SNU398 Gene Set

Dataset DepMap CRISPR Gene Dependency
Category disease or phenotype associations
Type cell line
External Link https://depmap.org/portal/cell_line/ACH-000221
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Genes

522 gene knockdowns changing fitness of SNU398 relative to other cell lines from the DepMap CRISPR Gene Dependency Dataset.

Symbol Name Standardized Value
TRIB3 tribbles pseudokinase 3 22.3231
ATOX1 antioxidant 1 copper chaperone 13.3738
RHOT2 ras homolog family member T2 10.1657
TPST1 tyrosylprotein sulfotransferase 1 10.0813
LGALS7 lectin, galactoside-binding, soluble, 7 9.39204
NAT16 N-acetyltransferase 16 (GCN5-related, putative) 9.3755
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 8.64177
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 8.52466
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 8.36007
LPPR5 lipid phosphate phosphatase-related protein type 5 8.26686
POMK protein-O-mannose kinase 7.51935
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 7.33455
TMEM252 transmembrane protein 252 6.90086
STRN4 striatin, calmodulin binding protein 4 6.842
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 6.72894
SPATA13 spermatogenesis associated 13 6.49225
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 6.21615
PILRB paired immunoglobin-like type 2 receptor beta 6.09852
CENPV centromere protein V 6.07958
DGKZ diacylglycerol kinase, zeta 5.9777
SLC12A9 solute carrier family 12, member 9 5.9287
SIPA1L3 signal-induced proliferation-associated 1 like 3 5.87123
FOXG1 forkhead box G1 5.86006
LY6G6C lymphocyte antigen 6 complex, locus G6C 5.77717
TMEM145 transmembrane protein 145 5.76961
PILRA paired immunoglobin-like type 2 receptor alpha 5.76768
KRT32 keratin 32, type I 5.62738
LTK leukocyte receptor tyrosine kinase 5.61995
SGSM1 small G protein signaling modulator 1 5.60531
PRSS35 protease, serine, 35 5.60085
SACK1F scaffolding CK1 anchoring protein F 5.48305
FUS FUS RNA binding protein 5.44856
PRODH proline dehydrogenase (oxidase) 1 5.44671
AGFG2 ArfGAP with FG repeats 2 5.44134
DACT3 dishevelled-binding antagonist of beta-catenin 3 5.38652
DMPK dystrophia myotonica-protein kinase 5.36158
HEMK1 HemK methyltransferase family member 1 5.34162
INPP5K inositol polyphosphate-5-phosphatase K 5.33777
GTPBP1 GTP binding protein 1 5.32452
FAM57B family with sequence similarity 57, member B 5.30285
NACAD NAC alpha domain containing 5.30067
DRD5 dopamine receptor D5 5.22798
PCIF1 PDX1 C-terminal inhibiting factor 1 5.20649
TBRG4 transforming growth factor beta regulator 4 5.12219
KIAA1549L KIAA1549-like 5.08979
CGAS cyclic GMP-AMP synthase 5.08385
MICU1 mitochondrial calcium uptake 1 5.02561
DGUOK deoxyguanosine kinase 4.99427
PRRT2 proline-rich transmembrane protein 2 4.98523
ACHE acetylcholinesterase (Yt blood group) 4.96372
PROK1 prokineticin 1 4.95117
ICK intestinal cell (MAK-like) kinase 4.9473
BICD1 bicaudal D homolog 1 (Drosophila) 4.92126
TXN2 thioredoxin 2 4.90533
PRICKLE1 prickle homolog 1 (Drosophila) 4.89007
CMSS1 cms1 ribosomal small subunit homolog (yeast) 4.87606
GP1BA glycoprotein Ib (platelet), alpha polypeptide 4.87063
ADAT1 adenosine deaminase, tRNA-specific 1 4.82979
NUGGC nuclear GTPase, germinal center associated 4.8042
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 4.75206
HPSE heparanase 4.73732
DLX5 distal-less homeobox 5 4.71343
C2ORF40 chromosome 2 open reading frame 40 4.68105
IRX3 iroquois homeobox 3 4.65921
RAG1 recombination activating gene 1 4.64184
TTC17 tetratricopeptide repeat domain 17 4.6209
GTPBP2 GTP binding protein 2 4.59967
TXNDC17 thioredoxin domain containing 17 4.58428
ETV1 ets variant 1 4.55687
KLHDC8B kelch domain containing 8B 4.53324
GLIS1 GLIS family zinc finger 1 4.50764
ASTL astacin-like metallo-endopeptidase (M12 family) 4.50636
PRAMEF2 PRAME family member 2 4.4634
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 4.40889
ZP3 zona pellucida glycoprotein 3 (sperm receptor) 4.35717
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 4.29479
C11ORF58 chromosome 11 open reading frame 58 4.28928
TBL2 transducin (beta)-like 2 4.28861
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 4.28315
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 4.27536
TSPAN2 tetraspanin 2 4.26028
MRGPRX4 MAS-related GPR, member X4 4.25211
IGFBPL1 insulin-like growth factor binding protein-like 1 4.21751
CCL14 chemokine (C-C motif) ligand 14 4.18901
TMEM150C transmembrane protein 150C 4.187
MOGAT3 monoacylglycerol O-acyltransferase 3 4.14169
ACCSL 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like 4.11949
HMBS hydroxymethylbilane synthase 4.10518
SLFN11 schlafen family member 11 4.05235
NOS1 nitric oxide synthase 1 (neuronal) 4.04606
FIMP1 fertilization-influencing membrane protein 1 4.03701
MDP1 magnesium-dependent phosphatase 1 4.02648
WDR6 WD repeat domain 6 3.99857
TP53I11 tumor protein p53 inducible protein 11 3.99241
TBX3 T-box 3 3.98834
TMEM185B transmembrane protein 185B 3.98613
FAM214B family with sequence similarity 214, member B 3.97398
VDAC2 voltage-dependent anion channel 2 3.95082
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 3.94906
HLA-F major histocompatibility complex, class I, F 3.92412
C1ORF111 chromosome 1 open reading frame 111 3.92303
PHKG1 phosphorylase kinase, gamma 1 (muscle) 3.9225
CLDN7 claudin 7 3.92025
LMTK2 lemur tyrosine kinase 2 3.84346
ROR2 receptor tyrosine kinase-like orphan receptor 2 3.83099
ZNF708 zinc finger protein 708 3.82723
LUZP2 leucine zipper protein 2 3.81931
VPS37D vacuolar protein sorting 37 homolog D (S. cerevisiae) 3.79434
GIGYF1 GRB10 interacting GYF protein 1 3.76228
RTKN rhotekin 3.7334
PROC protein C (inactivator of coagulation factors Va and VIIIa) 3.73253
TMPRSS2 transmembrane protease, serine 2 3.73183
FBXW9 F-box and WD repeat domain containing 9 3.72229
SCNN1B sodium channel, non voltage gated 1 beta subunit 3.71727
KIF7 kinesin family member 7 3.69692
PROSER2 proline and serine rich 2 3.66377
VWA3B von Willebrand factor A domain containing 3B 3.65144
LRRC4B leucine rich repeat containing 4B 3.64612
MRGPRX3 MAS-related GPR, member X3 3.64142
MLXIPL MLX interacting protein-like 3.62847
CCDC34 coiled-coil domain containing 34 3.61684
MRPL1 mitochondrial ribosomal protein L1 3.61441
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 3.61215
PSG2 pregnancy specific beta-1-glycoprotein 2 3.61028
DCC DCC netrin 1 receptor 3.60918
IGFBP7 insulin-like growth factor binding protein 7 3.60713
ATP7A ATPase, Cu++ transporting, alpha polypeptide 3.60597
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 3.58371
TCEANC transcription elongation factor A (SII) N-terminal and central domain containing 3.5684
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 3.55988
TGIF2 TGFB-induced factor homeobox 2 3.55546
OVGP1 oviductal glycoprotein 1, 120kDa 3.5526
LYPD6 LY6/PLAUR domain containing 6 3.52489
C11ORF94 chromosome 11 open reading frame 94 3.51703
PALM3 paralemmin 3 3.49109
PCDHGB3 protocadherin gamma subfamily B, 3 3.49027
ITGA9 integrin, alpha 9 3.4804
FNDC7 fibronectin type III domain containing 7 3.47141
BCL9 B-cell CLL/lymphoma 9 3.4542
CAPG capping protein (actin filament), gelsolin-like 3.44202
MPV17L2 MPV17 mitochondrial membrane protein-like 2 3.42838
CYBB cytochrome b-245, beta polypeptide 3.41857
SPATA21 spermatogenesis associated 21 3.41486
ELMOD3 ELMO/CED-12 domain containing 3 3.41421
SUN3 Sad1 and UNC84 domain containing 3 3.39789
SBK1 SH3 domain binding kinase 1 3.39518
ALX4 ALX homeobox 4 3.39401
TMEM87B transmembrane protein 87B 3.38208
RTN2 reticulon 2 3.37803
PHIP pleckstrin homology domain interacting protein 3.33572
KCNIP3 Kv channel interacting protein 3, calsenilin 3.33278
MBLAC2 metallo-beta-lactamase domain containing 2 3.32615
NCAN neurocan 3.3217
SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13 3.31042
SLC35F6 solute carrier family 35, member F6 3.31005
MTIF3 mitochondrial translational initiation factor 3 3.3009
NCMAP noncompact myelin associated protein 3.29984
CCDC74B coiled-coil domain containing 74B 3.29138
KRCC1 lysine-rich coiled-coil 1 3.29081
TAAR6 trace amine associated receptor 6 3.27872
SHROOM3 shroom family member 3 3.27423
ARHGEF39 Rho guanine nucleotide exchange factor (GEF) 39 3.27201
ASL argininosuccinate lyase 3.26721
NME6 NME/NM23 nucleoside diphosphate kinase 6 3.2658
LIG3 ligase III, DNA, ATP-dependent 3.25973
C7ORF25 chromosome 7 open reading frame 25 3.248
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 3.2335
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 3.2273
NADK2 NAD kinase 2, mitochondrial 3.21552
NR6A1 nuclear receptor subfamily 6, group A, member 1 3.21523
SFXN1 sideroflexin 1 3.21027
PNMA8B PNMA family member 8B 3.20332
TCF21 transcription factor 21 3.19789
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 3.19227
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 3.1909
ZBTB47 zinc finger and BTB domain containing 47 3.18249
NAXE NAD(P)HX epimerase 3.17004
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 3.16127
ACTL6B actin-like 6B 3.15331
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 3.11852
RERG RAS-like, estrogen-regulated, growth inhibitor 3.11136
MRPS36 mitochondrial ribosomal protein S36 3.11091
TSPAN11 tetraspanin 11 3.10772
KHDC1 KH homology domain containing 1 3.09528
TAOK2 TAO kinase 2 3.08742
LRP11 low density lipoprotein receptor-related protein 11 3.08383
BOK BCL2-related ovarian killer 3.08049
SYPL2 synaptophysin-like 2 3.06815
HOXD9 homeobox D9 3.06146
PRICKLE2 prickle homolog 2 (Drosophila) 3.06086
ZNF713 zinc finger protein 713 3.05261
APOC1 apolipoprotein C-I 3.05208
RUNDC1 RUN domain containing 1 3.05082
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 3.04966
CENPJ centromere protein J 3.04923
OR6C2 olfactory receptor, family 6, subfamily C, member 2 3.04511
TTC7B tetratricopeptide repeat domain 7B 3.04369
FOXRED1 FAD-dependent oxidoreductase domain containing 1 3.03846
POSTN periostin, osteoblast specific factor 3.0253
FCRL2 Fc receptor-like 2 3.01723
TMC2 transmembrane channel-like 2 3.00972
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase 3.00795
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 3.00482
CENPQ centromere protein Q 3.00314
SGCE sarcoglycan, epsilon 2.99769
C20ORF85 chromosome 20 open reading frame 85 2.99717
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D 2.99494
GJA5 gap junction protein, alpha 5, 40kDa 2.99323
RPUSD3 RNA pseudouridylate synthase domain containing 3 2.98185
DEDD2 death effector domain containing 2 2.97888
ASPH aspartate beta-hydroxylase 2.96097
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 2.95745
CSF1 colony stimulating factor 1 (macrophage) 2.95723
FAM78B family with sequence similarity 78, member B 2.95495
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 2.94947
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 2.94663
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 2.94599
ACAD9 acyl-CoA dehydrogenase family, member 9 2.94593
BAZ2A bromodomain adjacent to zinc finger domain, 2A 2.9392
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2.93172
SIAE sialic acid acetylesterase 2.93074
ZNF658 zinc finger protein 658 2.92848
MECR mitochondrial trans-2-enoyl-CoA reductase 2.92329
MS4A8 membrane-spanning 4-domains, subfamily A, member 8 2.92317
G6PD glucose-6-phosphate dehydrogenase 2.91882
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 2.91878
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 2.90404
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 2.89396
CELF3 CUGBP, Elav-like family member 3 2.8887
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 2.88546
NAT8 N-acetyltransferase 8 (GCN5-related, putative) 2.88545
S100A4 S100 calcium binding protein A4 2.87934
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 2.87778
MBLAC1 metallo-beta-lactamase domain containing 1 2.87553
STEEP1 STING1 ER exit protein 1 2.87203
DENND2C DENN/MADD domain containing 2C 2.86067
APLNR apelin receptor 2.85016
AGBL2 ATP/GTP binding protein-like 2 2.84964
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 2.82934
PCDHGA10 protocadherin gamma subfamily A, 10 2.82826
CHRDL2 chordin-like 2 2.82742
NWD1 NACHT and WD repeat domain containing 1 2.82278
TF transferrin 2.82142
TFB1M transcription factor B1, mitochondrial 2.81715
RASA2 RAS p21 protein activator 2 2.81513
PSD4 pleckstrin and Sec7 domain containing 4 2.81423
GTF3C6 general transcription factor IIIC, polypeptide 6, alpha 35kDa 2.80591
EGF epidermal growth factor 2.80108
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 2.80094
MAG myelin associated glycoprotein 2.79602
TRPV2 transient receptor potential cation channel, subfamily V, member 2 2.7855
CRP C-reactive protein, pentraxin-related 2.78453
ZNF736 zinc finger protein 736 2.78355
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 2.78044
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 2.77403
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 2.77332
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 2.77174
GOLGA4 golgin A4 2.76929
OR4B1 olfactory receptor, family 4, subfamily B, member 1 2.76489
LRRC46 leucine rich repeat containing 46 2.75915
CCDC142 coiled-coil domain containing 142 2.7438
FIBCD1 fibrinogen C domain containing 1 2.73601
FAHD2A fumarylacetoacetate hydrolase domain containing 2A 2.73264
FSCN1 fascin actin-bundling protein 1 2.73021
LRRC8A leucine rich repeat containing 8 family, member A 2.72661
GGCX gamma-glutamyl carboxylase 2.72013
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 2.71912
GJA1 gap junction protein, alpha 1, 43kDa 2.71594
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 2.71377
FBXO45 F-box protein 45 2.70944
PSG5 pregnancy specific beta-1-glycoprotein 5 2.70743
GJD4 gap junction protein, delta 4, 40.1kDa 2.70101
TMEM11 transmembrane protein 11 2.69913
AFF3 AF4/FMR2 family, member 3 2.69896
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa 2.69775
CLVS1 clavesin 1 2.68924
UCN urocortin 2.68418
SCARB2 scavenger receptor class B, member 2 2.68043
TMEM132E transmembrane protein 132E 2.67673
NPC1L1 NPC1-like 1 2.67158
FAM181A family with sequence similarity 181, member A 2.66943
CLDN15 claudin 15 2.66518
SCN8A sodium channel, voltage gated, type VIII alpha subunit 2.6559
AQP10 aquaporin 10 2.64066
EPB42 erythrocyte membrane protein band 4.2 2.62192
HSPA6 heat shock 70kDa protein 6 (HSP70B') 2.61667
GOLGA7 golgin A7 2.6112
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 2.6092
SV2A synaptic vesicle glycoprotein 2A 2.59783
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 2.59631
CS citrate synthase 2.59454
C1RL complement component 1, r subcomponent-like 2.5882
TOMM70 translocase of outer mitochondrial membrane 70 2.58713
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 2.58539
LRRD1 leucine-rich repeats and death domain containing 1 2.58139
DUOXA2 dual oxidase maturation factor 2 2.57712
FASTKD5 FAST kinase domains 5 2.57384
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 2.57213
STAT5A signal transducer and activator of transcription 5A 2.56986
PCLO piccolo presynaptic cytomatrix protein 2.56953
RSBN1L round spermatid basic protein 1-like 2.56858
LAMB2 laminin, beta 2 (laminin S) 2.5666
SZT2 seizure threshold 2 homolog (mouse) 2.56336
CBY1 chibby homolog 1 (Drosophila) 2.55331
TECPR1 tectonin beta-propeller repeat containing 1 2.553
RASL11A RAS-like, family 11, member A 2.55054
USP17L13 ubiquitin specific peptidase 17-like family member 13 2.54622
CCDC51 coiled-coil domain containing 51 2.54414
BCL2L2 BCL2-like 2 2.53543
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 2.53336
ECE1 endothelin converting enzyme 1 2.53315
AQP1 aquaporin 1 (Colton blood group) 2.53136
LGALSL lectin, galactoside-binding-like 2.53011
CPOX coproporphyrinogen oxidase 2.52391
SAP25 Sin3A-associated protein, 25kDa 2.51986
SLMO1 slowmo homolog 1 (Drosophila) 2.51487
PIEZO1 piezo-type mechanosensitive ion channel component 1 2.50867
GANC glucosidase, alpha; neutral C 2.50422
ACD adrenocortical dysplasia homolog (mouse) 2.50383
AEBP1 AE binding protein 1 2.49954
PLCD1 phospholipase C, delta 1 2.49945
MFSD6 major facilitator superfamily domain containing 6 2.4989
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 2.49798
CSRNP3 cysteine-serine-rich nuclear protein 3 2.49213
CA8 carbonic anhydrase VIII 2.48938
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 2.48937
FBXL18 F-box and leucine-rich repeat protein 18 2.48719
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 2.48647
PRMT2IP PRMT2 interacting protein 2.48581
POLR1D polymerase (RNA) I polypeptide D, 16kDa 2.48579
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 2.48554
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 2.48551
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 2.48426
GSTM3 glutathione S-transferase mu 3 (brain) 2.4829
RBP3 retinol binding protein 3, interstitial 2.48234
LIG1 ligase I, DNA, ATP-dependent 2.47771
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C 2.47657
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 2.47412
MOV10 Mov10 RISC complex RNA helicase 2.47262
ZEB2 zinc finger E-box binding homeobox 2 2.47185
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 2.46934
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 2.46907
COQ8B coenzyme Q8B 2.46801
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 2.46342
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 2.46129
TEX101 testis expressed 101 2.46122
HCCS holocytochrome c synthase 2.45567
IL9 interleukin 9 2.45486
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 2.45461
HIGD2A HIG1 hypoxia inducible domain family, member 2A 2.4525
CEP97 centrosomal protein 97kDa 2.44859
VSIG8 V-set and immunoglobulin domain containing 8 2.44214
TSPAN5 tetraspanin 5 2.44034
MTL5 metallothionein-like 5, testis-specific (tesmin) 2.44021
HIRIP3 HIRA interacting protein 3 2.433
TRIM45 tripartite motif containing 45 2.4323
AP2B1 adaptor-related protein complex 2, beta 1 subunit 2.42475
CD33 CD33 molecule 2.42352
PALB2 partner and localizer of BRCA2 2.42294
PGM1 phosphoglucomutase 1 2.41322
YPEL3 yippee-like 3 (Drosophila) 2.4109
OR51D1 olfactory receptor, family 51, subfamily D, member 1 2.40632
TEX22 testis expressed 22 2.40206
FCRL3 Fc receptor-like 3 2.3917
IL6R interleukin 6 receptor 2.38669
TRIM55 tripartite motif containing 55 2.38457
IL27 interleukin 27 2.37474
MMP17 matrix metallopeptidase 17 (membrane-inserted) 2.37219
PARL presenilin associated, rhomboid-like 2.36568
NOA1 nitric oxide associated 1 2.36538
HKDC1 hexokinase domain containing 1 2.36248
TMIGD3 transmembrane and immunoglobulin domain containing 3 2.3618
CD101 CD101 molecule 2.35801
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 2.35684
C17ORF74 chromosome 17 open reading frame 74 2.35557
POLG polymerase (DNA directed), gamma 2.35423
GREM1 gremlin 1, DAN family BMP antagonist 2.3514
MADD MAP-kinase activating death domain 2.33903
STAP1 signal transducing adaptor family member 1 2.33727
BAIAP2L1 BAI1-associated protein 2-like 1 2.3252
THEGL theg spermatid protein-like 2.32146
EPS8L3 EPS8-like 3 2.32096
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 2.31394
PYGO2 pygopus family PHD finger 2 2.3138
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 2.31217
ECSIT ECSIT signalling integrator 2.30831
KCTD7 potassium channel tetramerization domain containing 7 2.30612
MYL12B myosin, light chain 12B, regulatory 2.30503
MACROH2A1 macroH2A.1 histone 2.30252
C2ORF54 chromosome 2 open reading frame 54 2.30215
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 2.30199
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 2.30156
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 2.30125
OXSM 3-oxoacyl-ACP synthase, mitochondrial 2.30075
RTN4IP1 reticulon 4 interacting protein 1 2.29642
HDGFL2 HDGF like 2 2.29592
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6 2.28986
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2.28842
HYI hydroxypyruvate isomerase (putative) 2.28761
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 2.28264
GBP3 guanylate binding protein 3 2.28145
ZCCHC5 zinc finger, CCHC domain containing 5 2.28132
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 2.27952
RASL12 RAS-like, family 12 2.27753
MRM2 mitochondrial rRNA methyltransferase 2 2.27456
TUBG2 tubulin, gamma 2 2.26739
OR4N2 olfactory receptor, family 4, subfamily N, member 2 2.26337
PPAPDC3 phosphatidic acid phosphatase type 2 domain containing 3 2.26006
CREG2 cellular repressor of E1A-stimulated genes 2 2.25844
TBX6 T-box 6 2.25701
SP5 Sp5 transcription factor 2.25061
CCP110 centriolar coiled coil protein 110kDa 2.2503
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 2.24869
OLA1 Obg-like ATPase 1 2.24733
ATXN7L3 ataxin 7-like 3 2.2473
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) 2.2465
ARHGAP23 Rho GTPase activating protein 23 2.24643
SH2B3 SH2B adaptor protein 3 2.24367
XKR4 XK, Kell blood group complex subunit-related family, member 4 2.2419
EGFLAM EGF-like, fibronectin type III and laminin G domains 2.23902
TEKT4 tektin 4 2.22994
ZNF747 zinc finger protein 747 2.22698
FILIP1 filamin A interacting protein 1 2.224
OR4C12 olfactory receptor, family 4, subfamily C, member 12 2.22192
NPR2 natriuretic peptide receptor 2 2.21955
FUT10 fucosyltransferase 10 (alpha (1,3) fucosyltransferase) 2.20619
SDC3 syndecan 3 2.20605
LHX6 LIM homeobox 6 2.20595
WDR4 WD repeat domain 4 2.20235
GSTM2 glutathione S-transferase mu 2 (muscle) 2.19832
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) 2.18709
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 2.18344
PTPDC1 protein tyrosine phosphatase domain containing 1 2.1833
PITRM1 pitrilysin metallopeptidase 1 2.18199
HTRA4 HtrA serine peptidase 4 2.17701
SLC16A4 solute carrier family 16, member 4 2.17643
CISH cytokine inducible SH2-containing protein 2.1758
ANKHD1 ankyrin repeat and KH domain containing 1 2.17061
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) 2.17013
OGA O-GlcNAcase 2.16702
TERT telomerase reverse transcriptase 2.16023
MME membrane metallo-endopeptidase 2.15936
ERCC8 excision repair cross-complementation group 8 2.15922
HK1 hexokinase 1 2.15813
MTFMT mitochondrial methionyl-tRNA formyltransferase 2.15572
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 2.15525
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10 2.15465
CAPNS1 calpain, small subunit 1 2.15209
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 2.15104
KRT33A keratin 33A, type I 2.13651
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 2.13098
DCAF10 DDB1 and CUL4 associated factor 10 2.12951
PRDM5 PR domain containing 5 2.12938
LYPD1 LY6/PLAUR domain containing 1 2.12792
SERTAD1 SERTA domain containing 1 2.12566
PBX2 pre-B-cell leukemia homeobox 2 2.12548
POU4F3 POU class 4 homeobox 3 2.11528
TUBA3C tubulin, alpha 3c 2.11326
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 2.11248
ZGRF1 zinc finger, GRF-type containing 1 2.11211
CES1 carboxylesterase 1 2.10823
IKBIP IKBKB interacting protein 2.10613
FLT3 fms-related tyrosine kinase 3 2.1048
ZNF785 zinc finger protein 785 2.10241
NAF1 nuclear assembly factor 1 ribonucleoprotein 2.10225
AOC2 amine oxidase, copper containing 2 (retina-specific) 2.10166
MIPEP mitochondrial intermediate peptidase 2.10108
NCBP3 nuclear cap binding subunit 3 2.0977
NYAP1 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1 2.09582
MTERF3 mitochondrial transcription termination factor 3 2.09491
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y 2.09383
LIME1 Lck interacting transmembrane adaptor 1 2.09201
ACACA acetyl-CoA carboxylase alpha 2.08737
CXXC1 CXXC finger protein 1 2.0851
GJA10 gap junction protein, alpha 10, 62kDa 2.08124
NPTXR neuronal pentraxin receptor 2.0802
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 2.07564
ETV2 ets variant 2 2.07331
PRR19 proline rich 19 2.07194
SYT1 synaptotagmin I 2.07144
AMER3 APC membrane recruitment protein 3 2.06888
DPH6 diphthamine biosynthesis 6 2.0609
C6ORF52 chromosome 6 open reading frame 52 2.05983
ZNF37A zinc finger protein 37A 2.05953
IGSF22 immunoglobulin superfamily, member 22 2.0567
PITX3 paired-like homeodomain 3 2.05372
MYG1 MYG1 exonuclease 2.05196
PF4 platelet factor 4 2.05018
IRF9 interferon regulatory factor 9 2.04936
SERGEF secretion regulating guanine nucleotide exchange factor 2.04899
STOX1 storkhead box 1 2.04886
OLIG1 oligodendrocyte transcription factor 1 2.04855
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 2.04711
DDB2 damage-specific DNA binding protein 2, 48kDa 2.04366
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 2.04306
ESRRA estrogen-related receptor alpha 2.04055
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 2.03875
ASF1A anti-silencing function 1A histone chaperone 2.03808
HARBI1 harbinger transposase derived 1 2.03536
RRAD Ras-related associated with diabetes 2.03488
MVB12B multivesicular body subunit 12B 2.03427
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 2.03366
LURAP1 leucine rich adaptor protein 1 2.03089
TMEM54 transmembrane protein 54 2.02841
C7ORF43 chromosome 7 open reading frame 43 2.02782
PCDHB15 protocadherin beta 15 2.02595
TRIM56 tripartite motif containing 56 2.02481
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2.02435
CCL5 chemokine (C-C motif) ligand 5 2.02043
HOMER3 homer scaffolding protein 3 2.02019
HARS2 histidyl-tRNA synthetase 2, mitochondrial 2.01741
ARF6 ADP-ribosylation factor 6 2.01468
COA3 cytochrome c oxidase assembly factor 3 2.01446
ABHD11 abhydrolase domain containing 11 2.0128
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.01249
TRABD2B TraB domain containing 2B 2.011
CLMB calcimembrin 2.00933
AKAP12 A kinase (PRKA) anchor protein 12 2.00849
CHTOP chromatin target of PRMT1 2.00515
BDNF brain-derived neurotrophic factor 2.00431
PLEKHA7 pleckstrin homology domain containing, family A member 7 2.00382
PALMD palmdelphin 2.00074