Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
Category | transcriptomics |
Type | gene perturbation |
Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
External Link | http://www.broadinstitute.org/gsea/msigdb/cards/SNF5_DN.V1_UP |
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336 genes differentially expressed following the SNF5_DN.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
Symbol | Name |
---|---|
ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 |
ABHD14A | abhydrolase domain containing 14A |
ABI3BP | ABI family, member 3 (NESH) binding protein |
ACTL6A | actin-like 6A |
ADI1 | acireductone dioxygenase 1 |
AGTR2 | angiotensin II receptor, type 2 |
AIF1 | allograft inflammatory factor 1 |
ANPEP | alanyl (membrane) aminopeptidase |
APOD | apolipoprotein D |
APOE | apolipoprotein E |
AQP5 | aquaporin 5 |
ASS1 | argininosuccinate synthase 1 |
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
AURKB | aurora kinase B |
BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
C14ORF37 | chromosome 14 open reading frame 37 |
C17ORF49 | chromosome 17 open reading frame 49 |
C19ORF48 | chromosome 19 open reading frame 48 |
C1QC | complement component 1, q subcomponent, C chain |
C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
C1R | complement component 1, r subcomponent |
C1S | complement component 1, s subcomponent |
C3AR1 | complement component 3a receptor 1 |
C5ORF28 | chromosome 5 open reading frame 28 |
CCDC132 | coiled-coil domain containing 132 |
CCL3 | chemokine (C-C motif) ligand 3 |
CD109 | CD109 molecule |
CD48 | CD48 molecule |
CD52 | CD52 molecule |
CD53 | CD53 molecule |
CD68 | CD68 molecule |
CD9 | CD9 molecule |
CD93 | CD93 molecule |
CDO1 | cysteine dioxygenase type 1 |
CFP | complement factor properdin |
CKAP2 | cytoskeleton associated protein 2 |
COL15A1 | collagen, type XV, alpha 1 |
COL26A1 | collagen, type XXVI, alpha 1 |
COPS4 | COP9 signalosome subunit 4 |
CORO1C | coronin, actin binding protein, 1C |
CSF1R | colony stimulating factor 1 receptor |
CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
CXCL10 | chemokine (C-X-C motif) ligand 10 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
CXCR4 | chemokine (C-X-C motif) receptor 4 |
DARS | aspartyl-tRNA synthetase |
DCAKD | dephospho-CoA kinase domain containing |
DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DENND4C | DENN/MADD domain containing 4C |
DHRS1 | dehydrogenase/reductase (SDR family) member 1 |
DLK1 | delta-like 1 homolog (Drosophila) |
DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
EGFL6 | EGF-like-domain, multiple 6 |
EGR2 | early growth response 2 |
ELN | elastin |
ENPP3 | ectonucleotide pyrophosphatase/phosphodiesterase 3 |
ERAP1 | endoplasmic reticulum aminopeptidase 1 |
EVI2A | ecotropic viral integration site 2A |
EVL | Enah/Vasp-like |
EWSR1 | EWS RNA-binding protein 1 |
FABP7 | fatty acid binding protein 7, brain |
FAM105A | family with sequence similarity 105, member A |
FAM65B | family with sequence similarity 65, member B |
FBLN1 | fibulin 1 |
FBXO6 | F-box protein 6 |
FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
FDPS | farnesyl diphosphate synthase |
FGF18 | fibroblast growth factor 18 |
FMOD | fibromodulin |
FNBP1 | formin binding protein 1 |
FNDC1 | fibronectin type III domain containing 1 |
FYB | FYN binding protein |
GABRQ | gamma-aminobutyric acid (GABA) A receptor, theta |
GALC | galactosylceramidase |
GAS1 | growth arrest-specific 1 |
GBP1 | guanylate binding protein 1, interferon-inducible |
GOT1 | glutamic-oxaloacetic transaminase 1, soluble |
GRK6 | G protein-coupled receptor kinase 6 |
GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
GTF3A | general transcription factor IIIA |
HAPLN2 | hyaluronan and proteoglycan link protein 2 |
HAT1 | histone acetyltransferase 1 |
IARS | isoleucyl-tRNA synthetase |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
IER5L | immediate early response 5-like |
IFI44L | interferon-induced protein 44-like |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
ISG20 | interferon stimulated exonuclease gene 20kDa |
ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
KCNJ10 | potassium channel, inwardly rectifying subfamily J, member 10 |
KIAA1524 | KIAA1524 |
KIF20A | kinesin family member 20A |
KLHL42 | kelch-like family member 42 |
LAMB2 | laminin, beta 2 (laminin S) |
LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
LHX2 | LIM homeobox 2 |
LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
LIX1 | Lix1 homolog (chicken) |
LMO2 | LIM domain only 2 (rhombotin-like 1) |
LRP5 | low density lipoprotein receptor-related protein 5 |
LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
LY86 | lymphocyte antigen 86 |
MCM5 | minichromosome maintenance complex component 5 |
MEDAG | mesenteric estrogen-dependent adipogenesis |
MEST | mesoderm specific transcript |
MKL1 | megakaryoblastic leukemia (translocation) 1 |
MLF2 | myeloid leukemia factor 2 |
MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
MSX1 | msh homeobox 1 |
MT3 | metallothionein 3 |
MYH1 | myosin, heavy chain 1, skeletal muscle, adult |
MYH2 | myosin, heavy chain 2, skeletal muscle, adult |
NCAN | neurocan |
NCAPG2 | non-SMC condensin II complex, subunit G2 |
NDE1 | nudE neurodevelopment protein 1 |
NRROS | negative regulator of reactive oxygen species |
OASL | 2'-5'-oligoadenylate synthetase-like |
OLIG1 | oligodendrocyte transcription factor 1 |
PENK | proenkephalin |
PIGP | phosphatidylinositol glycan anchor biosynthesis, class P |
PITPNB | phosphatidylinositol transfer protein, beta |
PLCE1 | phospholipase C, epsilon 1 |
PLD3 | phospholipase D family, member 3 |
PLD4 | phospholipase D family, member 4 |
PLEK | pleckstrin |
PNN | pinin, desmosome associated protein |
POFUT2 | protein O-fucosyltransferase 2 |
PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
PPP4C | protein phosphatase 4, catalytic subunit |
PRKCDBP | protein kinase C, delta binding protein |
PRPS1 | phosphoribosyl pyrophosphate synthetase 1 |
PRRX2 | paired related homeobox 2 |
PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 |
PTPRC | protein tyrosine phosphatase, receptor type, C |
RABAC1 | Rab acceptor 1 (prenylated) |
RBL1 | retinoblastoma-like 1 |
RCC1 | regulator of chromosome condensation 1 |
RNF13 | ring finger protein 13 |
SCG2 | secretogranin II |
SELPLG | selectin P ligand |
SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
SFRP2 | secreted frizzled-related protein 2 |
SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
SMAD2 | SMAD family member 2 |
SOSTDC1 | sclerostin domain containing 1 |
SOX2 | SRY (sex determining region Y)-box 2 |
SPI1 | Spi-1 proto-oncogene |
SRPX | sushi-repeat containing protein, X-linked |
STOML2 | stomatin (EPB72)-like 2 |
TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
TAPBP | TAP binding protein (tapasin) |
TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 |
TF | transferrin |
TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
TGFB3 | transforming growth factor, beta 3 |
TIPIN | TIMELESS interacting protein |
TMEM106A | transmembrane protein 106A |
TREX1 | three prime repair exonuclease 1 |
UBE2C | ubiquitin-conjugating enzyme E2C |
USP15 | ubiquitin specific peptidase 15 |
VAMP5 | vesicle-associated membrane protein 5 |
WAS | Wiskott-Aldrich syndrome |
ZMYND19 | zinc finger, MYND-type containing 19 |
ZNFX1 | zinc finger, NFX1-type containing 1 |
ZWILCH | zwilch kinetochore protein |
Symbol | Name |
---|---|
ABCA4 | ATP-binding cassette, sub-family A (ABC1), member 4 |
ACYP2 | acylphosphatase 2, muscle type |
ANGPTL4 | angiopoietin-like 4 |
ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
ANXA8 | annexin A8 |
ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
ATP9A | ATPase, class II, type 9A |
BEX1 | brain expressed, X-linked 1 |
BNC1 | basonuclin 1 |
C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
C8ORF4 | chromosome 8 open reading frame 4 |
CACNB4 | calcium channel, voltage-dependent, beta 4 subunit |
CARD10 | caspase recruitment domain family, member 10 |
CBR3 | carbonyl reductase 3 |
CCDC109B | coiled-coil domain containing 109B |
CCR7 | chemokine (C-C motif) receptor 7 |
CD99L2 | CD99 molecule-like 2 |
CDH10 | cadherin 10, type 2 (T2-cadherin) |
CDKN2A | cyclin-dependent kinase inhibitor 2A |
CELF4 | CUGBP, Elav-like family member 4 |
CHODL | chondrolectin |
CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
CLCA1 | chloride channel accessory 1 |
CLEC1B | C-type lectin domain family 1, member B |
CNTN1 | contactin 1 |
CP | ceruloplasmin (ferroxidase) |
CRCT1 | cysteine-rich C-terminal 1 |
CRMP1 | collapsin response mediator protein 1 |
CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
CTH | cystathionine gamma-lyase |
CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) |
DES | desmin |
DIO2 | deiodinase, iodothyronine, type II |
DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
DNASE2 | deoxyribonuclease II, lysosomal |
DPEP1 | dipeptidase 1 (renal) |
DSG2 | desmoglein 2 |
DSP | desmoplakin |
EBF2 | early B-cell factor 2 |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
EFNA3 | ephrin-A3 |
ENO3 | enolase 3 (beta, muscle) |
ESR1 | estrogen receptor 1 |
FABP4 | fatty acid binding protein 4, adipocyte |
FADS3 | fatty acid desaturase 3 |
FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) |
FBLIM1 | filamin binding LIM protein 1 |
FGF13 | fibroblast growth factor 13 |
FLT4 | fms-related tyrosine kinase 4 |
FLYWCH2 | FLYWCH family member 2 |
FOXD1 | forkhead box D1 |
FOXG1 | forkhead box G1 |
FRZB | frizzled-related protein |
GABRB1 | gamma-aminobutyric acid (GABA) A receptor, beta 1 |
GATAD2A | GATA zinc finger domain containing 2A |
GDNF | glial cell derived neurotrophic factor |
GPX3 | glutathione peroxidase 3 |
GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
HOXA5 | homeobox A5 |
HOXB9 | homeobox B9 |
HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
IL11 | interleukin 11 |
IL13RA2 | interleukin 13 receptor, alpha 2 |
IL3RA | interleukin 3 receptor, alpha (low affinity) |
IRS4 | insulin receptor substrate 4 |
ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
ITGA7 | integrin, alpha 7 |
IVL | involucrin |
IZUMO1R | IZUMO1 receptor, JUNO |
KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
KIRREL | kin of IRRE like (Drosophila) |
KLK11 | kallikrein-related peptidase 11 |
KNG1 | kininogen 1 |
KRT18 | keratin 18, type I |
KRT27 | keratin 27, type I |
LMOD1 | leiomodin 1 (smooth muscle) |
LOC100129361 | |
LOXL4 | lysyl oxidase-like 4 |
LTB4R2 | leukotriene B4 receptor 2 |
LY75 | lymphocyte antigen 75 |
MALAT1 | metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) |
MAPK13 | mitogen-activated protein kinase 13 |
MGST2 | microsomal glutathione S-transferase 2 |
MMP10 | matrix metallopeptidase 10 |
MMP13 | matrix metallopeptidase 13 |
MMP3 | matrix metallopeptidase 3 |
MRVI1 | murine retrovirus integration site 1 homolog |
MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic |
MYLK | myosin light chain kinase |
NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta |
NIPAL2 | NIPA-like domain containing 2 |
NNMT | nicotinamide N-methyltransferase |
NPR1 | natriuretic peptide receptor 1 |
NPR3 | natriuretic peptide receptor 3 |
NSG1 | neuron specific gene family member 1 |
OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
OTUD7A | OTU deubiquitinase 7A |
P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
PANX1 | pannexin 1 |
PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
PDLIM5 | PDZ and LIM domain 5 |
PDZK1 | PDZ domain containing 1 |
PIP | prolactin-induced protein |
PKP1 | plakophilin 1 |
PKP2 | plakophilin 2 |
PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
PRKG2 | protein kinase, cGMP-dependent, type II |
PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
PTPRK | protein tyrosine phosphatase, receptor type, K |
PTPRVP | protein tyrosine phosphatase, receptor type, V, pseudogene |
PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
RABEPK | Rab9 effector protein with kelch motifs |
RAG2 | recombination activating gene 2 |
RAPGEF3 | Rap guanine nucleotide exchange factor (GEF) 3 |
RBP4 | retinol binding protein 4, plasma |
RCAN2 | regulator of calcineurin 2 |
RFX3 | regulatory factor X, 3 (influences HLA class II expression) |
RGS16 | regulator of G-protein signaling 16 |
RGS5 | regulator of G-protein signaling 5 |
RIMKLB | ribosomal modification protein rimK-like family member B |
RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
RRAD | Ras-related associated with diabetes |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
SH3RF1 | SH3 domain containing ring finger 1 |
SIM2 | single-minded family bHLH transcription factor 2 |
SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
SLC1A6 | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 |
SLC30A4 | solute carrier family 30 (zinc transporter), member 4 |
SLC38A10 | solute carrier family 38, member 10 |
SLC44A4 | solute carrier family 44, member 4 |
SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
SPEG | SPEG complex locus |
STAR | steroidogenic acute regulatory protein |
STK26 | serine/threonine protein kinase 26 |
STMN4 | stathmin-like 4 |
SYTL2 | synaptotagmin-like 2 |
TET1 | tet methylcytosine dioxygenase 1 |
TFPI2 | tissue factor pathway inhibitor 2 |
TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
TMEM176A | transmembrane protein 176A |
TMEM176B | transmembrane protein 176B |
TMEM53 | transmembrane protein 53 |
TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
TNNT2 | troponin T type 2 (cardiac) |
TPD52L1 | tumor protein D52-like 1 |
TRAPPC6A | trafficking protein particle complex 6A |
TRO | trophinin |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
VNN1 | vanin 1 |
WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 |
XIST | X inactive specific transcript (non-protein coding) |
YIPF2 | Yip1 domain family, member 2 |