SNU-449 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

248 genes with high or low expression in SNU-449 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
MAPK7 mitogen-activated protein kinase 7 3.59104
ADRA1B adrenoceptor alpha 1B 3.5634
B9D1 B9 protein domain 1 3.03585
CNTNAP3B contactin associated protein-like 3B 2.98539
RAB40B RAB40B, member RAS oncogene family 2.73585
IAPP islet amyloid polypeptide 2.71211
FRMD4A FERM domain containing 4A 2.61647
KRTAP5-8 keratin associated protein 5-8 2.59411
EPN2 epsin 2 2.57056
PARD3 par-3 family cell polarity regulator 2.53909
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 2.38595
ERCC2 excision repair cross-complementation group 2 2.37212
HABP4 hyaluronan binding protein 4 2.31881
FZD2 frizzled class receptor 2 2.29571
ADAP2 ArfGAP with dual PH domains 2 2.29231
PADI2 peptidyl arginine deiminase, type II 2.28217
RBPMS RNA binding protein with multiple splicing 2.27146
MORC4 MORC family CW-type zinc finger 4 2.13963
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 2.13268
IVNS1ABP influenza virus NS1A binding protein 2.12508
WNT2 wingless-type MMTV integration site family member 2 2.12322
BEAN1 brain expressed, associated with NEDD4, 1 2.09062
RGS7 regulator of G-protein signaling 7 2.08451
PADI3 peptidyl arginine deiminase, type III 2.0731
CEP250 centrosomal protein 250kDa 2.07291
RGS9 regulator of G-protein signaling 9 2.04506
BMP5 bone morphogenetic protein 5 2.03967
KIRREL kin of IRRE like (Drosophila) 2.03819
FGFR1 fibroblast growth factor receptor 1 2.00275
MSL3 male-specific lethal 3 homolog (Drosophila) 1.97474
AQP1 aquaporin 1 (Colton blood group) 1.95786
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) 1.956
ARF6 ADP-ribosylation factor 6 1.93918
PPME1 protein phosphatase methylesterase 1 1.91864
SCARA3 scavenger receptor class A, member 3 1.90701
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 1.90643
RGN regucalcin 1.87186
NMT1 N-myristoyltransferase 1 1.87173
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 1.87069
DDAH2 dimethylarginine dimethylaminohydrolase 2 1.86397
GIP gastric inhibitory polypeptide 1.86247
COL13A1 collagen, type XIII, alpha 1 1.85936
BMP3 bone morphogenetic protein 3 1.85358
UBTD1 ubiquitin domain containing 1 1.81734
DFNB31 deafness, autosomal recessive 31 1.7835
IRGC immunity-related GTPase family, cinema 1.78236
FGF5 fibroblast growth factor 5 1.77907
GNG5 guanine nucleotide binding protein (G protein), gamma 5 1.75491
RLN2 relaxin 2 1.75357
BCO1 beta-carotene oxygenase 1 1.73815
FXYD2 FXYD domain containing ion transport regulator 2 1.72417
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 1.70135
NMT2 N-myristoyltransferase 2 1.6889
OXTR oxytocin receptor 1.67485
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 1.67178
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 1.67099
GRB14 growth factor receptor-bound protein 14 1.66472
DNM1 dynamin 1 1.65524
ORC4 origin recognition complex, subunit 4 1.64458
RAB5C RAB5C, member RAS oncogene family 1.64216
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 1.63618
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 1.62687
CNN1 calponin 1, basic, smooth muscle 1.6161
PTH1R parathyroid hormone 1 receptor 1.61322
MRS2 MRS2 magnesium transporter 1.61099
TMUB2 transmembrane and ubiquitin-like domain containing 2 1.609
SLCO1A2 solute carrier organic anion transporter family, member 1A2 1.60028
NT5DC3 5'-nucleotidase domain containing 3 1.59435
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 1.59245
HAVCR1 hepatitis A virus cellular receptor 1 1.58758
PBLD phenazine biosynthesis-like protein domain containing 1.58356
DIO3 deiodinase, iodothyronine, type III 1.57249
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 1.57036
FMNL2 formin-like 2 1.56696
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) 1.56
LTBP2 latent transforming growth factor beta binding protein 2 1.54401
ATRNL1 attractin-like 1 1.53831
NUP85 nucleoporin 85kDa 1.53802
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 1.53643
HNF1B HNF1 homeobox B 1.53432
EIF6 eukaryotic translation initiation factor 6 1.53151
FJX1 four jointed box 1 (Drosophila) 1.53146
PAOX polyamine oxidase (exo-N4-amino) 1.52599
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 1.52522
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.52174
VASP vasodilator-stimulated phosphoprotein 1.52125
LHX1 LIM homeobox 1 1.5106
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 1.50666
CD3EAP CD3e molecule, epsilon associated protein 1.50373
LPP LIM domain containing preferred translocation partner in lipoma 1.50358
SYT13 synaptotagmin XIII 1.50238
PDGFB platelet-derived growth factor beta polypeptide 1.49668
PON2 paraoxonase 2 1.49652
MMP24 matrix metallopeptidase 24 (membrane-inserted) 1.4933
RSU1 Ras suppressor protein 1 1.49034
VAV3 vav 3 guanine nucleotide exchange factor 1.48837
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 1.48367
SPAG9 sperm associated antigen 9 1.48277
NR5A2 nuclear receptor subfamily 5, group A, member 2 1.48086
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 1.479
SEC14L1 SEC14-like 1 (S. cerevisiae) 1.47409
PDE1B phosphodiesterase 1B, calmodulin-dependent 1.47363
NENF neudesin neurotrophic factor 1.47319
ECHDC3 enoyl CoA hydratase domain containing 3 1.47256
GPR132 G protein-coupled receptor 132 1.46716
FLNA filamin A, alpha 1.46683
SAE1 SUMO1 activating enzyme subunit 1 1.46485
MAOB monoamine oxidase B 1.46147
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 1.46047
SAP30BP SAP30 binding protein 1.45749
WNT5B wingless-type MMTV integration site family, member 5B 1.45338
FANCC Fanconi anemia, complementation group C 1.45282
TGFB1I1 transforming growth factor beta 1 induced transcript 1 1.45242
PGC progastricsin (pepsinogen C) 1.44947
SNF8 SNF8, ESCRT-II complex subunit 1.44895
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) 1.44824
LIMS2 LIM and senescent cell antigen-like domains 2 1.4477
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) 1.44494
BICC1 BicC family RNA binding protein 1 1.44352
SPON2 spondin 2, extracellular matrix protein 1.44256
NLE1 notchless homolog 1 (Drosophila) 1.43956
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 1.43536
MTCL1 microtubule crosslinking factor 1 1.43382
PRG3 proteoglycan 3 1.4337
RABIF RAB interacting factor 1.43273
PON1 paraoxonase 1 1.43199
ARSE arylsulfatase E (chondrodysplasia punctata 1) 1.42991
TAZ tafazzin 1.42922
CCNJL cyclin J-like 1.4265
NIPSNAP1 nipsnap homolog 1 (C. elegans) 1.42622
DENND2A DENN/MADD domain containing 2A 1.42558
GFRA1 GDNF family receptor alpha 1 1.42375
PTH2R parathyroid hormone 2 receptor 1.42334
TMEM40 transmembrane protein 40 1.42219
PACS2 phosphofurin acidic cluster sorting protein 2 1.42047
BFSP1 beaded filament structural protein 1, filensin 1.42003
CEP55 centrosomal protein 55kDa 1.42001
FXYD6 FXYD domain containing ion transport regulator 6 1.41974
PSG5 pregnancy specific beta-1-glycoprotein 5 1.41822
PDZD7 PDZ domain containing 7 1.41711

low expression

Symbol Name Standardized Value
HIST1H2BO histone cluster 1, H2bo -3.46137
TTC4 tetratricopeptide repeat domain 4 -3.11511
LINS lines homolog (Drosophila) -2.94245
TMEM59 transmembrane protein 59 -2.92251
CRYBB2 crystallin, beta B2 -2.79121
ZBTB33 zinc finger and BTB domain containing 33 -2.75635
INTS6 integrator complex subunit 6 -2.71508
PCDH11X protocadherin 11 X-linked -2.45371
NECAP1 NECAP endocytosis associated 1 -2.41843
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa -2.37089
CHMP4A charged multivesicular body protein 4A -2.29527
HIST1H2AJ histone cluster 1, H2aj -2.29123
PLXNA2 plexin A2 -2.27217
SEC62 SEC62 homolog (S. cerevisiae) -2.2227
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -2.19271
PPID peptidylprolyl isomerase D -2.13943
LMO2 LIM domain only 2 (rhombotin-like 1) -2.1276
HK2 hexokinase 2 -2.10099
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.08941
GRM8 glutamate receptor, metabotropic 8 -2.08357
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -2.07138
ACOT11 acyl-CoA thioesterase 11 -2.04468
MRPS31 mitochondrial ribosomal protein S31 -2.04192
NFYB nuclear transcription factor Y, beta -1.94616
UFM1 ubiquitin-fold modifier 1 -1.93242
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -1.91843
SRPR signal recognition particle receptor (docking protein) -1.89376
PDE4DIP phosphodiesterase 4D interacting protein -1.88694
FOCAD focadhesin -1.86577
TMPRSS6 transmembrane protease, serine 6 -1.86539
RAB36 RAB36, member RAS oncogene family -1.85746
ARMCX3 armadillo repeat containing, X-linked 3 -1.84729
SOX30 SRY (sex determining region Y)-box 30 -1.83659
UBL3 ubiquitin-like 3 -1.83173
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -1.82288
NPPA natriuretic peptide A -1.80523
ATP11B ATPase, class VI, type 11B -1.79674
ZNF230 zinc finger protein 230 -1.79547
KRTAP4-7 keratin associated protein 4-7 -1.77308
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 -1.76574
EDA ectodysplasin A -1.74079
BTBD1 BTB (POZ) domain containing 1 -1.73978
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease -1.71958
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -1.71323
FNBP4 formin binding protein 4 -1.70654
HOXA4 homeobox A4 -1.70504
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) -1.69362
CLINT1 clathrin interactor 1 -1.69013
IFT20 intraflagellar transport 20 -1.68354
CDADC1 cytidine and dCMP deaminase domain containing 1 -1.67628
HOXB9 homeobox B9 -1.66815
SYCP2 synaptonemal complex protein 2 -1.66627
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 -1.66497
CD4 CD4 molecule -1.65805
MEOX2 mesenchyme homeobox 2 -1.62757
IL7 interleukin 7 -1.60698
SIT1 signaling threshold regulating transmembrane adaptor 1 -1.60619
IGSF6 immunoglobulin superfamily, member 6 -1.59642
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -1.59562
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) -1.59064
LIN7C lin-7 homolog C (C. elegans) -1.59038
OSBPL11 oxysterol binding protein-like 11 -1.58696
SND1-IT1 SND1 intronic transcript 1 -1.58686
HOXC11 homeobox C11 -1.57678
ING2 inhibitor of growth family, member 2 -1.57607
ATF7 activating transcription factor 7 -1.56218
PDE3A phosphodiesterase 3A, cGMP-inhibited -1.5571
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -1.55306
ADAM29 ADAM metallopeptidase domain 29 -1.55022
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -1.54833
GAS2 growth arrest-specific 2 -1.54119
SAP18 Sin3A-associated protein, 18kDa -1.54064
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 -1.53975
STAP1 signal transducing adaptor family member 1 -1.53974
TMED3 transmembrane emp24 protein transport domain containing 3 -1.53797
CHAT choline O-acetyltransferase -1.53505
FYN FYN proto-oncogene, Src family tyrosine kinase -1.5332
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -1.53228
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -1.52665
GP5 glycoprotein V (platelet) -1.52104
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -1.52068
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -1.51461
MDFI MyoD family inhibitor -1.51314
F12 coagulation factor XII (Hageman factor) -1.51083
FOLR1 folate receptor 1 (adult) -1.50596
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -1.50579
TPTE transmembrane phosphatase with tensin homology -1.50312
CLCN3 chloride channel, voltage-sensitive 3 -1.502
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 -1.49385
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa -1.48927
UGT8 UDP glycosyltransferase 8 -1.48555
GH2 growth hormone 2 -1.4846
ZMYM2 zinc finger, MYM-type 2 -1.48379
VGF VGF nerve growth factor inducible -1.47956
ZXDC ZXD family zinc finger C -1.47907
SRPRB signal recognition particle receptor, B subunit -1.47842
MAGEF1 melanoma antigen family F1 -1.47723
EED embryonic ectoderm development -1.4723
ZFC3H1 zinc finger, C3H1-type containing -1.46897
NPHP4 nephronophthisis 4 -1.46172
SATB1 SATB homeobox 1 -1.46033
KIAA0430 KIAA0430 -1.45279
EGF epidermal growth factor -1.43377
BTG1 B-cell translocation gene 1, anti-proliferative -1.43121
HIST2H2AA3 histone cluster 2, H2aa3 -1.42678
GIF gastric intrinsic factor (vitamin B synthesis) -1.42251
TMEM33 transmembrane protein 33 -1.42145
PARP11 poly (ADP-ribose) polymerase family, member 11 -1.4178