin 3.05201
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 3.05201
AMER2 APC membrane recruitment protein 2 3.05201
POU3F2 POU class 3 homeobox 2 3.05201
A1CF APOBEC1 complementation factor 3.05201
ADRA1D adrenoceptor alpha 1D 3.05201
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 3.05201
CLEC2B C-type lectin domain family 2, member B 3.05201
IRX3 iroquois homeobox 3 3.05201
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 3.05201
TMEM88 transmembrane protein 88 3.05201
PPP1R3A protein phosphatase 1, regulatory subunit 3A 3.05201
PPP1R3C protein phosphatase 1, regulatory subunit 3C 3.05201
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 3.05201
ROM1 retinal outer segment membrane protein 1 3.05201
GPER1 G protein-coupled estrogen receptor 1 3.05201
GAB3 GRB2-associated binding protein 3 3.05201
FRS3 fibroblast growth factor receptor substrate 3 3.05201
FCN3 ficolin (collagen/fibrinogen domain containing) 3 3.05201
KPNA7 karyopherin alpha 7 (importin alpha 8) 3.05201
CMTM2 CKLF-like MARVEL transmembrane domain containing 2 3.05201
PLA2G4D phospholipase A2, group IVD (cytosolic) 3.05201
NGFR nerve growth factor receptor 3.05201
HSPB2 heat shock 27kDa protein 2 3.05201
CCDC154 coiled-coil domain containing 154 3.05201
CASS4 Cas scaffolding protein family member 4 3.05201
TMEM132D transmembrane protein 132D 3.05201
CSPG4 chondroitin sulfate proteoglycan 4 3.05201
EFTUD2 elongation factor Tu GTP binding domain containing 2 2.96256
KAT2B K(lysine) acetyltransferase 2B 2.81227
KCTD21 potassium channel tetramerization domain containing 21 2.81227
SLC68A1 solute carrier family 68 member 1 2.72481
CAPN11 calpain 11 2.69048
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 2.69048
ARHGAP9 Rho GTPase activating protein 9 2.69048
TRMT9B tRNA methyltransferase 9B (putative) 2.62373
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 2.54788
LMOD1 leiomodin 1 (smooth muscle) 2.52766
BRAP BRCA1 associated protein 2.51338
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) 2.45869
ZNF287 zinc finger protein 287 2.42543
RBM27 RNA binding motif protein 27 2.41444
NYX nyctalopin 2.39599
OXNAD1 oxidoreductase NAD-binding domain containing 1 2.38832
HNRNPK heterogeneous nuclear ribonucleoprotein K 2.38059
C1ORF216 chromosome 1 open reading frame 216 2.36908
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 2.34953
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 2.34809
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe) 2.3008
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2.30004
TMC1 transmembrane channel-like 1 2.27355
RBM12 RNA binding motif protein 12 2.26184
FAM184B family with sequence similarity 184, member B 2.2461
COMT catechol-O-methyltransferase 2.23977
ERP44 endoplasmic reticulum protein 44 2.22943
GPR179 G protein-coupled receptor 179 2.22254
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 2.16133
CPNE9 copine family member IX 2.14292
TRIM5 tripartite motif containing 5 2.13998
TSC22D1 TSC22 domain family, member 1 2.1273
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) 2.12604
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 2.12217
TCEA1 transcription elongation factor A (SII), 1 2.1214
DOK6 docking protein 6 2.11437
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 2.10939
WTIP Wilms tumor 1 interacting protein 2.10939
SQLE squalene epoxidase 2.09822
RNF180 ring finger protein 180 2.08902
DLAT dihydrolipoamide S-acetyltransferase 2.0718
UNC13B unc-13 homolog B (C. elegans) 2.06252
TGFB1 transforming growth factor, beta 1 2.02165
UBXN4 UBX domain protein 4 2.01713
DELE1 DAP3 binding cell death enhancer 1 2.00327
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 2.00327

decreased expression

Symbol Name Standardized Value
FNDC11 fibronectin type III domain containing 11 -3.05201
SGPP2 sphingosine-1-phosphate phosphatase 2 -3.05201
C6ORF52 chromosome 6 open reading frame 52 -3.05201
C16ORF89 chromosome 16 open reading frame 89 -3.05201
SOX10 SRY (sex determining region Y)-box 10 -3.05201
C2ORF76 chromosome 2 open reading frame 76 -3.05201
ARID5A AT rich interactive domain 5A (MRF1-like) -3.05201
ZNF563 zinc finger protein 563 -3.05201
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) -3.05201
ELL3 elongation factor RNA polymerase II-like 3 -3.05201
CORIN corin, serine peptidase -3.05201
CALD1 caldesmon 1 -3.05201
ZBTB42 zinc finger and BTB domain containing 42 -3.05201
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) -3.05201
ZNF527 zinc finger protein 527 -3.05201
FMO3 flavin containing monooxygenase 3 -3.05201
TMEM190 transmembrane protein 190 -3.05201
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) -3.05201
MLANA melan-A -3.05201
SPMIP2 sperm microtubule inner protein 2 -3.05201
CATSPERD catsper channel auxiliary subunit delta -3.05201
CATSPER4 cation channel, sperm associated 4 -3.05201
PRB2 proline-rich protein BstNI subfamily 2 -3.05201
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -3.05201
CCDC110 coiled-coil domain containing 110 -3.05201
STAB2 stabilin 2 -3.05201
SYNM synemin, intermediate filament protein -3.05201
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) -3.05201
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -3.05201
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled -3.05201
USP18 ubiquitin specific peptidase 18 -3.05201
TDRD12 tudor domain containing 12 -3.05201
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -3.05201
GCOM1 GRINL1A complex locus 1 -3.05201
CRYBB1 crystallin, beta B1 -3.05201
C2CD4C C2 calcium-dependent domain containing 4C -3.05201
CHMP4C charged multivesicular body protein 4C -3.05201
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 -3.05201
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -2.88316
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 -2.75901
GRID1 glutamate receptor, ionotropic, delta 1 -2.75901
SPTAN1 spectrin, alpha, non-erythrocytic 1 -2.69048
INF2 inverted formin, FH2 and WH2 domain containing -2.66596
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 -2.62144
BTBD2 BTB (POZ) domain containing 2 -2.60762
EIF3L eukaryotic translation initiation factor 3, subunit L -2.60762
HGH1 HGH1 homolog (S. cerevisiae) -2.56914
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 -2.55629
TIAM2 T-cell lymphoma invasion and metastasis 2 -2.55273
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B -2.49369
OSBPL3 oxysterol binding protein-like 3 -2.47407
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 -2.44655
TMEM17 transmembrane protein 17 -2.44655
IAPP islet amyloid polypeptide -2.44655
TMEM114 transmembrane protein 114 -2.44655
CNTN3 contactin 3 (plasmacytoma associated) -2.44655
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -2.44655
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) -2.44655
RUSF1 RUS family member 1 -2.44655
AHR aryl hydrocarbon receptor -2.42543
EIF3E eukaryotic translation initiation factor 3, subunit E -2.38832
SFT2D3 SFT2 domain containing 3 -2.37069
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -2.37036
FAM161A family with sequence similarity 161, member A -2.3489
ARL6 ADP-ribosylation factor-like 6 -2.32863
YAF2 YY1 associated factor 2 -2.32333
ZNF70 zinc finger protein 70 -2.32333
WNT5B wingless-type MMTV integration site family, member 5B -2.32333
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 -2.32333
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 -2.32333
BEST1 bestrophin 1 -2.32333
OGFRL1 opioid growth factor receptor-like 1 -2.3147
FABP7 fatty acid binding protein 7, brain -2.30543
TMBIM4 transmembrane BAX inhibitor motif containing 4 -2.30253
TMC4 transmembrane channel-like 4 -2.30087
CUL9 cullin 9 -2.28019
DTD2 D-tyrosyl-tRNA deacylase 2 (putative) -2.25812
SALL1 spalt-like transcription factor 1 -2.25549
TBCA tubulin folding cofactor A -2.24223
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 -2.23824
MCU mitochondrial calcium uniporter -2.23502
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -2.19254
SMIM7 small integral membrane protein 7 -2.16324
TBC1D31 TBC1 domain family, member 31 -2.15024
BROX BRO1 domain and CAAX motif containing -2.1415
SPATA20 spermatogenesis associated 20 -2.1311
CFAP58 cilia and flagella associated protein 58 -2.1311
LY6G5B lymphocyte antigen 6 complex, locus G5B -2.1311
TRPV4 transient receptor potential cation channel, subfamily V, member 4 -2.1311
SELENOT selenoprotein T -2.1267
NUP133 nucleoporin 133kDa -2.12589
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.12545
XBP1 X-box binding protein 1 -2.12545
FAM133B family with sequence similarity 133, member B -2.12498
MYO15B myosin XVB -2.12249
RPSA2 ribosomal protein SA 2 -2.11184
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) -2.10939
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) -2.10939
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -2.10939
TCTN2 tectonic family member 2 -2.10294
MRPL10 mitochondrial ribosomal protein L10 -2.04707
MAP3K10 mitogen-activated protein kinase kinase kinase 10 -2.04547
MFF mitochondrial fission factor -2.03596
DGKE diacylglycerol kinase, epsilon 64kDa -2.03573
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -2.03573
USH1C Usher syndrome 1C (autosomal recessive, severe) -2.02518
XRRA1 X-ray radiation resistance associated 1 -2.02346
PCCA propionyl CoA carboxylase, alpha polypeptide -2.02165