SNU-423 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

267 genes with high or low expression in SNU-423 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
CUL4B cullin 4B 2.81237
CNN1 calponin 1, basic, smooth muscle 2.77991
LAMP2 lysosomal-associated membrane protein 2 2.73807
PSG6 pregnancy specific beta-1-glycoprotein 6 2.71434
MOSPD1 motile sperm domain containing 1 2.65678
TGFB2 transforming growth factor, beta 2 2.62699
PSG1 pregnancy specific beta-1-glycoprotein 1 2.47321
EDIL3 EGF-like repeats and discoidin I-like domains 3 2.34721
NABP1 nucleic acid binding protein 1 2.3389
TRIM58 tripartite motif containing 58 2.29294
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 2.28194
KISS1 KiSS-1 metastasis-suppressor 2.21947
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 2.17888
MMP24 matrix metallopeptidase 24 (membrane-inserted) 2.1465
PSG4 pregnancy specific beta-1-glycoprotein 4 2.13183
PSG9 pregnancy specific beta-1-glycoprotein 9 2.11568
PSG3 pregnancy specific beta-1-glycoprotein 3 2.11438
KLHL4 kelch-like family member 4 2.105
SRPX2 sushi-repeat containing protein, X-linked 2 2.07501
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 1.99164
FMO3 flavin containing monooxygenase 3 1.98048
BICC1 BicC family RNA binding protein 1 1.98044
MYH9 myosin, heavy chain 9, non-muscle 1.96512
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 1.93103
PSG5 pregnancy specific beta-1-glycoprotein 5 1.90195
SIM1 single-minded family bHLH transcription factor 1 1.86817
NXT2 nuclear transport factor 2-like export factor 2 1.85792
HLF hepatic leukemia factor 1.85733
RAP2C RAP2C, member of RAS oncogene family 1.81537
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 1.81051
COL4A1 collagen, type IV, alpha 1 1.8037
TENM2 teneurin transmembrane protein 2 1.7963
RBM3 RNA binding motif (RNP1, RRM) protein 3 1.77166
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 1.76664
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 1.7645
SYNPO2L synaptopodin 2-like 1.75427
PAWR PRKC, apoptosis, WT1, regulator 1.74312
FSTL3 follistatin-like 3 (secreted glycoprotein) 1.73596
ADAM12 ADAM metallopeptidase domain 12 1.72256
DYSF dysferlin 1.71444
PAMR1 peptidase domain containing associated with muscle regeneration 1 1.70853
GREM1 gremlin 1, DAN family BMP antagonist 1.70724
EPYC epiphycan 1.69462
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.69198
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 1.69096
FPR1 formyl peptide receptor 1 1.68579
SCML1 sex comb on midleg-like 1 (Drosophila) 1.67955
UGCG UDP-glucose ceramide glucosyltransferase 1.67356
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 1.6719
ATXN1 ataxin 1 1.66231
CPA4 carboxypeptidase A4 1.65453
SPDL1 spindle apparatus coiled-coil protein 1 1.63759
ORC3 origin recognition complex, subunit 3 1.63039
GLIPR1 GLI pathogenesis-related 1 1.5978
BDNF brain-derived neurotrophic factor 1.57977
ACSL4 acyl-CoA synthetase long-chain family member 4 1.56277
APP amyloid beta (A4) precursor protein 1.5622
PFDN1 prefoldin subunit 1 1.5601
CEP250 centrosomal protein 250kDa 1.54761
SFRP1 secreted frizzled-related protein 1 1.53992
ERCC6 excision repair cross-complementation group 6 1.53026
THBS1 thrombospondin 1 1.51615
TNC tenascin C 1.51051
SPEG SPEG complex locus 1.50237
PDLIM7 PDZ and LIM domain 7 (enigma) 1.50219
LIN28A lin-28 homolog A (C. elegans) 1.50136
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 1.50063
OLFML2A olfactomedin-like 2A 1.49951
ZSCAN26 zinc finger and SCAN domain containing 26 1.49759
EDN1 endothelin 1 1.48925
PSG2 pregnancy specific beta-1-glycoprotein 2 1.48547
EIF6 eukaryotic translation initiation factor 6 1.4853
GFRA1 GDNF family receptor alpha 1 1.48516
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 1.4755
PTGDS prostaglandin D2 synthase 21kDa (brain) 1.46053
TAGLN transgelin 1.45459
PPP4R2 protein phosphatase 4, regulatory subunit 2 1.43966
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 1.43961

low expression

Symbol Name Standardized Value
TSGA10 testis specific, 10 -2.74909
BMP7 bone morphogenetic protein 7 -2.69957
MFSD7 major facilitator superfamily domain containing 7 -2.68695
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus -2.61958
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein -2.555
THPO thrombopoietin -2.50572
CD80 CD80 molecule -2.46988
LEFTY1 left-right determination factor 1 -2.43338
GRAP GRB2-related adaptor protein -2.4277
MMP3 matrix metallopeptidase 3 -2.38199
CD53 CD53 molecule -2.36905
MYOM2 myomesin 2 -2.34387
RSPH14 radial spoke head 14 homolog (Chlamydomonas) -2.30431
CA2 carbonic anhydrase II -2.29802
S1PR5 sphingosine-1-phosphate receptor 5 -2.24681
MAN1C1 mannosidase, alpha, class 1C, member 1 -2.2426
AQP8 aquaporin 8 -2.18428
DUOX2 dual oxidase 2 -2.17974
GJB1 gap junction protein, beta 1, 32kDa -2.16647
ZP4 zona pellucida glycoprotein 4 -2.1354
PLCH2 phospholipase C, eta 2 -2.11733
ACP5 acid phosphatase 5, tartrate resistant -2.1153
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 -2.11118
RAB35 RAB35, member RAS oncogene family -2.10694
CELA3A chymotrypsin-like elastase family, member 3A -2.1038
GSTM5 glutathione S-transferase mu 5 -2.07946
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D -2.07371
DSCR4 Down syndrome critical region 4 -2.06304
PER1 period circadian clock 1 -2.04156
CUX2 cut-like homeobox 2 -2.03926
GDF9 growth differentiation factor 9 -2.02147
PTPRD protein tyrosine phosphatase, receptor type, D -2.01167
PAQR5 progestin and adipoQ receptor family member V -2.01036
KIAA1324 KIAA1324 -2.00952
AVP arginine vasopressin -2.00295
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 -1.99882
ANK1 ankyrin 1, erythrocytic -1.97464
CFHR4 complement factor H-related 4 -1.95113
COX6C cytochrome c oxidase subunit VIc -1.93987
DUSP9 dual specificity phosphatase 9 -1.93405
ARF1P1 ADP-ribosylation factor 1 pseudogene 1 -1.93238
OPRL1 opiate receptor-like 1 -1.91997
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 -1.91574
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 -1.91082
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 -1.90776
BEST1 bestrophin 1 -1.90732
IFNA13 interferon, alpha 13 -1.89994
TNNI2 troponin I type 2 (skeletal, fast) -1.89204
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 -1.88553
LIM2 lens intrinsic membrane protein 2, 19kDa -1.88538
GYPE glycophorin E (MNS blood group) -1.87505
VNN3 vanin 3 -1.873
MYCT1 myc target 1 -1.87288
MC5R melanocortin 5 receptor -1.86462
BMP3 bone morphogenetic protein 3 -1.86017
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -1.85953
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B -1.84722
AOC3 amine oxidase, copper containing 3 -1.8459
BCO1 beta-carotene oxygenase 1 -1.84407
TUBAL3 tubulin, alpha-like 3 -1.84173
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding) -1.83979
SOX30 SRY (sex determining region Y)-box 30 -1.83327
CDC14A cell division cycle 14A -1.82596
DLL3 delta-like 3 (Drosophila) -1.82298
RGSL1 regulator of G-protein signaling like 1 -1.80977
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -1.80575
IL19 interleukin 19 -1.80531
YEATS2 YEATS domain containing 2 -1.80365
DPH2 DPH2 homolog (S. cerevisiae) -1.80147
HUNK hormonally up-regulated Neu-associated kinase -1.79319
RRH retinal pigment epithelium-derived rhodopsin homolog -1.78641
LALBA lactalbumin, alpha- -1.78473
GDF3 growth differentiation factor 3 -1.78394
HBA1 hemoglobin, alpha 1 -1.77678
CLDN16 claudin 16 -1.77557
ADORA3 adenosine A3 receptor -1.77342
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 -1.75902
RCC1 regulator of chromosome condensation 1 -1.75286
MYO15B myosin XVB -1.75133
CORO2A coronin, actin binding protein, 2A -1.74601
GDF2 growth differentiation factor 2 -1.74123
HSPB3 heat shock 27kDa protein 3 -1.73754
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 -1.73655
TCAP titin-cap -1.72808
KLK12 kallikrein-related peptidase 12 -1.72443
OVGP1 oviductal glycoprotein 1, 120kDa -1.71822
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like -1.7024
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 -1.69785
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 -1.69766
TMPRSS2 transmembrane protease, serine 2 -1.69621
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -1.68971
MAGEF1 melanoma antigen family F1 -1.68591
SYN2 synapsin II -1.67988
CCL21 chemokine (C-C motif) ligand 21 -1.67914
TMOD2 tropomodulin 2 (neuronal) -1.67912
GPR153 G protein-coupled receptor 153 -1.67766
LGI2 leucine-rich repeat LGI family, member 2 -1.6745
MYNN myoneurin -1.67263
PRODH2 proline dehydrogenase (oxidase) 2 -1.66987
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -1.66944
MCHR1 melanin-concentrating hormone receptor 1 -1.66659
HAX1 HCLS1 associated protein X-1 -1.66624
S100G S100 calcium binding protein G -1.66523
DNTT DNA nucleotidylexotransferase -1.6641
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa -1.66262
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa -1.66155
RBM15 RNA binding motif protein 15 -1.65716
DHRS9 dehydrogenase/reductase (SDR family) member 9 -1.64962
CXCL11 chemokine (C-X-C motif) ligand 11 -1.64385
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -1.63815
FLJ42627 uncharacterized LOC645644 -1.62769
WISP1 WNT1 inducible signaling pathway protein 1 -1.62249
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -1.61943
SPRR3 small proline-rich protein 3 -1.61913
IFNA17 interferon, alpha 17 -1.61445
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha -1.61074
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 -1.60972
AGTR1 angiotensin II receptor, type 1 -1.6034
CSTB cystatin B (stefin B) -1.59988
VSNL1 visinin-like 1 -1.59775
FBRS fibrosin -1.59147
ARID1A AT rich interactive domain 1A (SWI-like) -1.59079
LDHC lactate dehydrogenase C -1.58655
NCAN neurocan -1.58606
EGFL6 EGF-like-domain, multiple 6 -1.58444
LBP lipopolysaccharide binding protein -1.58272
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) -1.58073
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -1.58022
ARSF arylsulfatase F -1.57474
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -1.57301
SH2D3C SH2 domain containing 3C -1.56918
AP1S1 adaptor-related protein complex 1, sigma 1 subunit -1.56658
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 -1.56351
EBAG9 estrogen receptor binding site associated, antigen, 9 -1.55926
ARG1 arginase 1 -1.55793
TLR3 toll-like receptor 3 -1.55749
DNASE2B deoxyribonuclease II beta -1.55367
OBP2A odorant binding protein 2A -1.54216
CA7 carbonic anhydrase VII -1.54081
RMST rhabdomyosarcoma 2 associated transcript (non-protein coding) -1.5406
GRIA2 glutamate receptor, ionotropic, AMPA 2 -1.53957
CRYGA crystallin, gamma A -1.53857
CTRB2 chymotrypsinogen B2 -1.53753
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 -1.53713
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -1.53511
CRYM crystallin, mu -1.53448
CD3D CD3d molecule, delta (CD3-TCR complex) -1.5327
ALAS2 5'-aminolevulinate synthase 2 -1.52659
HIGD1B HIG1 hypoxia inducible domain family, member 1B -1.52456
FOXJ1 forkhead box J1 -1.52362
COL5A3 collagen, type V, alpha 3 -1.51713
TNK1 tyrosine kinase, non-receptor, 1 -1.51426
OR2C1 olfactory receptor, family 2, subfamily C, member 1 -1.51006
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma -1.50807
AKT2 v-akt murine thymoma viral oncogene homolog 2 -1.5079
CCDC71 coiled-coil domain containing 71 -1.49819
MMP17 matrix metallopeptidase 17 (membrane-inserted) -1.49576
OR7C1 olfactory receptor, family 7, subfamily C, member 1 -1.49135
NELL1 NEL-like 1 (chicken) -1.48869
PZP pregnancy-zone protein -1.48866
GEMIN7 gem (nuclear organelle) associated protein 7 -1.48838
CYC1 cytochrome c-1 -1.48533
MMP27 matrix metallopeptidase 27 -1.48049
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 -1.47477
ANO1 anoctamin 1, calcium activated chloride channel -1.4713
CA5A carbonic anhydrase VA, mitochondrial -1.46648
INTS12 integrator complex subunit 12 -1.46567
LRRC32 leucine rich repeat containing 32 -1.46485
EVX1 even-skipped homeobox 1 -1.46329
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase -1.45996
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 -1.45845
JTB jumping translocation breakpoint -1.45513
LY6G6E lymphocyte antigen 6 complex, locus G6E (pseudogene) -1.45245
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -1.44865
KMT2D lysine (K)-specific methyltransferase 2D -1.44705
UBE2D3 ubiquitin-conjugating enzyme E2D 3 -1.44623
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -1.44222
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide -1.44217
TBXAS1 thromboxane A synthase 1 (platelet) -1.43792
SCN4A sodium channel, voltage gated, type IV alpha subunit -1.43656
AQP2 aquaporin 2 (collecting duct) -1.43567
COX5A cytochrome c oxidase subunit Va -1.42821
GNG13 guanine nucleotide binding protein (G protein), gamma 13 -1.42564
HPSE heparanase -1.42483
EPHX2 epoxide hydrolase 2, cytoplasmic -1.42377
PRND prion protein 2 (dublet) -1.41894
PAX4 paired box 4 -1.41756
UPB1 ureidopropionase, beta -1.41625
GRPR gastrin-releasing peptide receptor -1.41587