SNU-C2B Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: colorectal carcinoma (Cell Line Ontology, CLO_0009105)
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Genes

267 genes with high or low expression in SNU-C2B relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 3.48185
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 2.87775
NTS neurotensin 2.57937
DIO3 deiodinase, iodothyronine, type III 2.56519
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.50912
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 2.43646
SREBF1 sterol regulatory element binding transcription factor 1 2.32479
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 2.22221
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 2.16287
PREP prolyl endopeptidase 2.16094
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 2.15795
FN3K fructosamine 3 kinase 2.15114
LGALS2 lectin, galactoside-binding, soluble, 2 2.11079
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1 2.10412
GEMIN4 gem (nuclear organelle) associated protein 4 2.0858
TNNI2 troponin I type 2 (skeletal, fast) 2.06852
BCAP31 B-cell receptor-associated protein 31 2.03824
ADCY6 adenylate cyclase 6 2.02094
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 2.01001
ARMC7 armadillo repeat containing 7 2.00447
EFNB1 ephrin-B1 1.99508
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 1.97859
SHPK sedoheptulokinase 1.96316
PMM2 phosphomannomutase 2 1.95395
PTCD1 pentatricopeptide repeat domain 1 1.93589
TNK1 tyrosine kinase, non-receptor, 1 1.92174
PI3 peptidase inhibitor 3, skin-derived 1.8871
HYPK huntingtin interacting protein K 1.87116
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 1.86959
GMDS GDP-mannose 4,6-dehydratase 1.8606
RFX5 regulatory factor X, 5 (influences HLA class II expression) 1.85352
HDDC2 HD domain containing 2 1.8412
IL17RB interleukin 17 receptor B 1.84073
L2HGDH L-2-hydroxyglutarate dehydrogenase 1.83997
PHF10 PHD finger protein 10 1.83522
LLGL2 lethal giant larvae homolog 2 (Drosophila) 1.8332
AKAP3 A kinase (PRKA) anchor protein 3 1.83211
ERN2 endoplasmic reticulum to nucleus signaling 2 1.82442
CREB3L1 cAMP responsive element binding protein 3-like 1 1.81397
CALB1 calbindin 1, 28kDa 1.8131
C2CD2L C2CD2-like 1.808
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 1.80612
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G 1.79571
TRIP10 thyroid hormone receptor interactor 10 1.78395
MUC1 mucin 1, cell surface associated 1.76795
SLC39A7 solute carrier family 39 (zinc transporter), member 7 1.75362
SLC44A4 solute carrier family 44, member 4 1.75071
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 1.74939
SEMG1 semenogelin I 1.74694
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 1.73621
CLCN2 chloride channel, voltage-sensitive 2 1.72117
GPA33 glycoprotein A33 (transmembrane) 1.71934
EIF4E eukaryotic translation initiation factor 4E 1.71154
DAZAP1 DAZ associated protein 1 1.70856
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 1.70168
HMBS hydroxymethylbilane synthase 1.7008
HMOX2 heme oxygenase 2 1.69484
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 1.69388
LEFTY1 left-right determination factor 1 1.6906
PEX7 peroxisomal biogenesis factor 7 1.68435
INPP1 inositol polyphosphate-1-phosphatase 1.68256
RWDD1 RWD domain containing 1 1.66261
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 1.65386
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 1.64101
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 1.63623
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 1.63617
NMT1 N-myristoyltransferase 1 1.63201
TM9SF4 transmembrane 9 superfamily protein member 4 1.6276
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 1.62644
KRT8P12 keratin 8 pseudogene 12 1.6252
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 1.62196
CTPS2 CTP synthase 2 1.61317
CANT1 calcium activated nucleotidase 1 1.59968
SHB Src homology 2 domain containing adaptor protein B 1.59857
EDF1 endothelial differentiation-related factor 1 1.5931
GIGYF2 GRB10 interacting GYF protein 2 1.58695
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 1.58112
TBC1D10B TBC1 domain family, member 10B 1.57452
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 1.57383
KPNA1 karyopherin alpha 1 (importin alpha 5) 1.56902
SPIN2A spindlin family, member 2A 1.56643
DKK4 dickkopf WNT signaling pathway inhibitor 4 1.56419
PTS 6-pyruvoyltetrahydropterin synthase 1.55755
POF1B premature ovarian failure, 1B 1.55394
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.55255
SFTPB surfactant protein B 1.55132
SEMG2 semenogelin II 1.54671
PLLP plasmolipin 1.54598
LDLR low density lipoprotein receptor 1.54566
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 1.53768
DLG3 discs, large homolog 3 (Drosophila) 1.53377
TERF2 telomeric repeat binding factor 2 1.53304
TST thiosulfate sulfurtransferase (rhodanese) 1.52061
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 1.51935
EPHA2 EPH receptor A2 1.519
AAAS achalasia, adrenocortical insufficiency, alacrimia 1.51583
LAD1 ladinin 1 1.51157
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 1.5023
NLRX1 NLR family member X1 1.50222
PLXNB2 plexin B2 1.50184
TFF2 trefoil factor 2 1.49712
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 1.49095
EHF ets homologous factor 1.48938
ZBTB7A zinc finger and BTB domain containing 7A 1.48803
OASL 2'-5'-oligoadenylate synthetase-like 1.48508
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 1.48435
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 1.48417
TSPAN8 tetraspanin 8 1.48416
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 1.48301
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 1.47332
SPAG1 sperm associated antigen 1 1.47062
CEP55 centrosomal protein 55kDa 1.47013
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.46713
MARC2 mitochondrial amidoxime reducing component 2 1.46317
MRPS12 mitochondrial ribosomal protein S12 1.46282
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 1.45089
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 1.44918
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E 1.44701
S100A4 S100 calcium binding protein A4 1.44663
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 1.44647
ATP10B ATPase, class V, type 10B 1.44467
TPM3 tropomyosin 3 1.44273
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 1.44049
CEP170B centrosomal protein 170B 1.43981
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 1.43898
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 1.43598
CCDC86 coiled-coil domain containing 86 1.43142
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 1.42814
KLF2 Kruppel-like factor 2 1.42693
FAAH fatty acid amide hydrolase 1.42582
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 1.41988
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 1.41879
TPD52L1 tumor protein D52-like 1 1.41692

low expression

Symbol Name Standardized Value
OXSR1 oxidative stress responsive 1 -3.53666
RPL15 ribosomal protein L15 -2.87285
SIGLEC15 sialic acid binding Ig-like lectin 15 -2.82133
TUG1 taurine up-regulated 1 (non-protein coding) -2.71771
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -2.63939
CLASP2 cytoplasmic linker associated protein 2 -2.59003
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) -2.57752
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -2.53733
EIF1B eukaryotic translation initiation factor 1B -2.51703
ZNF83 zinc finger protein 83 -2.50731
GPX1 glutathione peroxidase 1 -2.43114
NNT nicotinamide nucleotide transhydrogenase -2.36915
MSH2 mutS homolog 2 -2.36062
TTC37 tetratricopeptide repeat domain 37 -2.35577
SLFN12 schlafen family member 12 -2.346
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 -2.28953
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.2686
ZNF665 zinc finger protein 665 -2.24736
ANGEL2 angel homolog 2 (Drosophila) -2.2365
MR1 major histocompatibility complex, class I-related -2.21234
TBC1D19 TBC1 domain family, member 19 -2.16587
MXRA8 matrix-remodelling associated 8 -2.16239
JAK1 Janus kinase 1 -2.12441
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) -2.11979
MCFD2 multiple coagulation factor deficiency 2 -2.10384
GPR157 G protein-coupled receptor 157 -2.10252
POGZ pogo transposable element with ZNF domain -2.10195
DPYSL4 dihydropyrimidinase-like 4 -2.09267
PDE4B phosphodiesterase 4B, cAMP-specific -2.08991
SOCS2 suppressor of cytokine signaling 2 -2.08843
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -2.06714
REM1 RAS (RAD and GEM)-like GTP-binding 1 -2.0651
ZNF225 zinc finger protein 225 -2.06195
ZNF136 zinc finger protein 136 -2.04511
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -2.02997
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -2.02659
CEP63 centrosomal protein 63kDa -2.01846
IFT140 intraflagellar transport 140 -2.00928
C1RL complement component 1, r subcomponent-like -1.99305
TPP1 tripeptidyl peptidase I -1.98679
ZNF423 zinc finger protein 423 -1.97509
DIO2 deiodinase, iodothyronine, type II -1.93471
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 -1.9273
MSH6 mutS homolog 6 -1.92497
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 -1.92467
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -1.90582
ZNF529 zinc finger protein 529 -1.90183
CDC5L cell division cycle 5-like -1.88955
KRBOX4 KRAB box domain containing 4 -1.87154
ZNF223 zinc finger protein 223 -1.86904
USP11 ubiquitin specific peptidase 11 -1.86527
KIF3A kinesin family member 3A -1.83556
PCDH9 protocadherin 9 -1.81162
ALOX5AP arachidonate 5-lipoxygenase-activating protein -1.80428
BBS10 Bardet-Biedl syndrome 10 -1.79735
HIST1H2BG histone cluster 1, H2bg -1.79235
APOE apolipoprotein E -1.7882
FABP3 fatty acid binding protein 3, muscle and heart -1.78792
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 -1.78084
ORAI2 ORAI calcium release-activated calcium modulator 2 -1.77754
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 -1.77618
CLEC4E C-type lectin domain family 4, member E -1.77192
RB1CC1 RB1-inducible coiled-coil 1 -1.77164
CPQ carboxypeptidase Q -1.7646
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 -1.75983
PREPL prolyl endopeptidase-like -1.7484
TMEM14B transmembrane protein 14B -1.74559
TBC1D5 TBC1 domain family, member 5 -1.74422
RANBP6 RAN binding protein 6 -1.73439
AGTR1 angiotensin II receptor, type 1 -1.72671
SEC14L1 SEC14-like 1 (S. cerevisiae) -1.72166
PODNL1 podocan-like 1 -1.72039
MAP3K12 mitogen-activated protein kinase kinase kinase 12 -1.71038
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) -1.70751
IGFALS insulin-like growth factor binding protein, acid labile subunit -1.69796
DNAH7 dynein, axonemal, heavy chain 7 -1.68014
RECQL RecQ helicase-like -1.67871
CPNE7 copine VII -1.66569
RAB5A RAB5A, member RAS oncogene family -1.66502
FXR1 fragile X mental retardation, autosomal homolog 1 -1.64626
EMID1 EMI domain containing 1 -1.64453
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -1.64423
MEOX1 mesenchyme homeobox 1 -1.60757
ZNF277 zinc finger protein 277 -1.59725
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 -1.59409
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa -1.59099
HLA-A major histocompatibility complex, class I, A -1.5652
ZNF37BP zinc finger protein 37B, pseudogene -1.55864
WDR5B WD repeat domain 5B -1.5554
CBR4 carbonyl reductase 4 -1.55377
NR1D2 nuclear receptor subfamily 1, group D, member 2 -1.55258
HDAC5 histone deacetylase 5 -1.55115
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 -1.55057
GPX3 glutathione peroxidase 3 -1.54903
GOLGA4 golgin A4 -1.53882
CD36 CD36 molecule (thrombospondin receptor) -1.53425
TBXA2R thromboxane A2 receptor -1.53267
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -1.52602
WDR77 WD repeat domain 77 -1.52357
SARM1 sterile alpha and TIR motif containing 1 -1.52327
GSDMD gasdermin D -1.51786
CRTAC1 cartilage acidic protein 1 -1.50172
BLMH bleomycin hydrolase -1.50158
USP24 ubiquitin specific peptidase 24 -1.50044
KIAA1462 KIAA1462 -1.49817
MED25 mediator complex subunit 25 -1.49771
PVALB parvalbumin -1.49591
CARD9 caspase recruitment domain family, member 9 -1.49235
HLA-DMB major histocompatibility complex, class II, DM beta -1.48981
PFKP phosphofructokinase, platelet -1.48801
ESR2 estrogen receptor 2 (ER beta) -1.48693
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 -1.48647
ADCY2 adenylate cyclase 2 (brain) -1.48001
PLIN2 perilipin 2 -1.47752
ZNF468 zinc finger protein 468 -1.46905
RTN2 reticulon 2 -1.46452
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -1.46435
MRC2 mannose receptor, C type 2 -1.4613
NOS1 nitric oxide synthase 1 (neuronal) -1.46042
STX8 syntaxin 8 -1.45267
MDK midkine (neurite growth-promoting factor 2) -1.45082
CARF calcium responsive transcription factor -1.44904
AMELX amelogenin, X-linked -1.44815
ZNF137P zinc finger protein 137, pseudogene -1.44465
CHD1 chromodomain helicase DNA binding protein 1 -1.44411
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) -1.44027
RTN1 reticulon 1 -1.43865
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 -1.43656
BNC2 basonuclin 2 -1.43575
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -1.43522
POT1 protection of telomeres 1 -1.43476
CLSTN3 calsyntenin 3 -1.43461
STON1 stonin 1 -1.43
PDGFD platelet derived growth factor D -1.42057